Emigrating from the state school to a public one. A case study on an inclusive school.

Con el presente Trabajo de Fin de Grado pretendemos iniciarnos en la investigación educativa. Después de observar que muchas de las familias del centro en el qu e nos encontrábamos de prácticas se desplazaban desde muy lejos, incluso desde otras provincias, nos interesamos por conocer, comprender y analiz ar qué motivaba esta decisión. Elegimos l a investigación etnográfica con estudio de caso, pues consideramos que era la más coherente con nuestro propósito al permiti rnos adentrarnos en lo particular y único de una realidad concreta. Nuestra condición de alumnos que repetían periodo de prácticas por segundo año consecutivo nos colocaba en una posición inmejorable pa ra realizar este tipo de investigación. El estudio se ha realiza do en torno a un pequeño Colegio Público de Educación Infantil y Primaria, para el cual utilizamos una serie de instrumentos y técnicas tales como: entrevistas, cuestionarios, análisis de docu mento y observación participante. De los datos recogidos se deduce que las familias vienen al centro buscando un modelo de escuela alternativo, algunas de ellas en respuesta a la violencia ejercida hacia sus hijos y sus hijas en la escuela de origen. En la elección se valora especialmente elementos cognitivos como qué y cómo se enseña; así como otros de del ámbito de lo afectivo como puedan ser las relaciones que se generan y los valores que se viven, especialmente la participación, la cooperación y el resp eto al medio ambiente

Mechanisms of Action of Non-Canonical ECF Sigma Factors

Extracytoplasmic function (ECF) sigma factors are subunits of the RNA polymerase specialized in activating the transcription of a subset of genes responding to a specific environmental condition. The signal-transduction pathways where they participate can be activated by diverse mechanisms. The most common mechanism involves the action of a membrane-bound anti-sigma factor, which sequesters the ECF sigma factor, and releases it after the stimulus is sensed. However, despite most of these systems following this canonical regulation, there are many ECF sigma factors exhibiting a non-canonical regulatory mechanism. In this review, we aim to provide an updated and comprehensive view of the different activation mechanisms known for non-canonical ECF sigma factors, detailing their inclusion to the different phylogenetic groups and describing the mechanisms of regulation of some of their representative members such as EcfG from Rhodobacter sphaeroides, showing a partner-switch mechanism; EcfP from Vibrio parahaemolyticus, with a phosphorylation-dependent mechanism; or CorE from Myxococcus xanthus, regulated by a metal-sensing C-terminal extension.Spanish Government (PID2020-112634GB-I00)FEDER funds (grant A-BIO-126-UGR20

MEPSA: Minimum energy pathway analysis for energy landscapes

From conformational studies to atomistic descriptions of enzymatic reactions, potential and free energy landscapes can be used to describe biomolecular systems in detail. However, extracting the relevant data of complex 3D energy surfaces can sometimes be laborious. In this article, we present MEPSA (Minimum Energy Path Surface Analysis), a cross-platform user friendly tool for the analysis of energy landscapes from a transition state theory perspective. Some of its most relevant features are: identification of all the barriers and minima of the landscape at once, description of maxima edge profiles, detection of the lowest energy path connecting two minima and generation of transition state theory diagrams along these paths. In addition to a built-in plotting system, MEPSA can save most of the generated data into easily parseable text files, allowing more versatile uses of MEPSA's output such as the generation of molecular dynamics restraints from a calculated path.Grant IPT2011-0964-900000 (Government of Spain).Peer Reviewe

Implementación de un sistema de posicionamiento vehicular utilizando tecnologías GPS y GLONASS.

Presenta un sistema de posicionamiento que integre las tecnologías GPS/GLONASS para la ubicación, seguimiento y monitoreo de vehículos

Biometric database acquisition close to “Real World” conditions

The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-12397-9_16Revised Selected Papers of Second COST 2102 International Training School, Dublin, Ireland, March 23-27, 2009In this paper we present an autonomous biometric device developed in the framework of a national project. This system is able to capture speech, hand-geometry, online signature and face, and can open a door when the user is positively verified. Nevertheless the main purpose is to acquire a database without supervision (normal databases are collected in the presence of a supervisor that tells you what to do in front of the device, which is an unrealistic situation). This system will permit us to explain the main differences between what we call "real conditions" as opposed to "laboratory conditions".This work has been supported by FEDER and MEC, TEC2006-13141-C03/TCM, and COST-210

A novel inlet boundary condition for VOF-DNS simulations of the primary breakup of prefilming airblast atomizers

[Otros] Prefilming airblast atomizers are becoming widely used in state-of-the-art aero engines. The planar configuration experimentally studied by the Karlsruhe Institute of Technology (KIT) has been computationally replicated by different research groups through both Large Eddy Simulation (LES) and Direct Numerical Simulation (DNS). The present investigation reports the use of a novel inlet boundary condition for the DNS study of prefilming airblast atomization that allows accounting not only for the inflow turbulence but also for the temporal evolution of the liquid film thickness at the DNS inlet. The methodology implies the resolution of subsequent singlephase LES, two-phase flow LES and two-phase flow DNS. The former simulations are solved by using the interFoam solver from the OpenFoam toolbox, whereas the latter is computed with the PARIS open-source code. Results for a widely known operating condition show a different degree of atomization when the liquid film thickness evolution is accounted for than the one obtained through the use of a constant liquid film thickness at the domain inlet.Research leading to these results has received funding from the Clean Sky 2 Joint Undertaking under European Union¿s Horizon 2020 research and innovation programme through the ESTiMatE project, grant agreement 821418. We acknowledge PRACE for awarding us access to computational resources on JOLIOT CURIE-AMD at GENCI@CEA, France (proposal 2019204944). Support given to Carlos Moreno by Universitat Politècnica de València through the ¿FPI-Subprograma 2¿ grant within the ¿Programa de Apoyo para la Investigación y Desarrollo (PAID-01-19)¿ is acknowledged. We must thank Marco Crialesi and Wojciech Aniszewski for their technical advice on custom modifications on PARIS, and Johan Sundin for his implementation of the contact angle model. We also thank Achille Schmitter, Hugo Martínez and Lucas González for help processing the 1-phase LES, 2-phase LES and DNS, respectively.Payri, R.; Salvador, FJ.; Carreres, M.; Moreno-Montagud, C. (2021). A novel inlet boundary condition for VOF-DNS simulations of the primary breakup of prefilming airblast atomizers. 1-8. http://hdl.handle.net/10251/173213S1

Fully automatic segmentation and monitoring of choriocapillaris flow voids in OCTA images

Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG.[Abstract]: Optical coherence tomography angiography (OCTA) is a non-invasive ophthalmic imaging modality that is widely used in clinical practice. Recent technological advances in OCTA allow imaging of blood flow deeper than the retinal layers, at the level of the choriocapillaris (CC), where a granular image is obtained showing a pattern of bright areas, representing blood flow, and a pattern of small dark regions, called flow voids (FVs). Several clinical studies have reported a close correlation between abnormal FVs distribution and multiple diseases, so quantifying changes in FVs distribution in CC has become an area of interest for many clinicians. However, CC OCTA images present very complex features that make it difficult to correctly compare FVs during the monitoring of a patient. In this work, we propose fully automatic approaches for the segmentation and monitoring of FVs in CC OCTA images. First, a baseline approach, in which a fully automatic segmentation methodology based on local contrast enhancement and global thresholding is proposed to segment FVs and measure changes in their distribution in a straightforward manner. Second, a robust approach in which, prior to the use of our segmentation methodology, an unsupervised trained neural network is used to perform a deformable registration that aligns inconsistencies between images acquired at different time instants. The proposed approaches were tested with CC OCTA images collected during a clinical study on the response to photodynamic therapy in patients affected by chronic central serous chorioretinopathy (CSC), demonstrating their clinical utility. The results showed that both approaches are accurate and robust, surpassing the state of the art, therefore improving the efficacy of FVs as a biomarker to monitor the patient treatments. This gives great potential for the clinical use of our methods, with the possibility of extending their use to other pathologies or treatments associated with this type of imaging.Xunta de Galicia; ED481B-2021-059Xunta de Galicia; ED431C 2020/24Xunta de Galicia; IN845D 2020/38Xunta de Galicia; ED431G 2019/01This research was funded by Instituto de Salud Carlos III, Government of Spain, DTS18/00136 research project; Ministerio de Ciencia e Innovación y Universidades, Government of Spain, RTI2018-095894-B-I00 research project; Ministerio de Ciencia e Innovación, Government of Spain through the research projects with references PID2019-108435RB-I00; TED2021-131201B-I00 and PDC2022-133132-I00; Consellería de Cultura, Educación e Universidade, Xunta de Galicia through the postdoctoral, grant ref. ED481B-2021-059; and Grupos de Referencia Competitiva, grant ref. ED431C 2020/24; Axencia Galega de Innovación (GAIN), Xunta de Galicia, grant ref. IN845D 2020/38; CITIC, as Research Center accredited by Galician University System, is funded by “Consellería de Cultura, Educación e Universidade from Xunta de Galicia”, supported in an 80 % through ERDF Funds, ERDF Operational Programme Galicia 2014–2020, and the remaining 20 % by “Secretaría Xeral de Universidades”, grant ref. ED431G 2019/01. Emilio López Varela acknowledges its support under FPI Grant Program through PID2019-108435RB-I00 project. Funding for open access charge: Universidade da Coruña/CISUG

Biometric system verification close to "real world" conditions

The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-04391-8_31Proceedings of Joint COST 2101 and 2102 International Conference, BioID_MultiComm 2009, Madrid, Spain.In this paper we present an autonomous biometric device developed in the framework of a national project. This system is able to capture speech, hand-geometry, online signature and face, and can open a door when the user is positively verified. Nevertheless the main purpose is to acquire a database without supervision (normal databases are collected in the presence of a supervisor that tells you what to do in front of the device, which is an unrealistic situation). This system will permit us to explain the main differences between what we call "real conditions" as opposed to "laboratory conditions".This work has been supported by FEDER and MEC, TEC2006-13141-C03/TCM, and COST-2102

Myxococcus xanthus predation: an updated overview

Bacterial predators are widely distributed across a variety of natural environments. Understanding predatory interactions is of great importance since they play a defining role in shaping microbial communities in habitats such as soils. Myxococcus xanthus is a soil-dwelling bacterial predator that can prey on Gram-positive and Gram-negative bacteria and even on eukaryotic microorganisms. This model organism has been studied for many decades for its unusual lifecycle, characterized by the formation of multicellular fruiting bodies filled with myxospores. However, less is known about its predatory behavior despite being an integral part of its lifecycle. Predation in M. xanthus is a multifactorial process that involves several mechanisms working synergistically, including motility systems to efficiently track and hunt prey, and a combination of short-range and contact-dependent mechanisms to achieve prey death and feed on them. In the short-range attack, M. xanthus is best known for the collective production of secondary metabolites and hydrolytic enzymes to kill prey and degrade cellular components. On the other hand, contact-dependent killing is a cell-to-cell process that relies on Tad-like and type III secretion systems. Furthermore, recent research has revealed that metals also play an important role during predation, either by inducing oxidative stress in the prey, or by competing for essential metals. In this paper, we review the current knowledge about M. xanthus predation, focusing on the different mechanisms used to hunt, kill, and feed on its prey, considering the most recent discoveries and the transcriptomic data available

Ocular surface analysis and automatic non-invasive assessment of tear film breakup location, extension and progression in patients with glaucoma

Background: Tear film stability is the key event in ocular surface diseases. The purpose of this study is to evaluate spatial and temporal progression of the tear film breakup using an automatic non-invasive device. Methods: Non-invasive tear breakup time (NITBUT) parameters, such as First NITBUT (F-NITBUT) and Average NITBUT (A-NITBUT), were evaluated in 132 glaucoma and 87 control eyes with the Keratograph 5 M device. Further analysis of this data was used to determine size, location and progression of tear film breakup with automatically identified breakup areas (BUA). The progression from First BUA (F-BUA) to total BUA (T-BUA) was expressed as Dry Area Growth Rate (DAGR). Differences between both groups were analysed using Student t-test for parametric data and Mann-Whitney U test for non-parametric data. Pearson’s correlation coefficient was used to assess the relationship between parametric variables and Spearman in the case of non-parametric variables. Results: F-NITBUT was 11.43 ± 7.83 s in the control group and 8.17 ± 5.73 in the glaucoma group (P = 0.010). A-NITBUT was 14.04 ± 7.21 and 11.82 ± 6.09 s in control and glaucoma groups, respectively (P = 0.028). F-BUA was higher in the glaucoma group than in the control group (2.73 and 2.28; P = 0.022) and was more frequently located at the centre of the cornea in the glaucoma group (P = 0.039). T-BUA was also higher in the glaucoma group than in the control group (13.24 and 9.76%; P = 0.012) and the DAGR was steeper in the glaucoma group than in the control group (34.38° and 27.15°; P = 0.009). Conclusions: Shorter NITBUT values and bigger, more central tear film breakup locations were observed in the glaucoma group than in the control group. The DAGR indicates that tear film rupture is bigger and increases faster in glaucomatous eyes than in normal eyes