4 research outputs found
The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity
Precise synthesis of molecularly defined oligomers and polymers by orthogonal iterative divergent/convergent approaches
International audienceThe synthesis of perfectly defined (macro)molecules has been a constant challenge for polymer and organic chemists. This paper highlights the main applications of the iterative divergent/ convergent approach for the synthesis of discrete mass oligomers and polymers. We will discuss the orthogonal deprotection and coupling strategies involved in this powerful strategy where chain length doubles at each iteration and which has been applied to the synthesis of conjugated rigid rods as well as amorphous and crystalline oligomers and polymers. The synthesis of perfectly defined oligomers in respect to emerging highly efficient and orthogonal chemistries will also be highlighted