Use of beamforming for detecting an acoustic source inside a cylindrical shell filled with a heavy fluid

International audienceThe acoustic detection of defects or leaks inside a cylindrical shell containing a fluid is of prime importance in the industry, particularly in the nuclear field. This paper examines the beamforming technique which is used to detect and locate the presence of an acoustic monopole inside a cylindrical elastic shell by measuring the external shell vibrations. In order to study the effect of fluid-structure interactions and the distance of the source from the array of sensors, a vibro-acoustic model of the fluid-loaded shell is first considered for numerical experiments. The beamforming technique is then applied to radial velocities of the shell calculated with the model. Different parameters such as the distance between sensors, the radial position of the source, the damping loss factor of the shell, or of the fluid, and modifications of fluid properties can be considered without difficulty. Analysis of thes

Experimental results of passive vibro-acoustic leak detection in SFR steam generator mock-up

International audience# N° 1121 Experimental results of passive vibro-acoustic leak detection in SFR steam generator mock-up 1 Abstract— Regarding to GEN 4 context, it is necessary to fulfil the high safety standards for sodium fast reactors (SFR), particularly against water-sodium reaction which may occur in the steam generator units (SGU) in case of leak. This reaction can cause severe damages in the component in a short time. Detecting such a leak by visual in-sodium inspection is impossible because of sodium opacity. Hydrogen detection is then used but the time response of this method can be high in certain operating conditions. Active and passive acoustic leak detection methods were studied before SUPERPHENIX plant shutdown in 1997 to detect a water-into-sodium leak with a short time response. In the context of the new R&D studies for SFR, an innovative passive vibro-acoustic method is developed in the framework of a Ph.D. thesis to match with GEN 4 safety requirements. The method consists in assuming that a small leak emits spherical acoustic waves in a broadband frequency domain, which propagate in the liquid sodium and excite the SGU cylindrical shell. These spatially coherent waves are supposed to be buried by a spatially incoherent background noise. The radial velocities of the shell is measured by an array of accelerometers positioned on the external envelop of the SGU and a beamforming treatment is applied to increase the signal-to-noise ratio (SNR) and to detect and localize the acoustic source. Previous numerical experiments were achieved and promising results were obtained. In this paper, experimental results of the proposed passive vibro-acoustic leak detection are presented. The experiment consists in a cylindrical water-filled steel pipe representing a model of SGU shell without tube bundle. A hydrophone emitting an acoustic signal is used to simulate an acoustic monopole. Spatially uncorrelated noise or water-flow induced shell vibrations are considered as the background noise. The beamforming method is applied to vibration signals measured by a linear array of accelerometers on the shell. Satisfying results are obtained regarding to detection and localization of the source smothered by the background noise. This research was carried in the framework of the LabEx CeLyA ("Centre Lyonnais d'Acoustique", ANR-10-LABX-60) by the LVA/ INSA de Lyon, in collaboration with AREVA and the CEA (Commissariat à l'Energie Atomique et aux Energies Alternatives) within the framework of a co-financing partnership. The authors are grateful for the interest and financial support received from these two entities. J. Moriot and O. Gastaldi are with DEN/STPA

Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues

Background: Since fall 2019, SARS-CoV-2 spread world-wide, causing a major pandemic with estimated ~ 220 million subjects affected as of September 2021. Severe COVID-19 is associated with multiple organ failure, particularly of lung and kidney, but also grave neuropsychiatric manifestations. Overall mortality reaches > 2%. Vaccine development has thrived in thus far unreached dimensions and will be one prerequisite to terminate the pandemic. Despite intensive research, however, few treatment options for modifying COVID-19 course/outcome have emerged since the pandemic outbreak. Additionally, the substantial threat of serious downstream sequelae, called ‘long COVID’ and ‘neuroCOVID’, becomes increasingly evident. Main body of the abstract: Among candidates that were suggested but did not yet receive appropriate funding for clinical trials is recombinant human erythropoietin. Based on accumulating experimental and clinical evidence, erythropoietin is expected to (1) improve respiration/organ function, (2) counteract overshooting inflammation, (3) act sustainably neuroprotective/neuroregenerative. Recent counterintuitive findings of decreased serum erythropoietin levels in severe COVID-19 not only support a relative deficiency of erythropoietin in this condition, which can be therapeutically addressed, but also made us coin the term ‘hypoxia paradox’. As we review here, this paradox is likely due to uncoupling of physiological hypoxia signaling circuits, mediated by detrimental gene products of SARS-CoV-2 or unfavorable host responses, including microRNAs or dysfunctional mitochondria. Substitution of erythropoietin might overcome this ‘hypoxia paradox’ caused by deranged signaling and improve survival/functional status of COVID-19 patients and their long-term outcome. As supporting hints, embedded in this review, we present 4 male patients with severe COVID-19 and unfavorable prognosis, including predicted high lethality, who all profoundly improved upon treatment which included erythropoietin analogues. Short conclusion: Substitution of EPO may—among other beneficial EPO effects in severe COVID-19—circumvent downstream consequences of the ‘hypoxia paradox’. A double-blind, placebo-controlled, randomized clinical trial for proof-of-concept is warrante

Probing the dynamics of quasicrystal growth using synchrotron live imaging

The dynamics of quasicrystal growth remains an unsolved problem in condensed matter. By means of synchrotron live imaging, facetted growth proceeding by the tangential motion of ledges at the solid-melt interface is clearly evidenced all along the solidification of icosahedral AlPdMn quasicrystals. The effect of interface kinetics is significant so that nucleation and free growth of new facetted grains occur in the melt when the solidification rate is increased. The evolution of these grains is explained in details, which reveals the crucial role of aluminum rejection, both in the poisoning of grain growth and driving fluid flow

Supervivencia y perdurabilidad del Código Civil

Fil: Alterini, Atilio Aníbal. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil. Buenos Aires, ArgentinaFil: López del Carril, Nelson Julio. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil I. Buenos Aires, ArgentinaFil: Greco, Roberto Ernesto. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil II. Buenos Aires, ArgentinaFil: Gastaldi, José María. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil III. Buenos Aires, ArgentinaFil: Russomanno, Mario César. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Romano. Buenos Aires, ArgentinaFil: Maffia, Jorge O. Universidad Nacional de la Plata. Facultad de Ciencias Jurídicas y Sociales. La Plata, ArgentinaFil: Belluscio, Augusto César. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil V. Buenos Aires, Argentin

Status and overview of development of the Silicon Pixel Detector for the PHENIX experiment at the BNL RHIC

We have developed a silicon pixel detector to enhance the physics capabilities of the PHENIX experiment. This detector, consisting of two layers of sensors, will be installed around the beam pipe at the collision point and covers a pseudo-rapidity of | \eta | < 1.2 and an azimuth angle of | \phi | ~ 2{\pi}. The detector uses 200 um thick silicon sensors and readout chips developed for the ALICE experiment. In order to meet the PHENIX DAQ readout requirements, it is necessary to read out 4 readout chips in parallel. The physics goals of PHENIX require that radiation thickness of the detector be minimized. To meet these criteria, the detector has been designed and developed. In this paper, we report the current status of the development, especially the development of the low-mass readout bus and the front-end readout electronics.Comment: 9 pages, 8 figures and 1 table in DOCX (Word 2007); PIXEL 2008 workshop proceedings, will be published in the Proceedings Section of JINST(Journal of Instrumentation

Non-filamentary (VMCO) memory : a two- and three-dimensional study on switching and failure modes

In this work, for the first time, a set of two-and three-dimensional (3D) analysis techniques are combined to clarify the nature of resistive switching (RS) in state-of-the-art TiO2-based vacancy modulated conductive oxide (VMCO) memory. (1) A non-filamentary switching mechanism is observed. (2) The role of oxygen incorporation and motion in the TiO2 is demonstrated. (3) The oxygen profile inside scaled cells is measured and a RS-model based on the modulation of oxygen inside the stack is proposed. In addition, we perform the tomographic analysis of fully-fabricated devices with Scalpel SPM, thus probing in 3D the entire stack and the contribution of TiO2 grain boundaries (GBs) to the switching operations. Finally, devices failed by breakdown (BD) during cycling are characterized, identifying the formation of parasitic filaments as root-cause of the failure

Effect of cashew gum-carboxymethylcellulose edible coatings in extending the shelf-life of fresh and cut guavas.

Cashew gum (CG) and carboxymethylcellulose (CMC) based formulations have been evaluated as protective edible coatings on intact and cut red guavas. Samples were coated by dipping in aqueous mixtures of 1% CG and 1% plasticizer (glycerol) for CMC additions of 1 and 2% wt. The fruit was stored at ambient conditions (25?28 C, 76.0 12.4% RH), and loss of mass, color of pulp and peel, and texture were assessed. Magnetic Resonance Imaging (MRI) was used to visualize the internal structure decay of the intact fruits. Both coatings resulted in a reduction of mass loss, preserving firmness and delaying skin color changes. When comparing after 12 day storage, the mass loss in cut coated samples (CG plus 2% wt of CMC) was 38.5% inferior than that measure to uncoated references. At large, both coating formulations reduced water loss and changes in color of the cut surfaces. MRI analysis showed that tissue decay took place mainly near the peel or around the peduncle region between 8 and 12 days of storage at room temperature