The Ideal Refugees: Gender, Islam, and the Sahrawi Politics of Survival, by Elena Fiddian-Qasmiyeh

The Ideal Refugees: Gender, Islam, and the Sahrawi Politics of Survival by Elena Fiddian-QasmiyehSyracuse, NY: Syracuse University Press, 2014, pp. 30

Representation, civil war and humanitarian intervention: the international politics of naming Algerian violence, 1992-2002

This examination criticises some of the main textual efforts within the self-identified politiography of Algeria that have attempted to help make the last twenty years of violent conflict in Algeria intelligible to Western audiences. It attends to the way in which particular representations of Algerian violence were problematised within, and cross-problematised with, prevailing international security discourses and practices, especially the concurrently emergent litterature on civil wars and armed humanitarian intervention. Unsatisfied with general international response to the conflict in Algeria in the 1990s, particularly the major massacres of 1997 and 1998, this study questions how certain problematisations were used to understand the violence and how those renderings contributed to the troubled relationship between the representation of mass violence in Algeria and international efforts to intervene against it. As a study in politiography, the primary object of analysis here is not the entire discursive field of Algerian violence but rather select yet influential scholarly texts within the genre of late Algerian violence. While these works helped co-constitute the broader discursive formations of Algerian violence that enabled its own representation as such, this examination does not necessarily address them vis-à-vis unique, superior or competing representations drawn from the traditionally privileged sites of initial discursive production of international security. The primary method of critique here is deconstructive in so far as it simply uses the texts — their arguments, their evidence and their archival logic — against themselves. Borrowing insights from currents in recent neopragmatist thought, this study seeks to reverse engineer some of the more dominant international problematisations of Algerian violence, so as to unearth the deeper politics of naming built into specific representations of Algeria and more generic frameworks of international security. After first exploring the conflict’s contested political and economic etiology (chapter three), as well as its disputed classification as a civil war (chapter four), this study closely examines the interpretations of the most intense civilian massacres, those that occurred between August 1997 and January 1998 (chapters five and six). How these representations resulted in the threat of (armed) humanitarian intervention are of particular concern (chapter seven), as are the ways in which foreign actors have attempted to historically contextualise Algeria’s alleged tradition and culture of violence (chapter eight). The aim is not to produce — though it cannot but help contribute to — a new history or account of the politics of the Algerian conflict and its internationalisation. The intent is first to underscore the inherent yet potentially auspicious dangers within all problematisations of mass violence. Secondly, it is to advocate for ironic forms of politiography, given the politics always-already embedded within acts of naming, particularly when it comes to questions of mass violence. A politiography that is able to appreciate the contingency of representation and intervention, and so underscores the need for a more deliberately and deliberative ethical and democratic politics of representation in the face of atrocity

Management of Adult Anterior Urethral Stricture Disease: Nationwide Survey Among Urologists in The Netherlands

BACKGROUND: Adult anterior urethral stricture disease is most often treated with dilatation or direct vision internal urethrotomy (DVIU). Although evidence suggests that anastomotic urethroplasty for short bulbar strictures is more efficient and cost effective in the long term, no consensus exists. It is unclear by whom and how often urethroplasties are performed in The Netherlands and how results are being evaluated.OBJECTIVE: To determine national practice patterns on management of anterior urethral strictures among Dutch urologists. This information will help to define the nationwide need for training in urethral surgery.DESIGN, SETTING, AND PARTICIPANTS: We conducted a 16-question survey among all 323 Dutch urologists.RESULTS AND LIMITATIONS: The response rate was 74%. DVIU was practised by 97% of urologists. Urethroplasty was performed at least once yearly by 23%, with 6% performing more than five urethroplasties annually. In the group of urologists younger than 50 yr of age, 13% performed urethroplasty, with 3% of those performing more than five annually. In the case of a 3.5-cm-long bulbar stricture, DVIU was preferred by 49% of responders. Even after two recurrences, 20% continued to manage a 1-cm-long bulbar stricture endoscopically. Of responders, 79% believed that urethroplasty should be proposed only after a failed endoscopic attempt. Diagnostic workup and evaluation of success varied greatly.CONCLUSIONS: Most Dutch urologists believe that urethroplasty is an option only after failed DVIU. Endoscopic procedures are widely used, even when the risk of recurrence is virtually 100%. The definition of success is hampered by nonstandardised methods of follow-up. Only a small group of mainly older urologists frequently performs urethroplasties. Training programmes seem necessary to guarantee a high standard of care for stricture disease in The Netherlands. A pan-European practice survey might be interesting to clarify the need for centralised fellowship programmes.</p

Autoimmunity in Arabidopsis acd11 Is Mediated by Epigenetic Regulation of an Immune Receptor

Certain pathogens deliver effectors into plant cells to modify host protein targets and thereby suppress immunity. These target modifications can be detected by intracellular immune receptors, or Resistance (R) proteins, that trigger strong immune responses including localized host cell death. The accelerated cell death 11 (acd11) “lesion mimic” mutant of Arabidopsis thaliana exhibits autoimmune phenotypes such as constitutive defense responses and cell death without pathogen perception. ACD11 encodes a putative sphingosine transfer protein, but its precise role during these processes is unknown. In a screen for lazarus (laz) mutants that suppress acd11 death we identified two genes, LAZ2 and LAZ5. LAZ2 encodes the histone lysine methyltransferase SDG8, previously shown to epigenetically regulate flowering time via modification of histone 3 (H3). LAZ5 encodes an RPS4-like R-protein, defined by several dominant negative alleles. Microarray and chromatin immunoprecipitation analyses showed that LAZ2/SDG8 is required for LAZ5 expression and H3 lysine 36 trimethylation at LAZ5 chromatin to maintain a transcriptionally active state. We hypothesize that LAZ5 triggers cell death in the absence of ACD11, and that cell death in other lesion mimic mutants may also be caused by inappropriate activation of R genes. Moreover, SDG8 is required for basal and R protein-mediated pathogen resistance in Arabidopsis, revealing the importance of chromatin remodeling as a key process in plant innate immunity

Genetic Diversity among Enterococcus faecalis

Enterococcus faecalis, a ubiquitous member of mammalian gastrointestinal flora, is a leading cause of nosocomial infections and a growing public health concern. The enterococci responsible for these infections are often resistant to multiple antibiotics and have become notorious for their ability to acquire and disseminate antibiotic resistances. In the current study, we examined genetic relationships among 106 strains of E. faecalis isolated over the past 100 years, including strains identified for their diversity and used historically for serotyping, strains that have been adapted for laboratory use, and isolates from previously described E. faecalis infection outbreaks. This collection also includes isolates first characterized as having novel plasmids, virulence traits, antibiotic resistances, and pathogenicity island (PAI) components. We evaluated variation in factors contributing to pathogenicity, including toxin production, antibiotic resistance, polymorphism in the capsule (cps) operon, pathogenicity island (PAI) gene content, and other accessory factors. This information was correlated with multi-locus sequence typing (MLST) data, which was used to define genetic lineages. Our findings show that virulence and antibiotic resistance traits can be found within many diverse lineages of E. faecalis. However, lineages have emerged that have caused infection outbreaks globally, in which several new antibiotic resistances have entered the species, and in which virulence traits have converged. Comparing genomic hybridization profiles, using a microarray, of strains identified by MLST as spanning the diversity of the species, allowed us to identify the core E. faecalis genome as consisting of an estimated 2057 unique genes

Bone regeneration and stem cells.

?  Introduction ?  Bone fracture healing and healing problems ?  Biomaterial scaffolds and tissue engineering in bone formation -  Bone tissue engineering -  Biomaterial scaffolds -  Synthetic scaffolds -  Micro- and nanostructural properties of scaffolds -  Conclusion ?  Mesenchymal stem cells and osteogenesis -  Bone tissue -  Origin of osteoblasts -  Isolation and characterization of bone marrow derived MSC -  In vitro differentiation of MSC into osteoblast lineage cells -  In vivo differentiation of MSC into bone -  Factors and pathways controlling osteoblast differentiation of hMSC -  Defining the relationship between osteoblast and adipocyte differentiation from MSC -  MSC and sex hormones -  Effect of aging on osteoblastogenesis -  Conclusion ?  Embryonic, foetal and adult stem cells in osteogenesis -  Cell-based therapies for bone -  Specific features of bone cells needed to be advantageous for clinical use -  Development of therapeutic biological agents -  Clinical application concerns -  Conclusion ?  Platelet-rich plasma (PRP), growth factors and osteogenesis -  PRP effects in vitro on the cells involved in bone repair -  PRP effects on osteoblasts -  PRP effects on osteoclasts -  PRP effects on endothelial cells -  PRP effects in vivo on experimental animals -  The clinical use of PRP for bone repair -  Non-union -  Distraction osteogenesis -  Spinal fusion -  Foot and ankle surgery -  Total knee arthroplasty -  Odontostomatology and maxillofacial surgery -  Conclusion ?  Molecular control of osteogenesis -  TGF-β signalling -  FGF signalling -  IGF signalling -  PDGF signalling -  MAPK signalling pathway -  Wnt signalling pathway -  Hedgehog signalling -  Notch signalling -  Ephrin signalling -  Transcription factors regulating osteoblast differentiation -  Conclusion ?  Summary This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed

Western Sahara: war, nationalism, and conflict irresolution

The Western Sahara conflict has proven to be one of the most protracted and intractable struggles facing the international community. Pitting local nationalist determination against Moroccan territorial ambitions, the dispute is further complicated by regional tensions with Algeria and the geo-strategic concerns of major global players, including the United States, France, and the territory’s former colonial ruler, Spain. Since the early 1990s, the UN Security Council has failed to find a formula that will delicately balance these interests against Western Sahara’s long-denied right to a self-determination referendum as one of the last UN-recognized colonies. The widely-lauded first edition was the first book-length treatment of the issue in the previous two decades. Zunes and Mundy examined the origins, evolution, and resilience of the Western Sahara conflict, deploying a diverse array of sources and firsthand knowledge of the region gained from multiple research visits. Shifting geographical frames—local, regional, and international—provided for a robust analysis of the stakes involved. With the renewal of the armed conflict, continued diplomatic stalemate, growing waves of nonviolent resistance in the occupied territory, and the recent U.S. recognition of Morocco’s annexation, this new revised and expanded paperback edition brings us up-to-date on a long-forgotten conflict that is finally capturing the world’s attention.https://repository.usfca.edu/faculty_books_all/1081/thumbnail.jp