Diagnóstico 5S de la gestión del almacén de Nor Diesel S. R. L. – Trujillo, 2016

RESUMEN La presente investigación está enfocada en la realización de un diagnóstico 5S con el objetivo de sentar las bases para que, con la posterior aplicación del método, se pueda llegar a mejorar la gestión del almacén de la empresa Nor Diesel S.R.L. de la ciudad de Trujillo y, de esa manera mantener un nivel óptimo en todos los procesos realizados, en el control de las entradas y salidas del almacén y el control de la limpieza y orden; e ir incrementando, con el transcurso del tiempo, el compromiso de todos los colaboradores con un proceso de mejora continua del almacén y de la empresa en general, que se deriva de la implementación de las 5S. Mantener una adecuada gestión del almacén es vital y básico para toda organización; de ahí que sea tan importante mantener un buen nivel en el control del mismo pues es beneficioso tanto para los colaboradores vinculados al almacén como para la empresa. Por ello, es importante mantener un compromiso constante de cada una de las partes de la empresa con el proceso de la elaboración del diagnóstico 5S, para que éste pueda ser exitosamente planteado y, de esa manera la empresa pueda notar sus puntos débiles en la gestión del almacén y así poder aplicar con posterioridad las 5S satisfactoriamente, con pleno conocimiento de lo que les hace falta y lo que deben hacer para implementarlo. Para determinar la situación actual del almacén de la empresa Nor Diesel S.R.L. se efectuó un diagnóstico basado en la realización de encuestas dirigidas a los colaboradores relacionados con el almacén, para poder determinar con mayor exactitud las carencias o dificultades que aquejan al área. Con este diagnóstico 5S, se facilitará la posterior implementación del Programa de Mejora Continua 5S ya que éste estará correctamente adaptado a la situación diagnosticada de la empresa, se podrá lograr mejorar la gestión del almacén, suprimiendo los malos hábitos y generando conductas beneficiosas para con el mantenimiento de la mejora continua en el área y en la empresa.ABSTRACT This investigation is focused on the proposal of implementation of Continuous Improvement Program 5S in order to improve the management of Nor Diesel Company´s warehouse in the city of Trujillo and, in that way, keep an optimum level in all the processes, the control of inputs and outputs of the warehouse and the control of cleaning and order; and increase, with the pass of the time, the commitment of all of the workers with a continuous improvement process of the warehouse and the company, derived from the implementation of 5S. Keep an appropriate warehouse´s management is vital and basic for all the organizations; that is why is so important keep a good level of control of it because it´s beneficial to warehouse´s workers and to the company. That is why is so important keep a constant commitment from all the parts of the company with the process of making the diagnosis 5S, so that it can be successfully raised and thus the company can note their weaknesses in warehouse´s management and to apply 5S successfully after that, with full knowledge of what they need and what they must do to implement it. To determine the current status of Nor Diesel Company´s warehouse, was made a diagnostic based on the surveys aimed to warehouse workers, to determine more exactly the shortcomings or difficulties that attaint the area. With this diagnosis 5S, the subsequent implementation of Continuous Improvement Program 5S will be provided as it is properly adapted to the diagnosed situation of the company can be achieved to improve warehouse´s management, eliminating bad habits and creating beneficial behaviors with maintaining continuous improvement in the area and the company

VIOLÊNCIA DE GÊNERO NO ESPAÇO UNIVERSITÁRIO

Objetivo: reconocer lo que se entiende acerca de la violencia de género en el espacio universitario. Método: investigación exploratoria de enfoque cualitativo. Se realizaron entrevistas semiestructuradas con 38 participantes que experimentaban el contexto universitario, en el período de julio a septiembre de 2016. Los datos se analizaronpor medio del Análisis de Contenido con la asistencia del software webQDA. Resultados: se hicieron evidentes tres categorías empíricas: violencia de género; reconocimiento de la violencia de género en los espacios universitarios; y subjetividades de la violencia de género. Se destaca que la comunidad universitaria tiene dificultades para exponer lo que entiende acerca de la violencia de género. Conclusión: la violencia de género es la reproducción del poder sobre el otro, considerado “inferior”, concepto revelado en el ámbito estudiado. Es necesario dar visibilidad al fenómeno, por medio de habilidades para escuchar que no se traduzcan en la culpabilización de la persona expuesta a la violencia.Objetivo: reconhecer o entendimento acerca da violência de gênero no espaço universitário.Método: pesquisa exploratória de abordagem qualitativa. Foram realizadas entrevistas semiestruturadas com 38 participantes que vivenciavam o contexto universitário, no período de julho a setembro de 2016. Os dados foram analisados por meio da Análise de Conteúdo com apoio do software webQDA.Resultados: foram evidenciadas três categorias empíricas: violência de gênero; reconhecimento da violência de gênero nos espaços universitários; e subjetividades da violência de gênero. Destaca-se que a comunidade universitária tem dificuldades em expor sua compreensão acerca da violência de gênero.Conclusão: violência de gênero é a reprodução de poder sobre o outro, considerado “inferior”, concepção revelada no cenário estudado. É necessário dar visibilidade ao fenômeno, por meio de escuta que não se traduza na culpabilização do indivíduo exposto à violência.Objective: to reveal the understanding about gender-based violence in the university scenario. Method: a qualitative and exploratory research study. Semi-structured interviews were conducted with 38 participants who experienced the university context, from July to September 2016. The data were analyzed by means of Content Analysis, with the aid of the webQDA software.Results: three empirical categories were evidenced: gender-based violence; recognition of genderbased violence in university spaces; and subjectivities of gender-based violence. It is noteworthy that the university community has difficulties in exposing its understanding of gender-based violence.Conclusion: gender-based violence is the reproduction of power over the other, considered “inferior”, a concept revealed in the scenario under study. It is necessary to evidence the phenomenon through listening that does not translate into the blaming of the individual exposed to violence

Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute

In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a strategy that capitalises on previously acquired information and expertise, has emerged as a powerful approach to accelerate drug discovery and development processes, often at a fraction of the costs of de novo developments. For 80 years, collaborating within a network of partnerships, the Swiss Tropical and Public Health Institute (Swiss TPH) has been working along a value chain from innovation to validation and application to combat poverty-related diseases. This article presents an overview of selected know-how repurposing initiatives conducted at Swiss TPH with a particular emphasis on the exploration of drug development pathways in the context of neglected tropical diseases and other infectious diseases of poverty, such as schistosomiasis, malaria and human African trypanosomiasis

Salmonellosis in Calves by Serovar Dublin in Paraná State, Brazil - Clinicopathological Aspects

Background: Calf diarrhea remains one of the main diseases affecting the cattle industry. Persistence of this significant problem is associated with the complexity of factors that may be involved (infectious, environmental). An accurate diagnosis is essential for confirming the cause and helping clinicians and cattle producers to apply appropriate strategies in a timely manner. This report describes the histological changes according to the degree of salmonellosis severity, which is a contagious infectious disease caused by Salmonella enterica subsp. enterica, a Gram-negative bacterium, in two beef calves in northern Paraná State, southern Brazil. Cases: Two 90-day-old crossbred Angus and Nellore calves from a beef farm in northern Paraná State were referred to a Veterinary Hospital. Animal 1- developed acute clinical signs (enteritis, ataxia, and muscle rigidity) and died the day after the signs began. Gross findings included heavy and non-collapsed lungs, pulmonary oedema, hepatomegaly, enteritis, and severe diffuse typhlitis. Microscopic analysis revealed severe diffuse necrotic enteritis, typhlitis, severe diffuse interstitial pneumonia, moderate centrilobular hepatic necrosis, mild multifocal nephritis, and severe spleen and lymph node necrosis. Paratyphoid nodules were evidenced on the liver, spleen, and mesenteric lymph nodes. Animal 2- presented apathy, green fibrinous diarrhea, and died three days after the onset of clinical signs. The macroscopic examination showed moderate diffuse enteritis and hepatosplenomegaly. At the microscopic examination, many paratyphoid nodules were observed on the liver, spleen, kidneys, and Peyer's patches, which were associated with intralesional and intravascular bacilli. Additional findings included severe diffuse fibrinous necrotic enteritis with intralesional bacilli, diffuse interstitial pneumonia, multifocal splenic necrosis, lymphoid depletion, and moderate multifocal to coalescent lymphocytic nephritis. Histological Gram staining was performed on selected samples, revealing intralesional Gram-negative bacilli in the liver and intestine. Thus, liver and intestine fragments were used for the microbiological examination. Microbiological culture, isolation and biochemical tests identified the genus Salmonella spp. Then, the colonies were subjected to serological tests for serovar identification, according to ISO/TR 6579-3, which determined the serovar Dublin. After identifying the disease etiological agent, the outbreak was controlled by appropriate antibiotic therapy combined with the correction of sanitary measures.Discussion: Enteritis is a frequent disease in calves, posing a diagnostic challenge in identifying the etiological agent. In the present case, the histological, microbiological, and serological results confirmed a disseminated Salmonella spp. infection. The microscopic findings, such as interstitial pneumonia, fibrinous necrotic enteritis markedly in ileum and paratyphoid nodules in various organs, are the most common aspects of the disease. However, fibrinous cholecystitis, which is considered pathognomonic for salmonellosis, was not observed in this study. Therefore, the absence of such a lesion should not exclude the disease in sick animals. A microscopic injury score was used to determine lesion severity by assigning values from 1 to 4, wherein: 1 = no apparent lesions, 2 = mild lesions, 3 = moderate lesions, and 4 = severe lesions. Both calves were scored as 4. Multiple predisposing factors for the condition were identified in this farm such as different age animals in the same paddock and no specific paddock for sick animals, given that the infectious agent remains in feces, saliva, and nasal discharge. The serovar Dublin induces several clinical signs such as septicemic, respiratory, and enteric manifestations, making a clinical diagnosis a challenge. Keywords: dysbiosis, calf diarrhea, infection, paratyphoid nodules, septicemia.Descritores: disbiose, diarreia neonatal, infecção, nódulos paratifoides, septicemia.Título:  Salmonelose em bezerros pelo sorovar Dublin no estado do Paraná, Brasil - aspectos clínico-patológicos