1,105 research outputs found
Response of beam-to-column web cleated joints for FRP pultruded members
Physical testing is used to characterize the structural properties of beam-to-column joints, comprising pultruded fiber-reinforced polymer (FRP) H-shapes of depth 203 mm, connected by 128 mm-long web cleats and two M16 bolts per leg. Testing is performed on two batches of nominally identical specimens. One batch had web cleats of pultruded FRP and the other had structural steel. The structural behavior of the joints is based on their moment-rotation responses, failure modes, and serviceability vertical deflection limits. Joints with FRP cleats failed by delamination cracking at the top of the cleats, and when the cleats were of steel, the FRP failure occurred inside the column members. Neither failure mode is reported in the design manuals from pultruders. At the onset of the FRP damage, it was found that the steel joints were twice as stiff as the FRP joints. On the basis of a characteristic (damage) rotation, calculated in accordance with Eurocode 0, the serviceability deflection limits are established to be span/300 and span/650 for the joints with FRP and steel cleats, respectively. This finding suggests that appropriate deflection limits, in relation to cleated connections, should be proposed in manufacturesâ design manuals and relative design standards and design codes. Failure to address the serviceability, by the engineer of record, could lead to unreliable designs
ALMA CO J=6-5 observations of IRAS16293-2422: Shocks and entrainment
Observations of higher-excited transitions of abundant molecules such as CO
are important for determining where energy in the form of shocks is fed back
into the parental envelope of forming stars. The nearby prototypical and
protobinary low-mass hot core, IRAS16293-2422 (I16293) is ideal for such a
study. The source was targeted with ALMA for science verification purposes in
band 9, which includes CO J=6-5 (E_up/k_B ~ 116 K), at an unprecedented spatial
resolution (~0.2", 25 AU). I16293 itself is composed of two sources, A and B,
with a projected distance of 5". CO J=6-5 emission is detected throughout the
region, particularly in small, arcsecond-sized hotspots, where the outflow
interacts with the envelope. The observations only recover a fraction of the
emission in the line wings when compared to data from single-dish telescopes,
with a higher fraction of emission recovered at higher velocities. The very
high angular resolution of these new data reveal that a bow shock from source A
coincides, in the plane of the sky, with the position of source B. Source B, on
the other hand, does not show current outflow activity. In this region, outflow
entrainment takes place over large spatial scales, >~ 100 AU, and in small
discrete knots. This unique dataset shows that the combination of a
high-temperature tracer (e.g., CO J=6-5) and very high angular resolution
observations is crucial for interpreting the structure of the warm inner
environment of low-mass protostars.Comment: Accepted for publication in A&A Letter
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The effect of consumption volume on profile and liking of oral nutritional supplements of varied sweetness: sequential profiling and boredom tests
Oral nutrition supplements (ONS) are routinely prescribed to those with, or at risk of, malnutrition. Previous research identified poor compliance due to taste and sweetness. This paper investigates taste and hedonic liking of ONS, of varying sweetness and metallic levels, over consumption volume; an important consideration as patients are prescribed large volumes of ONS daily. A sequential descriptive profile was developed to determine the perception of sensory attributes over repeat consumption of ONS. Changes in liking of ONS following repeat consumption were characterised by a boredom test. Certain flavour (metallic taste, soya milk flavour) and mouthfeel (mouthdrying, mouthcoating) attributes built up over increased consumption volume (p 0.002). Hedonic liking data from two cohorts, healthy older volunteers (n = 32, median age 73) and patients (n = 28, median age 85), suggested such build-up was disliked. Efforts made to improve the palatability of ONS must take account of the build up of taste and mouthfeel characteristics over increased consumption volume
The RMS Survey: Resolving kinematic distance ambiguities towards a sample of compact HII regions using HI absorption
We present high-resolution HI data obtained using the Australia Telescope
Compact Array to resolve the near/far distance ambiguities towards a sample of
compact HII regions from the Red MSX Source (RMS) survey. The high resolution
data are complemented with lower resolution archival HI data extracted from the
Southern and VLA Galactic Plane surveys. We resolve the distance ambiguity for
nearly all of the 105 sources where the continuum was strong enough to allow
analysis of the HI absorption line structure. This represents another step in
the determination of distances to the total RMS sample, which with over 1,000
massive young stellar objects and compact HII regions, is the largest and most
complete sample of its kind. The full sample will allow the distribution of
massive star formation in the Galaxy to be examined.Comment: Accepted by MNRAS. This paper consists of 15 pages and contains 10
figures and 5 table
Substrate specificity and the effect of calcium on Trypanosomabrucei metacaspase 2
Metacaspases are cysteine peptidases found only in yeast, plants and lower eukaryotes, including the protozoa. To investigate the extended substrate specificity and effects of Ca<sup>2+</sup> on the activation of these enzymes, detailed kinetic, biochemical and structural analyses were carried out on metacaspase 2 from Trypanosoma brucei (TbMCA2). These results reveal that TbMCA2 has an unambiguous preference for basic amino acids at the P<sub>1</sub> position of peptide substrates and that this is most probably a result of hydrogen bonding from the P<sub>1</sub> residue to Asp95 and Asp211 in TbMCA2. In addition, TbMCA2 also has a preference for charged residues at the P<sub>2</sub> and P<sub>3</sub>positions and for small residues at the prime side of a peptide substrate. Studies into the effects of Ca<sup>2+</sup> on the enzyme revealed the presence of two Ca<sup>2+</sup> binding sites and a reversible structural modification of the enzyme upon Ca<sup>2+</sup> binding. In addition, the concentration of Ca<sup>2+</sup> used for activation of TbMCA2 was found to produce a differential effect on the activity of TbMCA2, but only when a series of peptides that differed in P<sub>2</sub> were examined, suggesting that Ca<sup>2+</sup>activation of TbMCA2 has a structural effect on the enzyme in the vicinity of the S2 binding pocket. Collectively, these data give new insights into the substrate specificity and Ca<sup>2+</sup> activation of TbMCA2. This provides important functional details and leads to a better understanding of metacaspases, which are known to play an important role in trypanosomes and make attractive drug targets due to their absence in humans
SERMeQ Model Produces a Realistic Upper Bound on Calving Retreat for 155 Greenland Outlet Glaciers
The rate of land ice loss due to iceberg calving is a key source of variability among model projections of the 21st century sea level rise. It is especially challenging to account for mass loss due to iceberg calving in Greenland, where ice drains to the ocean through hundreds of outlet glaciers, many smaller than typical model grid scale. Here, we apply a numerically efficient network flowline model (SERMeQ) forced by surface mass balance to simulate an upper bound on decadal calving retreat of 155 grounded outlet glaciers of the Greenland Ice Sheetâresolving five times as many outlets as was previously possible. We show that the upper bound holds for 91% of glaciers examined and that simulated changes in terminus position correlate with observed changes. SERMeQ can provide a physically consistent constraint on forward projections of the dynamic mass loss from the Greenland Ice Sheet associated with different climate projections.Key PointsWe test an upperâbound model of calving retreat of 155 oceanâterminating outlet glaciers that drain the Greenland Ice SheetOur physicsâbased method produces terminus positions that correlate with observed positions for 103 glaciers without model tuningOur model bounds retreat rates on 91% of glaciers tested, providing a constraint for future sea level projectionsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/3/grl61420-sup-0003-2020GL090213-Text_SI-S01.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/2/grl61420_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/1/grl61420.pd
Interferometric method for determining the sum of the flexoelectric coefficients (e1+e3) in an ionic nematic material
The time-dependent periodic distortion profile in a nematic liquid crystal phase grating has been measured from the displacement of tilt fringes in a Mach-Zehnder interferometer. A 0.2âHz squarewave voltage was applied to alternate stripe electrodes in an interdigitated electrode geometry. The time-dependent distortion profile is asymmetric with respect to the polarity of the applied voltage and decays with time during each half period due to ionic shielding. This asymmetry in the response allows the determination of the sum of the flexoelectric coefficients (e1+e3) using nematic continuum theory since the device geometry does not possess inherent asymmetry
Lowâtemperature crystallization of La0.15Sr0.775TiO3 using ionic liquids
The nâtype thermoelectric oxide La0.15Sr0.775TiO3 (LST) has been synthesized at 600°C using an ionic liquid method. The method uses the ionic liquid 1âethyl 3âmethylimidazolium acetate as the sole complexing agent: the lack of a second, carbonârich template decreases the quantity of reduced intermediate phases which form during heating. By suppressing these phases, greatly reduced temperatures can be used to crystallize the perovskite LST phase, on the nanoscale. These nanoparticles have the potential to be used to increase the figure of merit in nâtype thermoelectric oxide devices
Hele-Shaw flow of a nematic liquid crystal
Motivated by the variety of applications in which nematic Hele-Shaw flow
occurs, a theoretical model for Hele-Shaw flow of a nematic liquid crystal is
formulated and analysed. We derive the thin-film Ericksen-Leslie equations that
govern nematic Hele-Shaw flow, and consider two important limiting cases in
which we can make significant analytical progress. Firstly, we consider the
leading-order problem in the limiting case in which elasticity effects dominate
viscous effects, and find that the nematic liquid crystal anchoring on the
plates leads to a fixed director field and an anisotropic patterned viscosity
that can be used to guide the flow of the nematic. Secondly, we consider the
leading-order problem in the opposite limiting case in which viscous effects
dominate elasticity effects, and find that the flow is identical to that of an
isotropic fluid and the behaviour of the director is determined by the flow. As
an example of the insight which can be gained by using the present approach, we
then consider the flow of nematic according to a simple model for the squeezing
stage of the One Drop Filling method, an important method for the manufacture
of Liquid Crystal Displays, in these two limiting cases
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