Extragalactic Zeeman Detections in OH Megamasers

We have measured the Zeeman splitting of OH megamaser emission at 1667 MHz from five (ultra)luminous infrared galaxies ([U]LIRGs) using the 305 m Arecibo telescope and the 100 m Green Bank Telescope. Five of eight targeted galaxies show significant Zeeman-splitting detections, with 14 individual masing components detected and line-of-sight magnetic field strengths ranging from ~0.5-18 mG. The detected field strengths are similar to those measured in Galactic OH masers, suggesting that the local process of massive star formation occurs under similar conditions in (U)LIRGs and the Galaxy, in spite of the vastly different large-scale environments. Our measured field strengths are also similar to magnetic field strengths in (U)LIRGs inferred from synchrotron observations, implying that milligauss magnetic fields likely pervade most phases of the interstellar medium in (U)LIRGs. These results provide a promising new tool for probing the astrophysics of distant galaxies.Comment: 32 pages, 14 figures, 8 tables. Accepted for publication in The Astrophysical Journal v680n2, June 20, 2008; corrected 2 typo

Configuration of the high‐latitude thermosphere neutral circulation for IMF B y negative and positive

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94946/1/grl2864.pd

Centaurus A: multiple outbursts or bursting bubble?

We present new radio observations of the brighter region of the northern lobe (the Northern Middle Lobe, NML) of Centaurus A obtained at 20 cm with the Australia Telescope Compact Array. The angular resolutions are ~50 and ~130 arcsec, therefore much higher than for the previously available radio images of this region. The most interesting feature detected is a large-scale jet that connects the inner radio lobe and the NML and that is imaged for the first time. The NML itself appears as diffuse emission with a relatively bright ridge on the eastern side. The radio morphology of Centaurus A and, in particular, its NML could be the result of a precessing jet that has undergone a strong interaction with the environment at least in the northern side. The very big drop in intensity between the inner jet and the large-scale jet can be explained with a sequence of bursts of activity at different epochs in the life of the source. Alternatively (or additionally) a ``bursting bubble'' model is proposed which could also explain the good collimation of the large-scale jet. In this model, the plasma accumulated in the inner lobe would be able to ``burst'' out only through one nozzle that would be the region where the large-scale jet forms. From the comparison between the radio emission and the regions of ionized gas we find that the inner optical filament falls about 2 arcmin (~2 kpc) away from the large-scale radio jet. Thus, this filament does not seem to have experienced a direct interaction with the radio plasma. The outer filaments appear to be, in projection, closer to the radio emission, arguing for a direct interaction with the radio jet. However, also in this case a more complicated interaction than assumed so far has to be occuring.Comment: To appear in MNRAS; 11 pages, LateX, 7 figures. Fig 1 is available at http://www.ira.bo.cnr.it/~rmorgant/Centaurus

Pattern and process in Amazon tree turnover, 1976-2001

Previous work has shown that tree turnover, tree biomass and large liana densities have increased in mature tropical forest plots in the late twentieth century. These results point to a concerted shift in forest ecological processes that may already be having significant impacts on terrestrial carbon stocks, fluxes and biodiversity. However, the findings have proved controversial, partly because a rather limited number of permanent plots have been monitored for rather short periods. The aim of this paper is to characterize regional-scale patterns of 'tree turnover' (the rate with which trees die and recruit into a population) by using improved datasets now available for Amazonia that span the past 25 years. Specifically, we assess whether concerted changes in turnover are occurring, and if so whether they are general throughout the Amazon or restricted to one region or environmental zone. In addition, we ask whether they are driven by changes in recruitment, mortality or both. We find that: (i) trees 10 cm or more in diameter recruit and die twice as fast on the richer soils of southern and western Amazonia than on the poorer soils of eastern and central Amazonia; (ii) turnover rates have increased throughout Amazonia over the past two decades; (iii) mortality and recruitment rates have both increased significantly in every region and environmental zone, with the exception of mortality in eastern Amazonia; (iv) recruitment rates have consistently exceeded mortality rates; (v) absolute increases in recruitment and mortality rates are greatest in western Amazonian sites; and (vi) mortality appears to be lagging recruitment at regional scales. These spatial patterns and temporal trends are not caused by obvious artefacts in the data or the analyses. The trends cannot be directly driven by a mortality driver (such as increased drought or fragmentation-related death) because the biomass in these forests has simultaneously increased. Our findings therefore indicate that long-acting and widespread environmental changes are stimulating the growth and productivity of Amazon forests

Insecticide resistance and the future of malaria control in Zambia.

BACKGROUND: In line with the Global trend to improve malaria control efforts a major campaign of insecticide treated net distribution was initiated in 1999 and indoor residual spraying with DDT or pyrethroids was reintroduced in 2000 in Zambia. In 2006, these efforts were strengthened by the President's Malaria Initiative. This manuscript reports on the monitoring and evaluation of these activities and the potential impact of emerging insecticide resistance on disease transmission. METHODS: Mosquitoes were captured daily through a series of 108 window exit traps located at 18 sentinel sites. Specimens were identified to species and analyzed for sporozoites. Adult Anopheles mosquitoes were collected resting indoors and larva collected in breeding sites were reared to F1 and F0 generations in the lab and tested for insecticide resistance following the standard WHO susceptibility assay protocol. Annual cross sectional household parasite surveys were carried out to monitor the impact of the control programme on prevalence of Plasmodium falciparum in children aged 1 to 14 years. RESULTS: A total of 619 Anopheles gambiae s.l. and 228 Anopheles funestus s.l. were captured from window exit traps throughout the period, of which 203 were An. gambiae malaria vectors and 14 An. funestus s.s.. In 2010 resistance to DDT and the pyrethroids deltamethrin, lambda-cyhalothrin and permethrin was detected in both An. gambiae s.s. and An. funestus s.s.. No sporozoites were detected in either species. Prevalence of P. falciparum in the sentinel sites remained below 10% throughout the study period. CONCLUSION: Both An. gambiae s.s. and An. funestus s.s. were controlled effectively with the ITN and IRS programme in Zambia, maintaining a reduced disease transmission and burden. However, the discovery of DDT and pyrethroid resistance in the country threatens the sustainability of the vector control programme

Impact of Community-Based Larviciding on the Prevalence of Malaria Infection in Dar es Salaam, Tanzania.

The use of larval source management is not prioritized by contemporary malaria control programs in sub-Saharan Africa despite historical success. Larviciding, in particular, could be effective in urban areas where transmission is focal and accessibility to Anopheles breeding habitats is generally easier than in rural settings. The objective of this study is to assess the effectiveness of a community-based microbial larviciding intervention to reduce the prevalence of malaria infection in Dar es Salaam, United Republic of Tanzania. Larviciding was implemented in 3 out of 15 targeted wards of Dar es Salaam in 2006 after two years of baseline data collection. This intervention was subsequently scaled up to 9 wards a year later, and to all 15 targeted wards in 2008. Continuous randomized cluster sampling of malaria prevalence and socio-demographic characteristics was carried out during 6 survey rounds (2004-2008), which included both cross-sectional and longitudinal data (N = 64,537). Bayesian random effects logistic regression models were used to quantify the effect of the intervention on malaria prevalence at the individual level. Effect size estimates suggest a significant protective effect of the larviciding intervention. After adjustment for confounders, the odds of individuals living in areas treated with larviciding being infected with malaria were 21% lower (Odds Ratio = 0.79; 95% Credible Intervals: 0.66-0.93) than those who lived in areas not treated. The larviciding intervention was most effective during dry seasons and had synergistic effects with other protective measures such as use of insecticide-treated bed nets and house proofing (i.e., complete ceiling or window screens). A large-scale community-based larviciding intervention significantly reduced the prevalence of malaria infection in urban Dar es Salaam

The westward thermospheric jet-stream of the evening auroral oval

One of the most consistent and often dramatic interactions between the high latitude ionosphere and the thermosphere occurs in the vicinity of the auroral oval in the afternoon and evening period. Ionospheric ions, convected sunward by the influence of the magnetospheric electric field, create a sunward jet-stream in the thermosphere, where wind speeds of up to 1 km s-1 can occur. This jet-stream is nearly always present in the middle and upper thermosphere (above 200 km altitude), even during periods of very low geomagnetic activity. However, the magnitude of the winds in the jet-stream, as well as its location and range in latitude, each depend on geomagnetic activity. On two occasions, jet-streams of extreme magnitude have been studied using simultaneous ground-based and satellite observations, probing both the latitudinal structure and the local time dependence. The observations have then been evaluated with the aid of simulations using a global, three-dimensional, time-dependent model of thermospheric dynamics including the effects of magnetospheric convection and particle precipitation. The extreme events, where sunward winds of above 800 ms-1 are generated at relatively low geomagnetic latitudes (60-70[deg]) require a greatly expanded auroral oval and large cross-polar cap electric field ( ~ 150 kV). These in turn are generated by a persistent strong Interplanetary Magnetic Field, with a large southward component. Global indices such as Kp are a relatively poor indicator of the magnitude and extent of the jet-stream winds.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25724/1/0000281.pd

Inhibition of urokinase plasminogen activator with a novel enzyme inhibitor, wxc-340, ameliorates endotoxin and surgery-accelerated growth of murine metastases

The urokinase plasminogen activator (u-PA) is intimately associated with tumour invasion and metastases. Surgery facilitates accelerated metastatic tumour growth in murine models, a phenomenon related to elevated perioperative bacterial lipopolysaccaride (LPS) and inflammatory cytokine levels. The objectives of the study were to examine the role of u-PA in cytokine-enhanced tumour cell invasion in vitro and surgery-induced accelerated metastatic tumour growth in vivo and to assess the potential benefit of a novel selective u-PA inhibitor WXC-340 in this setting. CT-26 murine colorectal carcinoma cells were stimulated with LPS, tumour necrosis factor α (TNF-α) and interleukin 6 (IL-6). Cell supernatant u-PA expression and activity were determined using a colorimetric assay and Western blot analysis, respectively. Baseline and cytokine-stimulated in vitro invasion were assessed using ECmatrix invasion chambers. Two established murine models of accelerated metastatic tumour growth were used to investigate the consequences of u-PA inhibition on postoperative metastatic tumour burden. The effect of u-PA inhibition in vitro and in vivo was examined using the novel selective u-PA inhibitor, WXC-340. Proinflammatory cytokine stimulation significantly enhanced in vitro u-PA expression, activity and extracellular matrix invasion by approximately 50% compared to controls (P<0.05). This was abrogated by WXC-340. In vivo WXC-340 almost completely ameliorated both LPS- and surgery-induced, metastatic tumour growth compared to controls (P>0.05). In conclusion, u-PA cascade is actively involved in cytokine-mediated enhanced tumour cell invasion and LPS and surgery-induced metastatic tumour growth. Perioperative u-PA inhibition with WXC-340 may represent a novel therapeutic paradigm

An approach to emotion recognition in single-channel EEG signals: a mother child interaction

In this work, we perform a first approach to emotion recognition from EEG single channel signals extracted in four (4) mother-child dyads experiment in developmental psychology -- Single channel EEG signals are analyzed and processed using several window sizes by performing a statistical analysis over features in the time and frequency domains -- Finally, a neural network obtained an average accuracy rate of 99% of classification in two emotional states such as happiness and sadness20th Argentinean Bioengineering Society Congress, SABI 2015 (XX Congreso Argentino de Bioingeniería y IX Jornadas de Ingeniería Clínica)28–30 October 2015, San Nicolás de los Arroyos, Argentin