The impact of strategic marketing on enterprise competitiveness

Today, the problem of the enterprise's competitiveness is more urgent than ever for the nationa

Author as a corporal subject of a. Huxley’s works

The relevance of the problem studied in the article is conditioned by the fact that A. Huxley’s works are regarded in the context of the modern theory of mimesis for the first time. The aim of the article is to analyze the author’s problem as a corporal subject of Huxley’s works in the context of the modern theory of mimesis. The leading method for studying this problem is the analytical anthropology of literature which allows describing mimetic features and the author’s image as a corporal subject of Huxley’s works. The main attention in the article is paid to the artistically embodied forms of the author’s corporality. The article may be useful for philologists, philosophers, for developing courses and seminars on the history of the English literature, and also within courses on the anthropology of literature. © 2016 Falaleeva et al

Primary lymphangiectasia of the gastrointestinal tract

Intestinal lymphangiectasia is a very rare pathology, characterized by the presence of enlarged lymphatic vessels in all layers of the intestinal wall and in the mesentery. As a result, "lymphatic lakes" are formed, through which lymph exudates into the lumen of the intestine. The main manifestation is hypoproteinemic edema. Diagnosis of the disease is based on laboratory-instrumental methods of investigation, including by determining in the stool α-1 antitrypsin as a screening test. Treatment includes: a diet rich in calcium, trace elements, be sure to use medicinal foods enriched with medium chain triglycerides, substitution and symptomatic therapy

The role of timely rheumatoid arthritis treatment effectiveness control

Background. Regular assessment of rheumatoid arthritis (RA) activity is a key factor in therapy effectiveness improving. Aim. To prove that timely RA treatment control recommended by modern guidelines improves outcomes and reduce disability in real clinical practice. Materials and methods. Fourty patients with RA hospitalized at the University Clinical Hospital from January 2021 to January 2023 were included into a retrospective single-center study and divided into 2 groups. In the first group, RA activity was monitored after 3, 6, and 12 months, with therapy adjusted if necessary. In the second group, monitoring of RA activity was carried out after 12 months. The patients underwent clinical, laboratory and instrumental examinations (Tender Joint Count (TJC) and Swollen Joint Count (SJC), common blood test with differential white blood cell count, ESR, biochemical blood test, CRP, RF, ACCP, hands, feet and chest X-ray, ECG). RA activity was assessed using DAS28, CDAI, SDAI indices in both groups. Results. RA activity control after 12 months in patients of the first group regularly observed by a rheumatologist was better than in patients of the second group, who visited rheumatologist again only in 12 months. DAS28 decreased significantly, from 4.71±0.80 to 3.08±0.70 in the group with regular monitoring during the observation period. Remission or low activity was achieved by 75% of patients (5% remission and 70% low activity). Less dynamics was registered in patients of the second group: the initial DAS28 was 4.50±0.74, DAS28 after 12 months was 4.36±0.64, which corresponds to moderate activity. Low activity was achieved in 15% of patients, remission was not achieved in any patient. Conclusion. Strict adherence to the recommended terms for disease activity monitoring is necessary for successful RA treatment in real clinical practice

HI study of the environment around ESO 243-49, the host galaxy of an intermediate mass black hole

The lenticular galaxy ESO 243-49 hosts the ultraluminous X-ray source HLX-1, the best candidate intermediate mass black hole (IMBH) currently known. The environments of IMBHs remain unknown, however the proposed candidates include the nuclei of dwarf galaxies or globular clusters. Evidence at optical wavelengths points at HLX-1 being the remnant of an accreted dwarf galaxy. Here we report the Australia Telescope Compact Array radio observations of HI emission in and around ESO 243-49 searching for signatures of a recent merger event. No HI line emission is detected in ESO 243-49 with a 5$\sigma$ upper limit on the HI gas mass of a few $10^8 M_{\odot}$. A likely reason for this non-detection is the cluster environment depleting ESO 243-49's HI gas reservoir. The upper limit is consistent with an interpretation of HLX-1 as a dwarf satellite of ESO 243-49, however more sensitive observations are required for a detection. We detect ~$5 \times 10^8 M_{\odot}$ of HI gas in the peculiar spiral galaxy AM 0108-462, located at a projected distance of ~170 kpc from ESO 243-49. This amount of HI gas is ~10 times less than in spiral galaxies with similar optical and near-infrared properties in the field, strengthening the conclusion that the cluster environment indeed depletes the HI gas reservoir of these two galaxies. Here we also report observations of AM 0108-462 in several optical and near-infrared bands using the Magellan 6.5 m telescopes, and archival X-ray and ultraviolet observations with XMM-Newton and Swift. These data combined with the HI line data suggest it is likely that AM 0108-462 is experiencing a merger event.Comment: 12 pages, 9 figures, accepted for publication in MNRA

The new functional products inclusion in the complex rehabilitation and preventive programs in athletes with musculoskeletal disorders

The review presents an urgent problem of modern sports medicine — the development and inclusion of new nutritive and metabolic food products in the treatment of athletes with injuries and diseases of the musculoskeletal system. The analysis of the main etiological factors of the musculoskeletal disorders in athletes is presented. The study of the anatomical, histological and functional features of the bone-cartilaginous structures in athletes made it possible to establish the priority macro- and micronutrients, which should be the basis in modern specialized and functional food products. Brief composition characteristics of the new canned food “Enmit-beef” and dry protein concentrate “Ostov” (for the drink preparation) are presented. The preliminary results of the use of these functional meat-based products indicate their effectiveness in rehabilitation and treatment of athletes with musculoskeletal disorders

ELECTRONIC GREEN'S REACTIVITY CHART BASED ON BIG DATA ANALYSIS

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Comparison of REMS, NEWS, qSOFA and SIRS criteria scales for sepsis prediction in patients with diagnosis “SARS-CoV-2, virus unidentified”: a retrospective observational study

Background. Despite ample research on the coronavirus infection sequence and therapy, the incidence of adverse outcomes remains very high. Sepsis stands among the major factors greatly complicating treatment and increasing the risk of death. A timely identification of highrisk sepsis patients is a cornerstone of effective sepsis prevention.Objectives. A comparative prognostic power assessment between the quick Sequential Organ Failure Assessment (qSOFA) scale, National Early Warning Score (NEWS), Initial Prehospital Rapid Emergency Medicine Score (REMS) and the Systemic Inflammatory Response Syndrome (SIRS) criteria for sepsis detection in anaesthetic intensive care patients with a diagnosis: SARS-CoV-2, virus unidentified.Methods. A retrospective observational study included 166 patients over 18-year age with unconfirmed infection (ICD-10 code U07.2). The qSOFA, NEWS, REMS and SIRS point estimates were obtained from each patient. The patients were retrospectively divided in two cohorts by sepsis presence (Sepsis-3 criteria) to determine the express scales power in evaluating the risk of sepsis (estimated as area under ROC curve, AUROC).Results. Data on 102 patients were included in the final analysis. Fifty-eight (57%) patients were terminal, and 55 (54%) developed sepsis. The estimates are as follows: NEWS — AUROC 0.848 [95% confidence interval (CI) 0.764–0.912], sensitivity 76.36% [95% CI 63.0–86.8], specificity 82.98% [95% CI 69.2–92.4], optimal cut-off threshold >5 points; qSOFA — AUROC 0.700 [95% CI 0.602–0.787], sensitivity 76.36% [95% CI 63.0–86.8], specificity 61.70% [95% CI 46.4–75.5], optimal cut-off threshold >0 points; REMS — AUROC 0.739 [95% CI 0.643–0.821], sensitivity 69.09% [95% CI 55.2–80.9], specificity 65.96% [95% CI 50.7–79.1], optimal cut-off threshold >5 points; SIRS criteria — AUROC 0.723 [95% CI 0.626–0.807], sensitivity 98.18% [95% CI 90.3–100.0], specificity 31.91% [95% CI 19.1–47.1], optimal cut-off threshold >0 points.Conclusion. The NEWS scale revealed a good prognostic power to estimate the risk of sepsis in patients with suspected COVID-19 disease. The qSOFA, REMS scales and SIRS criteria possess a good calibration capacity, albeit insufficient resolution, which limits their prognostic value

A Comparison of Photometric Redshift Techniques for Large Radio Surveys

Future radio surveys will generate catalogs of tens of millions of radio sources, for which redshift estimates will be essential to achieve many of the science goals. However, spectroscopic data will be available for only a small fraction of these sources, and in most cases even the optical and infrared photometry will be of limited quality. Furthermore, radio sources tend to be at higher redshift than most optical sources (most radio surveys have a median redshift greater than 1) and so a significant fraction of radio sources hosts differ from those for which most photometric redshift templates are designed. We therefore need to develop new techniques for estimating the redshifts of radio sources. As a starting point in this process, we evaluate a number of machine-learning techniques for estimating redshift, together with a conventional template-fitting technique. We pay special attention to how the performance is affected by the incompleteness of the training sample and by sparseness of the parameter space or by limited availability of ancillary multiwavelength data. As expected, we find that the quality of the photometric-redshift degrades as the quality of the photometry decreases, but that even with the limited quality of photometry available for all-sky-surveys, useful redshift information is available for the majority of sources, particularly at low redshift. We find that a template-fitting technique performs best in the presence of high-quality and almost complete multi-band photometry, especially if radio sources that are also X-ray emitting are treated separately, using specific templates and priors. When we reduced the quality of photometry to match that available for the EMU all-sky radio survey, the quality of the template-fitting degraded and became comparable to some of the machine-learning methods. Machine learning techniques currently perform better at low redshift than at high redshift, because of incompleteness of the currently available training data at high redshifts

Liquid metals for solar power systems

The use of liquid metals in solar power systems is not new. The receiver tests with liquid sodium in the 1980s at the Plataforma Solar de Almería (PSA) already proved the feasibility of liquid metals as heat transfer fluid. Despite the high efficiency achieved with that receiver, further investigation of liquid metals in solar power systems was stopped due to a sodium spray fire. Recently, the topic has become interesting again and the gained experience during the last 30 years of liquid metals handling is applied to the concentrated solar power community. In this paper, recent activities of the Helmholtz Alliance LIMTECH concerning liquid metals for solar power systems are presented. In addition to the components and system simulations also the experimental setup and results are included