613 research outputs found
Microwave-assisted synthesis and antibacterial propensity of N0-s-benzylidene-2-propylquinoline- 4-carbohydrazide and N0-((s-1H-pyrrol- 2-yl)methylene)-2-propylquinoline- 4-carbohydrazide motifs
Microwave-assisted approach was utilized as green approach to access a series of 2-pro
pylquinoline-4-carbohydrazide hydrazone derivatives 10a-j of aromatic and heteroaromatic aldehydes
in highly encouraging yields. It involved four steps reaction which was initiated with ring opening
reaction of isatin in a basified environment and subsequent cross-coupling with pentan-2-one to
produce compound 7. Esterification of 7 in acid medium led to the formation of compound 8 which
was reacted with hydrazine hydrate to access 9 which upon microwave-assisted condensed with aromatic
and heteroaromatic aldehydes furnished the targeted compounds 10a-j. The structures of 10aj
were confirmed by physico-chemical, elemental analyses and spectroscopic characterization which
include UV, FT-IR, 1H and 13C NMR as well as DEPT-135. The targeted compounds 10a-j, alongside
with gentamicin clinical standard, were investigated for their antibacterial efficacies using agar
diffusion method. 2-Propyl-N0-(pyridine-3-ylmethylene) quinoline-4-carbohydrazide 10j emerged a
How observations from automatic hail sensors in Switzerland shed light on local hailfall duration and compare with hailpad measurements
Measuring the properties of hailstorms is a difficult task due to the rarity and mainly small spatial extent of the events. Especially, hail observations from ground-based time-recording instruments are scarce. We present the first study of extended field observations made by a network of 80 automatic hail sensors from Switzerland. The main benefits of the sensors are the live recording of the hailstone kinetic energy and the precise timing of the impacts. Its potential limitations include a diameter-dependent dead time, which results in less than 5 % of missed impacts, and the possible recording of impacts that are not due to hail, which can be filtered using a radar reflectivity filter. We assess the robustness of the sensors' measurements by doing a statistical comparison of the sensor observations with hailpad observations, and we show that, despite their different measurement approaches, both devices measure the same hail size distributions. We then use the timing information to measure the local duration of hail events, the cumulative time distribution of impacts, and the time of the largest hailstone during a hail event. We find that 75 % of local hailfalls last just a few minutes (from less than 4.4 min to less than 7.7 min, depending on a parameter to delineate the events) and that 75 % of the impacts occur in less than 3.3 min to less than 4.7 min. This time distribution suggests that most hailstones, including the largest, fall during a first phase of high hailstone density, while a few remaining and smaller hailstones fall in a second low-density phase.</p
Vertical-external-cavity surface-emitting lasers and quantum dot lasers
The use of cavity to manipulate photon emission of quantum dots (QDs) has
been opening unprecedented opportunities for realizing quantum functional
nanophotonic devices and also quantum information devices. In particular, in
the field of semiconductor lasers, QDs were introduced as a superior
alternative to quantum wells to suppress the temperature dependence of the
threshold current in vertical-external-cavity surface-emitting lasers
(VECSELs). In this work, a review of properties and development of
semiconductor VECSEL devices and QD laser devices is given. Based on the
features of VECSEL devices, the main emphasis is put on the recent development
of technological approach on semiconductor QD VECSELs. Then, from the viewpoint
of both single QD nanolaser and cavity quantum electrodynamics (QED), a
single-QD-cavity system resulting from the strong coupling of QD cavity is
presented. A difference of this review from the other existing works on
semiconductor VECSEL devices is that we will cover both the fundamental aspects
and technological approaches of QD VECSEL devices. And lastly, the presented
review here has provided a deep insight into useful guideline for the
development of QD VECSEL technology and future quantum functional nanophotonic
devices and monolithic photonic integrated circuits (MPhICs).Comment: 21 pages, 4 figures. arXiv admin note: text overlap with
arXiv:0904.369
The social affordances of flashpacking: exploring the mobility nexus of travel and communication
The proliferation of digital devices and online social media and networking technologies has altered the backpacking landscape in recent years. Thanks to the ready availability of online communication, travelers are now able to stay in continuous touch with friends, family and other travelers while on the move. This article introduces the practice of ‘flashpacking’ to describe this emerging trend and interrogates the patterns of connection and disconnection that become possible as corporeal travel and social technologies converge. Drawing on the concepts of ‘assemblages’ and ‘affordances’, we outline several aspects of this new sociality: virtual mooring, following, collaborating, and (dis)connecting. The conclusion situates this discussion alongside broader questions about the shifting nature of social life in an increasingly mobile and mediated world and suggests directions for future research at the intersection of tourism and technology
Search for the rare decay
A search for the decay is performed, based on a data sample of 1.0 fb of collisions at collected by the LHCb experiment at the Large Hadron Collider. The observed number of candidates is consistent with the background-only hypothesis, yielding an upper limit of at 95 (90)% confidence level. This limit is a factor of thirty below the previous measurement
Polarimetric radar characteristics of lightning initiation and propagating channels
In this paper we present an analysis of a large dataset of lightning and polarimetric weather radar data collected in the course of a lightning measurement campaign that took place in the summer of 2017 in the area surrounding Säntis, in the northeastern part of Switzerland. For this campaign and for the first time in the Alps, a lightning mapping array (LMA) was deployed. The main objective of the campaign was to study the atmospheric conditions leading to lightning production with a particular focus on the lightning discharges generated due to the presence of the 124¿m tall Säntis telecommunications tower. In this paper we relate LMA very high frequency (VHF) sources data with co-located radar data in order to characterise the main features (location, timing, polarimetric signatures, etc.) of both the flash origin and its propagation path. We provide this type of analysis first for all of the data and then we separate the datasets into intra-cloud and cloud-to-ground flashes (and within this category positive and negative flashes) and also upward lightning. We show that polarimetric weather radar data can be helpful in determining regions where lightning is more likely to occur but that lightning climatology and/or knowledge of the orography and man-made structures is also relevant.Peer ReviewedPostprint (author's final draft
Temperature-stable operation of a quantum dot semiconductor disk laser
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Appl. Phys. Lett. 93, 051104 (2008) and may be found at https://doi.org/10.1063/1.2968137.We demonstrate temperature-independent output characteristics of an optically pumped semiconductor disk laser (SDL) based on quantum dots (QDs) grown in the Stranski-Krastanow regime. The gain structure consists of a stack of 7×3 QD layers, each threefold group being located at an optical antinode position. The SDL emits at 1210nm independent of the pump power density. Threshold and differential efficiency do not dependent on heat sink temperature. Continuous-wave operation close to 300mW output power is achieved using the ground-state transition of the InGaAs QDs.DFG, 43659573, SFB 787: Halbleiter - Nanophotonik: Materialien, Modelle, BauelementeEC/FP6/016769/EU/Nano-Photonics Materials and Technologies for Multicolor High-Power Sources/NATA
Simulation of an SEIR infectious disease model on the dynamic contact network of conference attendees
The spread of infectious diseases crucially depends on the pattern of
contacts among individuals. Knowledge of these patterns is thus essential to
inform models and computational efforts. Few empirical studies are however
available that provide estimates of the number and duration of contacts among
social groups. Moreover, their space and time resolution are limited, so that
data is not explicit at the person-to-person level, and the dynamical aspect of
the contacts is disregarded. Here, we want to assess the role of data-driven
dynamic contact patterns among individuals, and in particular of their temporal
aspects, in shaping the spread of a simulated epidemic in the population.
We consider high resolution data of face-to-face interactions between the
attendees of a conference, obtained from the deployment of an infrastructure
based on Radio Frequency Identification (RFID) devices that assess mutual
face-to-face proximity. The spread of epidemics along these interactions is
simulated through an SEIR model, using both the dynamical network of contacts
defined by the collected data, and two aggregated versions of such network, in
order to assess the role of the data temporal aspects.
We show that, on the timescales considered, an aggregated network taking into
account the daily duration of contacts is a good approximation to the full
resolution network, whereas a homogeneous representation which retains only the
topology of the contact network fails in reproducing the size of the epidemic.
These results have important implications in understanding the level of
detail needed to correctly inform computational models for the study and
management of real epidemics
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