MasterChem: Cooking 2D-polymers

2D-polymers are still dominated by graphene and closely related materials such as boron nitride, transition metal sulphides and oxides. However, the rational combination of molecules with suitable design is already showing the high potential of chemistry in this new research field. The aim of this feature article is to illustrate, and provide some perspectives, the current state-of-the-art in the field of synthetic 2D-polymers showing different alternatives to prepare this novel type of polymers based on the rational use of chemistry. This review comprises a brief revision of the essential concepts, the strategies of preparation following the two general approaches, bottom-up and top-down, and a revision of the promising seminal properties showed by some of these nanomaterials.Financial support from Spanish MINECO (MAT2013-46753-C2-1-P and MAT2013-46502-C2-2-P). D. R. thanks the Spanish MECD for a FPU gran

Neighborhood models of minority opinion spreading

We study the effect of finite size population in Galam's model [Eur. Phys. J. B 25 (2002) 403] of minority opinion spreading and introduce neighborhood models that account for local spatial effects. For systems of different sizes N, the time to reach consensus is shown to scale as ln N in the original version, while the evolution is much slower in the new neighborhood models. The threshold value of the initial concentration of minority supporters for the defeat of the initial majority, which is independent of N in Galam's model, goes to zero with growing system size in the neighborhood models. This is a consequence of the existence of a critical size for the growth of a local domain of minority supporters

Nonlinear oscillator with parametric colored noise: some analytical results

The asymptotic behavior of a nonlinear oscillator subject to a multiplicative Ornstein-Uhlenbeck noise is investigated. When the dynamics is expressed in terms of energy-angle coordinates, it is observed that the angle is a fast variable as compared to the energy. Thus, an effective stochastic dynamics for the energy can be derived if the angular variable is averaged out. However, the standard elimination procedure, performed earlier for a Gaussian white noise, fails when the noise is colored because of correlations between the noise and the fast angular variable. We develop here a specific averaging scheme that retains these correlations. This allows us to calculate the probability distribution function (P.D.F.) of the system and to derive the behavior of physical observables in the long time limit

Ratchet behavior in nonlinear Klein-Gordon systems with point-like inhomogeneities

We investigate the ratchet dynamics of nonlinear Klein-Gordon kinks in a periodic, asymmetric lattice of point-like inhomogeneities. We explain the underlying rectification mechanism within a collective coordinate framework, which shows that such system behaves as a rocking ratchet for point particles. Careful attention is given to the kink width dynamics and its role in the transport. We also analyze the robustness of our kink rocking ratchet in the presence of noise. We show that the noise activates unidirectional motion in a parameter range where such motion is not observed in the noiseless case. This is subsequently corroborated by the collective variable theory. An explanation for this new phenomenom is given

Resonance induced by repulsive interactions in a model of globally-coupled bistable systems

We show the existence of a competition-induced resonance effect for a generic globally coupled bistable system. In particular, we demonstrate that the response of the macroscopic variable to an external signal is optimal for a particular proportion of repulsive links. Furthermore, we show that a resonance also occurs for other system parameters, like the coupling strength and the number of elements. We relate this resonance to the appearance of a multistable region, and we predict the location of the resonance peaks, by a simple spectral analysis of the Laplacian matrix

Squeezing resulting from a fourth-order interaction in a degenerate parametric amplifier with absorption losses

7 págs.; 8 figs.The squeezing properties of a model of a degenerate parametric amplifier with absorption losses and an added fourth-order nonlinearity have been analyzed. The approach used consists of obtaining the Langevin equation for the optical field from the Heisenberg equation provided that a linearization procedure is valid. The steady states of the deterministic equations have been obtained and their local stability has been analyzed. The stationary covariance matrix has been calculated below and above threshold. Below threshold, a squeezed vacuum state is obtained and the nonlinear effects in the fluctuations have been taken into account by a Gaussian decoupling. In the case above threshold, a phase-squeezed coherent state is obtained and numerical simulations allowed to compute the time interval, depending on the loss parameter, on which the system jumps from one stable state to the other. Finally, the variances numerically determined have been compared with those obtained from the linearized theory and the limits of validity of the linear theory have been analyzed. It has become clear that the nonlinear contribution may perhaps be profitably used for the construction of above-threshold squeezing devices. © 1991 The American Physical Society.Peer Reviewe

Increasing Pediatric Hearing Aid Use: Considerations for Clinical Practice

Purpose: Hearing aid use can be variable for young children, and inconsistent wear time can undermine spoken language development. This study explored the effectiveness of hearing aid data logging (DL) awareness and coaching sessions on increasing hours of hearing aid use. We also collected qualitative data on challenges participants experienced managing hearing aid use. Method: We used a single-subject design that included three conditions, during a 6-week period, in the same order for each participant. Condition A was baseline, Condition B was DL monitoring alone, and Condition C was remote coaching calls plus DL monitoring. Results: Hours of hearing aid use increased for each child from baseline to the end of the study, ranging from 1.19 to 4.4 hr. Mothers reported that the coaching calls were beneficial and helped them identify and problem-solve issues. Conclusions: Parents were able to increase hours of hearing aid use with DL awareness and coaching support. Tele-audiology offers an opportunity to provide parents with more frequent support that can be individualized based on their situation, challenges, and family needs

Self-Pulsating Semiconductor Lasers: Theory and Experiment

We report detailed measurements of the pump-current dependency of the self-pulsating frequency of semiconductor CD lasers. A distinct kink in this dependence is found and explained using rate-equation model. The kink denotes a transition between a region where the self-pulsations are weakly sustained relaxation oscillations and a region where Q-switching takes place. Simulations show that spontaneous emission noise plays a crucial role for the cross-over.Comment: Revtex, 16 pages, 7 figure

Selfsimilar Domain Growth, Localized Structures and Labyrinthine Patterns in Vectorial Kerr Resonators

We study domain growth in a nonlinear optical system useful to explore different scenarios that might occur in systems which do not relax to thermodynamic equilibrium. Domains correspond to equivalent states of different circular polarization of light. We describe three dynamical regimes: a coarsening regime in which dynamical scaling holds with a growth law dictated by curvature effects, a regime in which localized structures form, and a regime in which polarization domain walls are modulationally unstable and the system freezes in a labyrinthine pattern.Comment: 13 pages, 6 figure

Roadmap to cure multiple myeloma

Despite significant advances in the treatment of multiple myeloma which had led to unprecedented rates of response and survival, patients still relapse, and cure remains elusive. We propose in this review a roadmap to achieve the dream of cure for multiple myeloma based on five complementary strategies. First, to increase knowledge about disease pathogenesis with a focus on the biology of circulating tumor cells, responsible for dissemination and extramedullary disease, and minimal residual disease clones who represent the reservoir of clonal evolution and disease recurrence. Second, to consider undetectable measurable residual disease (MRD), defined by high-sensitive techniques, as the new endpoint of therapy. Third, to treat disease causation instead of symptomatology through early detection and intervention. Thereby, by treating high-risk smoldering myeloma patients early, we may not only contribute to delay disease progression into active disease but also to increase the cure rates. Fourth, to use the most active scheme in standard-risk patients if the cure is in the horizon. Fifth, to investigate experimental therapies in newly diagnosed patients with high-risk MM, implementing early rescue intervention strategies with the goal of eradicating all tumor clones, and achieving minimal residual disease negativity