ALMA CO J=6-5 observations of IRAS16293-2422: Shocks and entrainment

Observations of higher-excited transitions of abundant molecules such as CO are important for determining where energy in the form of shocks is fed back into the parental envelope of forming stars. The nearby prototypical and protobinary low-mass hot core, IRAS16293-2422 (I16293) is ideal for such a study. The source was targeted with ALMA for science verification purposes in band 9, which includes CO J=6-5 (E_up/k_B ~ 116 K), at an unprecedented spatial resolution (~0.2", 25 AU). I16293 itself is composed of two sources, A and B, with a projected distance of 5". CO J=6-5 emission is detected throughout the region, particularly in small, arcsecond-sized hotspots, where the outflow interacts with the envelope. The observations only recover a fraction of the emission in the line wings when compared to data from single-dish telescopes, with a higher fraction of emission recovered at higher velocities. The very high angular resolution of these new data reveal that a bow shock from source A coincides, in the plane of the sky, with the position of source B. Source B, on the other hand, does not show current outflow activity. In this region, outflow entrainment takes place over large spatial scales, >~ 100 AU, and in small discrete knots. This unique dataset shows that the combination of a high-temperature tracer (e.g., CO J=6-5) and very high angular resolution observations is crucial for interpreting the structure of the warm inner environment of low-mass protostars.Comment: Accepted for publication in A&A Letter

SERMeQ Model Produces a Realistic Upper Bound on Calving Retreat for 155 Greenland Outlet Glaciers

The rate of land ice loss due to iceberg calving is a key source of variability among model projections of the 21st century sea level rise. It is especially challenging to account for mass loss due to iceberg calving in Greenland, where ice drains to the ocean through hundreds of outlet glaciers, many smaller than typical model grid scale. Here, we apply a numerically efficient network flowline model (SERMeQ) forced by surface mass balance to simulate an upper bound on decadal calving retreat of 155 grounded outlet glaciers of the Greenland Ice Sheet—resolving five times as many outlets as was previously possible. We show that the upper bound holds for 91% of glaciers examined and that simulated changes in terminus position correlate with observed changes. SERMeQ can provide a physically consistent constraint on forward projections of the dynamic mass loss from the Greenland Ice Sheet associated with different climate projections.Key PointsWe test an upper‐bound model of calving retreat of 155 ocean‐terminating outlet glaciers that drain the Greenland Ice SheetOur physics‐based method produces terminus positions that correlate with observed positions for 103 glaciers without model tuningOur model bounds retreat rates on 91% of glaciers tested, providing a constraint for future sea level projectionsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/3/grl61420-sup-0003-2020GL090213-Text_SI-S01.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/2/grl61420_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163401/1/grl61420.pd

The RMS Survey: Resolving kinematic distance ambiguities towards a sample of compact HII regions using HI absorption

We present high-resolution HI data obtained using the Australia Telescope Compact Array to resolve the near/far distance ambiguities towards a sample of compact HII regions from the Red MSX Source (RMS) survey. The high resolution data are complemented with lower resolution archival HI data extracted from the Southern and VLA Galactic Plane surveys. We resolve the distance ambiguity for nearly all of the 105 sources where the continuum was strong enough to allow analysis of the HI absorption line structure. This represents another step in the determination of distances to the total RMS sample, which with over 1,000 massive young stellar objects and compact HII regions, is the largest and most complete sample of its kind. The full sample will allow the distribution of massive star formation in the Galaxy to be examined.Comment: Accepted by MNRAS. This paper consists of 15 pages and contains 10 figures and 5 table

The RMS Survey: Far-Infrared Photometry of Young Massive Stars

Context: The Red MSX Source (RMS) survey is a multi-wavelength campaign of follow-up observations of a colour-selected sample of candidate massive young stellar objects (MYSOs) in the galactic plane. This survey is returning the largest well-selected sample of MYSOs to date, while identifying other dust contaminant sources with similar mid-infrared colours including a large number of new ultra-compact (UC)HII regions. Aims:To measure the far-infrared (IR) flux, which lies near the peak of the spectral energy distribution (SED) of MYSOs and UCHII regions, so that, together with distance information, the luminosity of these sources can be obtained. Methods:Less than 50% of RMS sources are associated with IRAS point sources with detections at 60 micron and 100 micron, though the vast majority are visible in Spitzer MIPSGAL or IRAS Galaxy Atlas (IGA) images. However, standard aperture photometry is not appropriate for these data due to crowding of sources and strong spatially variable far-IR background emission in the galactic plane. A new technique using a 2-dimensional fit to the background in an annulus around each source is therefore used to obtain far-IR photometry for young RMS sources. Results:Far-IR fluxes are obtained for a total of 1113 RMS candidates identified as young sources. Of these 734 have flux measurements using IGA 60 micron and 100 micron images and 724 using MIPSGAL 70 micron images, with 345 having measurements in both data sets.Comment: 10 pages, 10 figures, 2 Tables, accepted to A&A. A full version of table 1 is available from the lead author or at the CDS upon publicatio

The RMS Survey: Ammonia and water maser analysis of massive star forming regions

The Red MSX Source (RMS) survey has identified a sample of ~1200 massive young stellar objects (MYSOs), compact and ultra compact HII regions from a sample of ~2000 MSX and 2MASS colour selected sources. We have used the 100 m Green Bank telescope to search for 22-24 GHz water maser and ammonia (1,1), (2,2) and (3,3) emission towards ~600 RMS sources located within the northern Galactic plane. We have identified 308 H2O masers which corresponds to an overall detection rate of ~50%. Abridged: We detect ammonia emission towards 479 of these massive young stars, which corresponds to ~80%. Ammonia is an excellent probe of high density gas allowing us to measure key parameters such as gas temperatures, opacities, and column densities, as well as providing an insight into the gas kinematics. The average kinetic temperature, FWHM line width and total NH3 column density for the sample are approximately 22 K, 2 km/s and 2x10^{15} cm^{-2}, respectively. We find that the NH3 (1,1) line width and kinetic temperature are correlated with luminosity and finding no underlying dependence of these parameters on the evolutionary phase of the embedded sources, we conclude that the observed trends in the derived parameters are more likely to be due to the energy output of the central source and/or the line width-clump mass relationship. The velocities of the peak H2O masers and the NH3 emission are in excellent agreement with each other, which would strongly suggest an association between the dense gas and the maser emission. Moreover, we find the bolometric luminosity of the embedded source and the isotropic luminosity of the H2O maser are also correlated. We conclude from the correlations of the cloud and water maser velocities and the bolometric and maser luminosity that there is a strong dynamical relationship between the embedded young massive star and the H2O maser.Comment: 17 pages and 17 figures and 8 tables. Tables\,2 and 5 and full versions of Figs. 3 and 7 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.125.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A

High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a

The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry. The rapid increase of resistance to therapeutic agents, as well as the expense of vaccination with live attenuated vaccines, requires the development of new effective treatments for coccidiosis. Because of their key regulatory function in the eukaryotic cell cycle, cyclin-dependent kinases (CDKs) are prominent drug targets. The Eimeria tenella CDC2-related kinase 2 (EtCRK2) is a validated drug target that can be activated in vitro by the CDK activator XlRINGO (Xenopus laevis rapid inducer of G2/M progression in oocytes). Bioinformatics analyses revealed four putative E. tenella cyclins (EtCYCs) that are closely related to cyclins found in the human apicomplexan parasite Plasmodium falciparum. EtCYC3a was cloned, expressed in Escherichia coli and purified in a complex with EtCRK2. Using the non-radioactive time-resolved fluorescence energy transfer (TR-FRET) assay, we demonstrated the ability of EtCYC3a to activate EtCRK2 as shown previously for XlRINGO. The EtCRK2/EtCYC3a complex was used for a combined in vitro and in silico high-throughput screening approach, which resulted in three lead structures, a naphthoquinone, an 8-hydroxyquinoline and a 2-pyrimidinyl-aminopiperidine-propane-2-ol. This constitutes a promising starting point for the subsequent lead optimization phase and the development of novel anticoccidial drugs

The RMS Survey: The Bolometric Fluxes and Luminosity Distributions of Young Massive Stars

Context: The Red MSX Source (RMS) survey is returning a large sample of massive young stellar objects (MYSOs) and ultra-compact (UC) \HII{} regions using follow-up observations of colour-selected candidates from the MSX point source catalogue. Aims: To obtain the bolometric fluxes and, using kinematic distance information, the luminosities for young RMS sources with far-infrared fluxes. Methods: We use a model spectral energy distribution (SED) fitter to obtain the bolometric flux for our sources, given flux data from our work and the literature. The inputs to the model fitter were optimised by a series of investigations designed to reveal the effect varying these inputs had on the resulting bolometric flux. Kinematic distances derived from molecular line observations were then used to calculate the luminosity of each source. Results: Bolometric fluxes are obtained for 1173 young RMS sources, of which 1069 have uniquely constrained kinematic distances and good SED fits. A comparison of the bolometric fluxes obtained using SED fitting with trapezium rule integration and two component greybody fits was also undertaken, and showed that both produce considerable scatter compared to the method used here. Conclusions: The bolometric flux results allowed us to obtain the luminosity distributions of YSOs and UC\HII{} regions in the RMS sample, which we find to be different. We also find that there are few MYSOs with L $\geq$ 10$^{5}$\lsol{}, despite finding many MYSOs with 10$^{4}$\lsol{} $\geq$ L $\geq$ 10$^{5}$\lsol{}.Comment: 12 pages, 12 figures, 3 tables, accepted to A&A. The full versions of tables 1 and 2 will be available via the CDS upon publicatio

ATLASGAL - towards a complete sample of massive star forming clumps

By matching infrared-selected, massive young stellar objects (MYSOs) and compact HII regions in the Red MSX Source survey to massive clumps found in the submillimetre ATLASGAL (APEX Telescope Large Area Survey of the Galaxy) survey, we have identified ~1000 embedded young massive stars between 280{ring operator} <lPeer reviewedFinal Accepted Versio