ArduImu: Unidad de medición inercial basada en arduino

[Resumen] El objetivo principal de este proyecto de fin de grado es realizar el diseño hardware y software, además de su posterior implementación de una unidad de medición inercial en arduino. Para cumplir ese objetivo principal establecimos algunos objetivos secundarios: • Crear el software para el control de la placa de arduino. • Interacción con un Imu a través de arduino. • Registro de datos en una tarjeta sd en arduino. • Crear una aplicación de escritorio para poder interactuar con arduino desde el pc. • La posibilidad de ver en tiempo real los movimientos del imu desde el pc. • Sincronización de un RTC con la hora del ordenador al que la placa arduino este conectada. • Visualización en el pc de los datos guardados en la tarjeta SD. • Establecer un modo sueño para que el sistema arduino consuma menos energía. Para poder cumplir estos objetivos necesitamos algunos componentes hardware: • Arduino MkrZero. • Una unidad de medición inercial. • Un RTC. • Un pulsador. • Tarjeta micro sd. A mayores de los objetivos anteriores hemos alcanzado otros según íbamos avanzando en el desarrollo del proyecto, como evitar que la interfaz de usuario se congelase al recibir datos desde arduino por el puerto serie y mostrarlos en la pantalla. Poder guardar datos en la sd para poder cargarlos en el arranque de la placa de arduino. El realizar este proyecto me ha permitido adquirir una serie de conocimientos que antes no tenía o aumentar los conocimientos ya existentes. Algunos de ellos fueron: conseguir como el hardware y el software se unan para trabajar juntos a la perfección y en total sincronía, como a un sistema hardware se le pueden añadir más elementos para poder crear un sistema más complejo. A parte de aprender a conectar hardware y software, he conocido otras formas de crear interfaces de usuario en java basadas en xml. Al tener que actualizar esa interfaz de usuario con datos que provenientes del puerto serie he tenido que usar threads para evitar que se congelara dicha interfaz. El desarrollo del proyecto se realizó con una metodología basada en scrum con sprints o iteraciones. Cada sprint constaba de diversas fases: análisis, diseño, implementación y pruebas. Algunas fases podían estar divididas en subfases, por ejemplo, diseño comprendía tres categorías: diseño hardware, diseño software y diseño de la interfaz de usuario. Destacar que este proyecto se realizó para poder observar los movimientos de un objeto que realiza en una superficie, aunque puede tener otros usos. Ya que actualmente las unidades de medición inerciales las encontramos en cualquier sitio, incluso en nuestros móviles, drones, etc. Para finalizar este resumen, decir que este proyecto solo araña una parte de lo que se puede hacer con una placa de arduino, porque a pesar de haberlo finalizado, aún se pueden realizar muchas mejoras, una de ellas sería conectar la placa a internet, para poder obtener los datos de manera remota sin tener que acercarnos al lugar donde este y poder guardar los datos en un servidor u otro dispositivo remoto, ya que la memoria de la tarjeta sd es más limitada.[Abstract] The main objective of this end-of-grade project is to carry out the hardware and software design, as well as the subsequent implementation of an arduino based inertial measurement unit. In order to achieve this main objective, we established some secondary objectives: • Create the software for the control of the arduino board • Interaction with an Imu through arduino. • Data logging on an sd card in arduino. • Create a desktop application to be able to interact with arduino from the pc • The possibility to see in real time the movements of the imu from the pc. • Synchronization of a RTC with the time of the computer to which arduino is connected. • Visualization in the pc of the data saved in SD. • Establish a sleep mode so that the arduino system consumes less energy. In order to meet these objectives we need some hardware components: • Arduino MkrZero • A inertial measuring unit. • A RTC. • A pushbutton. • Micro sd card. In addition to the above objectives, we achieved others as we progressed in the development of the project, such as preventing the user interface from freezing when receiving data from arduino through the serial port and displaying it on the screen. To be able to save data in the sd to be able to load them in the start of the arduino board. This project has allowed me to acquire a series of knowledge that I did not have before or increase the existing knowledge. Some of them were: to get as the hardware and the software unite to work together to the perfection and in total synchrony, as to a hardware system more elements can be added to him to be able to create a more complex system. Apart from learning to connect hardware and software, I have known other ways to create user interfaces in java based on xml.Having to update that user interface with data from the serial port, I had to use threads to avoid freezing that interface. The development of the project was done with a scrum-based methodology with sprints or iterations. Each sprint consisted of several phases: analysis, design, implementation and testing. This phases could be divided into subphases, for example, design comprised two categories: hardware design and software design. To end this summary, say that this project only scratches a part of what can be done with an arduino board, because despite having finished, many improvements can still be made, one of them would be to connect the board to the Internet and be able to obtain data remotely without having to go near the place where it is and be able to save the data on a server or other remote device because the memory of the sd card is more limited.Traballo fin de grao (UDC.FIC). Enxeñaría informática. Curso 2018/201

Matching microscopic and macroscopic responses in glasses

Primero reproducimos en las computadoras Janus y Janus II un experimento importante que mide la longitud de la coherencia de los hilados de vidrio a través de la reducción de las barreras de energía libre inducidas por el efecto Zeeman. En segundo lugar, determinamos el comportamiento de escala que permite un análisis cuantitativo de un nuevo experimento informado en la Carta complementaria [S. Guchhait y R. Orbach, Phys. Rev. Lett. 118, 157203 (2017)]. El valor de la longitud de coherencia estimada a través del análisis de las funciones de correlación microscópicas resulta ser cuantitativamente consistente con su medición a través de las funciones de respuesta macroscópica. Además, las susceptibilidades no lineales, recientemente medidas en líquidos formadores de vidrio, se escalan como potencias de la misma longitud microscópica.We first reproduce on the Janus and Janus II computers a milestone experiment that measures the spin glass coherence length through the lowering of free-energy barriers induced by the Zeeman effect. Secondly, we determine the scaling behavior that allows a quantitative analysis of a new experiment reported in the companion Letter [S. Guchhait and R. Orbach, Phys. Rev. Lett. 118, 157203 (2017)]. The value of the coherence length estimated through the analysis of microscopic correlation functions turns out to be quantitatively consistent with its measurement through macroscopic response functions. Further, nonlinear susceptibilities, recently measured in glass-forming liquids, scale as powers of the same microscopic length.• European Research Council. Beca No. NPRGGLASS. Ayuda para Marco Baity Jesi • Unión Europea. Marie Skłodowska- Curie. Beca No. 654971 • Consejo Europeo de Investigación (ERC). Subvención 694925 • University of Syracuse. Beca No. NSF-DMR-305184, para David Yllanes Mosquera • Ministerio de Economía y Competitividad. No. FIS2012-35719-C02, No. FIS2013-42840-P (I+D+i), No. FIS2015-65078-C2, No. FIS2016-76359-P (I+D+i), y No. TEC2016-78358-R • Junta de Extremadura y Fondos FEDER. Contrato parcial GRU10158 • Dipùtación General de Aragón y Fondos Social Europeo. AyudapeerReviewe

Proceso asistencial integrado de esclerosis lateral amiotrófica

O proceso asistencial integrado da esclerose lateral amiotrófica, elaborouse co obxectivo de crear un proceso de traballo común en todas as áreas para facilitar a asistencia sanitaria ás persoas diagnosticadas desta enfermidade. Establécense actuacións como o asesoramento continuo, as consultas en acto único, a coordinación asistencial, tanto entre especialidades como coa atención primaria e a coordinación administrativa do sistema socio sanitario. Neste proceso participaron profesionais das diferentes áreas sanitarias especialistas en neuroloxía, endocrinoloxía, neumoloxía, psicoloxía clínica, rehabilitación, traballo social e hospitalización a domicilioEl proceso asistencial integrado de la esclerosis lateral amiotrófica, se elaboró con el objetivo de crear un proceso de trabajo común en todas las áreas para facilitar la asistencia sanitaria a las personas diagnosticadas de esta enfermedad. Se establecen actuaciones como el asesoramiento continuo, las consultas en acto único, la coordinación asistencial, tanto entre especialidades como con la atención primaria y la coordinación administrativa del sistema socio sanitario. En este proceso participaron profesionales de las diferentes áreas sanitarias especialistas en neurología, endocrinología, neumología, psicología clínica, rehabilitación, trabajo social y hospitalización a domicili

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The 'omics' approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A combination of three lipids achieved an area under the receiver operating characteristic (ROC) curve of 0.911 (95% CI 0.81 to 0.98). This pilot study demonstrates the potential of metabolic biomarkers to assist clinicians in distinguishing bacterial from viral infection in febrile children, to facilitate effective clinical management and to the limit inappropriate use of antibiotics

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar

Genomic investigations of unexplained acute hepatitis in children

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK1. Here we report an investigation of 38 cases, 66 age-matched immunocompetent controls and 21 immunocompromised comparator participants, using a combination of genomic, transcriptomic, proteomic and immunohistochemical methods. We detected high levels of adeno-associated virus 2 (AAV2) DNA in the liver, blood, plasma or stool from 27 of 28 cases. We found low levels of adenovirus (HAdV) and human herpesvirus 6B (HHV-6B) in 23 of 31 and 16 of 23, respectively, of the cases tested. By contrast, AAV2 was infrequently detected and at low titre in the blood or the liver from control children with HAdV, even when profoundly immunosuppressed. AAV2, HAdV and HHV-6 phylogeny excluded the emergence of novel strains in cases. Histological analyses of explanted livers showed enrichment for T cells and B lineage cells. Proteomic comparison of liver tissue from cases and healthy controls identified increased expression of HLA class 2, immunoglobulin variable regions and complement proteins. HAdV and AAV2 proteins were not detected in the livers. Instead, we identified AAV2 DNA complexes reflecting both HAdV-mediated and HHV-6B-mediated replication. We hypothesize that high levels of abnormal AAV2 replication products aided by HAdV and, in severe cases, HHV-6B may have triggered immune-mediated hepatic disease in genetically and immunologically predisposed children

High-Sustained Concentrations of Organisms at Very low Oxygen Concentration Indicated by Acoustic Profiles in the Oxygen Deficit Region Off Peru

International audienceThe oxygen deficient mesopelagic layer (ODL) off Peru has concentrations below 5 μmol O 2 kg –1 and is delimited by a shallow upper oxycline with strong vertical gradient and a more gradual lower oxycline ( lOx ). Some regions show a narrow band of slightly increased oxygen concentrations within the ODL, an intermediate oxygen layer ( iO 2 ). CTD, oxygen and lowered Acoustic Doppler Current Profiler (LADCP, 300 kHz) profiles were taken on the shelf edge and outside down to mostly 2000 m. We evaluate here the acoustic volume backscatter strength of the LADCP signal representing organisms of about 5 mm size. Dominant features of the backscatter profiles were a minimum backscatter strength within the ODL, and just below the lOx a marked backscatter increase reaching a maximum at less than 3.0 μmol O 2 kg –1 . Below this maximum, the acoustic backscatter strength gradually decreased down to 1000 m below the lOx . The backscatter strength also increased at the iO 2 in parallel to the oxygen concentration perturbations marking the iO 2 . These stable backscatter features were independent of the time of day and the organisms represented by the backscatter had to be adapted to live in this microaerobic environment. During daylight, these stable structures were overlapped by migrating backscatter peaks. Outstanding features of the stable backscatter were that at very low oxygen concentrations, the volume backscatter was linearly related to the oxygen concentration, reaching half peak maximum at less than 2.0 μmol O 2 kg –1 below the lOx , and the depth-integrated backscatter of the peak below the lOx was higher than the integral above the Ox. Both features suggest that sufficient organic material produced at the surface reaches to below the ODL to sustain the major fraction of the volume backscatter-producing organisms in the water column. These organisms are adapted to the microaerobic environment so they can position themselves close to the lower oxycline to take advantage of the organic particles sinking out of the ODL

High-Sustained Concentrations of Organisms at Very low Oxygen Concentration Indicated by Acoustic Profiles in the Oxygen Deficit Region Off Peru

The oxygen deficient mesopelagic layer (ODL) off Peru has concentrations below 5 μmol O2 kg–1 and is delimited by a shallow upper oxycline with strong vertical gradient and a more gradual lower oxycline (lOx). Some regions show a narrow band of slightly increased oxygen concentrations within the ODL, an intermediate oxygen layer (iO2). CTD, oxygen and lowered Acoustic Doppler Current Profiler (LADCP, 300 kHz) profiles were taken on the shelf edge and outside down to mostly 2000 m. We evaluate here the acoustic volume backscatter strength of the LADCP signal representing organisms of about 5 mm size. Dominant features of the backscatter profiles were a minimum backscatter strength within the ODL, and just below the lOx a marked backscatter increase reaching a maximum at less than 3.0 μmol O2 kg–1. Below this maximum, the acoustic backscatter strength gradually decreased down to 1000 m below the lOx. The backscatter strength also increased at the iO2 in parallel to the oxygen concentration perturbations marking the iO2. These stable backscatter features were independent of the time of day and the organisms represented by the backscatter had to be adapted to live in this microaerobic environment. During daylight, these stable structures were overlapped by migrating backscatter peaks. Outstanding features of the stable backscatter were that at very low oxygen concentrations, the volume backscatter was linearly related to the oxygen concentration, reaching half peak maximum at less than 2.0 μmol O2 kg–1 below the lOx, and the depth-integrated backscatter of the peak below the lOx was higher than the integral above the Ox. Both features suggest that sufficient organic material produced at the surface reaches to below the ODL to sustain the major fraction of the volume backscatter-producing organisms in the water column. These organisms are adapted to the microaerobic environment so they can position themselves close to the lower oxycline to take advantage of the organic particles sinking out of the ODL