Image, cuerpo y lenguaje en usos de la aplicación Grindr

Le présent travail discute l’application de recontres pour hommes Grindr, dans ses aspects linguistique et sémiotique, en mettant l’accent sur les productions imaginaires et linguistiques de ses utilisateurs, conçues comme des performativités. Onze hommes qui utilisent ce réseau social ont été interviewés, en se concentrant sur leurs compositions photographiques et leurs interactions textuelles avec les autres membres, analysées par la suite dans les cadres des perspectives butlerienne et barthesiennes sur la langue et sa relation avec l’image. On a identifié la composition d’une “grammaire” produite à l’intérieur de l’application, avec une signification particulière des mots et des images, avec ciblage commercial et médiatique. En outre, les interviewés ont abordé les techniques de composition et de manipulation des photographies, les modulations corporelles et l’association de pratiques enfermées dans l’application à une dimension politique. Ainsi, il a été possible de comprendre le Grindr comme un “système de signification” où ces dynamiques sont produites, négociées et contestées dans leur propre usage.El presente artículo discute la aplicación de citas entre hombres Grindr, en sus aspectos linguísticos y semióticos, enfatizando las producciones de imágenes y lenguaje de sus usuarios, comprendidas como performatividades. Once hombres usuarios de Grindr fueron entrevistados, con foco en sus composiciones fotográficas y interacciones textuales con otros miembros de la red social, posteriormente analizadas a partir de las perspectivas butlerianas y barthesianas sobre el lenguaje y sus relaciones con la imagen. Se constató la producción de una “gramática” en el interior de la aplicación, con la significación particular de palabras y imágenes com dirección comercial y mediatica. Además, técnicas de composición y manipulación de fotografías, modulaciones del cuerpo y la asociación entre prácticas en la aplicación a cuestiones políticas fueron abordadas por los entrevistados. De esta manera, fue posible comprender Grindr como un “sistema de significación”, dónde estas dinámicas son producidas, negociadas y disputadas en sus usos.In our study we discuss the gay dating app Grindr, considering its linguistic and semiotic aspects, emphasizing its users’ imagery and linguistic productions, conceived as performativities. Eleven users of this social network were interviewed, focusing on their photographic compositions and textual interactions with other members, subsequently analyzed under Butlerian and Barthesian perspectives on language and its relation to image. A “grammar” with particular meanings of words and images with commercial and mediatic target was found out to be used within the application. Furthermore, techniques of photography, body improvement, and associations between practices and political issues were addressed by the interviewees. Therefore, we could understand Grindr as a “meaning system”, where such dynamics are produced, negotiated and disputed in its uses.O presente artigo aborda o aplicativo de busca por parceiros entre homens Grindr, em seus aspectos linguísticos e semióticos, enfatizando as produções imagéticas e discursivas de seus usuários, concebidas enquanto performatividades. Foram entrevistados onze homens que utilizam a rede social, com foco em suas composições fotográficas e interações textuais com outros membros do aplicativo, analisadas posteriormente a partir das perspectivas butlerianas e barthesianas sobre a linguagem e sua interface com a imagem. Constatouse a composição de uma “gramática” produzida no interior do aplicativo, com significação particular de palavras e imagens e direcionamento comercial e midiático. Além disso, técnicas de composição e manipulação de fotografias, modulações do corpo e associação de práticas travadas no aplicativo a uma dimensão política foram abordadas pelos entrevistados. Desta forma, foi possível entender o Grindr como um “sistema de significação”, no qual tais dinâmicas são produzidas, negociadas e disputadas no seu próprio uso

Challenges on the Follow-Up Experimental Leptospiral Infection in Sheep

Background: Leptospirosis is currently a source of significant economic losses in the agribusiness; as such, experimental studies on this infection are required to develop a better understanding of the pathogenesis, treatment, and immunoprophylaxis of the disease. Sheep may represent a good model for ruminants in such models. Despite the extent of the studies that has been conducted thus far, researchers have yet to reach a consensus on the experimental practices to apply for leptospirosis in this animal species, and several gaps in understanding remain. To bridge these gaps, the present study aimed to assess the usage of several tools for the monitoring of experimental leptospirosis in sheep.Material, Methods & Results: Twelve Santa Ines sheep of different ages were each allocated to one of four groups (A, B, C, and D). The subjects in groups A, B, and C received different doses of Leptospira interrogans serogroup Icterohemorrhagiae by intraperitoneal route, 1x102, 1x105, and 1x108 respectively. Group D was the control. Hematological, biochemical and clinical parameters were evaluated daily. Serology by microscopic agglutination test (MAT) and PCR were performed to evaluate the infection status. The most remarkable clinical signs were fever (41ºC) and dehydration, and acute pain (cub). Two animals from Group C presented leukocytosis. Only those in Group C exhibited positive results according to serology, while positivity in PCR was observed in animals in groups A and C. The results of the experiment indicated that sheep may be experimentally infected and can, therefore, be used as a model for leptospirosis in ruminants. Clinical signs cannot be considered to represent a reliable parameter for evaluating the development of leptospirosis in experimentally infected sheep. We recommend the use of urine PCR and serology to confirm the infection in experimentally infected animals and daily complete blood count (CBC) as a follow-up tool.Discussion: It was observed that the clinical signs cannot be considered as a reliable parameter to evaluate the pathogenesis in experimentally infected ewes, being important to emphasize that the age of the animals does not seem to alter their susceptibility to the infection. This finding is in agreement with other experimental studies, which report that leptospirosis infection in ruminants occurs asymptomatic and subclinical. Hematological and biochemical tests proved to be adequate tools to monitor the experimental infection. Studies have shown that the complete blood count has been used to monitor the acute phase of leptospirosis and is effective in detecting anemia and leukocytosis with neutrophilia in ruminants. Despite the lack of clinical signs, the serological and molecular results confirmed the experimental infection. PCR has been used as an important tool in the diagnosis of leptospirosis. In addition, the current study is the first of its kind to use PCR to detect the carrier status in experimentally infected ewes. Despite this limitation, PCR was very effective in confirming the infection and should be considered for use in experimental studies. Sheep have been used as a good experimental model in several studies, sheep are relatively small compared to other ruminants and can be easily allocated in smaller pens and pens, facilitating the management of research and minimizing the costs of experimentation. In this context, we suggest that sheep represent a good model for the study of leptospirosis in ruminants and therefore a reliable protocol for experimental infection by leptospirosis is necessary

O QUE NOS REVELAM AS PESQUISAS SOBRE O ENSINO DE ASTRONOMIA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL?

Este trabalho apresenta uma reflexão sobre o ensino de Astronomia e tem como objetivo analisar a abrangência do ensino de Astronomia na infância a partir das pesquisas publicadas nas atas do Encontro Nacional de Pesquisa em Educação em Ciências (ENPEC). Para tanto, foi utilizado como metodologia de pesquisa o Estado da Arte para mapear os trabalhos publicados nos últimos dez anos. Foram analisados 17 trabalhos que oportunizaram a produção dos dados que, pelos quais, foi possível verificar as principais tendências de temáticas dentro do ensino da Astronomia, assim como algumas temáticas que precisam de uma maior visibilidade e atenção, sobretudo nos primeiros anos da infância

Chemical and antimicrobial analysis of husk fiber aqueous extract from Cocos nucifera L.

Cocos nucifera L. (Arecaceae) is a widely distributed species around the tropical areas. Popular uses have been reported in the treatment of arthritis and diarrhea. This study evaluates the antimicrobial activity of husk fiber aqueous extract from C. nucifera and performed the identification of some biological active substances. The minimal inhibitory concentration (MIC) against human pathogen microorganisms was determined. Chromatographic and spectrometric procedures were also performed to isolate and identify the components present in the extract. In the MIC assay of crude aqueous extract, only the methicillin sensible and the resistant (MRSA) Staphylococcus aureus strains were susceptible at 156 μg/mL. The ethyl acetate partition taken from crude extract was more promising (MIC of 78 μg/mL). No fungal growth inhibition was observed. Catechin, epicatechin, two procyanidin dimers and condensed tannins were found in the organic phase. In addition, gallic and ellagic acids were detected for the first time in C. nucifera husk fiber. Gallic acid showed MIC of 39 μg/mL and minimal bactericidal concentration (MBC) at 78 μg/mL. Ellagic acid was not active against the tested strains, as well as catechin and epicatechin. Additionally catechin, epicatechin, two procyanidin dimers and condensed tannins were also detected. The antimicrobial activity observed was selective to S. aureus strains.Keywords: Antimicrobial analyses, Cocos nucifera, arecaceae, ellagic acid, gallic acid, procyanidins, Staphylococcus aureus strainsAfrican Journal of Biotechnology Vol. 12(18), pp. 2478-248

The beneficial effects of a water-based aerobic exercise session on the blood lipids of women with dyslipidemia are independent of their training status

OBJECTIVES: To evaluate the acute effects of a session of water-based aerobic exercise on the blood lipid levels of women with dyslipidemia and to compare these results according to their training status. METHOD: Fourteen premenopausal women with dyslipidemia, aged 40–50 years, participated in two waterbased aerobic exercise sessions, the first when they were generally sedentary and the second after they were trained with a water-based aerobic training program for 12 weeks. Both experimental sessions were performed using the same protocol, lasted 45 min, and incorporated an interval method, alternating 3 min at a rating of perceived exertion (RPE) of 13 and 2 min at an RPE of 9. Total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and lipoprotein lipase enzyme (LPL) were obtained through venous blood collection before and immediately after each session. A generalized estimating equation method and Bonferroni tests were conducted (with time and training status as factors) for statistical analyses. RESULTS: At enrollment, the mean age of the participants was 46.57 years (95% confidence interval [CI] 44.81– 48.34). The statistical analyses showed a significant time effect for all variables (TC: p=0.008; TG: p=0.012; HDL: po0.001; LPL: po0.001) except for LDL (p=0.307). However, the training status effect was not significant for any variable (TC: p=0.527; TG: p=0.899; HDL: p=0.938; LDL: p=0.522; LPL: p=0.737). These results indicate that the TC and TG levels reduced and the HDL and LPL concentrations increased from pre- to post-session in similar magnitudes in both sedentary and trained women. CONCLUSIONS: A single water-based aerobic exercise session is sufficient and effective to beneficially modify the lipid profile of women with dyslipidemia, regardless of their training status

HISTÓRIA E FILOSOFIA DA BIOLOGIA E O ENSINO: PENSANDO UMA ABORDAGEM A PARTIR DA PEDAGOGIA HISTÓRICO-CRÍTICA

Este artigo é parte de um trabalho de iniciação científica intitulado “História e a Filosofia da Biologia na Educação Básica – os estatutos do conhecimento biológico nas publicações do periódico Filosofia e História da Biologia e suas potencialidades para o ensino”. A pesquisa tem fundamentação materialista histórico-dialética e parte de uma revisão sistemática para analisar as relações entre a História e Filosofia da Biologia (HFB) e o Ensino de Biologia (EB), estabelecidas nos artigos publicados pelo periódico da Associação Brasileira Filosofia e História da Biologia (ABFHiB), um dos mais relevantes do Brasil no que diz respeito à temática. Em nossa análise, percebemos que há dois grandes grupos de propostas de abordagens para articulação entre a HFB e o EB: a abordagem integradora e a abordagem contextualizadora. Também percebemos dois elementos que atravessam as produções: a centralidade no conhecimento e a ausência de teoria pedagógica, que acabam negando a especificidade do conhecimento escolar. Assim, reconhecemos que apesar dos avanços e dos benefícios pedagógicos que a HFB fornece ao EB, este campo de conhecimento ainda carece de articulações mais profundas com os conhecimentos de natureza pedagógica, visto que a HFB por si só não se constitui enquanto um referencial pedagógico autônomo. Por fim, visando avanços, superações e reelaborações, lançamo-nos ao desafio, ainda que embrionário, de pensar uma abordagem histórico-filosófica para o EB a partir da Pedagogia Histórico-Crítica

Audiência de custódia virtual como forma de otimização do procedimento: eficiência e celeridade na garantia dos direitos fundamentais / Virtual custody hearing as a way to optimize the procedure: efficiency and speed in guaranteeing fundamental rights

O presente artigo possui o enfoque na possibilidade da realização de audiências de custódia através de video conferências. Ainda que a temática não seja novidade, com o advento da pandemia, a possibilidade ganhou um novo olhar ao pensar no impacto que a pandemia trouxe. Pensar nessa possibilidade é assegurar ao preso que seu direito fundamental além da análise, e possibilidade, de reanálise dos requisitos do auto de prisão em flagrante

Systems and Synthetic Biology Approaches to Engineer Fungi for Fine Chemical Production

Since the advent of systems and synthetic biology, many studies have sought to harness microbes as cell factories through genetic and metabolic engineering approaches. Yeast and filamentous fungi have been successfully harnessed to produce fine and high value-added chemical products. In this review, we present some of the most promising advances from recent years in the use of fungi for this purpose, focusing on the manipulation of fungal strains using systems and synthetic biology tools to improve metabolic flow and the flow of secondary metabolites by pathway redesign. We also review the roles of bioinformatics analysis and predictions in synthetic circuits, highlighting in silico systemic approaches to improve the efficiency of synthetic modules

SARS-COV-2 AND ARBOVIRUS INFECTIONS: PROTOCOL FOR A RAPID LIVING SYSTEMATIC REVIEW

Context and objective: While cases of COVID-19 disease increase daily worldwide, outbreaks of arboviral infections have affected health systems of countries in tropical regions. The outcomes for patients and health systems of a possible syndemic are not clarified yet. Thus, we aim to systematically review the literature searching for evidence that describes the clinical presentation, severity and prognostic of SARS-CoV-2 and Arboviral coinfection. Design and setting: Protocol for a rapid living systematic review, that will follow the Cochrane Handbook for Systematic Reviews recommendations. We will include prospective and retrospective cohort, case-control studies and case series of patients with confirmed diagnosis of SARS-CoV-2 and Arboviral infection. We will perform the search strategy with no language restrictions on Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS - LILACS, Scopus and WebOfScience to identify published, ongoing, and unpublished studies. The selection and extraction will be performed by two authors. We will perform the critical appraisal of included studies with the Newcastle-Ottawa Scale and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).   &nbsp

Como a COVID-19 mudou a forma de educação: um relato de experiência

RESUMO: A COVID-19 é uma doença infeciosa causada pelo coronavírus da Síndrome Respiratória Aguda Grave 2 (SARS-CoV-2), com os sintomas mais comuns sendo febre, tosse secae cansaço. A pandemia gerada por esta doença obrigou o mundo a se transfigurar, alterandoa maneira de viver de bilhões de pessoas, principalmente pelo distanciamento social, buscando uma redução na propagação do vírus. Todas as alterações atingiram diretamente ocenário educacional mundial, influenciando assim na forma como os estudantes de todas asidades frequentam as aulas e interagem, além dos professores, que se veem na necessidadede se adaptar mais rapidamente para prover a educação da melhor maneira para seus alunos,sendo sempre necessário um grande esforço de ambos os lados. Essa nova necessidade dediferentes métodos educacionais abriu as portas para aulas online, além de estruturar de maneira mais consistente o estilo de Educação a Distância (EAD) e outros métodos utilizados noestado de Goiás. O objetivo deste artigo é relatar a experiência dos acadêmicos de medicinada UniEVANGÉLICA e citar a experiência dos acadêmicos de medicina de outras instituiçõesgoianas durante o período da quarentena da COVID-19, na qual buscou-se mostrar as dificuldades frente à nova metodologia de ensino não presencial. Foi exposta a maneira como oCentro Universitário de Anápolis e outras faculdades de Goiás conseguiram manter os estudantes de medicina tendo aulas e atividades por meio do mundo online que por fim, se mostraram incapazes de suprir algumas das necessidades dos estudantes de medicina