Genetic basis of adaptation in Arabidopsis thaliana: Local adaptation at the seed dormancy QTL DOG1

Local adaptation provides an opportunity to study the genetic basis of adaptation and investigate the allelic architecture of adaptive genes. We study DELAY OF GERMINATION 1 (DOG1), a gene controlling natural variation in seed dormancy in Arabidopsis thaliana and investigate evolution of dormancy in 41 populations distributed in four regions separated by natural barriers. Using F ST and Q ST comparisons, we compare variation at DOG1 with neutral markers and quantitative variation in seed dormancy. Patterns of genetic differentiation among populations suggest that the gene DOG1 contributes to local adaptation. Although Q ST for seed dormancy is not different from F ST for neutral markers, a correlation with variation in summer precipitation supports that seed dormancy is adaptive. We characterize dormancy variation in several F 2-populations and show that a series of functionally distinct alleles segregate at the DOG1 locus. Theoretical models have shown that the number and effect of alleles segregatin at quantitative trait loci (QTL) have important consequences for adaptation. Our results provide support to models postulating a large number of alleles at quantitative trait loci involved in adaptation. © 2012 The Author(s). Evolution © 2012 The Society for the Study of Evolution.Peer Reviewe

Study of the lineshape of the chi(c1) (3872) state

A study of the lineshape of the chi(c1) (3872) state is made using a data sample corresponding to an integrated luminosity of 3 fb(-1) collected in pp collisions at center-of-mass energies of 7 and 8 TeV with the LHCb detector. Candidate chi(c1)(3872) and psi(2S) mesons from b-hadron decays are selected in the J/psi pi(+)pi(-) decay mode. Describing the lineshape with a Breit-Wigner function, the mass splitting between the chi(c1 )(3872) and psi(2S) states, Delta m, and the width of the chi(c1 )(3872) state, Gamma(Bw), are determined to be (Delta m=185.598 +/- 0.067 +/- 0.068 Mev,)(Gamma BW=1.39 +/- 0.24 +/- 0.10 Mev,) where the first uncertainty is statistical and the second systematic. Using a Flatte-inspired model, the mode and full width at half maximum of the lineshape are determined to be (mode=3871.69+0.00+0.05 MeV.)(FWHM=0.22-0.04+0.13+0.07+0.11-0.06-0.13 MeV, ) An investigation of the analytic structure of the Flatte amplitude reveals a pole structure, which is compatible with a quasibound D-0(D) over bar*(0) state but a quasivirtual state is still allowed at the level of 2 standard deviations

Measurement of the CKM angle γγ in B±→DK±B^\pm\to D K^\pm and B±→Dπ±B^\pm \to D π^\pm decays with D→KS0h+h−D \to K_\mathrm S^0 h^+ h^-

A measurement of $CP$-violating observables is performed using the decays $B^\pm\to D K^\pm$ and $B^\pm\to D \pi^\pm$, where the $D$ meson is reconstructed in one of the self-conjugate three-body final states $K_{\mathrm S}\pi^+\pi^-$ and $K_{\mathrm S}K^+K^-$ (commonly denoted $K_{\mathrm S} h^+h^-$). The decays are analysed in bins of the $D$-decay phase space, leading to a measurement that is independent of the modelling of the $D$-decay amplitude. The observables are interpreted in terms of the CKM angle $\gamma$. Using a data sample corresponding to an integrated luminosity of $9\,\text{fb}^{-1}$ collected in proton-proton collisions at centre-of-mass energies of $7$, $8$, and $13\,\text{TeV}$ with the LHCb experiment, $\gamma$ is measured to be $\left(68.7^{+5.2}_{-5.1}\right)^\circ$. The hadronic parameters $r_B^{DK}$, $r_B^{D\pi}$, $\delta_B^{DK}$, and $\delta_B^{D\pi}$, which are the ratios and strong-phase differences of the suppressed and favoured $B^\pm$ decays, are also reported

Search for the doubly charmed baryon Xi(+)(cc)

A search for the doubly charmed baryon \u39ecc+ is performed through its decay to the \u39bc+K 12\u3c0+ final state, using proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7, 8 and 13 TeV. The data correspond to a total integrated luminosity of 9 fb 121. No significant signal is observed in the mass range from 3.4 to 3.8 GeV/c2. Upper limits are set at 95% credibility level on the ratio of the \u39ecc+ production cross-section times the branching fraction to that of \u39bc+ and \u39ecc++ baryons. The limits are determined as functions of the \u39ecc+ mass for different lifetime hypotheses, in the rapidity range from 2.0 to 4.5 and the transverse momentum range from 4 to 15 GeV/c

(U)pdated measurement of decay-time-dependent CP asymmetries in D-0 -> K+ K- and D-0 -> pi(+)pi(-) decays

A search for decay-time-dependent charge-parity (CP) asymmetry in D0\u2192K+K- A nd D0\u2192\u3c0+\u3c0-decays is performed at the LHCb experiment using proton-proton collision data recorded at a center-of-mass energy of 13 TeV, and corresponding to an integrated luminosity of 5.4 fb-1. The D0 mesons are required to originate from semileptonic decays of b hadrons, such that the charge of the muon identifies the flavor of the neutral D meson at production. The asymmetries in the effective decay widths of D0 and D0 mesons are determined to be A\u393(K+K-)=(-4.3\ub13.6\ub10.5) 710-4 and A\u393(\u3c0+\u3c0-)=(2.2\ub17.0\ub10.8) 710-4, where the uncertainties are statistical and systematic, respectively. The results are consistent with CP symmetry and, when combined with previous LHCb results, yield A\u393(K+K-)=(-4.4\ub12.3\ub10.6) 710-4 and A\u393(\u3c0+\u3c0-)=(2.5\ub14.3\ub10.7) 710-4

Precision measurement of the Xi(++)(cc) mass

A measurement of the \u39ecc++ mass is performed using data collected by the LHCb experiment between 2016 and 2018 in pp collisions at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5.6 fb 121. The \u39ecc++ candidates are reconstructed via the decay modes \u39ecc++\u2192\u39bc+K 12\u3c0+\u3c0+ and \u39ecc++\u2192\u39ec+\u3c0+. The result, 3621.55 \ub1 0.23 (stat) \ub1 0.30 (syst) MeV/c2, is the most precise measurement of the \u39ecc++ mass to date. [Figure not available: see fulltext.]

Measurement of the eta(c)(1S) production cross-section in p p collisions at root s=13TeV

Using a data sample corresponding to an integrated luminosity of 2.0 fb-1, collected by the LHCb experiment, the production of the \u3b7c(1 S) state in proton\u2013proton collisions at a centre-of-mass energy of s=13TeV is studied in the rapidity range 2.0 < y< 4.5 and in the transverse momentum range 6.5<14.0GeV. The cross-section for prompt production of \u3b7c(1 S) mesons relative to that of the J/ \u3c8 meson is measured using the pp\uaf decay mode and is found to be \u3c3\u3b7c(1S)/\u3c3J/\u3c8=1.69\ub10.15\ub10.10\ub10.18. The quoted uncertainties are, in order, statistical, systematic and due to uncertainties on the branching fractions of the J/\u3c8\u2192pp\uaf and \u3b7c\u2192pp\uaf decays. The prompt \u3b7c(1 S) production cross-section is determined to be \u3c3\u3b7c(1S)=1.26\ub10.11\ub10.08\ub10.14\u3bcb, where the last uncertainty includes that on the J/ \u3c8 meson cross-section. The ratio of the branching fractions of b-hadron decays to the \u3b7c(1 S) and J/ \u3c8 states is measured to be Bb\u2192\u3b7cX/Bb\u2192J/\u3c8X=0.48\ub10.03\ub10.03\ub10.05, where the last uncertainty is due to those on the branching fractions of the J/\u3c8\u2192pp\uaf and \u3b7c\u2192pp\uaf decays. The difference between the J/ \u3c8 and \u3b7c(1 S) masses is also determined to be 113.0\ub10.7\ub10.1MeV, which is the most precise single measurement of this quantity to date

First Observation of Excited Omega(-)(b) States

We report four narrow peaks in the \u39eb0K- mass spectrum obtained using pp collisions at center-of-mass energies of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of 9 fb-1 recorded by the LHCb experiment. Referring to these states by their mass, the mass values are m[\u3c9b(6316)-]=6315.64\ub10.31\ub10.07\ub10.50 MeV, m[\u3c9b(6330)-]=6330.30\ub10.28\ub10.07\ub10.50 MeV, m[\u3c9b(6340)-]=6339.71\ub10.26\ub10.05\ub10.50 MeV, m[\u3c9b(6350)-]=6349.88\ub10.35\ub10.05\ub10.50 MeV, where the uncertainties are statistical, systematic, and the last is due to the knowledge of the \u39eb0 mass. The natural widths of the three lower mass states are consistent with zero, and the 90% confidence-level upper limits are determined to be \u393[\u3c9b(6316)-]<2.8 MeV, \u393[\u3c9b(6330)-]<3.1 MeV and \u393[\u3c9b(6340)-]<1.5 MeV. The natural width of the \u3c9b(6350)- peak is 1.4-0.8+1.0\ub10.1 MeV, which is 2.5\u3c3 from zero and corresponds to an upper limit of 2.8 MeV. The peaks have local significances ranging from 3.6\u3c3 to 7.2\u3c3. After accounting for the look-elsewhere effect, the significances of the \u3c9b(6316)- and \u3c9b(6330)- peaks are reduced to 2.1\u3c3 and 2.6\u3c3, respectively, while the two higher mass peaks exceed 5\u3c3. The observed peaks are consistent with expectations for excited \u3c9b- resonances

Isospin Amplitudes in Lambda(0)(b) -> J/psi Lambda (Sigma(0)) and Xi(0)(b)-> J/psi Xi(0) (Lambda) Decays

Ratios of isospin amplitudes in hadron decays are a useful probe of the interplay between weak and strong interactions and allow searches for physics beyond the standard model. We present the first results on isospin amplitudes in b-baryon decays, using data corresponding to an integrated luminosity of 8.5 fb-1, collected with the LHCb detector in pp collisions at center of mass energies of 7, 8, and 13 TeV. The isospin amplitude ratio |A1(\u39bb0\u2192J/\u3c8\u3c20)/A0(\u39bb0\u2192J/\u3c8\u39b)|, where the subscript on A indicates the final-state isospin, is measured to be less than 1/21.8 at 95% confidence level. The Cabibbo suppressed \u39eb0\u2192J/\u3c8\u39b decay is observed for the first time, allowing for the measurement |A0(\u39eb0\u2192J/\u3c8\u39b)/A1/2(\u39eb0\u2192J/\u3c8\u39e0)|=0.37\ub10.06\ub10.02, where the uncertainties are statistical and systematic, respectively

Measurement of vertical bar V-cb vertical bar with B-s(0) -> D-s(()*()-) mu(+)nu(mu) decays

The element |Vcb| of the Cabibbo-Kobayashi-Maskawa matrix is measured using semileptonic Bs0 decays produced in proton-proton collision data collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3 fb-1. Rates of Bs0\u2192Ds-\u3bc+\u3bd\u3bc and Bs0\u2192Ds 17-\u3bc+\u3bd\u3bc decays are analyzed using hadronic form-factor parametrizations derived either by Caprini, Lellouch and Neubert (CLN) or by Boyd, Grinstein and Lebed (BGL). The measured values of |Vcb| are (41.4\ub10.6\ub10.9\ub11.2) 710-3 and (42.3\ub10.8\ub10.9\ub11.2) 710-3 in the CLN and BGL parametrization, respectively. The first uncertainty is statistical, the second systematic, and the third is due to the external inputs used in the measurement. These results are in agreement with those obtained from decays of B+ and B0 mesons. They are the first determinations of |Vcb| at a hadron-collider experiment and the first using Bs0 meson decays