Partial adaptation to the value range in the macaque orbitofrontal cortex

Values available for choice in different behavioral contexts can vary immensely. To compensate for this variability, neuronal circuits underlying economic decisions undergo adaptation. In orbitofrontal cortex (OFC), neurons encode the subjective value of offered and chosen goods in a quasilinear way. Previous experiments found that the gain of the encoding is lower when the value range is wider. However, the parameters OFC neurons adapted to remained unclear. Furthermore, previous studies did not examine additive changes in neuronal responses. Computational considerations indicate that these factors can directly impact choice behavior. Here we investigated how OFC neurons adapt to changes in the value range. We recorded from two male rhesus monkeys during a juice choice task. Each session was divided into two blocks of trials. In each block, juices were offered within a set range of values, and ranges changed between blocks. Across blocks, neuronal responses adapted to both the maximum and the minimum value, but only partially. As a result, the minimum neural activity was elevated in some value ranges relative to others. Through simulation of a linear decision model, we showed that increasing the minimum response increases choice variability, lowering the expected payoff. This effect is modulated by the balance between cells with positive and negative encoding. The presence of these two populations induces a non-monotonic relationship between the value range and choice efficacy, such that the expected payoff is highest for decisions in an intermediate value range

Deformation history of the blueschist-facies sequences from the Villa de Cura unit (Northern Venezuela)

The Serrania del Interior terrane is located in Northern Venezuela, that represents the southern margin of the Caribbean plate. This terrane includes the Villa de Cura unit, which mainly consists of multiple sub-units of metamorphosed and deformed Cretaceous volcano-sedimentary sequences. These sequences are commonly interpreted as generated in a supra-subduction zone setting. The structural history of the Villa de Cura blueschists-facies units includes four main deformational phases, from D1 to D4. The first D1 phase is mainly represented by a relict S1 schistosity developed under HP/LT conditions. The relic S1 schistosity is deformed by isoclinal to subisoclinal F2 folds showing similar geometry. The F2 folds are characterized by a continuous S2 crenulation cleavage developed under greenschist-facies metamorphism. The parallelism between the A2 axes and the related L2 mineral lineations suggests an interpretation of the F2 folds as sheath folds developed during non-coaxial deformation. The kinematic indicators suggest a top-to-W sense of shear for the D2 phase. The D3 phase is distinguished by asymmetric, parallel F3 folds with a S vergence. Finally, the D4 phase consists of F4 open, gentle folds with high-angle to sub-vertical axial planes. The collected data suggest a complex deformation history, characterized by coupling of strike-slip tectonics and shortening during the retrograde evolution of the blueschist-facies sequences

Gender-specific association of the K121Q Ectonucleotide Pyrophosphatase Phosphodiesterase (ENPP) 1 polymorphism with subcutaneous adiposity in a South African Black population

Purpose: This study aimed to determine whether the ENPP-1 K121Q (rs1044498) polymorphism was associated with adiposity and cardiometabolic disease markers within a South African Black population. Methods: Black participants from the greater Johannesburg–Soweto area in South Africa, for whom metabolic syndrome status, cardiometabolic disease markers, adipokine levels and body fat distribution had already been measured, were genotyped by PCR-RFLP for the presence of the K121Q polymorphism.Results: Within a cohort of 345 Black South Africans, the frequency of the ENPP-1 K121Q C allele was 0.89. In the total cohort, the K121Q polymorphism was not significantly associated with any cardiometabolic disease markers or adipokine levels. However, in the female population the CC genotype was shown to be associated with increased abdominal subcutaneous fat levels (p=0.007). Conclusion: This cohort of Black South Africans had a higher frequency of the C allele when compared to reported data for Asian and Caucasian populations, however this frequency was comparable to other African data. The presence of the rs1044498 polymorphism was not associated with markers of cardiometabolic disease, suggesting that these associations may be population dependent. The gender-specific genotypic association with subcutaneous fat levels is a novel finding requiring further investigation

Habitat availability for amphibians and extinction threat: A global analysis

Aim: Habitat loss and degradation are the factors threatening the largest number of amphibian species. However, quantitative measures of habitat availability only exist for a small subset of them. We evaluated the relationships between habitat availability, extinction risk and drivers of threat for the world's amphibians. We developed deductive habitat suitability models to estimate the extent of suitable habitat and the proportion of suitable habitat (PSH) inside the geographic range of each species, covering species and areas for which little or no high-resolution distribution data are available. Location: Global. Methods: We used information on habitat preferences to develop habitat suitability models at 300-m resolution, by integrating range maps with land cover and elevation. Model performance was assessed by comparing model output with point localities where species were recorded. We then used habitat availability as a surrogate of area of occupancy. Using the IUCN criteria, we identified species having narrow area of occupancy, for which extinction risk is likely underestimated. Results: We developed models for 5363 amphibians. Validation success of models was high (94%), being better for forest specialists and generalists than for open habitat specialists. Generalists had proportionally more habitat than forest or open habitat specialists. The PSH was lower for species having small geographical ranges, currently listed as threatened, and for which habitat loss is recognized as a threat. Differences in habitat availability among biogeographical realms were strong. We identified 61 forest species for which the extinction risk may be higher that currently assessed in the Red List, due to limited extent of suitable habitat. Main conclusions: Habitat models can accurately predict amphibian distribution at fine scale and allow describing biogeographical patterns of habitat availability. The strong relationship between amount of suitable habitat and extinction threat may help the conservation assessment in species for which limited information is currently available

ReptIslands: Mediterranean islands and the distribution of their reptile fauna

Aim: Analyses of biogeographical patterns and macroecology of islands require large datasets reporting the occurrence of species. The Mediterranean region is a biodiversity hotspot, which hosts a large number of reptile species and has been the focus of many studies. Nevertheless, comprehensive inventories describing the features and biodiversity of these environments are lacking. We gathered a dataset summarizing data on reptile distribution on islands of the Mediterranean basin and Macaronesia, also including detailed information on the geographical features. Location: Islands from the Mediterranean Basin, the Atlantic Ocean within the Mediterranean biogeographical region, and Macaronesia (Canary and Savage Islands, Azores, Madeira and Cape Verde). Time period: Present. Taxon: Reptiles (squamates and turtles). Methods: Initially, we developed a geographical database describing islands of the study region, then gathered information on reptile occurrences from 757 bibliographical sources, including atlases, published papers and the grey literature. Through a critical review of these sources, we also obtained information on the status of populations (native, island endemic or non-native) and on the reliability of occurrence data. Results: We obtained basic geographical information from 1875 islands covering the whole study region and with a very broad range of geographical features. We gathered >4150 records of reptile occurrence on islands, referring to 198 taxonomic units (species or species complexes); information on population status was available for 84.9% of records. Data are provided as comma-delimited text files. Main conclusions: The database provides a key resource for biogeographical analyses and can also serve as a backbone for conservation studies. The availability of a large database on island features can also be useful for biogeographers working on other taxonomic groups. Nevertheless, more data are required for some geographical areas, in order to ascertain the status (e.g., native vs. non-native) of many populations and to understand the interplay between natural and human-driven processes

Preference Transitivity and Symbolic Representation in Capuchin Monkeys (Cebus apella)

BACKGROUND: Can non-human animals comprehend and employ symbols? The most convincing empirical evidence comes from language-trained apes, but little is known about this ability in monkeys. Tokens can be regarded as symbols since they are inherently non-valuable objects that acquire an arbitrarily assigned value upon exchange with an experimenter. Recent evidence suggested that capuchin monkeys, which diverged from the human lineage 35 million years ago, can estimate, represent and combine token quantities. A fundamental and open question is whether monkeys can reason about symbols in ways similar to how they reason about real objects. METHODOLOGY/PRINCIPAL FINDINGS: Here we examined this broad question in the context of economic choice behavior. Specifically, we assessed whether, in a symbolic context, capuchins' preferences satisfy transitivity--a fundamental trait of rational decision-making. Given three options A, B and C, transitivity holds true if A > or = B, B > or = C and A > or = C (where > or = indicates preference). In this study, we trained monkeys to exchange three types of tokens for three different foods. We then compared choices monkeys made between different types of tokens with choices monkeys made between the foods. Qualitatively, capuchins' preferences revealed by the way of tokens were similar to those measured with the actual foods. In particular, when choosing between tokens, monkeys displayed strict economic preferences and their choices satisfied transitivity. Quantitatively, however, values measured by the way of tokens differed systematically from those measured with the actual foods. In particular, for any pair of foods, the relative value of the preferred food increased when monkeys chose between the corresponding tokens. CONCLUSIONS/SIGNIFICANCE: These results indicate that indeed capuchins are capable of treating tokens as symbols. However, as they do so, capuchins experience the cognitive burdens imposed by symbolic representation

Differences between microhabitat and broad-scale patterns of niche evolution in terrestrial salamanders

The extent to which closely related species share similar niches remains highly debated. Ecological niches are increasingly analysed by combining distribution records with broad-scale climatic variables, but interactions between species and their environment often occur at fine scales. The idea that macroscale analyses correctly represent fine-scale processes relies on the assumption that average climatic variables are meaningful predictors of processes determining species persistence, but tests of this hypothesis are scarce. We compared broad- and fine-scale (microhabitat) approaches by analyzing the niches of European plethodontid salamanders. Both the microhabitat and the macroecological approaches identified niche differences among species, but the correspondence between micro- and macroecological niches was weak. When exploring niche evolution, the macroecological approach suggested a close relationship between niche and phylogenetic history, but this relationship did not emerge in fine-scale analyses. The apparent pattern of niche evolution emerging in broad-scale analyses likely was the by-product of related species having closely adjacent ranges. The environment actually experienced by most of animals is more heterogeneous than what is apparent from macro-scale predictors, and a better combination between macroecological and fine-grained data may be a key to obtain robust ecological generalizations

A common neural scale for the subjective pleasantness of different primary rewards.

When an economic decision is taken, it is between goals with different values, and the values must be on the same scale. Here, we used functional MRI to search for a brain region that represents the subjective pleasantness of two different rewards on the same neural scale. We found activity in the ventral prefrontal cortex that correlated with the subjective pleasantness of two fundamentally different rewards, taste in the mouth and warmth on the hand. The evidence came from two different investigations, a between-group comparison of two independent fMRI studies, and from a within-subject study. In the latter, we showed that neural activity in the same voxels in the ventral prefrontal cortex correlated with the subjective pleasantness of the different rewards. Moreover, the slope and intercept for the regression lines describing the relationship between activations and subjective pleasantness were highly similar for the different rewards. We also provide evidence that the activations did not simply represent multisensory integration or the salience of the rewards. The findings demonstrate the existence of a specific region in the human brain where neural activity scales with the subjective pleasantness of qualitatively different primary rewards. This suggests a principle of brain processing of importance in reward valuation and decision-making

Handbook for Surveillance and Monitoring of European Habitats. First Edition

The primary objective of this Handbook is to describe the methodology appropriate for coordinating information on habitats in order to obtain statistically robust estimates of their extent and associated changes in biodiversity. Such detailed rules are necessary if surveillance; i.e., recording information at a point in time; is to be repeated subsequently as monitoring, otherwise real changes cannot be separated reliably from background noise. The BioHab procedure will also map all Pan-European classifications, such as EUNIS, where possible, as a basis for their surveillance and monitoring throughout Europe. The basis of the General Habitat Categories is the classification of plant Life Forms produced by the Danish botanist Raunkiaer early in the 20th century. These Life Forms e.g. annuals or trees, transcend species. They are based on the scientific hypothesis that habitat structure is related to the environment. The BioHab General Habitat Categories cover the pan-European region (except Turkey) with 130 GHC¿s derived from 16 Life Forms (LF¿s). They have been field tested in all the environmental zones in Europe. Variation within a General Habitat Category is then expressed by environmental and global qualifiers, which are combinations of soil humidity, nutrient status, acidity and other habitat characteristics. Important additional information is given by adding codes from predefined lists of site and management qualifiers