Serie web documental como estrategia de promoción para el centro arqueológico de pinturas rupestres de Faical, San Ignacio, Cajamarca

La presente investigación titulada “Serie web documental como estrategia de promoción para el centro arqueológico de pinturas rupestres de Faical, San Ignacio, Cajamarca” pretende reconocer los atributos y debilidades de un sitio milenario través de una propuesta audiovisual. Para su realización se planteó realizar un matriz FODA sobre el centro arqueológico de pinturas rupestres de Faical, elaborar un arco narrativo que explore los puntos importantes de la historia en cinco capítulos y redactar una escaleta del piloto de la serie web de género documental. Para su desarrollo se aplicaron como instrumentos entrevistas semiestructuradas a especialistas en turismo y cine y la observación directa para identificar puntos resaltantes del centro arqueológico. Los resultados mostraron que una serie web documental es efectiva para promocionar un recurso turístico, puesto que despierta interés en el espectador por conocer lo que ve en pantalla

Análisis de rendimiento de algoritmos de reconocimiento de placas de números de vehículos desarrollado mediante la transformación de ondas discretas y la correlación de imagen digital

Objective: To develop two algorithms to evaluate through the comparison the performance of the Discrete Wavelet Transform (DWT) and Digital Image Correlation (DIC) techniques for the recognition of patterns, and more specifically the automatic recognition of license plates. Results y Conclusions: It can be concluded that one algorithm outperforms the other depending on the test performed; it is imperative to conclude that the most optimal algorithm for the recognition of vehicle registration using the DWT in conjunction with the DIC is that in which the recognition with the HOG detector is performed as an FBM technique; because although the algorithm that uses the normalized cross-correlation has the best performance in terms of time processing.Objetivo: Desarrollar dos algoritmos a fin de evaluar el rendimiento de las técnicas de Transformada Wavelet Discreta (DWT) y Correlación Digital de Imágenes (DIC) para el reconocimiento de patrones, y más específicamente el reconocimiento automático de matrículas, a través de la comparación. Resultados y conclusiones: Se puede concluir que un algoritmo supera al otro dependiendo de la prueba realizada; de este modo, el algoritmo más óptimo para el reconocimiento de la matrícula del vehículo utilizando, el DWT en conjunto con el DIC, es aquel en el que se realiza el reconocimiento con el detector HOG como técnica de FBM, aunque el algoritmo que utiliza la correlación cruzada normalizada tiene el mejor rendimiento en términos de procesamiento de tiempo

Implementación del sistema Sarlaft en los agentes de seguridad social en Salud

En el artículo de investigación que presentamos a continuación, se analizan los impactos que la implementación del sistema de administración del riesgo de lavado de activos conlleva para los agentes del sistema general de seguridad social en salud, especialmente las empresas sociales del estado que prestan servicios de salud, de conformidad con la Ley 100 de 1993. La implementación de dicho sistema se solicitó por la Superintendencia Nacional de Salud a los agentes del sistema general de seguridad social en salud y es de cumplimiento obligatorio. En efecto, es importante conocer los obstáculos que tendrá la implementación de dicho sistema en este tipo de entidades, ya que no se tenía conciencia en el sector salud de que podría ser utilizado para este fin

Molecular systematics of the genus Acidithiobacillus:insights into the phylogenetic structure and diversification of the taxon

The acidithiobacilli are sulfur-oxidizing acidophilic bacteria that thrive in both natural and anthropogenic low pH environments. They contribute to processes that lead to the generation of acid rock drainage in several different geoclimatic contexts, and their properties have long been harnessed for the biotechnological processing of minerals. Presently, the genus is composed of seven validated species, described between 1922 and 2015: Acidithiobacillus thiooxidans, A. ferrooxidans, A. albertensis, A. caldus, A. ferrivorans, A. ferridurans, and A. ferriphilus. However, a large number of Acidithiobacillus strains and sequence clones have been obtained from a variety of ecological niches over the years, and many isolates are thought to vary in phenotypic properties and cognate genetic traits. Moreover, many isolates remain unclassified and several conflicting specific assignments muddle the picture from an evolutionary standpoint. Here we revise the phylogenetic relationships within this species complex and determine the phylogenetic species boundaries using three different typing approaches with varying degrees of resolution: 16S rRNA gene-based ribotyping, oligotyping, and multi-locus sequencing analysis (MLSA). To this end, the 580 16S rRNA gene sequences affiliated to the Acidithiobacillus spp. were collected from public and private databases and subjected to a comprehensive phylogenetic analysis. Oligotyping was used to profile high-entropy nucleotide positions and resolve meaningful differences between closely related strains at the 16S rRNA gene level. Due to its greater discriminatory power, MLSA was used as a proxy for genome-wide divergence in a smaller but representative set of strains. Results obtained indicate that there is still considerable unexplored diversity within this genus. At least six new lineages or phylotypes, supported by the different methods used herein, are evident within the Acidithiobacillus species complex. Although the diagnostic characteristics of these subgroups of strains are as yet unresolved, correlations to specific metadata hint to the mechanisms behind econiche-driven divergence of some of the species/phylotypes identified. The emerging phylogenetic structure for the genus outlined in this study can be used to guide isolate selection for future population genomics and evolutionary studies in this important acidophile model

Draft genome sequence of the type strain of the sulfur-oxidizing acidophile, Acidithiobacillus albertensis (DSM 14366)

Abstract Acidithiobacillus albertensis is an extremely acidophilic, mesophilic, obligatory autotrophic sulfur-oxidizer, with potential importance in the bioleaching of sulfidic metal ores, first described in the 1980s. Here we present the draft genome sequence of Acidithiobacillus albertensis DSM 14366T, thereby both filling a long-standing gap in the genomics of the acidithiobacilli, and providing further insight into the understanding of the biology of the non iron-oxidizing members of the Acidithiobacillus genus. The assembled genome is 3,1 Mb, and contains 47 tRNAs, tmRNA gene and 2 rRNA operons, along with 3149 protein-coding predicted genes. The Whole Genome Shotgun project was deposited in DDBJ/EMBL/GenBank under the accession MOAD00000000

Ready To Drink

El presente trabajo de investigación se ha elaborado con la finalidad de implementar una nueva idea de negocio innovadora en la ciudad de Lima Metropolitana. Básicamente nuestro trabajo de investigación contiene algunos pasos previos antes de dar a conocer nuestro producto en el mercado. Por ello, se realizó una investigación de mercado con el objetivo de tener un mayor conocimiento acerca de cómo se mueve el mercado Limeño y sobre los productos y servicios que el ciudadano limeño necesita en la actualidad. Los resultados obtenidos después haber hechos entrevistas, encuestas y amplias charlas con personas que formen parte de nuestro público objetivo, nos indicaron que: aquellas personas que acostumbran salir a reuniones con sus amigos o van a discotecas, buscan adquirir bebidas alcohólicas que sean de calidad y de buen sabor, también optan por adquirir bebidas que tengan precios aceptables de acuerdo a la ocasión. Es por ello, que después de todas esta investigaciones e hipótesis realizadas, nuestro equipo de trabajo optó por concretar este nuevo emprendimiento de una bebida con Pisco a base de frutas exóticas (Aguaymanto y Mora), pero con una presentación diferente al resto de productos que forman parte de nuestra competencia, nuestra bebida tendrá una presentación de 5 litros, con envases de vidrio, ya que buscamos tener un compromiso con el cuidado del medio ambiente y de nuestros consumidores, además nuestra bebida tendrá una preparación artesanal. Asimismo, nuestras ventas se realizarán a través de nuestras páginas de Facebook e Instagram.This research work has been prepared with the purpose of implementing a new innovative business idea in the city of Metropolitan Lima. Basically, our research work contains some preliminary steps before making our product known in the market. For this reason, a market research was carried out with the aim of having a better knowledge about how the Limean market moves and about the products and services that the Limean citizen needs today. The results obtained after having conducted interviews, surveys and extensive talks with people who are part of our target audience, indicated that: Those people who usually go out to mee- tings with their friends or go to discos, seek to purchase alcoholic beverages that are of quality and good taste, they also choose to purchase drinks that have acceptable prices according to the occasion. That´s why, after all these investigations and hypotheses carried out, our work team chose to specify this new undertaking of a Pisco drink based on exotic fruits (Aguaymanto and Mora), but with a different presentation than the rest of the products that They are part of our competition, our drink will have a presentation of 5 liters, with glass containers, since we seek to have a commitment to caring for the environment and our consumers, in addition our drink will have a handmade preparation. Likewise, our sales will be made through our Facebook and Instagram pages.Trabajo de investigació

Domestication of Local Microbial Consortia for Efficient Recovery of Gold Through Top-Down Selection in Airlift Bioreactors

Extreme acidophiles play central roles in the geochemical cycling of diverse elements in low pH environments. This has been harnessed in biotechnologies such as biomining, where microorganisms facilitate the recovery of economically important metals such as gold. By generating both extreme acidity and a chemical oxidant (ferric iron) many species of prokaryotes that thrive in low pH environments not only catalyze mineral dissolution but also trigger both community and individual level adaptive changes. These changes vary in extent and direction depending on the ore mineralogy, water availability and local climate. The use of indigenous versus introduced microbial consortia in biomining practices is still a matter of debate. Yet, indigenous microbial consortia colonizing sulfidic ores that have been domesticated, i.e., selected for their ability to survive under specific polyextreme conditions, are claimed to outperform un-adapted foreign consortia. Despite this, little is known on the domestication of acidic microbial communities and the changes elicited in their members. In this study, high resolution targeted metagenomic techniques were used to analyze the changes occurring in the community structure of local microbial consortia acclimated to growing under extreme acidic conditions and adapted to endure the conditions imposed by the target mineral during biooxidation of a gold concentrate in an airlift reactor over a period of 2 years. The results indicated that operative conditions evolving through biooxidation of the mineral concentrate exerted strong selective pressures that, early on, purge biodiversity in favor of a few Acidithiobacillus spp. over other iron oxidizing acidophiles. Metagenomic analysis of the domesticated consortium present at the end of the adaptation experiment enabled reconstruction of the RVS1-MAG, a novel representative of Acidithiobacillus ferrooxidans from the Andacollo gold mineral district. Comparative genomic analysis performed with this genome draft revealed a net enrichment of gene functions related to heavy metal transport and stress management that are likely to play a significant role in adaptation and survival to adverse conditions experienced by these acidophiles during growth in presence of gold concentrates

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

New insights into the genetic etiology of Alzheimer's disease and related dementias

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

XVI International Congress of Control Electronics and Telecommunications: "Techno-scientific considerations for a post-pandemic world intensive in knowledge, innovation and sustainable local development"

Este título, sugestivo por los impactos durante la situación de la Covid 19 en el mundo, y que en Colombia lastimosamente han sido muy críticos, permiten asumir la obligada superación de tensiones sociales, políticas, y económicas; pero sobre todo científicas y tecnológicas. Inicialmente, esto supone la existencia de una capacidad de la sociedad colombiana por recuperar su estado inicial después de que haya cesado la perturbación a la que fue sometida por la catastrófica pandemia, y superar ese anterior estado de cosas ya que se encontraban -y aún se encuentran- muchos problemas locales mal resueltos, medianamente resueltos, y muchos sin resolver: es decir, habrá que rediseñar y fortalecer una probada resiliencia social existente - producto del prolongado conflicto social colombiano superado parcialmente por un proceso de paz exitoso - desde la tecnociencia local; como lo indicaba Markus Brunnermeier - economista alemán y catedrático de economía de la Universidad de Princeton- en su libro The Resilient Society…La cuestión no es preveerlo todo sino poder reaccionar…aprender a recuperarse rápido.This title, suggestive of the impacts during the Covid 19 situation in the world, and which have unfortunately been very critical in Colombia, allows us to assume the obligatory overcoming of social, political, and economic tensions; but above all scientific and technological. Initially, this supposes the existence of a capacity of Colombian society to recover its initial state after the disturbance to which it was subjected by the catastrophic pandemic has ceased, and to overcome that previous state of affairs since it was found -and still is find - many local problems poorly resolved, moderately resolved, and many unresolved: that is, an existing social resilience test will have to be redesigned and strengthened - product of the prolonged Colombian social conflict partially overcome by a successful peace process - from local technoscience; As Markus Brunnermeier - German economist and professor of economics at Princeton University - indicates in his book The Resilient Society...The question is not to foresee everything but to be able to react...learn to recover quickly.Bogot