A novel coplanar slot antenna structure for wireless applications

This paper presents a new compact broadband coplanar slot antenna for multiple wireless communication applications which include WIMAX, RFID, WLAN and ISM bands. The antenna structure is based on the CPW-fed combined with a slot technique and a modified geometry antenna in order to enlarge the bandwidth. The antenna parameters have been investigated and optimized by using Momentum software integrated into ADS” Advanced Design System” from Agilent Technologies with a comparison of the results using another simulator CST Microwave Studio. The measured input impedance bandwidth, ranging from 2.15GHz to 4.4GHz, is obtained with a return loss less than - 10dB, corresponding to 66.7% at 3.27GHz as a center frequency. The design considerations for achieving broadband antenna and both experimental, simulated results are presented

Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy

YesTumour suppressor proteins, such as p53, BRCA1, and ABC, play key roles in preventing the development of a malignant phenotype, but those that function as transcriptional regulators need to enter the nucleus in order to function. The export of proteins between the nucleus and cytoplasm is complex. It occurs through nuclear pores and exported proteins need a nuclear export signal (NES) to bind to nuclear exportin proteins, including CRM1 (Chromosomal Region Maintenance protein 1), and the energy for this process is provided by the RanGTP/RanGDP gradient. Due to the loss of DNA repair and cell cycle checkpoints, drug resistance is a major problem in cancer treatment, and often an initially successful treatment will fail due to the development of resistance. An important mechanism underlying resistance is nuclear export, and a number of strategies that can prevent nuclear export may reverse resistance. Examples include inhibitors of CRM1, antibodies to the nuclear export signal, and alteration of nuclear pore structure. Each of these are considered in this review

Quantum teleportation and dynamics of quantum coherence and metrological non-classical correlations for open two-qubit systems: A study of Markovian and non-Markovian regimes

We investigate the dynamics of non-classical correlations and quantum coherence in open quantum systems by employing metrics like local quantum Fisher information, local quantum uncertainty, and quantum Jensen-Shannon divergence. Our focus here is on a system of two qubits in two distinct physical situations: the first one when the two qubits are coupled to a single-mode cavity, while the second consists of two qubits immersed in dephasing reservoirs. Our study places significant emphasis on how the evolution of these quantum criterion is influenced by the initial state's purity (whether pure or mixed) and the nature of the environment (whether Markovian or non-Markovian). We observe that a decrease in the initial state's purity corresponds to a reduction in both quantum correlations and quantum coherence, whereas higher purity enhances these quantumness. Furthermore, we establish a quantum teleportation strategy based on the two different physical scenarios. In this approach, the resulting state of the two qubits functions as a quantum channel integrated into a quantum teleportation protocol. We also analyze how the purity of the initial state and the Markovian or non-Markovian regimes impact the quantum teleportation process

A new compact printed antenna structure for multiple wideband applications

This paper presents the design of a new compact antenna structure for multiple incorporating operation service. The proposed antenna is suitable to operate at three different frequency bands, (1.77GHz-2.67GHz), (3.1GHz- 4.58GHz), and (5.5GHz-6.5GHz) with a return loss less than -10dB. The antenna structure includes a CPW fed line, the technique used to enlarge the frequency bands is the slots technique and in the same time we have developed a new antenna structure which operates in various wireless communication applications. The antenna parameters have been investigated and optimized by using CST Microwave Studio. To validate the CST Microwave Studio results before the antenna achievement, we have conducted another study by using ADS. The final circuit was achieved, measured and validated. Experimental results show that the proposed antenna with compact size of 42*32.7 mm2 has good radiation characteristics and operating in specific microwave applications ISM band, WLAN, WIFI, WIMAX and RFID

A new compact and miniaturized GCPW-fed slotted rectangular antenna for wideband UHF FIRD applications

This paper presents the development of a new miniaturized and compact GCPW-fed slotted rectangular antenna structure reader for wideband UHF RFID applications. The optimized proposed antenna is suitable to operate a large frequency-band range from 0.8GHz to 1.3GHz with a bandwidth of 500MHz with a return loss less than -10dB. The antenna is based on a 1.6mm thickness FR4 epoxy substrate with a reduce dimensions compared to the simple rectangular antenna and size of proposed antenna is 47*40mm2. The new design consists of a compact rectangular patch with symmetric U-shaped slots and I-shaped include a partial ground plan and fed by 50 Grounded coplanar line. The antenna parameters have been investigated and optimized by using CST Microwave Studio. To validate the CST Microwave Studio results before the antenna achievement, we have conducted another study by using ADS. The final circuit achieved, measured and validated. Experimental results show that the proposed antenna has good radiation characteristics and operating in UHF-RFID applications

New compact antenna structures with a slot shaped and a stub tuning for ultra wide band applications

This paper presents the design of new compact printed broadband antennas for Ultra Wide Band applications. The antenna structures are based on the CPW-fed combined with a slot and a stub line to increase the bandwidth. The proposed antennas have been successfully designed, optimized and simulated by using Momentum software integrated into ADS "Advanced Design System" and CST Microwave Studio. The measured input impedance bandwidth of the final broadband antennas ranging from 2.1-7.3 GHz and 2.1-11 GHz. The design considerations for achieving broadband antennas and both simulated, experimental results are presented and discussed

Design of a New Compact Printed MonopoleAntenna by using Tuning Stub for UWB Applications

Wideband applications put a new demand on antennas pertaining to size, gain, efficiency, bandwidth and more. This paper presents the design and analysis of a new compact broadband coplanar slot antenna for multiple wireless communication applications. The antenna structure is based on the CPW-fed combined with slot technique, stub tuning and a modified geometry antenna in order to enlarge the bandwidth. The antenna parameters have been investigated and optimized by using CST Microwave Studio with a comparison of the results by using another simulator ADS” Advanced Design System from Agilent Technologies. The simulated input impedance bandwidth, ranging from 8GHz to 23GHz, is obtained with a return loss less than -10dB, corresponding to 96.77% at 15.5GHz as a center frequency. Details of the proposed antenna design and simulated results are described and discussed

Nano-encapsulation of a novel anti-Ran-GTPase peptide for blockade of regulator of chromosome condensation (RCC1) function in MDA-MB-231 breast cancer cells

Ran is a small ras-related GTPase and is highly expressed in aggressive breast carcinoma. Overexpression induces malignant transformation and drives metastatic growth. We have designed a novel series of anti-Ran-GTPase peptides, which prevents Ran hydrolysis and activation, and although they display effectiveness in silico, peptide activity is suboptimal in vitro due to reduced bioavailability and poor delivery. To overcome this drawback, we delivered an anti-Ran-GTPase peptide using encapsulation in PLGA-based nanoparticles (NP). Formulation variables within a double emulsion solvent evaporation technique were controlled to optimise physicochemical properties. NP were spherical and negatively charged with a mean diameter of 182–277 nm. Peptide integrity and stability were maintained after encapsulation and release kinetics followed a sustained profile. We were interested in the relationship between cellular uptake and poly(ethylene glycol) (PEG) in the NP matrix, with results showing enhanced in vitro uptake with increasing PEG content. Peptide-loaded, pegylated (10% PEG)-PLGA NP induced significant cytotoxic and apoptotic effects in MDA-MB-231 breast cancer cells, with no evidence of similar effects in cells pulsed with free peptide. Western blot analysis showed that encapsulated peptide interfered with the proposed signal transduction pathway of the Ran gene. Our novel blockade peptide prevented Ran activation by blockage of regulator of chromosome condensation 1 (RCC1) following peptide release directly in the cytoplasm once endocytosis of the peptide-loaded nanoparticle has occurred. RCC1 blockage was effective only when a nanoparticulate delivery approach was adopted

Chemical composition, antibacterial and antioxidant properties of three Moroccan citrus peel essential oils

Citrus peels, which make up a significant portion of the entire fruit and are frequently rejected by nature and have a detrimental influence on the environment, are the focus of this study. These barks can be a highly valuable source of plant material. Three different citrus species C. limonum, C. reticulata, and C. Paradisi had their essential oils extracted from their peels(by-products) to create these citrus co-products (essential oil).The findings demonstrate how rich these citrus species are in essential oils. Limonene is the predominant component for the three, accounting for percentages of 56.3%, 76.5%, and 71.7% for C. paradisi, C. reticulata, and C. limonum, respectively, in their chemical composition as determined by GC/MS analysis. Their antioxidant activity was assessed using DPPH and validated using the FRAP assay. Furthermore, essential oils antimicrobial efficacy against five pathogenic strains: Escherichia coli, Enterococcus feacalis, Staphylococcus aureus, Candida albicans, and Sacharomyces cerevisiae, demonstrates significant antibacterial potential, particularly against Candida albicans

6-Methyl-1-(nitromethyl)-4-(propan-2-yl)naphthalene

The title compound, C15H17NO2, was synthesized in two steps from a mixture of α-himachalene (2-methylene-6,6,9-trimethylbicyclo[5.4.01,7]undec-8-ene), β-himachalene (2,6,6,9-tetramethylbicyclo[5.4.01,7]undeca-1,8-diene) and γ-himachalene (2,6,6,9-tetramethylbicyclo[5.4.01,7]undeca-2,8-diene), which was isolated from an essential oil of the Atlas cedar (Cedrus atlantica). The nitro group and the isopropyl group lie almost normal to the mean plane of the naphthalene moiety, making dihedral angles of 83.13 (19) and 71.72 (16)°, respectively, and are inclined to one another by 49.8 (2)°. In the crystal, molecules are linked by pairs of C—H...π interactions and weak C—H...O interactions