324 research outputs found
Evaluation of contamination for extraneous materials in âsun meatâ sold in the âhouses of the northâ in the municipality of Diadema (SP, Brazil)
The âsun meatâ is a handmade product, combining surface techniques of salting and dehydration, commonly used by people from the North and Northeast regions of Brazil. The sun meat cooking process lacks in sophisticated technology and official standards of procedure and quality. Thus, production, sale and distribution under unsatisfactory sanitary conditions are risky to the consumersâ health. This paper is aimed at evaluating the sanitary conditions of âsun meatâ sold at the âhouses of the northâ for the presence of extraneous materials. Analysis of 44 samples of âsun meatâ from 22 âhouses of the northâ located in âDiadema Districtâ (SP, Brazil) had been carried out. The product conditions of exposure and sale in the âhouses of the northâ were evaluated and provided additional information to assess the degree of food safety of this product. In 44 samples were found various types of extraneous materials such as whole insects and debris, larvae, exuvia, mites, rodent hairs, bird feather pieces, fungi, and sharp objects. Mechanical vectors were observed at 11 locations of the sale area. The results indicated that 90.9% of the âsun meatâ has unsatisfactory sanitary conditions, caused by the presence of physical hazards of contamination. These results, associated with conditions found in the âhouses of the northâ, indicated that these products can put the health of consumers at risk. Keywords: Sun meat, Sanitary Conditions, Food security
Estimated time of death through the cadaveric entomofauna in decomposing cadavers: a case report
This study reports a case of a sixty-nine years old lady who was found dead in her house, in state ofputrefaction. The study of cadaveric phenomena was imprecise and determined the post mortem time as two weeks and some days. The entomofauna analysis resulted to be a more accurate cronotanatognosis method, showing that the death had occurred exactly eight days before the body was found.Relato do caso de uma senhora de sessenta e nove anos encontrada morta em sua residĂȘncia, jĂĄ em estado de putrefação, no qual a anĂĄlise dos fenĂŽmenos cadavĂ©ricos foi imprecisa para determinar a cronotanatognose (de dois dias a algumas semanas). Foi, entĂŁo, realizado o estudo da entomofauna cadavĂ©rica para determinar o PMI (post morten interval) e concluiu-se que a morte havia ocorrido oito dias antes
Are sEMG, Velocity and Power Influenced by Athletesâ Fixation in Paralympic Powerlifting?
The bench press is performed in parapowerlifting with the back, shoulders, buttocks, legs and heels extended over the bench, and the use of straps to secure the athlete to the bench is optional. Thus, the study evaluated muscle activation, surface electromyography (sEMG), maximum velocity (MaxV) and mean propulsive velocity (MPV), and power in paralympic powerlifting athletes under conditions tied or untied to the bench. Fifteen experienced Paralympic powerlifting male athletes (22.27 ± 10.30 years, 78.5 ± 21.6 kg) took part in the research. The sEMG measurement was performed in the sternal portion of the pectoralis major (PMES), anterior deltoid (AD), long head of the triceps brachii (TRI) and clavicular portion of the pectoralis major (PMCL). The MaxV, MPV and power were evaluated using an encoder. Loads of 40%, 60%, 80% and 100% 1RM were analyzed under untied and tied conditions. No differences were found in muscle activation between the tied and untied conditions; however, sEMG showed differences in the untied condition between AD and TRI (F (3112) = 4.484; p = 0.005) in the 100% 1RM load, between PMCL and AD (F (3112) = 3.743; p = 0.013) in 60% 1RM load and in the tied condition, between the PMES and the AD (F (3112) = 4.067; p = 0.009). There were differences in MaxV (F (3112) = 213.3; p < 0.001), and MPV (F (3112) = 248.2; p < 0.001), between all loads in the tied and untied condition. In power, the load of 100% 1RM differed from all other relative loads (F (3112) = 36.54; p < 0.001) in both conditions. The tied condition seems to favor muscle activation, sEMG, and velocity over the untied condition
Piccolo genotype modulates neural correlates of emotion processing but not executive functioning
Major depressive disorder (MDD) is characterized by affective symptoms and cognitive impairments, which have been associated with changes in limbic and prefrontal activity as well as with monoaminergic neurotransmission. A genome-wide association study implicated the polymorphism rs2522833 in the piccolo (PCLO) geneâinvolved in monoaminergic neurotransmissionâas a risk factor for MDD. However, the role of the PCLO risk allele in emotion processing and executive function or its effect on their neural substrate has never been studied. We used functional magnetic resonance imaging (fMRI) to investigate PCLO risk allele carriers vs noncarriers during an emotional face processing task and a visuospatial planning task in 159 current MDD patients and healthy controls. In PCLO risk allele carriers, we found increased activity in the left amygdala during processing of angry and sad faces compared with noncarriers, independent of psychopathological status. During processing of fearful faces, the PCLO risk allele was associated with increased amygdala activation in MDD patients only. During the visuospatial planning task, we found no genotype effect on performance or on BOLD signal in our predefined areas as a function of increasing task load. The PCLO risk allele was found to be specifically associated with altered emotion processing, but not with executive dysfunction. Moreover, the PCLO risk allele appears to modulate amygdala function during fearful facial processing in MDD and may constitute a possible link between genotype and susceptibility for depression via altered processing of fearful stimuli. The current results may therefore aid in better understanding underlying neurobiological mechanisms in MDD
International longitudinal registry of patients with atrial fibrillation and treated with rivaroxaban: RIVaroxaban Evaluation in Real life setting (RIVER)
Background
Real-world data on non-vitamin K oral anticoagulants (NOACs) are essential in determining whether evidence from randomised controlled clinical trials translate into meaningful clinical benefits for patients in everyday practice. RIVER (RIVaroxaban Evaluation in Real life setting) is an ongoing international, prospective registry of patients with newly diagnosed non-valvular atrial fibrillation (NVAF) and at least one investigator-determined risk factor for stroke who received rivaroxaban as an initial treatment for the prevention of thromboembolic stroke. The aim of this paper is to describe the design of the RIVER registry and baseline characteristics of patients with newly diagnosed NVAF who received rivaroxaban as an initial treatment.
Methods and results
Between January 2014 and June 2017, RIVER investigators recruited 5072 patients at 309 centres in 17 countries. The aim was to enroll consecutive patients at sites where rivaroxaban was already routinely prescribed for stroke prevention. Each patient is being followed up prospectively for a minimum of 2-years. The registry will capture data on the rate and nature of all thromboembolic events (stroke / systemic embolism), bleeding complications, all-cause mortality and other major cardiovascular events as they occur. Data quality is assured through a combination of remote electronic monitoring and onsite monitoring (including source data verification in 10% of cases). Patients were mostly enrolled by cardiologists (n =â3776, 74.6%), by internal medicine specialists 14.2% (n =â718) and by primary care/general practice physicians 8.2% (n =â417). The mean (SD) age of the population was 69.5 (11.0) years, 44.3% were women. Mean (SD) CHADS2 score was 1.9 (1.2) and CHA2DS2-VASc scores was 3.2 (1.6). Almost all patients (98.5%) were prescribed with once daily dose of rivaroxaban, most commonly 20âmg (76.5%) and 15âmg (20.0%) as their initial treatment; 17.9% of patients received concomitant antiplatelet therapy. Most patients enrolled in RIVER met the recommended threshold for AC therapy (86.6% for 2012 ESC Guidelines, and 79.8% of patients according to 2016 ESC Guidelines).
Conclusions
The RIVER prospective registry will expand our knowledge of how rivaroxaban is prescribed in everyday practice and whether evidence from clinical trials can be translated to the broader cross-section of patients in the real world
Interpretative and predictive modelling of Joint European Torus collisionality scans
Transport modelling of Joint European Torus (JET) dimensionless collisionality scaling experiments in various operational scenarios is presented. Interpretative simulations at a fixed radial position are combined with predictive JETTO simulations of temperatures and densities, using the TGLF transport model. The model includes electromagnetic effects and collisions as well as âĄ(ââŹE ) X âĄ(ââŹB ) shear in Miller geometry. Focus is on particle transport and the role of the neutral beam injection (NBI) particle source for the density peaking. The experimental 3-point collisionality scans include L-mode, and H-mode (D and H and higher beta D plasma) plasmas in a total of 12 discharges. Experimental results presented in (Tala et al 2017 44th EPS Conf.) indicate that for the H-mode scans, the NBI particle source plays an important role for the density peaking, whereas for the L-mode scan, the influence of the particle source is small. In general, both the interpretative and predictive transport simulations support the experimental conclusions on the role of the NBI particle source for the 12 JET discharges
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Track A Basic Science
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd
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