Pattern formation in crystal growth under parabolic shear flow

Morphological instability of the solid-liquid interface occuring in a crystal growing from an undercooled thin liquid being bounded on one side by a free surface and flowing down inclined plane is investigated by a linear stability analysis under shear flow. It is found that restoring forces due to gravity and surface tension is important factor for stabilization of the solid-liquid interface on long length scales. This is a new stabilizing effect different from the Gibbs-Thomson effect. A particular long wavelength mode of about 1 cm of wavy pattern observed on the surface of icicles covered with thin layer of flowing water is obtained from the dispersion relation including the effect of flow and restoring forces.Comment: 30 pages, 4 figure

A sharp condition for scattering of the radial 3d cubic nonlinear Schroedinger equation

We consider the problem of identifying sharp criteria under which radial $H^1$ (finite energy) solutions to the focusing 3d cubic nonlinear Schr\"odinger equation (NLS) $i\partial_t u + \Delta u + |u|^2u=0$ scatter, i.e. approach the solution to a linear Schr\"odinger equation as $t\to \pm \infty$. The criteria is expressed in terms of the scale-invariant quantities $\|u_0\|_{L^2}\|\nabla u_0\|_{L^2}$ and $M[u]E[u]$, where $u_0$ denotes the initial data, and $M[u]$ and $E[u]$ denote the (conserved in time) mass and energy of the corresponding solution $u(t)$. The focusing NLS possesses a soliton solution $e^{it}Q(x)$, where $Q$ is the ground-state solution to a nonlinear elliptic equation, and we prove that if $M[u]E[u]<M[Q]E[Q]$ and $\|u_0\|_{L^2}\|\nabla u_0\|_{L^2} < \|Q\|_{L^2}\|\nabla Q\|_{L^2}$, then the solution $u(t)$ is globally well-posed and scatters. This condition is sharp in the sense that the soliton solution $e^{it}Q(x)$, for which equality in these conditions is obtained, is global but does not scatter. We further show that if $M[u]E[u] \|Q\|_{L^2}\|\nabla Q\|_{L^2}$, then the solution blows-up in finite time. The technique employed is parallel to that employed by Kenig-Merle \cite{KM06a} in their study of the energy-critical NLS

Theory and simulation of quantum photovoltaic devices based on the non-equilibrium Green's function formalism

This article reviews the application of the non-equilibrium Green's function formalism to the simulation of novel photovoltaic devices utilizing quantum confinement effects in low dimensional absorber structures. It covers well-known aspects of the fundamental NEGF theory for a system of interacting electrons, photons and phonons with relevance for the simulation of optoelectronic devices and introduces at the same time new approaches to the theoretical description of the elementary processes of photovoltaic device operation, such as photogeneration via coherent excitonic absorption, phonon-mediated indirect optical transitions or non-radiative recombination via defect states. While the description of the theoretical framework is kept as general as possible, two specific prototypical quantum photovoltaic devices, a single quantum well photodiode and a silicon-oxide based superlattice absorber, are used to illustrated the kind of unique insight that numerical simulations based on the theory are able to provide.Comment: 20 pages, 10 figures; invited review pape

Effects of sleep deprivation on neural functioning: an integrative review

Sleep deprivation has a broad variety of effects on human performance and neural functioning that manifest themselves at different levels of description. On a macroscopic level, sleep deprivation mainly affects executive functions, especially in novel tasks. Macroscopic and mesoscopic effects of sleep deprivation on brain activity include reduced cortical responsiveness to incoming stimuli, reflecting reduced attention. On a microscopic level, sleep deprivation is associated with increased levels of adenosine, a neuromodulator that has a general inhibitory effect on neural activity. The inhibition of cholinergic nuclei appears particularly relevant, as the associated decrease in cortical acetylcholine seems to cause effects of sleep deprivation on macroscopic brain activity. In general, however, the relationships between the neural effects of sleep deprivation across observation scales are poorly understood and uncovering these relationships should be a primary target in future research

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362