Junior Faculty Engagement at iSchools: Personal Experience during the First Several Years

This roundtable discussion will explore how junior faculty at iSchools have been able to embed their research, teaching, and service activities within their schools, the larger institutions, and broader communities. The session will also focus on the ways in which junior faculty have received guidance in their roles--from the job search through the first several years in a tenure-track position. Roundtable leaders represent a variety of institutions and experiences--as faculty at the University of Illinois at Urbana-Champaign [WJM], the University of Maryland [SP], the University of North Carolina at Chapel Hill [PME], and the University of Texas at Austin [MW], and with doctoral-level preparation at the University of North Carolina at Chapel Hill [WJM, MW], the University of Toronto [SP], and the University of Washington [PME]. While the annual junior faculty mentoring event at the iConference specifically targets junior faculty as participants, this roundtable session offers a more inclusive environment for the discussion of this topic, specifically engaging doctoral students and senior faculty as well as their junior colleagues

ALTERNATE HIGH EFFICIENCY PARTICULATE AIR (HEPA) FILTRATION SYSTEM

In Phase IIA of this project, CeraMem has further developed and scaled up ceramic HEPA filters that are appropriate for use on filtration of vent gas from HLW tanks at DOE sites around the country. This work included procuring recrystallized SiC monoliths, developing membrane and cement materials, and defining a manufacturing process for the production of prototype full sizes HEPA filters. CeraMem has demonstrated that prototype full size filters can be manufactured by producing 9 full size filters that passed DOP aerosol testing at the Oak Ridge Filter Test Facility. One of these filters was supplied to the Savannah River Technical Center (SRTC) for process tests using simulated HLW tank waste. SRTC has reported that the filter was regenerable (with some increase in pressure drop) and that the filter retained its HEPA retention capability. CeraMem has also developed a Regenerable HEPA Filter System (RHFS) design and acceptance test plan that was reviewed by DOE personnel. The design and acceptance test plan form the basis of the system proposal for follow-on work in Phase IIB of this project

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

[This corrects the article DOI: 10.18632/oncotarget.7702.]

Correction: Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.

[This corrects the article DOI: 10.18632/oncotarget.7702.]

SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations

To elucidate whether tyrosine kinase inhibitor (TKI) resistance in chronic myeloid leukemia is associated with characteristic genomic alterations, we analyzed DNA samples from 45 TKI-resistant chronic myeloid leukemia patients with 250K single nucleotide polymorphism arrays. From 20 patients, matched serial samples of pretreatment and TKI resistance time points were available. Eleven of the 45 TKI-resistant patients had mutations of BCR-ABL1, including 2 T315I mutations. Besides known TKI resistance-associated genomic lesions, such as duplication of the BCR-ABL1 gene (n = 8) and trisomy 8 (n = 3), recurrent submicroscopic alterations, including acquired uniparental disomy, were detectable on chromosomes 1, 8, 9, 17, 19, and 22. On chromosome 22, newly acquired and recurrent deletions of the IGLC1 locus were detected in 3 patients, who had previously presented with lymphoid or myeloid blast crisis. This may support a hypothesis of TKI-induced selection of subclones differentiating into immature B-cell progenitors as a mechanism of disease progression and evasion of TKI sensitivity

Everyday victimization of adolescent girls by boys: sexual harassment, bullying or aggression?

School-based sexual harassment of adolescent girls by boys appears commonplace, yet aggression and bullying studies rarely yield sexualized material. This qualitative Australian study with 72 14- to 15-year-olds and 7 teachers aimed to discover whether interviewer use of neutral language in gender-segregated focus groups and interviews would yield material indicating that the victimization of girls by boys is sexualized. Verbal and indirect victimization were reported to be everyday occurrences, and almost entirely sexual. Findings are discussed in the light of definitions of sexual harassment, bullying and aggression. It is concluded that the term "sexual bullying" appropriately captures the gendered power structure underlying these behaviors. As such, they need to be understood, and become visible, more broadly than in terms of individual pathology. © 2007 Springer Science+Business Media, LLC.C