LESÕES ANATOMOPATOLÓGICAS PRESENTES NA INFECÇÃO POR DIOCTOPHYMA RENALE (GOEZE, 1782) EM CÃES DOMÉSTICOS (CANIS FAMILIARIS,) LINNAEUS, 1758

Os autores descrevem as lesões anatomopatológicas de onze casos de parasitismo por Dioctophyma renale (Goeze, 1782), na cidade de Curitiba - PR, Brasil, constatados em necrópsias e achados clínicos em 1960 cães, no período de 1979 a 2004. Anatomopathologic lesions found in Dioctophyma renale (Goeze, 1782) infections in domestic dogs (Canis familiaris, LINNAEUS, 1758 Abstract The authors describe the anatomopathologic lesions of eleven cases of parasitism by Dioctophyma renale (Goeze, 1782), in Curitiba (PR, Brazil), found among 1960 necropsies carried out between 1979 and 2004 in dogs

Near-intrinsic energy resolution for 30-662 keV gamma rays in a high pressure xenon electroluminescent TPC

We present the design, data and results from the NEXT prototype for Double Beta and Dark Matter (NEXT-DBDM) detector, a high-pressure gaseous natural xenon electroluminescent time projection chamber (TPC) that was built at the Lawrence Berkeley National Laboratory. It is a prototype of the planned NEXT-100 136Xe neutrino-less double beta decay (0νββ) experiment with the main objectives of demonstrating near-intrinsic energy resolution at energies up to 662 keV and of optimizing the NEXT-100 detector design and operating parameters. Energy resolutions of ∼1% FWHM for 662 keV gamma rays were obtained at 10 and 15 atm and ∼5% FWHM for 30 keV fluorescence xenon X-rays. These results demonstrate that 0.5% FWHM resolutions for the 2,459 keV hypothetical neutrino-less double beta decay peak are realizable. This energy resolution is a factor 7 to 20 better than that of the current leading 0νββ experiments using liquid xenon and thus represents a significant advancement. We present also first results from a track imaging system consisting of 64 silicon photo-multipliers recently installed in NEXT-DBDM that, along with the excellent energy resolution, demonstrates the key functionalities required for the NEXT-100 0νββ search

Ionization and scintillation of nuclear recoils in gaseous xenon

Abstract Ionization and scintillation produced by nuclear recoils in gaseous xenon at approximately 14 bar have been simultaneously observed in an electroluminescent time projection chamber. Neutrons from radioisotope α-Be neutron sources were used to induce xenon nuclear recoils, and the observed recoil spectra were compared to a detailed Monte Carlo employing estimated ionization and scintillation yields for nuclear recoils. The ability to discriminate between electronic and nuclear recoils using the ratio of ionization to primary scintillation is demonstrated. These results encourage further investigation on the use of xenon in the gas phase as a detector medium in dark matter direct detection experiments.This work was supported by the following agencies and institutions: the Director, Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy, and the National Energy Research Scientific Computing Center (NERSC), supported by the Office of Science of the U.S. Department of Energy, both under Contract no. DE-AC02-05CH11231; the European Research Council under the Advanced Grant 339787-NEXT; the Ministerio de Economia y Competitividad of Spain under Grants CONSOLIDER-Ingenio 2010 C5D2008-0037 (CUP), FPA2009-13697-004-04, FPA2009-13697-C04-01, FIS2012-37947-C04-01, FIS2012-37947-C04-02, FIS2012-37947-C04-03, and FIS2012-37947-C04-04; and the Portuguese FCT and FEDER through the program COMPETE, Projects PTDC/FIS/103860/2008 and PTDC/FIS/112272/2009. J. Renner acknowledges the support of a Department of Energy National Nuclear Security Administration Stewardship Science Graduate Fellowship, grant number DE-FC52-08NA28752.Renner, J.; Gehman, VM.; Goldschmidt, A.; Matis, HS.; Miller, T.; Nakajima, Y.; Nygren, D.... (2015). Ionization and scintillation of nuclear recoils in gaseous xenon. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 793:62-74. https://doi.org/10.1016/j.nima.2015.04.057S627479

Comparación de distintas estrategias para la predicción de muerte a corto plazo en el paciente anciano infectado

Objective. The aim of this study was to determine the utility of a post hoc lactate added to SIRS and qSOFA score to predict 30-day mortality in older non-severely dependent patients attended for infection in the Emergency Department (ED). Methods. We performed an analytical, observational, prospective cohort study including patients of 75 years of age or older, without severe functional dependence, attended for an infectious disease in 69 Spanish ED for 2-day three seasonal periods. Demographic, clinical and analytical data were collected. The primary outcome was 30-day mortality after the index event. Results. We included 739 patients with a mean age of 84.9 (SD 6.0) years; 375 (50.7%) were women. Ninety-one (12.3%) died within 30 days. The AUC was 0.637 (IC 95% 0.587-0.688; p= 2 and 0.698 (IC 95% 0.635- 0.761; p= 2. Comparing receiver operating characteristic (ROC) there was a better accuracy of qSOFA vs SIRS (p=0.041). Both scales improve the prognosis accuracy with lactate inclusion. The AUC was 0.705 (IC95% 0.652-0.758; p<0.001) for SIRS plus lactate and 0.755 (IC95% 0.696-0.814; p<0.001) for qSOFA plus lactate, showing a trend to statistical significance for the second strategy (p=0.0727). Charlson index not added prognosis accuracy to SIRS (p=0.2269) or qSOFA (p=0.2573). Conclusions. Lactate added to SIRS and qSOFA score improve the accuracy of SIRS and qSOFA to predict short-term mortality in older non-severely dependent patients attended for infection. There is not effect in adding Charlson index

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time, and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space. While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes, vast areas of the tropics remain understudied. In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity, but it remains among the least known forests in America and is often underrepresented in biodiversity databases. To worsen this situation, human-induced modifications may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge, it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

LESÕES ANATOMOPATOLÓGICAS PRESENTES NA INFECÇÃO POR DIOCTOPHYMA RENALE (GOEZE, 1782) EM CÃES DOMÉSTICOS (CANIS FAMILIARIS,) LINNAEUS, 1758

Os autores descrevem as lesões anatomopatológicas de onze casos de parasitismo por Dioctophyma renale (Goeze, 1782), na cidade de Curitiba - PR, Brasil, constatados em necrópsias e achados clínicos em 1960 cães, no período de 1979 a 2004. Anatomopathologic lesions found in Dioctophyma renale (Goeze, 1782) infections in domestic dogs (Canis familiaris, LINNAEUS, 1758 Abstract The authors describe the anatomopathologic lesions of eleven cases of parasitism by Dioctophyma renale (Goeze, 1782), in Curitiba (PR, Brazil), found among 1960 necropsies carried out between 1979 and 2004 in dogs