The Interrelation of the Mother’s Health Status with the State of Health of First- and Second-Year-Old Children

We evaluated the state of health of the mother and child at birth, and the probability of the diagnosis of cancelation in the child at the end of the second year of life. The sample consisted of 100 mother-child dyads. The complex assessment of the children’s health status was based on the individual medical records. Mothers filled the questionnaire evaluating the mother’s relation to her child during the first 2 years of life, and the questionnaire aimed at assessing the emotional intelligence level. Almost all the children at birth have one or the other diagnosis. There is a positive connection between the number of the diagnoses in the first- and second-year-old children during their stay in the maternity ward and perinatal pathology factors of the mother. But by the end of the second year of life in 60% of the children, these diagnoses were canceled. The healthier the mother, the more positive the prognosis with regard to the child’s health within the first 2 years of living is. Positive prognosis with regard to the first-year-old children’s health depends upon the acceptance of the child by the mother: the higher the value on the scale of acceptance-nonacceptance is, the better the child’s health is

Forecasting of principal directions of Ukrainian insurance market development based on German insurance market indices

The basic aspects of German and Ukrainian insurance markets development are addressed in this paper. Also, their interrelationships are considered based on the forecasting of most relevant descriptions of insurance activity given the time lag. To this end, correlative-regressive analysis is employed. This approach makes it possible to predict the basic aspects of domestic insurance markets activity directions

THE INTERCONNECTION OF INHIBITORY CONTROL AND THE INTERNAL PICTURE OF HEALTH IN PRIMARY SCHOOLCHILDREN

Supusimos que la actitud consciente de la salud de una persona, cuando se actualiza en una acción específica, debe estar conectada a ciertas características psicofisiológicas objetivas, por ejemplo, al control inhibitorio. El objetivo de la presente investigación fue estudiar la interrelación del control inhibitorio y el cuadro de salud interna (también denominado IPH) en los escolares de primaria. Examinamos 72 escolares de primaria (edad media (DE): 10,3 (0,9) años). El control inhibitorio fue evaluado por la herramienta ReBOS (Vergunov, Nikolaeva, 2018). El nivel de IPH se midió mediante un cuestionario (Nikolaeva et al., 2014). Se descubrió que cuanto mayor es el nivel de IPH que tienen los niños, mejor controlan sus acciones. La forma en que las niñas responden a participar en una actividad está directamente relacionada con su desarrollo de IPH. Pero a diferencia de los datos obtenidos en el grupo de niños, el control inhibitorio de las niñas no está relacionado con su nivel de IPH.Supomos que a atitude consciente da saúde de uma pessoa, quando realizada em uma ação específica, deva estar conectada a certas características psicofisiológicas objetivas, por exemplo, ao controle inibitório. O objetivo da presente pesquisa foi estudar a inter-relação do controle inibitório e do quadro interno de saúde (mais conhecido como IPH) em escolares do ensino fundamental. Foram examinados 72 escolares do ensino fundamental (idade média (DP): 10,3 (0,9) anos). O controle inibitório foi avaliado pela ferramenta ReBOS (Vergunov, Nikolaeva, 2018). O nível de IPH foi medido por um questionário (Nikolaeva et al., 2014). Verificou-se que quanto mais alto o nível de IPH, maior o controle sobre suas ações. A maneira como as meninas respondem à participação em uma atividade está diretamente relacionada ao seu desenvolvimento de IPH. Porém, diferentemente dos dados obtidos no grupo dos meninos, o controle inibitório das meninas não está relacionado ao seu nível de IPH.    We supposed that a person’s health-conscious attitude, when actualized in a specific action must be connected to certain objective psychophysiological characteristics, for example, to inhibitory control. The aim of the present research was to study the interrelation of the inhibitory control and the internal health picture (further referred to as IPH) in primary schoolchildren. We examined 72 primary schoolchildren (mean (SD) age: 10.3 (0.9) years). Inhibitory control was assessed by the ReBOS tool (Vergunov, Nikolaeva, 2018). The IPH level was measured by a questionnaire (Nikolaeva et al., 2014). It was found that the higher IPH level boys have, the better they control their actions. The way girls respond to participating in an activity is directly related to their IPH development. But unlike the data obtained in the boys' group, the girls' inhibitory control is not related to their IPH level

EFFICIENCY AND SAFETY OF LEFLUNOMIDE TREATMENT IN PATIENTS WITH PULMONARY SARCOIDOSIS

Patients who have contraindications to the prescription of GCs (glucocorticosteroids), or have developed serious side effects during treatment with GCs, as well as patients with resistance to GCs therapy, are prescribed immunosuppressants. The aim of the research - to study the efficacy of leflunomide monotherapy in patients with pulmonary sarcoidosis with contraindications to prescription or serious side effects of glucocorticosteroids. Fourteen patients with sarcoidosis of the respiratory system of stage II were examined – 12 women and 2 men aged 30 to 69 years. In 10 patients there were contraindications to the appointment of GCs (diabetes mellitus – 5, hypertension – 3, obesity – 1, exacerbation of gastric ulcer – 1), which caused the appointment of immunosuppressive therapy as a starting. In 4 cases, serious side effects of SCs were noted, requiring the drug to be abolished (osteoporosis – 3, steroid diabetes – 1). Leflunomide was administered at a dose of 20 mg per day, daily for 3 months. The evaluation of efficacy was carried out using computed tomography of the thoracic cavity organs, body plethysmography, spirometry and determination of the diffusivity of the lungs. Monotherapy with leflunomide in patients with contraindications to prescription or serious side effects of GCs was successful in 7 out of 13 patients, in 2 patients there was a stabilization of the process, in 4 patients with leflunomide therapy progression of the disease was noted and in 1 case the treatment was discontinued due to serious side effects of preparation. The results obtained make it possible to recommend the use of leflunomide as monotherapy in patients with pulmonary sarcoidosis with contraindications to the prescription and/or poor tolerability of GCs and methotrexate. It is necessary to continue studying the possibilities of combined use of leflunomide with other drugs of the first line

Features of digital socialization of primary school students in the context of different levels of Internet involvement

Nowadays, human life is greatly influenced by digitalization and informatization, which requires the reinterpretation of the matter of social formation and human development in the context of ontogenesis. From the moment of birth, a child lives in a mixed social and digital environment, which influences traditional socialization in one way or another. The researchers identify both positive and negative aspects of digital socialization of the younger generation. The authors of the present research analyzed the features of digital socialization of primary school students with different levels of Internet involvement. The experiment on the identification of Internet addiction involved 540 parents. The sample on the study of digital socialization included 316 primary school students aged 7 to 9. On the one hand, the results showed the preservation and demonstration of the content and methods of traditional socialization among younger students of all levels of Internet involvement in terms of digital socialization. This fact indicates the integration and combination of digital and traditional socialization. On the other hand, the increase in the levels of Internet involvement contributes to the replacement and transition from traditional socialization to a digital one

The use of the Karno and Stackelberg models for the study of operational and marketing strategies in reinsurance companies’ behavior

The article studies the modeling and optimization of the main parameters in the functioning of reinsurance companies based on the analysis of operational and marketing strategies of their behavior on the reinsurance market. It offers to maximize the function of a reinsurance company’s profitability by determining the optimal quantity of reinsurances of a certain risk as a result of the Karno and Stackelberg models’ adaptation to the reinsurance market. This approach studies models with and without consideration of the competitors’ behavior on the market as well as their different combinations

Optimization of cattle by-products amino acid composition formula

ArticleThe aim of this research was to develop optimal formulations of by-product mixtures in terms of biological value using MS Excel Solver standard software application. The objects of study were underutilized cattle by-products as tripe, ears, lips, lungs, and heart. Physical and chemical studies were carried out to compile a database of the by-products used. As a result, the protein content was 14.3% in tripe, 24.6% in lips, 24.9% in ears, 15.2% in lungs, and 16.8% in heart (P < 0.05). The content of essential amino acids in various by-products, determined by highperformance liquid chromatography, did not have significant differences compared with the results obtained by other researchers. While conducting optimization of the by-product formulation, focused on the physiologically-based content of the essential amino acids in the ‛ideal’ protein according to the Food and Agriculture Organization of the United Nations and the World Health Organization (FAO/WHO). Essential amino acids index (EAAI) was chosen as the goal function. In the process of optimization, indicators such as chemical score, EAAI, biological value, and coefficient of amino acid score differences (CAASD) were calculated. Several variants of the formulations with high biological value were obtained as a result of the optimization. According to the results of the research it was found that more balanced ratio of the essential amino acids was in the following formulations: 1 – tripe (4.9%), ears (28.4%) and heart (66.7%) or 2 – ears (25.4%), lips (8.9%) and heart (65.7%). According to the results, the highest in vitro protein digestibility was in compositions number 1 and 2 (78.2% and 76.8%), which correlated with the calculated biological value. Thus, the use of computer modeling allowed obtaining the formulations of the by-products composition with the highest possible biological value by varying the content of the various by-products