621 research outputs found
Use of flight interception traps of Malaise type and attractive traps for social wasps record (Vespidae: Polistinae)
The literature provides different methodologies for sampling social
wasps, including, flight intercept trap type Malaise and Attractive
trap, however, there is no consensus on its use. In this respect, the
aim of this study was to evaluate the best use of Malaise traps and
Attractive trap in biodiversity work of social wasps, and generate a
collection protocol for the use of these traps. The study was conducted
in the Parque Estadual do Rio Doce, located in the east of the state
of Minas Gerais, in the years 2000, 2001, 2002 and 2004 and in the
Botanical Garden of the Federal University of Juiz de Fora, located in
the southeastern state of Minas Gerais, in years 2011, 2012 and 2013.
15 species were collected using Malaise traps, and, 26 species of social
wasps were collected using Attractive traps. Although the negative
aspects of both traps, complementary methodologies surveys varying
social wasps are useful and it is recommended to choose for using in
accordance with the logistical field
Impedance measurements and simulations on the TCT and TDI LHC collimators
The LHC collimation system is a critical element for
the safe operation of the LHC machine and it is subject
to continuous performance monitoring, hardware upgrade
and optimization. In this work we will address the impact
on impedance of the upgrades performed on the injection
protection target dump (TDI), where the absorber material
has been changed to mitigate the device heating observed
in machine operation, and on selected secondary (TCS) and
tertiary (TCT) collimators, where beam position monitors
(BPM) have been embedded for faster jaw alignment. Con-
cerning the TDI, we will present the RF measurements per-
formed before and after the upgrade, comparing the result
to heating and tune shift beam measurements. For the TCTs,
we will study how the higher order modes (HOM) intro-
duced by the BPM addition have been cured by means of
ferrite placement in the device. The impedance mitigation
campaign has been supported by RF measurements whose
results are in good agreement with GdfidL and CST simula-
tions. The presence of undamped low frequency modes is
proved not to be detrimental to the safe LHC operation
A facility to Search for Hidden Particles (SHiP) at the CERN SPS
A new general purpose fixed target facility is proposed at the CERN SPS
accelerator which is aimed at exploring the domain of hidden particles and make
measurements with tau neutrinos. Hidden particles are predicted by a large
number of models beyond the Standard Model. The high intensity of the SPS
400~GeV beam allows probing a wide variety of models containing light
long-lived exotic particles with masses below (10)~GeV/c,
including very weakly interacting low-energy SUSY states. The experimental
programme of the proposed facility is capable of being extended in the future,
e.g. to include direct searches for Dark Matter and Lepton Flavour Violation.Comment: Technical Proposa
New Results from the Cryogenic Dark Matter Search Experiment
Using improved Ge and Si detectors, better neutron shielding, and increased
counting time, the Cryogenic Dark Matter Search (CDMS) experiment has obtained
stricter limits on the cross section of weakly interacting massive particles
(WIMPs) elastically scattering from nuclei. Increased discrimination against
electromagnetic backgrounds and reduction of neutron flux confirm
WIMP-candidate events previously detected by CDMS were consistent with neutrons
and give limits on spin-independent WIMP interactions which are >2X lower than
previous CDMS results for high WIMP mass, and which exclude new parameter space
for WIMPs with mass between 8-20 GeV/c^2.Comment: 4 pages, 4 figure
Accidental Oleandrum (Nerium Oleander L.) Ingestion: Anatomo-Pathological consequences in livestock species
The oleander (Nerium oleander L.) is a flowering and evergreen shrub or small tree, belonging to the Dogbane family, cultivated as ornamental plants in gardens and public city areas. These plants, distributed originally in Asia and Mediterranean area, grow in many parts of the world, particularly in warm temperate and subtropical regions. Oleander is considered noxious weed and its toxicity has been known since ancient times. All parts of plants, including stems, leaves, young shoots, flowers, nectar, sap and products induced by combustion are toxic. The poisoning effects of plant induced sever negative changes especially in the heart, also in the lung, in the liver and in the kidney. Accidental and experimental cases of oleander poisonings have been described in several species. Several cases of accidental ingestion in human and animals have been reported from across the world. Therefore, this review summarizes the main anatomo-pathological effects found in livestock species after accidental oleandrum poisoning
Exclusion Limits on the WIMP-Nucleon Cross-Section from the First Run of the Cryogenic Dark Matter Search in the Soudan Underground Lab
The Cryogenic Dark Matter Search (CDMS-II) employs low-temperature Ge and Si
detectors to seek Weakly Interacting Massive Particles (WIMPs) via their
elastic scattering interactions with nuclei. Simultaneous measurements of both
ionization and phonon energy provide discrimination against interactions of
background particles. For recoil energies above 10 keV, events due to
background photons are rejected with >99.99% efficiency. Electromagnetic events
very near the detector surface can mimic nuclear recoils because of reduced
charge collection, but these surface events are rejected with >96% efficiency
by using additional information from the phonon pulse shape. Efficient use of
active and passive shielding, combined with the the 2090 m.w.e. overburden at
the experimental site in the Soudan mine, makes the background from neutrons
negligible for this first exposure. All cuts are determined in a blind manner
from in situ calibrations with external radioactive sources without any prior
knowledge of the event distribution in the signal region. Resulting
efficiencies are known to ~10%. A single event with a recoil of 64 keV passes
all of the cuts and is consistent with the expected misidentification rate of
surface-electron recoils. Under the assumptions for a standard dark matter
halo, these data exclude previously unexplored parameter space for both
spin-independent and spin-dependent WIMP-nucleon elastic scattering. The
resulting limit on the spin-independent WIMP-nucleon elastic-scattering
cross-section has a minimum of 4x10^-43 cm^2 at a WIMP mass of 60 GeV/c^2. The
minimum of the limit for the spin-dependent WIMP-neutron elastic-scattering
cross-section is 2x10^-37 cm^2 at a WIMP mass of 50 GeV/c^2.Comment: 37 pages, 42 figure
Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells
Introduction
Patients with autoimmune thyroid disease (AITD) show defects in their immune-regulatory mechanisms. Herein we assessed the expression and function of galectin-1 and galectin-9 (Gal-1, Gal-9) in dendritic cells (DCs) from patients with AITD.
Materials and Methods
Peripheral blood samples from 25 patients with Graves’ disease (GD), 11 Hashimoto’s thyroiditis (HT), and 24 healthy subjects were studied. Thyroid tissue samples from 44 patients with AITD and 22 patients with goiter were also analyzed. Expression and function of Gal-1 and Gal-9 was assessed by quantitative RT-PCR, immunofluorescence and flow cytometry.
Results
A diminished expression of Gal-9, but not of Gal-1, by peripheral blood DCs was observed in GD patients, mainly in those with Graves´ ophthalmopathy, and a significant negative association between disease severity and Gal-9 expression was detected. In addition, the mRNA levels of Gal-9 and its ligand TIM-3 were increased in thyroid tissue from AITD patients and its expression was associated with the levels of Th1/Th12/Th17 cytokines. Immunofluorescence studies proved that intrathyroidal Gal-9 expression was confined to DCs and macrophages. Finally, in vitro functional assays showed that exogenous Gal-9 had a suppressive effect on the release of Th1/Th2/Th17 cytokines by DC/lymphocyte autologous co-cultures from both AITD patients and healthy controls.
Conclusions
The altered pattern of expression of Gal-9 in peripheral blood DCs from GD patients, its correlation with disease severity as well as its ability to suppress cytokine release suggest that Gal-9 could be involved in the pathogenesis of AITDThis work was supported by grants from
the Fondo de Investigaciones Sanitarias (FISS) PI10/
02521 and S2010/BMD-2328 TIRONET (Comunidad
de Madrid), Spain (to MM) and the Fondo de
Cooperación Internacional en Ciencia y Tecnología
(FONCICYT) 95395, European Union-México (to
RGA
Exclusion Limits on the WIMP-Nucleon Cross-Section from the Cryogenic Dark Matter Search
The Cryogenic Dark Matter Search (CDMS) employs Ge and Si detectors to searchfor WIMPs via their elastic-scattering interactions with nuclei whilediscriminating against interactions of background particles. CDMS data givelimits on the spin-independent WIMP-nucleon elastic-scattering cross-sectionthat exclude unexplored parameter space above 10 GeV~c WIMP mass and, atL, the entire 3 allowed region for the WIMP signal reported bythe DAMA experiment
Venous Thromboembolism and Decreased Serum Albumin in Children with Acute Lymphoblastic Leukemia: A Challenge for Endothelial Homeostasis?
Background: Serum albumin is crucial for critically ill patients. To date, several reports have focused on the influence of lower albumin levels on poorer prognosis and disease outcome in different subsets of critical clinical conditions varying from sepsis, to cirrhosis, renal failure, and cancer. In the last few years, investigators reported the role of serum albumin levels in predicting the thrombotic risk in patients with nephrotic syndrome, and, in particular, the degree of hypoalbuminemia seemed to influence the risk of thromboembolism. Decreased serum albumin has been associated with the risk of venous thromboembolism and mortality in adult cancer patients after ending chemotherapy for different malignancies. Aims: We aimed to investigate the role of serum albumin in a cohort of children diagnosed as having VTE (venous thromboembolism) during their treatment for acute lymphoblastic leukemia (ALL) compared to ALL children who did not experience VTE. Methods: A nested case-control study was conducted at the Pediatric Oncology and Hematology Department, University Hospital of Bari. A total of 167 patients were diagnosed as having ALL and treated according to AIEOP-BFM ALL 2000-R2006 protocol. Among these, 12 cases of VTE were recorded and matched to 31 controls, for a total of 43 ALL patients (30 males, aged 1.2-16.6 years) enrolled in the present study. Serum albumin level was collected at diagnosis-before the start of any treatment-(time point 0) and at the moment of the VTE or corresponding time point of the protocol (time point 1). Information on inherited thrombophilia genotype were also recorded. Results: Patients presenting VTE showed a marked reduction of average albumin levels as compared to the control children: t0-t1 1.1 IC (95%) = (0.55, 1.65) vs. 0.31 IC (95%) = (0.08, 0.55); p < 0.005. Conclusions: The reduction of serum albumin levels in our cohort might be an expression of altered vascular and endothelial homeostasis, likely predisposing to VTE. This important clinical observation warrants further larger studies
Can scenario-planning support community-based natural resource management? Experiences from three countries in latin america
Community Based Natural Resource Management (CBNRM) is a concept critical to managing socio-ecological systems, but whose implementation needs strengthening. Scenario-planning is one approach that may offer benefits relevant to CBNRM, but whose potential is not yet well understood. We therefore designed, trialled and evaluated a scenario-planning method intended to support CBNRM at three cases, located in Colombia, Mexico and Argentina. Implementing scenario-planning was judged as worthwhile in all three cases, although aspects of it could be challenging to facilitate. The benefits generated were relevant to strengthening CBNRM: encouraging the participation of local people and using their knowledge; enhanced consideration and adaption of future change; and supporting the development of systems thinking. Tracing exactly when and how these benefits arise is challenging, but two elements of the method seemed particularly useful. Firstly, using a systematic approach to discuss how drivers of change may affect local socio-ecological systems helped to foster systems thinking and identify connections between issues. Secondly, explicitly focusing on how to use and respond to scenarios helped identify specific practical activities ('response options') that would support CBNRM despite the pressures of future change. Discussions about response options also highlighted the need for support by other actors (e.g. policy groups): this raises the question of when and how other actors and other sources of knowledge should be involved in scenario-planning, so as to encourage their buy-in to actions identified by the process. We suggest other CBNRM initiatives may benefit from adapting and applying scenario-planning. However, these initiatives should be carefully monitored since further research is required to understand how and when scenario-planning methods may produce benefits, and their strengths and weaknesses versus other methods
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