2,037 research outputs found

    Grid-enabled Workflows for Industrial Product Design

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    This paper presents a generic approach for developing and using Grid-based workflow technology for enabling cross-organizational engineering applications. Using industrial product design examples from the automotive and aerospace industries we highlight the main requirements and challenges addressed by our approach and describe how it can be used for enabling interoperability between heterogeneous workflow engines

    How British Mirpuri Pakistani women identify themselves and form their id

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    This thesis examines the experiences and the attitudes of Bradford females who have Pakistani Mirpuri heritage. The study has involved people of different ages ranging from sixteen to thirty-five and older women aged in their forties and beyond. The women explore their relationship with their parents, the biraderi (their extended family), career and educational aspirations, involvement with religion and culture and how these fit into their personal identities. The data was gathered incrementally over three stages. Each stage was equally important, and themes emerged at each stage, which were then explored further. The data comes out from a number of questionnaires, which were followed by interviews. The research evidence creates consistent pictures and provides an insight into the lives and experiences of Bradford females, of Pakistani Mirpuri origin. The concern was to explore the notions of their sense of personal identity in the face of conflicting cultures and conflicts between culture and religion. The research evidence shows that younger women believed they did share a close relationship with their parents. At times this relationship was tested. The evidence shows that an area of major inter-generational tension was where parents were trying to control the behaviours of younger women by using cultural interpretations of Islam. This was particularly mentioned by younger women in relation to education, careers, and marriage and on issues of freedom generally. The relationship of younger women, with the biraderi (kin) is not as close as their parents' relationship with it. Younger women are leading independent lives and have high career and educational aspirations. The majority of the respondents felt their parents had supported their aspirations. The evidence shows that younger women feel comfortable with the freedom they have. They wanted to be able to fulfil their education and career aspirations and socialise with friends. The younger women felt they understood Islam and followed religion more than culture. They felt they were able to distinguish between culture was and where parents were confusing religion and culture. The majority of women in this study described having multiple identities and were comfortable with this. Being British did not mean they had to compromise them as Muslims. The thesis demonstrates that Pakistanis are not homogonous and that there are many differences based on gender, cast and sect. At the core, however, is the sense of personal identity and the use the women made of their religious beliefs, not as a sign of the subjection to their inheritance but a symbol of their sense of personal independence

    Clarithromycin induced digoxin toxicity: case report and review

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    Identification and management of atypical Hemolytic Uremic Syndrome immediately post heart transplantation

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    Atypical hemolytic uremic syndrome (aHUS) is a serious hematologic disorder with high mortality if left untreated. A comprehensive literature review revealed only two cases of aHUS post–heart transplantation. In both cases the disease developed after induction of calcineurin inhibitor therapy. We report a case of immediate post–heart transplantation aHUS, manifested before the induction of, and therefore not associated with, calcineurin inhibitor

    Missense mutations at homologous positions in the fourth and fifth laminin A G-like domains of eyes shut homolog cause autosomal recessive retinitis pigmentosa

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    Purpose: To describe two novel mutations in the eyes shut homolog (EYS) gene in two families with autosomal recessive retinitis pigmentosa (arRP) from Pakistan and Indonesia. Methods: Genome-wide linkage and homozygosity mapping were performed using single nucleotide polymorphism microarray analysis in affected members of the two arRP families. Sequence analysis was performed to identify genetic changes in protein coding exons of EYS. Results: In the Indonesian and Pakistani families, homozygous regions encompassing the EYS gene at 6q12 were identified, with maximum LOD scores of 1.8 and 3.6, respectively. Novel missense variants in the EYS gene (p.D2767Y and p.D3028Y) were found in the Pakistani and Indonesian families, respectively, that co-segregate with the disease phenotype. Interestingly, the missense variants are located at the same homologous position within the fourth and fifth laminin A G-like domains of EYS. Conclusions: To date, mostly protein-truncating mutations have been described in EYS, while only few patients have been described with pathogenic compound heterozygous missense mutations. The mutations p.D2767Y and p.D3028Y described in this study affect highly conserved residues at homologous positions in laminin A G-like domains and support the notion that missense mutations in EYS can cause arRP

    How British Mirpuri Pakistani women identify themselves and form their id

    Get PDF
    This thesis examines the experiences and the attitudes of Bradford females who have Pakistani Mirpuri heritage. The study has involved people of different ages ranging from sixteen to thirty-five and older women aged in their forties and beyond. The women explore their relationship with their parents, the biraderi (their extended family), career and educational aspirations, involvement with religion and culture and how these fit into their personal identities. The data was gathered incrementally over three stages. Each stage was equally important, and themes emerged at each stage, which were then explored further. The data comes out from a number of questionnaires, which were followed by interviews. The research evidence creates consistent pictures and provides an insight into the lives and experiences of Bradford females, of Pakistani Mirpuri origin. The concern was to explore the notions of their sense of personal identity in the face of conflicting cultures and conflicts between culture and religion. The research evidence shows that younger women believed they did share a close relationship with their parents. At times this relationship was tested. The evidence shows that an area of major inter-generational tension was where parents were trying to control the behaviours of younger women by using cultural interpretations of Islam. This was particularly mentioned by younger women in relation to education, careers, and marriage and on issues of freedom generally. The relationship of younger women, with the biraderi (kin) is not as close as their parents' relationship with it. Younger women are leading independent lives and have high career and educational aspirations. The majority of the respondents felt their parents had supported their aspirations. The evidence shows that younger women feel comfortable with the freedom they have. They wanted to be able to fulfil their education and career aspirations and socialise with friends. The younger women felt they understood Islam and followed religion more than culture. They felt they were able to distinguish between culture was and where parents were confusing religion and culture. The majority of women in this study described having multiple identities and were comfortable with this. Being British did not mean they had to compromise them as Muslims. The thesis demonstrates that Pakistanis are not homogonous and that there are many differences based on gender, cast and sect. At the core, however, is the sense of personal identity and the use the women made of their religious beliefs, not as a sign of the subjection to their inheritance but a symbol of their sense of personal independence.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

    Persepsi Pelaku Usaha Perikanan terhadap Kinerja Penyuluh Perikanan

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    Penelitian mengenai persepsi pelaku USAha terhadap kinerja penyuluh perikanan dilakukan pada bulan April sampai bulan Mei 2011. Lokasi penelitian di 11 provinsi yang tersebar di 13 kabupaten/kota. Jumlah responden sebanyak 89 orang. Penelitian ini bertujuan untuk mengetahui persepsi pelaku USAha perikanan terhadap kinerja penyuluh perikanan. Hasil penelitian menunjukkan keberadaan penyuluh masih sangat dibutuhkan oleh pelaku USAha, materi yang dibutuhkan terkait dengan peningkatan produksi USAhanya, dan cara yang diinginkan pelaku USAha adalah penyuluh dapat memberi contoh USAha perikanan sesuai kebutuhan pelaku USAha
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