351 research outputs found

    Improving Urban Transportation through the European Experience: The Case of Brasilia, Brazil

    Get PDF

    Cartas do barítono Raimundo Pereira: potencialidades da escrita epistolar como fonte em estudos biográficos

    Get PDF
    Neste estudo propõe-se refletir sobre a escrita epistolar como um documento significativo nos estudos biográficos. Nessa perspectiva, foram mobilizadas quatro cartas escritas pelo cantor lírico Raimundo Pereira: missiva com datada em 06 de julho de 1983, dirigida ao Maestro Reginaldo Carvalho; carta publicada no Jornal do Brasil, coluna Correios, Caderno B Programas, em 27 de fevereiro de 1991; epístola para a mãe, datada de 26 de abril de 1993; e carta divulgada na coluna Opinião do Leitor, Jornal do Brasil, em 16 de outubro de 2000. Além das cartas escritas pelo barítono, também utilizamos uma correspondência sobre o artista, escrita por um leitor e veiculada no caderno B, coluna Cartas, Jornal do Brasil, em 08 de janeiro de 1993 e analisada conforme Mignot (2018). A documentação analisada para além da materialidade documental e conteúdo informativo, considerandou-se, a partir de Rocha (2021), a subjetividade e pessoalidade dos documentos resguardados em arquivos pessoais e familiares. Interrogou-se: quais as potencialidades da fonte epistolar na construção de um estudo biográfico? A análise permitiu reconhecer que as cartas se configuraram em documentos centrais, e situou as correspondências como substanciais para o estudo biográfico sobre barítono no que se refere as viagens, militância e expectativas

    Genetic variability of two populations of Pseudoplatystoma reticulatum from the Upper Paraguay River Basin

    Get PDF
    Catfishes of the genus Pseudoplatystoma are very important species due to both their high commercial value and their ecological role as voracious predators. They undertake lengthy migratory movements during their life-cycle, this including reproductive migration which occurs from October to December in the rainy season. In the present study, seven microsatellite loci were analyzed to access genetic variability in two samples of P. reticulatum from the Upper Paraguay Basin. The loci were highly polymorphic (mean = 7.28). According to all analysis, the two samples of P. reticulatum revealed pronounced genetic differentiation. Fst value was 0.2290, Rst value 0.1067 and AMOVA 22.90% (Fst ) and 10.67% (Rst ), all being highly significant (p < 0.001). The division of the fishes into two groups was confirmed by microsatellite multi-locus Bayesian assignment testing. The results obtained present evidence of genetic structuring in a P. reticulatum population

    Avaliação da toxicidade na superfície ocular após instilação tópica de doadores de óxido nítrico

    Get PDF
    PURPOSE: To evaluate the ocular surface toxicity of two nitric oxide donors in ex vivo and in vivo animal models: S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine (SNAC) in a hydroxypropyl methylcellulose (HPMC) matrix at final concentrations 1.0 and 10.0 mM. METHODS: Ex vivo GSNO and SNAC toxicities were clinically and histologically analyzed using freshly excised pig eyeballs. In vivo experiments were performed with 20 albino rabbits which were randomized into 4 groups (5 animals each): Groups 1 and 2 received instillations of 150 µL of aqueous HPMC solution containing GSNO 1.0 and 10.0 mM, respectively, in one of the eyes; Groups 3 and 4 received instillations of 150 µL of aqueous HPMC solution-containing SNAC 1.0 and 10.0 mM, respectively, in one of the eyes. The contralateral eyes in each group received aqueous HPMC as a control. All animals underwent clinical evaluation on a slit lamp and the eyes were scored according to a modified Draize eye test and were histologically analyzed. RESULTS: Pig eyeballs showed no signs of perforation, erosion, corneal opacity or other gross damage. These findings were confirmed by histological analysis. There was no difference between control and treated rabbit eyes according to the Draize eye test score in all groups (p>0.05). All formulations showed a mean score under 1 and were classified as non-irritating. There was no evidence of tissue toxicity in the histological analysis in all animals. CONCLUSION: Aqueous HPMC solutions containing GSNO and SNAC at concentrations up to 10.0 mM do not induce ocular irritation.OBJETIVO: Avaliar a toxidade na superfície ocular de dois compostos doadores de óxido nítrico em modelos ex vivo e in vivo: S-nitrosoglutationa (GSNO) e S-nitroso-N-acetilcisteína (SNAC), em uma matriz de hidroxipropil metilcelulose (HPMC) nas concentrações finais de 1,0 and 10,0 mM. MÉTODOS: As toxicidades de GSNO e SNAC foram avaliadas clinicamente e histologicamente em modelo ex vivo usando globos oculares porcinos recém excisados. Experimentos in vivo foram realizados com 20 coelhos albinos que foram randomizados em 4 grupos (5 animais em cada): Os grupos 1 e 2 receberam instilações de 150 µL de solução aquosa de HPMC contendo GSNO 1,0 e 10,0 mM, respectivamente, em um dos olhos; Os grupos 3 e 4 receberam instilações de 150 µL de solução aquosa de HPMC contendo SNAC 1,0 and 10,0 mM, respectivamente, em um dos olhos. Os olhos contralaterias em cada grupo receberam solução aquosa de HPMC como controle. Todos os animais foram clinicamente avaliados em lâmpada de fenda e os olhos foram pontuados de acordo com o teste de Draize modificado e analisados histologicamente. RESULTADOS: Os globos oculares porcinos não apresentaram sinais de perfuração, erosão, opacidade da córnea ou outros danos graves. Esses resultados foram confirmados pela análise histológica. Não houve diferença entre os olhos dos coelhos tratados e controles de acordo com a pontuação do teste de Draize em todos os grupos (p>0,05). Todas as formulações apresentaram um escore médio menor do que 1 e foram classificadas como não-irritantes. Não houve evidência de toxicidade tecidual nas análises histológicas em todos os animais. CONCLUSÃO: Soluções aquosas de HPMC contendo GSNO e SNAC em concentrações até 10,0 mM não induzem irritação ocular.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo (UNIFESP) Department of OphthalmologyUniversidade Estadual de Campinas Institute of ChemistryUniversidade Federal de São Paulo (UNIFESP) Department of PathologyUNIFESP, Department of OphthalmologyUNIFESP, Department of PathologySciEL

    Impact of Care Interventions on the Survival of Patients with Cardiac Chest Pain

    Get PDF
    Background: Chest pain is considered the second most frequent complaint among patients seeking emergency services. However, there is limited information in the literature about how the care provided to patients with chest pain, when being attended to in the emergency room, influences their clinical outcomes. Aims: To assess the relationship between care interventions performed on patients with cardiac chest pain and their immediate and late clinical outcomes and to identify which care interventions were essential to survival. Methods: In this retrospective study. We analyzed 153 medical records of patients presenting with chest pain at an emergency service center, São Paulo, Brazil. Participants were divided into two groups: (G1) remained hospitalized for a maximum of 24 h and (G2) remained hospitalized for between 25 h and 30 days. Results: Most of the participants were male 99 (64.7%), with a mean age of 63.2 years. The interventions central venous catheter, non-invasive blood pressure monitoring, pulse oximetry, and monitoring peripheral perfusion were commonly associated with survival at 24 h and 30 days. Advanced cardiovascular life support and basic support life (p = 0.0145; OR = 8053; 95% CI = 1385–46,833), blood transfusion (p &lt; 0.0077; OR = 34,367; 95% CI = 6489–182,106), central venous catheter (p &lt; 0.0001; OR = 7.69: 95% CI 1853–31,905), and monitoring peripheral perfusion (p &lt; 0.0001; OR = 6835; 95% CI 1349–34,634) were independently associated with survival at 30 days by Cox Regression. Conclusions: Even though there have been many technological advances over the past decades, this study demonstrated that immediate and long-term survival depended on interventions received in an emergency room for many patients

    CRITÉRIOS ANALÍTICOS PARA LICENCIAMENTO AMBIENTAL DE ESTAÇÕES DE TRATAMENTO DE ESGOTOS: UMA CONTRIBUIÇÃO A PARTIR DE ESTUDOS DE CASOS NA BACIA HIDROGRÁFICA DO RIO SÃO FRANCISCO

    Get PDF
    As estações de tratamento de esgotos (ETE) têm o seu planejamento, implantação e operação dependentes de apreciação técnica realizada no âmbito do Licenciamento Ambiental, já que são normativamente classificadas como atividades ou empreendimentos potencialmente poluidores. Este artigo propõe dois modelos analíticos, a saber, um referente à Licença Prévia e outro à Licença de Instalação, contendo os elementos de análise utilizados pelos órgãos ambientais durante a apreciação dessas licenças. Ademais, é também apresentada a análise da prática do órgão ambiental do estado da Bahia, por meio de quatro estudos de caso de Licenciamento Ambiental de ETE integrantes de Sistemas de Esgotamento Sanitário localizados na Bacia Hidrográfica do Rio São Francisco. Constatou-se que a prática do órgão ambiental não incorpora os elementos propostos nos modelos. A análise da adequação da ETE ao ambiente local mostrou-se limitada, evidenciando um baixo nível de estudos dos principais impactos associados a essa tipologia. Observou-se, também, a falta de fundamentação para a conclusão de deferimento ou não das licenças, bem como das medidas propostas para minimização dos impactos negativos. A apreciação realizada se mostra insuficiente para que a função primordial do Licenciamento Ambiental seja, de fato, cumprida. Como medida de aprimoramento, os resultados da pesquisa sugerem uma padronização mínima dos elementos técnicos a serem analisados durante o processo de licenciamento dessas unidades

    O Uso do Gênero Textual WebQuest como Incentivo para a Aprendizagem Colaborativa dos Alunos de um Curso Técnico Profissionalizante

    Get PDF
    The present study was developed through applied research in the People Management discipline of a state educational institution, located in the northern region of the state of Paraná. The question that guides the research is: the use of the textual genre WebQuest encourages the collaborative learning of students of the Professional Technical Course in Administration? In line with this issue, it was proposed to carry out a task, that students should access the WebQuest entitled "Entrepreneurial Profile" and perform the available activity. This research is considered, as its objective, as exploratory; as for the procedures, such as survey and quali-quantitative approach. Sixteen students participated in the study and data collection occurred in the first semester of 2019. According to the students' answers, it was found that 75% feel more satisfied in carrying out activities in a collaborative way, therefore, it was identified that the use of the textual genre WebQuest proves to be productive for scientific learning in an educational environment in process collaborative work. Keywords: WebQuest. Textual genre. Collaborative learning. O presente estudo foi desenvolvido por meio de uma pesquisa aplicada na disciplina Gestão de Pessoas de uma instituição estadual de ensino localizada na região norte do estado do Paraná. A questão norteadora da pesquisa é: a utilização do gênero textual WebQuest incentiva a aprendizagem colaborativa dos alunos do Curso Técnico Profissionalizante em Administração? Em consonância com essa problemática, foi proposta a realização de uma tarefa em que os alunos deveriam acessar a WebQuest intitulada “Perfil Empreendedor” e realizar a atividade disponível. Esta pesquisa é considerada, quanto ao seu objetivo, como exploratória; quanto aos procedimentos, como de levantamento e de abordagem quali-quantitativa. Participaram do estudo 16 alunos, e a coleta de dados ocorreu no primeiro semestre de 2019. De acordo com as respostas dos alunos, constatou-se que 75% se sentem mais satisfeitos em realizar atividades de forma colaborativa. Portanto, identificou-se que o uso do gênero textual WebQuest se revela produtivo para a aprendizagem científica em ambiente educacional em processo de trabalho colaborativo. Palavras-chave: WebQuest. Gênero Textual. Aprendizagem colaborativa

    Chemodectoma in a Dog

    Get PDF
    Background: The chemodectoma is a rare neoplasm that originates from chemoreceptors located mainly in the aortic body, and carotid body and sinus, and responsible for detecting variations in blood pH, oxygen pressure and carbon dioxide. Dogs of brachiocephalic breeds and aged between 7 and 15 years have greater propensity. A neoplasm involves infiltrative growth in the vessels at the heart base, which leads to Congestive Heart Failure (CHF). The definitive diagnosis is performed by histopathological and/or immunohistochemical examination. The aim was to report a case of chemiodectoma in a dog, showed the disease clinical characteristics.Case: A 13-year-old male undefined breed dog was examinated in the medical clinic of small animal of Veterinary Hospital, Federal Rural University of Pernambuco (UFRPE) with respiratory effort, hyporexia, and edema in face, cervical, ventral thorax and thoracic limbs, with thirty days evoluted. About physical examination, we observed cachexia, orthopneic position, cyanosis and edema with a positive Godet sign, as well as 8% dehydration degree. Thoracic auscultation presented mixed dyspnea and muffled heart sounds. Chest radiography detected an radiopacity increase in pulmonary section and metastatic neoplastic process associated with pleural and pericardial effusion. Fluid therapy with lactated ringer and posterior thoracentesis in the right hemithorax region was performed for greater respiratory comfort for the patient. Hematological count and biochemical profiles stated normochromic normocytic anemia, relative and absolute lymphopenia, thrombocytopenia, as well as increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The patient died after 12 hours when was submitted to necroscopic examination and histopathological evaluation. An infiltrative tumor of cardiac base was observed invading the light of the right atrium, obstructing the venous return, as well as a large thrombus located in the left ventricle and diffuse nodules in the lungs. Hydrothorax and hydroperitoneum were observed with serous fluid, with hepatic, renal and brain congestion, and duodenum hemorrhage. Histologically, the tumor was characterized as a chemodectoma with pulmonary metastasis.Discussion: Cardiac tumors are uncommon for canine population. A study sampled 729,265 dogs with observed incidence reaching 0.19%. The most common type is hemangiosarcoma with 69%, followed by chemiodectoma and lymphoma. Authors describe predisposed brachycephalic breeds such as Boxer, Boston Terrier and French Bulldog. In our case, the patient had elongated snout and undefined breed. Deregulation of chemoreceptors, which detect changes in pH and partial oxygen and carbon dioxide pressures, can result in hyperpnea and dyspnoea. Edema represents a deficit in venous return from the cranial and cervical regions, with consequent increase in hydrostatic pressure and liquid leakage into the thoracic cavity and subcutaneous tissue, thus inferring the Caudal Vena Cava Syndrome (CVCS). Tumors from the cardiac base, integrated with the large arteries insertion and adjacent to the atria, can cause pericardial effusion observed in this case. Chemodectomas are described as essentially benign tumors with low metastatic potential. In this case, pulmonary metastasis was detected. Surgical treatment is recommended when feasible. In this case, the patient had late veterinary care, in addition to the contraindication for surgery by the lung metastasis presence

    Clinical epidemiological profile and the main diagnostic labels nursing to hospitalized patients with stroke in a large hospital in the south of the Legal Amazônia region

    Get PDF
    Introduction: Cerebrovascular Accident (CVA) is a disease that leaves to the patient some important neurological deficits interfering in maintaining the health and quality of life, therefore it becomes essential identify the epidemiological clinical profile of stroke patients with order to develop nursing actions in a systematic way. Objective: The objectives were identify and analyze the epidemiological clinical profile of patients admitted with a stroke diagnosis in the Intensive Care Unit (ICU) of a large hospital and propose nursing diagnoses labels. Material and Methods: This is a descriptive, cross-sectional and retrospective study with a quantitative approach, the sample was 73 (100%) records of patients with a diagnosis of stroke admitted to the ICU. Results: The most of patients were female 52.1% (38) and 69% (51) of the total sample studied lived in the urban area. The Ischemic Stroke achieved significant prevalence of 63% (46) compared to 32.9% hemorrhagic stroke (24), and 4.1% (3) of the patients were diagnosed with both types of stroke. The analysis found that 87.7% (64) of the patients had hypertension, 30.2% (22) of the patients had diabetes mellitus. Clinical manifestations and consequences presented by the most prevalent patients were 38.4% (28) for hemiplegia, motor aphasia 31.5 % (23) and 21.6% (16) developed memory loss. Conclusion: It was concluded that most patients were female and lived in the urban area with a mean age of 69.1 years. The main proposed nursing diagnoses labels were impaired physical mobility, impaired swallowing, imbalanced nutrition: less than body requirements, and the profile found shows the importance of the multidisciplinary team performance, enabling the creation and implementation of strategies to improvements in care to stroke patients

    Estratégia como prática: um estudo em empresas incubadas de base tecnológica

    Get PDF
    O presente artigo resulta de um estudo realizado em uma incubadora de base tecnológica localizada no Estado do Paraná objetivando analisar como os processos de formação de estratégias organizacionais, a partir de seu entendimento como prática social, se configuram em empresas incubadas e determinam os processos de inovação nesse contexto. Discute-se, a partir da filosofia do processo, como os processos de construção de estratégias organizacionais são articulados em relação à dinâmica social no qual os empreendedores estão imersos e formam as práticas em torno dos processos de inovação organizacional. Para tanto utilizou-se de uma abordagem qualitativa com entrevistas semiestruturadas como instrumento de coleta de dados. As análises das entrevistaqs foram construídas com base na técnica de análise de conteúdo. As categorias de análise foram construídas tendo por base a emergência e recorrência de alguns aspectos sobre o processo de construção das estratégias organizacionais, sendo eles: planejamento, tomada de decisão, flexibilidade da tomada de decisão, iniciativa individual e relacionamento com o mercado. A partir das análises dessas categorias pode-se perceber que o processo de estratégia nas empresas incubadas emerge segundo a concepção da estratégia como prática, sendo as estratégias formuladas de maneira menos formal e mais relacionadas ao tipo emergente.   
    corecore