1,852 research outputs found

    Sobre la nomenclatura de una especie del género Asteriscus Mill. (Asteraceae)

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    On the nomenclature of a species of the genus Asteriscus Mill. (Asteraceae) Palabras clave. Asteriscus, nomenclatura, Península Ibérica, N África.Key words. Asteriscus, nomenclature, Iberian Peninsula, N Afrique

    Geminiviral protein Rep interferes in PCNA sumoylation

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    Rep is a multifunctional protein essential for replication of geminivirus that interferes with the sumoylation of a key protein in the DNA replication, PCNA (Proliferating Cell Nuclear Antigen). It is known that Rep is capable of interacting with a plethora of plant proteins, including PCNA. Despite the biological significance remains unknown, it’s thought that this interaction should play a key role for generating new copies of the virus genome. Therefore, in order to characterize this interaction, we study which lysines are sumoylated in tomato PCNA (SlPCNA). Considering conservation, location and presence of sumoylation domain criteria, we have identified some candidate lysines and studied how its mutation affects this protein sumoylation in Escherichia coli assays. Finally, we plan to confirm and characterize the Rep interference on SlPCNA sumoylation and determine if this interference occurs in planta.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    An analysis of the competitiveness of the furniture industry in the Valencian Community

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    In the international economic context, some changes affecting directly the behaviour of industries are taking place. These world level changes are due, in part, to the so called globalization process, that has modified the production activity, growing up the rivalry between firms. If we want to respond with success to the new situation a clear consecuence must generate, and that is the need to maintain a higher level of competitiveness in an industrial area. It is proven that there are competitive industries with a high employment level, a high productivity rate, and an important amount of exports. These industries are the basis of the regional economy, even tha national and, therefore, it is necesary to know the industry structure, and the reasons why a competitive advantage can be stablished. In our opinion, this is the way to get a wide vision of the dynamics of the system. In other words, we need to know which aspects, endogenous or exogenous, can give a competitive advantage to the industry. Spain in general, and in the Valencian Comunity, in particular, has an export-trade orientated structure: The tile industry, the shoe industry or the furniture one, are good examples of competitive industries, which are considered strategic parts of the valencian economic dynamics, even though they are also considered “traditional industries”. We have choosen the furniture industry to analize its competitiveness. The hypothesis that we want to contrast is that “in the Valencian Comunity, or more precisely, in the area of Valencia, an hightly competitive industrial cluster has been formed (defined as critical masses of unususal competitive success in particular fields by Porter, 1998). The relationships between its memebers, the competition and cooperation established among them, and the innovation generated inside it, implicate a dynamic behavior of the firms of the cluster and the competitiveness of the whole industry. In this study, we demonstrate the validity of the “cluster model” to explain competitiveness of the Valencian furniture industry, and how the factors that are implied are local.

    The Importance of Creative Industry Agglomerations in Explaining the Wealth of European Regions

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    This paper examines the existence of regional agglomerations of manufacturing, service and creative industries, the relationship between these industries and the wealth of regions and their industrial structure. Through an analysis of 250 European regions, three important conclusions can be inferred from the results obtained in this paper. The first is that creative industries play an important role in the wealth of a region. The second is that the most creative regions are characterized by having more high-tech manufacturing industries than the rest of the regions although the number of low-tech manufacturing firms is similar. Lastly, the industrial structure of each region has a greater influence on regional wealth than the existence of industrial agglomerations. The importance of this paper resides in the fact that up until now no analysis has demonstrated that creative industries are the most important industries in regional wealth.

    Hybridizing concentrated solar power (CSP) with biogas and biomethane as an alternative to natural gas: Analysis of environmental performance using LCA

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    Concentrating Solar Power (CSP) plants typically incorporate one or various auxiliary boilers operating in parallel to the solar field to facilitate start up operations, provide system stability, avoid freezing of heat transfer fluid (HTF) and increase generation capacity. The environmental performance of these plants is highly influenced by the energy input and the type of auxiliary fuel, which in most cases is natural gas (NG). Replacing the NG with biogas or biomethane (BM) in commercial CSP installations is being considered as a means to produce electricity that is fully renewable and free from fossil inputs. Despite their renewable nature, the use of these biofuels also generates environmental impacts that need to be adequately identified and quantified. This paper investigates the environmental performance of a commercial wet-cooled parabolic trough 50 MWe CSP plant in Spain operating according to two strategies: solar-only, with minimum technically viable energy non-solar contribution; and hybrid operation, where 12 % of the electricity derives from auxiliary fuels (as permitted by Spanish legislation). The analysis was based on standard Life Cycle Assessment (LCA) methodology (ISO 14040-14040). The technical viability and the environmental profile of operating the CSP plant with different auxiliary fuels was evaluated, including: NG; biogas from an adjacent plant; and BM withdrawn from the gas network. The effect of using different substrates (biowaste, sewage sludge, grass and a mix of biowaste with animal manure) for the production of the biofuels was also investigated. The results showed that NG is responsible for most of the environmental damage associated with the operation of the plant in hybrid mode. Replacing NG with biogas resulted in a significant improvement of the environmental performance of the installation, primarily due to reduced impact in the following categories: natural land transformation, depletion of fossil resources, and climate change. However, despite the renewable nature of the biofuels, other environmental categories like human toxicity, eutrophication, acidification and marine ecotoxicity scored higher when using biogas and BM

    Transcriptional regulation os phenylalaline biosynthesis and utilization

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    Conifer trees divert large quantities of carbon into the biosynthesis of phenylpropanoids, particularly to generate lignin, an important constituent of wood. Since phenylalanine is the precursor for phenylpropanoid biosynthesis, the precise regulation of phenylalanine synthesis and utilization should occur simultaneously. This crucial pathway is finely regulated primarily at the transcriptional level. Transcriptome analyses indicate that the transcription factors (TFs) preferentially expressed during wood formation in plants belong to the MYB and NAC families. Craven-Bartle et al. (2013) have shown in conifers that Myb8 is a candidate regulator of key genes in phenylalanine biosynthesis involved in the supply of the phenylpropane carbon skeleton necessary for lignin biosynthesis. This TF is able to bind AC elements present in the promoter regions of these genes to activate transcription. Constitutive overexpression of Myb8 in white spruce increased secondary-wall thickening and led to ectopic lignin deposition (Bomal et al. 2008). In Arabidopsis, the transcriptional network controlling secondary cell wall involves NAC-domain regulators operating upstream Myb transcription factors. Functional orthologues of members of this network described have been identified in poplar and eucalyptus, but in conifers functional evidence had only been obtained for MYBs. We have identified in the P. pinaster genome 37 genes encoding NAC proteins, which 3 NAC proteins could be potential candidates to be involved in vascular development (Pascual et al. 2015). The understanding of the transcriptional regulatory network associated to phenylpropanoids and lignin biosynthesis in conifers is crucial for future applications in tree improvement and sustainable forest management. This work is supported by the projects BIO2012-33797, BIO2015-69285-R and BIO-474 References: Bomal C, et al. (2008) Involvement of Pinus taeda MYB1 and MYB8 in phenylpropanoid metabolism and secondary cell wall biogenesis: a comparative in planta analysis. J Exp Bot. 59: 3925-3939. Craven-Bartle B, et al. (2013) A Myb transcription factor regulates genes of the phenylalanine pathway in maritime pine. Plant J, 74: 755-766. Pascual MB, et al. (2015) The NAC transcription factor family in maritime pine (Pinus pinaster): molecular regulation of two genes involved in stress responses. BMC Plant Biol, 15: 254.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Analysing innovation in museums through qualitative comparative analysis

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    This is an Accepted Manuscript of an article published by Taylor & Francis in Knowledge Management Research & Practice, on 22/04/2019, available online: https://www.tandfonline.com/doi/abs/10.1080/14778238.2019.1601505[EN] The aim of this paper is to analyse innovation in the processes undertaken by museums in the conservation and restoration of artworks. Information from 90 conservation and restoration departments from museums in 43 countries was analysed using qualitative comparative analysis. Two theoretical concepts - knowledge bases (analytical, synthetic, symbolic) and modes of innovations (Science, Technology and Innovation; Doing, Using, and Interacting) - were used to define necessary and sufficient conditions which explain innovation in artwork restoration. Two important results were obtained from the analysis. The first indicated that innovation was explained by the combination of symbolic and analytical knowledge bases (unrelated variety), and high innovation performance was also explained by the related variety in the analytical knowledge base. The second result revealed that innovation is higher when museums cooperate simultaneously with partners using the two modes of innovation.This work was supported by the Universitat Politecnica de Valencia [Research Project n. 2677-UPV, and SP20120346].De-Miguel-Molina, B.; Boix Domenech, R.; De-Miguel-Molina, M. (2019). Analysing innovation in museums through qualitative comparative analysis. Knowledge Management Research & Practice. 17(2):213-226. https://doi.org/10.1080/14778238.2019.1601505213226172Apanasovich, N. (2014). Modes of Innovation: A Grounded Meta-Analysis. Journal of the Knowledge Economy, 7(3), 720-737. doi:10.1007/s13132-014-0237-0Apanasovich, N., Alcalde Heras, H., & Parrilli, M. D. (2016). 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Research Policy, 34(8), 1173-1190. doi:10.1016/j.respol.2005.03.013Aslesen, H. W., & Pettersen, I. B. (2017). Entrepreneurial firms in STI and DUI mode clusters: do they need differentiated cluster facilitation? European Planning Studies, 25(6), 904-922. doi:10.1080/09654313.2017.1300238Boschma, R. (2018). A Concise History of the Knowledge Base Literature: Challenging Questions for Future Research. New Avenues for Regional Innovation Systems - Theoretical Advances, Empirical Cases and Policy Lessons, 23-40. doi:10.1007/978-3-319-71661-9_2Castro‐Martínez, E., Recasens, A., & Jiménez‐Sáez, F. (2013). Innovation systems in motion: an early music case. Management Decision, 51(6), 1276-1292. doi:10.1108/md-11-2011-0433Fitjar, R. D., & Rodríguez-Pose, A. (2013). Firm collaboration and modes of innovation in Norway. Research Policy, 42(1), 128-138. doi:10.1016/j.respol.2012.05.009González-Pernía, J. L., Parrilli, M. D., & Peña-Legazkue, I. (2014). STI–DUI learning modes, firm–university collaboration and innovation. The Journal of Technology Transfer, 40(3), 475-492. doi:10.1007/s10961-014-9352-0Grillitsch, M., Martin, R., & Srholec, M. (2016). Knowledge Base Combinations and Innovation Performance in Swedish Regions. Economic Geography, 93(5), 458-479. doi:10.1080/00130095.2016.1154442Grillitsch, M., & Trippl, M. (2013). Combining Knowledge from Different Sources, Channels and Geographical Scales. European Planning Studies, 22(11), 2305-2325. doi:10.1080/09654313.2013.835793Hauge, E. S., Kyllingstad, N., Maehle, N., & Schulze-Krogh, A. C. (2017). Developing cross-industry innovation capability: regional drivers and indicators within firms. European Planning Studies, 25(3), 388-405. doi:10.1080/09654313.2016.1276158Herstad, S. J., Aslesen, H. W., & Ebersberger, B. (2014). On industrial knowledge bases, commercial opportunities and global innovation network linkages. Research Policy, 43(3), 495-504. doi:10.1016/j.respol.2013.08.003Hervas-Oliver, J.-L., Sempere-Ripoll, F., Boronat-Moll, C., & Rojas, R. (2014). Technological innovation without R&D: unfolding the extra gains of management innovations on technological performance. Technology Analysis & Strategic Management, 27(1), 19-38. doi:10.1080/09537325.2014.944147Hervas-Oliver, J.-L., Sempere-Ripoll, F., Boronat-Moll, C., & Rojas-Alvarado, R. (2017). On the joint effect of technological and management innovations on performance: increasing or diminishing returns? Technology Analysis & Strategic Management, 30(5), 569-581. doi:10.1080/09537325.2017.1343462Ingstrup, M. B., Jensen, S., & Christensen, P. R. (2017). Cluster evolution and the change of knowledge bases: the development of a design cluster. European Planning Studies, 25(2), 202-220. doi:10.1080/09654313.2016.1276885Isaksen, A., & Nilsson, M. (2013). Combined Innovation Policy: Linking Scientific and Practical Knowledge in Innovation Systems. European Planning Studies, 21(12), 1919-1936. doi:10.1080/09654313.2012.722966Isaksen, A., & Trippl, M. (2017). Innovation in space: the mosaic of regional innovation patterns. Oxford Review of Economic Policy, 33(1), 122-140. doi:10.1093/oxrep/grw035Jensen, M. B., Johnson, B., Lorenz, E., & Lundvall, B. Å. (2007). Forms of knowledge and modes of innovation. Research Policy, 36(5), 680-693. doi:10.1016/j.respol.2007.01.006Klein, R. R. (2011). Where music and knowledge meet: a comparison of temporary events in Los Angeles and Columbus, Ohio. Area, 43(3), 320-326. doi:10.1111/j.1475-4762.2011.00997.xKvětoň, V., & Kadlec, V. (2018). Evolution of knowledge bases in European regions: searching for spatial regularities and links with innovation performance. European Planning Studies, 26(7), 1366-1388. doi:10.1080/09654313.2018.1464128Laestadius, S. (2002). Biotechnology and the Potential for a Radical Shift of Technology in Forest Industry. Economics of Science, Technology and Innovation, 333-362. doi:10.1007/978-1-4615-0915-8_11Longo, M., Mariani, M. M., & Mura, M. (2009). The effect of intellectual capital attributes on organizational performance. The case of the Bologna Opera House. Knowledge Management Research & Practice, 7(4), 365-376. doi:10.1057/kmrp.2009.28Manniche, J. (2012). Combinatorial Knowledge Dynamics: On the Usefulness of the Differentiated Knowledge Bases Model. European Planning Studies, 20(11), 1823-1841. doi:10.1080/09654313.2012.723423Manniche, J., Moodysson, J., & Testa, S. (2016). Combinatorial Knowledge Bases: An Integrative and Dynamic Approach to Innovation Studies. Economic Geography, 93(5), 480-499. doi:10.1080/00130095.2016.1205948Martin, R. (2012). Measuring Knowledge Bases in Swedish Regions. European Planning Studies, 20(9), 1569-1582. doi:10.1080/09654313.2012.708022Martin, R., & Moodysson, J. (2011). Comparing knowledge bases: on the geography and organization of knowledge sourcing in the regional innovation system of Scania, Sweden. European Urban and Regional Studies, 20(2), 170-187. doi:10.1177/0969776411427326McIver, D., Fitzsimmons, S., & Lengnick-Hall, C. (2018). Integrating knowledge in organizations: examining performance and integration difficulties. Knowledge Management Research & Practice, 17(1), 14-23. doi:10.1080/14778238.2018.1538667Mohammadi, A., Broström, A., & Franzoni, C. (2017). Workforce Composition and Innovation: How Diversity in Employees’ Ethnic and Educational Backgrounds Facilitates Firm-Level Innovativeness. Journal of Product Innovation Management, 34(4), 406-426. doi:10.1111/jpim.12388Mol, M. J., & Birkinshaw, J. (2014). The Role of External Involvement in the Creation of Management Innovations. Organization Studies, 35(9), 1287-1312. doi:10.1177/0170840614539313Moodysson, J., Coenen, L., & Asheim, B. (2008). 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    FORTALECIMIENTO DEL ACOMPAÑAMIENTO, SEGUIMIENTO Y CONTROL DE LOS ESTUDIANTES EN SUS PROCESOS ACADÉMICOS UNIDAD DOCENTE BÀSICA (UDB) – MATEMÁTICA – DEPARTAMENTO DE CIENCIAS BÁSICAS DE LA FACULTAD REGIONAL BUENOS AIRES DE LA UNIVERSIDAD TECNOLÓGICA NACIONAL

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    Los alumnos que ingresan a la Universidad acceden a la misma careciendo de las capacidades necesarias para poder insertarse, sin mayores dificultades, en el nivel superior de enseñanza. Este objetivo de este trabajo de investigación - acción está centrado en la implementación de la tutoría como estrategia de intervención en el proceso de aprendizaje de los alumnos, ya que constituye una acción educativa que permite el seguimiento tanto individual como grupal en el proceso de formación integral de los alumnos, así como el desarrollo de estrategias dirigidas a estimular la conciencia de habilidades y destrezas de los estudiantes con la finalidad, entre otras, de adquirir eficiencia en su nivel académico y aumentar la retención. El proceso de investigación está aportando conocimiento nuevo a los ya existentes en el área de acción tutorial –presencial- en la universidad, en tanto que los resultados obtenidos permitirán efectuar pronósticos sobre el comportamiento y la actitud del estudiante ingresante a la universidad frente al impacto de un régimen y habito de estudio nuevo para él. Las conclusiones obtenidas podrán ser consideradas antecedentes valiosos para la confección y/o ajustes de nuevos diseños curriculares, centrados en los tiempos de aprendizaje del alumno y su estado formativo inicial con el que enfrenta los nuevos procesos de aprendizaje – enseñanza en la universidad

    Recognition, interpretation and teaching of sign lan-guage in the official languages of Ecuador

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    Abstract. The lack of an application that can be used within the teaching sign language learning process allowed us to propose this research, creating two technological applications based on the modalities and materials used during the Sign Language teaching process in Ecuador, using its own methodology divided into four phases, it was obtained that the desktop application recognizes and interprets in real time the gestures made with a range of effectiveness of 90% to 100% Working on clear funds, while the APP allows you to learn the basic signs and words used by people with hearing impairment, both applications work in Spanish and Kichwa
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