752 research outputs found

    Feedback Control of Flight Speed to Reduce Unmanned Aerial System Noise

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    The aim of this initial study is to incorporate an acoustic metric into the flight control system of an unmanned aerial vehicle. This could be used to mitigate the noise impact of unmanned aerial systems operating near residential communities. To incorporate an acoustic metric into a pre-existing flight control system, two things are required: a source noise model, and an acoustic controller. An acoustic model was developed based on Gutin's work to estimate propeller noise. The flight control system was augmented with a controller to reduce propeller noise using feedback control of the commanded flight speed until an acoustic target was met. This control approach focuses on modifying flight speed only, with no perturbation to the trajectory. Multiple flight simulations were performed and the results showed that integrating an acoustic metric into the flight control system of an unmanned aerial system is possible

    Neonatal bloodstream infections in a Ghanaian Tertiary Hospital:Are the current antibiotic recommendations adequate?

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    Abstract Background Diagnosis of bloodstream infections (BSI) in neonates is usually difficult due to minimal symptoms at presentation; thus early empirical therapy guided by local antibiotic susceptibility profile is necessary to improve therapeutic outcomes. Methods A review of neonatal blood cultures submitted to the microbiology department of the Korle-Bu Teaching Hospital was conducted from January 2010 through December 2013. We assessed the prevalence of bacteria and fungi involved in BSI and the susceptibility coverage of recommended empiric antibiotics by Ghana Standard Treatment guidelines and the WHO recommendations for managing neonatal sepsis. The national and WHO treatment guidelines recommend either ampicillin plus gentamicin or ampicillin plus cefotaxime for empiric treatment of neonatal BSI. The WHO recommendations also include cloxacillin plus gentamicin. We described the resistance profile over a 28-day neonatal period using multivariable logistic regression analysis with linear or restricted cubic splines. Results A total of 8,025 neonatal blood culture reports were reviewed over the four-year period. Total blood culture positivity was 21.9 %. Gram positive organisms accounted for most positive cultures, with coagulase negative staphylococci (CoNS) being the most frequently isolated pathogen in early onset infections (EOS) (59.1 %) and late onset infections (LOS) (52.8 %). Susceptibility coverage of early onset bacterial isolates were 20.7 % to ampicillin plus cefotaxime, 32.2 % to the combination of ampicillin and gentamicin, and 71.7 % to cloxacillin plus gentamicin. For LOS, coverage was 24.6 % to ampicillin plus cefotaxime, 36.2 % to the combination ampicillin and gentamicin and 63.6 % to cloxacillin plus gentamicin. Cloxacillin plus gentamicin remained the most active regimen for EOS and LOS after exclusion of BSI caused by CoNS. For this regimen, the adjusted odds of resistance decreased between 12-34 % per day from birth to day 3 followed by the slowest rate of resistance increase, compared to the other antibiotic regimen, thereafter until day 28. The trend in resistance remained generally unchanged after excluding data from CoNS. Multidrug resistant isolates were significantly (p-value <0.001) higher in LOS (62.4 %, n = 555/886) than in EOS (37.3 %, n = 331/886). Conclusions There is low antibiotic susceptibility coverage for organisms causing neonatal bloodstream infections in Korle-Bu Teaching Hospital when the current national and WHO recommended empiric antibiotics were assessed. A continuous surveillance of neonatal BSI is required to guide hospital and national antibiotic treatment guidelines for neonatal sepsis

    Sampling of Students’ Reflections on the Symposium

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    Following the Global Voices Symposium, some faculty members asked their students to reflect on what they had heard. The following are a sampling of those reflections.https://ecommons.udayton.edu/global_voices_5/1010/thumbnail.jp

    Physicians' knowledge, attitudes, and perceptions concerning antibiotic resistance:a survey in a Ghanaian tertiary care hospital

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    Abstract Background Understanding the knowledge, attitudes and practices of physicians towards antibiotic resistance is key to developing interventions aimed at behavior change. The survey aimed to investigate physicians’ knowledge and attitudes towards antibiotic resistance in a tertiary-care hospital setting in Ghana. Methods We conducted a cross-sectional respondent-driven survey using a 40-item, anonymous, voluntary, traditional paper-and-pencil self-administered questionnaire among 159 physicians at Korle-Bu Teaching Hospital. Single and multi-factor analysis were conducted to assess the study objectives. Results The survey was completed by 159 of 200 physicians (response rate of 79.5%). Of physicians, 30.1% (47/156) perceived antibiotic resistance as very important global problem, 18.5% (29/157) perceived it as very important national problem and only 8.9% (14/157) thought it as a very important problem in their hospital. Methicillin resistant Staphylococcus aureus was the most known about antibiotic resistant bacteria of public health importance followed by extended-spectrum beta-lactamase-producing Enterobacteriaceae, carbapenem resistant Enterobacteriaceae (CRE) and vancomycin resistant enterococci (VRE). In multiple logistic regression analysis, senior physicians were nearly 3 times more likely to know about CRE than junior physicians. The odds of knowing about VRE increased over 4.5 times from being a junior to becoming senior physician. Among junior physicians, age had no associated effect on their knowledge of VRE or CRE. Conclusions Physicians in this survey showed variable knowledge and perceptions on antibiotic resistance. Introducing educational programs on antibiotic resistance would be a useful intervention and should focus on junior physicians

    Nodal dynamics, not degree distributions, determine the structural controllability of complex networks

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    Structural controllability has been proposed as an analytical framework for making predictions regarding the control of complex networks across myriad disciplines in the physical and life sciences (Liu et al., Nature:473(7346):167-173, 2011). Although the integration of control theory and network analysis is important, we argue that the application of the structural controllability framework to most if not all real-world networks leads to the conclusion that a single control input, applied to the power dominating set (PDS), is all that is needed for structural controllability. This result is consistent with the well-known fact that controllability and its dual observability are generic properties of systems. We argue that more important than issues of structural controllability are the questions of whether a system is almost uncontrollable, whether it is almost unobservable, and whether it possesses almost pole-zero cancellations.Comment: 1 Figures, 6 page

    The Mobile CubeSat Command and Control (MC3) Ground Station Network: An Overview and Look Ahead

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    The Mobile CubeSat Command and Control (MC3) ground station network is a Department of Defense (DoD)-led effort to build common-use infrastructure supporting communications and mission operations of small satellites for a wide range of US government organizations, contractors, universities, and foreign partners. The network consists of low-cost ground station terminals fielded at participating institutions, providing operators bent-pipe access to their satellites from any location with an internet connection. MC3 currently consists of eight active stations, and three international collaborators. One of the most important aspects of the ground station network has been the diverse community of small satellite users that have come together to share capabilities of mutual interest. This paper describes the MC3 network and presents an overview of cost-effective future capabilities that will benefit researchers flying experiments on small satellites. Key capabilities include the Satellite Agile Transmit and Receive Network (SATRN) software, flexible software-defined radio architectures, fast-track radio licensing, expanded frequency support, and integration into secure cloud-based infrastructure. The paper also highlights some of the research undertaken at the Naval Postgraduate School (NPS) which utilizes the MC3 network and the satellites it operates as a testbed for advanced concepts. Research topics include optimization of constellation operations, predictive modeling of pass quality, and representative communications experiments flown on high altitude balloons and high power rockets

    Thank You to Our 2018 Peer Reviewers

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    On behalf of the journal, AGU, and the scientific community, the Editors would like to sincerely thank those who reviewed manuscripts for Geophysical Research Letters in 2018. The hours reading and commenting on manuscripts not only improves the manuscripts but also increases the scientific rigor of future research in the field. We particularly appreciate the timely reviews, in light of the demands imposed by the rapid review process at Geophysical Research Letters. With the revival of the “major revisions” decisions, we appreciate the reviewers’ efforts on multiple versions of some manuscripts. Many of those listed below went beyond and reviewed three or more manuscripts for our journal, and those are indicated in italics. In total, 4,484 referees contributed to 7,557 individual reviews in journal. Thank you again. We look forward to the coming year of exciting advances in the field and communicating those advances to our community and to the broader public.Key PointIn total, 4,484 referees contributed to 7,557 individual reviews in journalPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152982/1/grl59194.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/152982/2/grl59194_am.pd
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