Optimization of a portable NIR device for the optical supervision of milk coagulation process

The coagulation of milk is the fundamental process in cheese-making, which is based on a gel formation as consequence of physicochemical changes taking place in the casein micelles. Monitoring the whole process of milk curd formation is a dedicated process for dairy researchers and cheese companies. In addition to advances in composition-based applications by means of NIR spectroscopy, researchers are pursuing dynamic applications that show promise especially with regard to tracking a sample in situ during processing The objective of this work is to propose an original portable NIR equipment to supervise the milk coagulation process. The experiments have been carried out on sheep and goat milk, by immersion of the probe directly in the liquid and acquiring spectrum each 1 minute during the 30 minutes of coagulation process. The increasing values of transflected light registered allow identifying, based on PCA analysis, the different kinetics that occur along the gel formation and the time to reach the optimal gel firmness to cut the cur

Color Engineering of Silicon Nitride Surfaces to Characterize the Polydopamine Refractive Index

A simple methodology to generate polydopamine (PDA) surfaces featured with color due to thin-film interference phenomena is presented. It is based on depositing ultra-thin films of polydopamine on a Si/Si 3 N 4 wafer that exhibits an interferential reflectance maximum right at the visible/UV boundary (∼400 nm). Therefore, a small deposit of PDA modifies the optical path, in such manner that the wavelength of the maximum of reflectance red shifts. Because the human eye is very sensitive to any change of the light spectral distribution at the visible region, very small film thickness changes (∼30 nm) are enough to notably modify the perceived color. Consequently, a controlled deposit of PDA, tune the color along the whole visible spectrum. Additionally, good quality of PDA deposits allowed us to determine the refractive index of polydopamine by ellipsometry spectroscopy. This data can be crucial in confocal skin microscopic techniques, presently used in diagnosis of skin tumors.Fil: Vega Moreno, Milena Amparo. Universidad de Salamanca; EspañaFil: Martín del Valle, Eva M.. Universidad de Salamanca; EspañaFil: Perez, Maximiliano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; ArgentinaFil: Pecharromán, Carlos. Consejo Superior de Investigaciones Científicas. Instituto de Ciencia de los Materiales de Barcelona; EspañaFil: Marcelo, Gema. Universidad de Salamanca; Españ

Automatic domain-specific learning: towards a methodology for ontology enrichment

[EN] At the current rate of technological development, in a world where enormous amount of data are constantly created and in which the Internet is used as the primary means for information exchange, there exists a need for tools that help processing, analyzing and using that information. However, while the growth of information poses many opportunities for social and scientific advance, it has also highlighted the difficulties of extracting meaningful patterns from massive data. Ontologies have been claimed to play a major role in the processing of large-scale data, as they serve as universal models of knowledge representation, and are being studied as possible solutions to this. This paper presents a method for the automatic expansion of ontologies based on corpus and terminological data exploitation. The proposed ¿ontology enrichment method¿ (OEM) consists of a sequence of tasks aimed at classifying an input keyword automatically under its corresponding node within a target ontology. Results prove that the method can be successfully applied for the automatic classification of specialized units into a reference ontology.Financial support for this research has been provided by the DGI, Spanish Ministry of Education and Science, grant FFI2011-29798-C0201.Ureña Gómez-Moreno, P.; Mestre-Mestre, EM. (2017). Automatic domain-specific learning: towards a methodology for ontology enrichment. LFE. Revista de Lenguas para Fines Específicos. 23(2):63-85. http://hdl.handle.net/10251/148357S638523

Personality and mental health: the moderator role of emotional intelligence

This study analyze the role of emotional intelligence (EI) [attention to feelings (AF), emotional clarity (EC) and emotional repair (ER)] in the relationship between personality and mental health. The sample is composed of a total of 232 students of degree in early childhood and elementary education. The results show that neuroticism (N), agreeableness (A), attention to feeling (AF) and emotional repair (ER) are key to preventing stress, anxiety and depression. Emotional Clarity (EC) in stress and depression, and extraversion (E) and consciousness (C) in depression. Moreover, when the moderating role of EI in the relationship between personality traits and mental health was analysed, the results showed that he role of EI by itself does not buffer the detrimental effects of neuroticism (N) on mental health. EI might be more beneficial to the mental health of women with personality traits of extraversion (E), openness (O) and consciousness (C), and men with agreeableness (A) personality trait. Although these data are inconclusive, and more studies are needed to examine these relationships

Canine Epithelial Skin Tumours: Expression of the Stem Cell Markers Lgr5, Lgr6 and Sox9 in Light of New Cancer Stem Cell Theories.

Evidence is accumulating that tumour development is driven by cancer stem cells (CSCs). In order to understand the presence and potential contribution of stem cells (SCs) as tumour-initiating cells in canine cutaneous tumours, we selected three putative SC markers (Lgr5, Lgr6 and Sox9) and investigated their expression pattern, level of protein and mRNA expression, in 43 canine hair follicle (HF) and 18 canine cutaneous epidermal tumours by immunohistochemistry and qRT-PCR, using normal skin samples as controls. Lgr5 protein expression was not detected in epidermal and HF tumours; however, Lgr5 mRNA overexpression was evident in some HF tumours. Sox9 was expressed in several tumour cases, both at the protein and mRNA level. The Lgr6 antibody tested was not suitable for formalin-fixed paraffin-embedded tissue samples, but Lgr6 gene showed higher expression in several samples of both HF and epidermal tumours compared with normal skin. Significantly higher mRNA expression levels of the three SC markers were found in trichoblastomas (TB) compared with basal cell carcinomas (BCC). The present results indicated that canine HF and epidermal tumours might have common tumour-initiating cells. The mRNA expression of the three selected SC markers, especially Lgr5, could be potentially useful in the distinction between canine TB and BCC

Preliminary assessment of terrestrial microalgae isolated from lichens as testing species for environmental monitoring: Lichen phycobionts present high sensitivity to environmental micropollutants

Bioassays constitute a tool for pollution analysis providing a holistic approach and high-quality indication of the toxicity. Microbioassays allow evaluating the toxicity of many samples, implying lower costs and enabling routine monitoring and pollution control. But tests conducted so far are limited to the use of a small number of taxa. Lichens are excellent bioindicators of pollution with great ecological significance. Studies show that the phycobiont is more sensitive to pollutants than the mycobiont. Phycobiont have features such as adaptation to anhydrobiosis and relatively rapid growth in vitro, making them suitable for microbioassays. Our aim is to determine the sensitivity of phycobionts to the pharmaceutical micropollutants carbamazepine and diclofenac as a preliminary step for the development of a toxicity microbioassay based on phycobionts. Optical dispersion and chlorophyll autofluorescence were used as endpoints of toxicity on two algal species showing that suspensions present cyclic and taxon specific patterns of aggregation. Trebouxia TR9 suspensions present a very high grade of aggregation while Asterochloris erici cells do not. Both micropollutants alter optical properties of the suspensions of both species. No significant alteration of chlorophyll autofluorescence by carbamazepine is observed. A. erici chlorophyll autofluorescence is extremely sensitive to diclofenac but the effect is not dependent on the drug concentration or on the time of exposure. Differently, TR9 only shows punctual chlorophyll alterations. Fluctuations in optical dispersion may indicate changes in the population structure of the species, including reproductive strategy. A. erici seems more sensitive to micropollutants, is better characterized and is available from commercial collections

Creativity, art and laterality as tools for learning the language in children

The first years of life are fundamental because is the time where the bases are laid for the acquisition of cognitive skills, such as psychomotor, emotional and social abilities necessary for the proper learning. However, each day it is more common to find children in primary schools who suffer school failure. Behind this fact we find difficulties that have not been perceived in the first years of schooling, such as a poor integration of the body scheme and spatio-temporal orientation and a lack of definition in laterality. Different studies have shown that good laterality settlement can improve the literacy learning. Creativity, helps learning to be attached by a sense of pleasure which allows the development of cognitive, psychomotor, affective and social abilities in students. This study tests the influence of creativity, art and laterality in the learning of the language subject of 2nd grade children. 60 children have been gathered between the ages of 7 and 8 years old from Barcelona. The results of the investigation have shown that the defined laterality (right and left handed) favors the learning of the language subject to a greater extent than when it is crossed; meaning that academic performance is significantly higher when we have a defined laterality. In order to improve learning, an intervention is proposed to develop creativity and laterality, which is why this research has a preventive function of school failure

Clustering of energy balance-related behaviors and parental education in European children : the ENERGY-project

Background:Recent research and literature reviews show that, among schoolchildren, some specific energy balance-related behaviors (EBRBs) are relevant for overweight and obesity prevention. It is also well known that the prevalence of overweight and obesity is considerably higher among schoolchildren from lower socio-economic backgrounds. This study examines whether sugared drinks intake, physical activity, screen time and usual sleep duration cluster in reliable and meaningful ways among European children, and whether the identified clusters could be characterized by parental education. Methods: The cross-sectional study comprised a total of 5284 children (46% male), from seven European countries participating in the ENERGY-project ("EuropeaN Energy balance Research to prevent excessive weight Gain among Youth"). Information on sugared drinks intake, physical activity, screen time and usual sleep duration was obtained using validated self-report questionnaires. Based on these behaviors, gender-specific cluster analysis was performed. Associations with parental education were identified using chi-square tests and odds ratios. Results: Five meaningful and stable clusters were found for both genders. The cluster with high physical activity level showed the highest proportion of participants with highly educated parents, while clusters with high sugared drinks consumption, high screen time and low sleep duration were more prevalent in the group with lower educated parents. Odds ratio showed that children with lower educated parents were less likely to be allocated in the active cluster and more likely to be allocated in the low activity/sedentary pattern cluster. Conclusions: Children with lower educated parents seemed to be more likely to present unhealthier EBRBs clustering, mainly characterized by their self-reported time spent on physical activity and screen viewing. Therefore, special focus should be given to lower educated parents and their children in order to develop effective primary prevention strategies

E-cadherin expression is associated with somatostatin analogue response in acromegaly

Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs) represent the primary medical therapy for acromegaly and are currently used as first‐line treatment or as second‐line therapy after unsuccessful pituitary surgery. However, a considerable proportion of patients do not adequately respond to SSAs treatment, and therefore, there is an urgent need to identify biomarkers predictors of response to SSAs. The aim of this study was to examine E‐cadherin expression by immunohistochemistry in fifty‐five GH‐producing pituitary tumours and determine the potential association with response to SSAs as well as other clinical and histopathological features. Acromegaly patients with tumours expressing low E‐cadherin levels exhibit a worse response to SSAs. E‐cadherin levels are associated with GH‐producing tumour histological subtypes. Our results indicate that the immunohistochemical detection of E‐cadherin might be useful in categorizing acromegaly patients based on the response to SSAs.ISCIII‐Subdirección General de Evaluación y Fomento de la Investigación PI13/02043 PI16/00175FEDER PI13/02043 PI16/00175Junta de Andalucía A‐0023‐2015 A‐0003‐2016 CTS‐1406 BIO‐0139Andalusian Ministry of Health C‐0015‐2014CIBERobn PI13/ 02043 PI16/0017

Language report for Catalan (English version)

The central objective of the Metanet4u project is to contribute to the establishment of a pan-European digital platform that makes available language resources and services, encompassing both datasets and software tools, for speech and language processing, and supports a new generation of exchange facilities for them.Peer ReviewedPreprin