Laparascopic Hernia Repair with the Use of TiNi-based alloy

The reduction of the endoscopic methods of the inguinal hernia surgical treatment to the everyday practice of the surgery departments led to the better results of treatment. However, the recurrence rate remain sat the level of 2.2-4.4%, and the rate of the intraoperative and postoperative complications is 8%. The paper describes treating 78 patients (59 pations underwent the reduction of the endoscopic methods of the inguinal hernia surgical treatment to the everyday practice of the surgery departments led to the better results of treatment and 19 patients underwent the laparoscopic transabdominal hernia repair with the usage of porous nickelid titanium. in the period from 2000 to 2016. It shows a procedure of installing porous nickelid titanium, gives the obtained results of the procedure and analizes the experience of world literature. The procedure of the laparoscopic hernia repair allows to lessen the injury rate of the surgery, to lessen the possibility of the postoperative complications and to simplify the medical staff work

Sigmatropic Rearrangement of Vinyl Aziridines: Expedient Synthesis of Cyclic Sulfoximines from Chiral Sulfinimines

A novel rearrangement of 2-vinyl aziridine 2-carboxylates to unusual chiral cyclic sulfoximines is described herein. The method allows the synthesis of substituted cyclic sulfoximines in high yields with complete stereocontrol, displaying a wide substrate scope under mild conditions. Further development of a one-pot process directly from sulfinimines shows the synthetic applicability of this protocol, providing access to complex chiral sulfoximines in only two steps from commercially available aldehydes. A mechanistic hypothesis and synthetic application in the formal synthesis of trachelanthamidine by transformation of a cyclic sulfoximine into a pyrroline is also disclosed