Analysis of Electrical Porcelain Insulators from Local Clays

This paper focused on the chemical analysis of electrical porcelain insulators based on local clays. Test samples were made by conducting some chemical composition test using the Atomic Assumption Spectrophotometer (AAS). The clay samples were also tested for linear shrinkage and apparent porosity. Based on the results obtained, the linear shrinkage values recorded range from 7.29% to 14.29% for Iva Valley formulations, 5.14% to 14.71% for Nawfija and 7.74% to 10.29% for Ekwulobia. It was observed that linear shrinkage decreases as the content of non-plastic materials increases and increases as clay content increases. Iva Valley formulation recorded porosity values ranging from 8.84% to 20.80%. For Nawfija formulation, porosity values range from 10.81% to 17.30% while Ekwulobia formulations gave porosity values ranging from 9.52% to 16.82. Porcelain insulators that constitute the above results were found to have requisite properties that make them suitable for domestic production of porcelains insulators from the clay samples studied

MEAT QUALITY CHARACTERISTICS OF IMPROVED INDIGENOUS CHICKENS (FUNAAB-ALPHA) FED TURMERIC (Curcuma longa) OR CLOVE (Syzygium aromaticum) AS FEED ADDITIVES

The experiment was conducted to investigate meat quality of improved indigenous chickens (FUNAAB alpha) fed diet containing turmeric (Curcuma longa) and clove (Syzigium aromaticum) powders. One hundred and thirty-five (135) mixed sexed day-old improved indigenous FUNAAB alpha chicks were brooded collectively for two weeks, and assigned into three (3) treatment groups. Each treatment was replicated three times, consisting of fifteen (15) birds. Feed and water were provided ad-libitum through the duration of experiment. The control group was fed the basal diet at starter and  finisher phases (T1), while the other groups were fed clove (Syzygium aromaticum) powder at 3 g/kg (T2) and turmeric (Curcuma longa) (T3) powder at 4 g/kg respectively as additives.   Data obtained were subjected to a One – Way Analysis of Variance in a Completely Randomised Design. Muscle obtained after evisceration was subjected to quality analysis. Proximate composition of meat obtained from chickens fed the basal diet had the highest (p<0.05) moisture content value of 75.45% compared to other treatments. Water absorptive capacity and cook loss of meat obtained from chickens fed 4 g/kg dietary turmeric showed (p<0.05) values of 3% and 16.4% respectively. Meat sensory properties analysed revealed (p<0.05) score in groups fed 3g/kg and 4 g/kg clove and turmeric powders respectively, for tenderness (6.14) and overall acceptability (7.19). Meanwhile (p<0.05) lipoprotein profile was observed in group fed 4 g/kg turmeric powder. Inclusion, turmeric and clove had beneficial effects on FUNAAB Alpha. &nbsp

Peak Expiratory Flow Rate in Normal Hausa-Fulani Children and Adolescents of Northern Nigeria

Background: Peak expiratory flow rate (PEFR) is a useful parameter for assessing respiratory function in health and disease. However there are few studies reporting normal values of this parameter in Northern Nigeria in general and the North western zone in particular. Also prediction formulae for predicting PEFR from anthropometric parameters are not available for this population. The present study was therefore designed to measure Peak expiratory flow rate (PEFR) in normal Hausa-Fulani children and adolescents in Sokoto and to derive prediction formulae for this population. Methods: Apparently healthy boys (n=376) and girls (n=240) aged between 6 and 18 years were randomly selected and their height, weight and chest circumference determined. PEFR was measured at ambient temperature and pressure saturated with water vapour (ATPS) in the erect position. Regression analyses were carried out on the relationship between PEFR and each anthropometric parameter and prediction formulae with the least standard error of estimates chosen. Data obtained in this study were also subjected to prediction formulae derived from Nigerian populations elsewhere. Results: PEFR (L/min) was significantly (P<0.001) higher in boys (382.5 \ub1 118.3) than in girls (332.6 \ub1 88.3). It correlated positively and significantly with age, height, weight and chest circumference in both sexes. The prediction formulae derived from the present data in boys and girls respectively are: PEFR (L/min) = 85.83 + 8.25 x weight (kg) (\ub1 3.15) and PEFR (L/min) = 3.67 + 28.15 x age (years) (\ub1 3.51). The predicted PEFR values obtained using earlier formulae were generally lower than the observed values. Conclusion: PEFR has been obtained in normal healthy Hausa-Fulani children and adolescents in Sokoto and prediction formulae derived for use in this population. The results of this study suggest that the usefulness of prediction formulae may be limited to the ethnic group or locality from which they were derived.Fond : Le d\ue9bit expiratoire maximal (DEM) est un param\ue8tre utile pour \ue9valuer la fonction respiratoire dans la sant\ue9 et la maladie. Cependant, il y a peu d'\ue9tudes indiquant des valeurs normales de ce param\ue8tre au nord du Nig\ue9ria en g\ue9n\ue9ral et la zone occidentale du nord en particulier. En outre les formules de pr\ue9vision pour pr\ue9voir le DEM des param\ue8tres anthropom\ue9triques ne sont pas disponibles pour cette population. La pr\ue9sente \ue9tude a \ue9t\ue9 donc con\ue7ue pour mesurer le d\ue9bit expiratoire maximal (DEM) dans les enfants et les adolescents normaux de hausa-Fulani-Fulani \ue0 Sokoto et pour d\ue9river des formules de pr\ue9vision \ue0 cette population. M\ue9thodes : Les gar\ue7ons apparent en bonne sant\ue9 (n=376) et les filles (n=240) \ue2g\ue9s entre 6 et 18 ans ont \ue9t\ue9 al\ue9atoirement choisis et leur circonf\ue9rence de taille, de poids et de coffre ont \ue9t\ue9 d\ue9termin\ue9es. Le DEM a \ue9t\ue9 mesur\ue9 \ue0 la temp\ue9rature ambiante et \ue0 la pression satur\ue9es avec la vapeur d'eau (TAPS) en position droite. Des analyses de r\ue9gression ont \ue9t\ue9 effectu\ue9es sur le rapport entre le DEM et chaque param\ue8tre anthropom\ue9trique et formules de pr\ue9vision avec la moindre erreur type des \ue9valuations choisies. Des donn\ue9es obtenues dans cette \ue9tude ont \ue9t\ue9 \ue9galement soumises aux formules de pr\ue9vision d\ue9riv\ue9es des populations nig\ue9rianes ailleurs. R\ue9sultats : Le DEM (L/min) \ue9tait de mani\ue8re significative (P<0.001) plus haut dans les gar\ue7ons (382,5 \ub1 118,3) que dans les filles (332,6 \ub1 88,3). Il s'est corr\ue9l\ue9 positivment et de mani\ue8re significative avec l'\ue2ge, la taille, et la circonf\ue9rence de poids et de coffre dans les deux sexes. Les formules de pr\ue9vision d\ue9riv\ue9es des donn\ue9es actuelles dans les gar\ue7ons et dans les filles respectivement sont : DEM (L/min) = 85,83 + 8,25 x poid (kilogramme) (\ub1 3,15) et DEM (L/min) = 3,67 + 28,15 x \ue2ge (ann\ue9es) (\ub1 3,51). Les valeurs du DEM pr\ue9vues obtenues en utilisant des premi\ue8res formules \ue9taient g\ue9n\ue9ralement inf\ue9rieures aux valeurs observ\ue9es. Conclusion : Le DEM a \ue9t\ue9 obtenu dans les enfants et les adolescents de sant\ue9 normale d' Hausa-Fulani \ue0 Sokoto et les formules de pr\ue9vision d\ue9riv\ue9es pour l'usage dans cette population. Les r\ue9sultats de cette \ue9tude sugg\ue8rent que l'utilit\ue9 des formules de pr\ue9vision puisse \ueatre limit\ue9e au groupe ou \ue0 la localit\ue9 ethnique desquels ils ont \ue9t\ue9 d\ue9riv\ue9s

Conference summary report of the 10th Annual General and Scientific Meeting of the Nigerian Society of Neonatal medicine (NISONM) held in Ibadan, Nigeria on 4th -7th July, 2017

The 10th Annual General and Scientific Meeting (AGSM) of the Nigerian Society of Neonatal Medicine (NISONM) took place in Ibadan, South -West Nigeria. The theme of the conference was: Imperatives in neonatal survival initiatives in Nigeria: The current state. The conference addressed a variety of topics relevant to newborn health from eminent speakers from across the globe. The four-day conference included preconference workshops and community mobilization/ health outreach in Lagelu local government area

A novel nonparametric item response theory approach to measuring socioeconomic position: a comparison using household expenditure data from a Vietnam health survey, 2003

BACKGROUND: Measures of household socio-economic position (SEP) are widely used in health research. There exist a number of approaches to their measurement, with Principal Components Analysis (PCA) applied to a basket of household assets being one of the most common. PCA, however, carries a number of assumptions about the distribution of the data which may be untenable, and alternative, non-parametric, approaches may be preferred. Mokken scale analysis is a non-parametric, item response theory approach to scale development which appears never to have been applied to household asset data. A Mokken scale can be used to rank order items (measures of wealth) as well as households. Using data on household asset ownership from a national sample of 4,154 consenting households in the World Health Survey from Vietnam, 2003, we construct two measures of household SEP. Seventeen items asking about assets, and utility and infrastructure use were used. Mokken Scaling and PCA were applied to the data. A single item measure of total household expenditure is used as a point of contrast. RESULTS: An 11 item scale, out of the 17 items, was identified that conformed to the assumptions of a Mokken Scale. All the items in the scale were identified as strong items (Hi > .5). Two PCA measures of SEP were developed as a point of contrast. One PCA measure was developed using all 17 available asset items, the other used the reduced set of 11 items identified in the Mokken scale analaysis. The Mokken Scale measure of SEP and the 17 item PCA measure had a very high correlation (r = .98), and they both correlated moderately with total household expenditure: r = .59 and r = .57 respectively. In contrast the 11 item PCA measure correlated moderately with the Mokken scale (r = .68), and weakly with the total household expenditure (r = .18). CONCLUSION: The Mokken scale measure of household SEP performed at least as well as PCA, and outperformed the PCA measure developed with the 11 items used in the Mokken scale. Unlike PCA, Mokken scaling carries no assumptions about the underlying shape of the distribution of the data, and can be used simultaneous to order household SEP and items. The approach, however, has not been tested with data from other countries and remains an interesting, but under researched approach

Safety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetes

<p>Abstract</p> <p>Background</p> <p>In a previous pooled analysis of 12 double-blind clinical studies that included data on 6,139 patients with type 2 diabetes, treatment with sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, was shown to be generally well tolerated compared with treatment with control agents. As clinical development of sitagliptin continues, additional studies have been completed, and more patients have been exposed to sitagliptin. The purpose of the present analysis is to update the safety and tolerability assessment of sitagliptin by pooling data from 19 double-blind clinical studies.</p> <p>Methods</p> <p>The present analysis included data from 10,246 patients with type 2 diabetes who received either sitagliptin 100 mg/day (N = 5,429; sitagliptin group) or a comparator agent (placebo or an active comparator) (N = 4,817; non-exposed group). The 19 studies from which this pooled population was drawn represent the double-blind, randomized studies that included patients treated with the usual clinical dose of sitagliptin (100 mg/day) for between 12 weeks and 2 years and for which results were available as of July 2009. These 19 studies assessed sitagliptin taken as monotherapy, initial combination therapy with metformin or pioglitazone, or as add-on combination therapy with other antihyperglycemic agents (metformin, pioglitazone, a sulfonylurea ± metformin, insulin ± metformin, or rosiglitazone + metformin). Patients in the non-exposed group were taking placebo, metformin, pioglitazone, a sulfonylurea ± metformin, insulin ± metformin, or rosiglitazone + metformin. The analysis used patient-level data from each study to evaluate between-group differences in the exposure-adjusted incidence rates of adverse events.</p> <p>Results</p> <p>Summary measures of overall adverse events were similar in the sitagliptin and non-exposed groups, except for an increased incidence of drug-related adverse events in the non-exposed group. Incidence rates of specific adverse events were also generally similar between the two groups, except for increased incidence rates of hypoglycemia, related to the greater use of a sulfonylurea, and diarrhea, related to the greater use of metformin, in the non-exposed group and constipation in the sitagliptin group. Treatment with sitagliptin was not associated with an increased risk of major adverse cardiovascular events.</p> <p>Conclusions</p> <p>In this updated pooled safety analysis of data from 10,246 patients with type 2 diabetes, sitagliptin 100 mg/day was generally well tolerated in clinical trials of up to 2 years in duration.</p

Postoperative outcomes in oesophagectomy with trainee involvement

BACKGROUND: The complexity of oesophageal surgery and the significant risk of morbidity necessitates that oesophagectomy is predominantly performed by a consultant surgeon, or a senior trainee under their supervision. The aim of this study was to determine the impact of trainee involvement in oesophagectomy on postoperative outcomes in an international multicentre setting. METHODS: Data from the multicentre Oesophago-Gastric Anastomosis Study Group (OGAA) cohort study were analysed, which comprised prospectively collected data from patients undergoing oesophagectomy for oesophageal cancer between April 2018 and December 2018. Procedures were grouped by the level of trainee involvement, and univariable and multivariable analyses were performed to compare patient outcomes across groups. RESULTS: Of 2232 oesophagectomies from 137 centres in 41 countries, trainees were involved in 29.1 per cent of them (n = 650), performing only the abdominal phase in 230, only the chest and/or neck phases in 130, and all phases in 315 procedures. For procedures with a chest anastomosis, those with trainee involvement had similar 90-day mortality, complication and reoperation rates to consultant-performed oesophagectomies (P = 0.451, P = 0.318, and P = 0.382, respectively), while anastomotic leak rates were significantly lower in the trainee groups (P = 0.030). Procedures with a neck anastomosis had equivalent complication, anastomotic leak, and reoperation rates (P = 0.150, P = 0.430, and P = 0.632, respectively) in trainee-involved versus consultant-performed oesophagectomies, with significantly lower 90-day mortality in the trainee groups (P = 0.005). CONCLUSION: Trainee involvement was not found to be associated with significantly inferior postoperative outcomes for selected patients undergoing oesophagectomy. The results support continued supervised trainee involvement in oesophageal cancer surgery

Grand Challenges in global eye health: a global prioritisation process using Delphi method

Background We undertook a Grand Challenges in Global Eye Health prioritisation exercise to identify the key issues that must be addressed to improve eye health in the context of an ageing population, to eliminate persistent inequities in health-care access, and to mitigate widespread resource limitations. Methods Drawing on methods used in previous Grand Challenges studies, we used a multi-step recruitment strategy to assemble a diverse panel of individuals from a range of disciplines relevant to global eye health from all regions globally to participate in a three-round, online, Delphi-like, prioritisation process to nominate and rank challenges in global eye health. Through this process, we developed both global and regional priority lists. Findings Between Sept 1 and Dec 12, 2019, 470 individuals complete round 1 of the process, of whom 336 completed all three rounds (round 2 between Feb 26 and March 18, 2020, and round 3 between April 2 and April 25, 2020) 156 (46%) of 336 were women, 180 (54%) were men. The proportion of participants who worked in each region ranged from 104 (31%) in sub-Saharan Africa to 21 (6%) in central Europe, eastern Europe, and in central Asia. Of 85 unique challenges identified after round 1, 16 challenges were prioritised at the global level; six focused on detection and treatment of conditions (cataract, refractive error, glaucoma, diabetic retinopathy, services for children and screening for early detection), two focused on addressing shortages in human resource capacity, five on other health service and policy factors (including strengthening policies, integration, health information systems, and budget allocation), and three on improving access to care and promoting equity. Interpretation This list of Grand Challenges serves as a starting point for immediate action by funders to guide investment in research and innovation in eye health. It challenges researchers, clinicians, and policy makers to build collaborations to address specific challenge

Recurrent Nasal Polyp and Pansinus Mucopyocele Associated with Bilateral Blindness: A Case Report

A 39 year old female with 24-month history of recurrent mucoid rhinorhea associated with progressive bilateral nasal blockage, headache, anosmia and bilateral impaired vision is reported. There was a past history of sinus surgery. The neuro-ophthalmic examination revealed left non-axial proptosis and visual acuity of nil light perception in both eyes at 3 meters. CT scan of the paranasal sinuses and brain showed markedly expanded left frontal sinus with sclerotic walls and expanded mixed density lesion in all the sinuses. She had surgery via trans-nasal, external and skull base approaches for effective clearance of the polypoidal masses and drainage of the sinus mucopyocele. Histological examination confirmed chronic inflammatory polyp. She remains stable to date although visual impairment and anosmia remained persistent. Patients with nasal polyposis require frequent follow-up even after surgical treatment for the early detection and management of complications to avoid consequences such as visual loss