Teoría de la ruina y aplicaciones prácticas

Treballs Finals de Grau de Matemàtiques, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2019, Director: Josep Vives i Santa Eulàlia[en] For the insurers, the calculation of their probability of ruin depends on random phenomena. This research aims to find a methodology for the determination of the ruin probability of an insurance company. Furthermore, this research aims to apply the results in some practical cases. For the explained above, it is going to be developed a Ruin Theory, under different models for the cash flow, in terms of the number of claims and its amount. Specifically, there are going to be explained the Classical and Renewal Models of Cramér-Lundberg and the Net Profit Condition. These will be the assumptions un- der which an explicit equation can be given for the probability of ruin or a limit to approximate it. Finally, all of the above will be applied assuming a distribution function for the amount of claims. It is going to be analyzed how the probability of Ruin is affected against the variation of the initial capital or the security surcharge for infinite time and it is going to be simulated some data to approximate the probability of Ruin in a finite time

Análisis de la expresión de TLR7 en pacientes con Lupus Eritematoso Sistémico e infección viral previa

El lupus eritematoso sistémico (LES) es una enfermedad autoinmune sistémica crónica. En su patogénesis intervienen los receptores Toll-like (TLR) 7 y 9, que activan las vías de interferón e intervienen en la respuesta inmune frente a virus. El objetivo consiste en analizar la posible asociación entre niveles séricos de TLR7 y las infecciones virales previas en pacientes con LES.Systemic Lupus Erythematous (SLE) is a chronic, inflammatory, systemic autoimmune disease. Its pathogeny is due to, between others, toll like receptor (TLR) 7 and 9, which activate an interferon response. Furthermore, they are responsible for the immune response against viruses. The objective is to analyse the possible association between TL7 serum concentration and viral infections in patients diagnosed with SLEMedicin

Novena campanya d'excavacions a la ciutat romana de Lesera

En aquesta nota presentem un avanç dels resultats de la campanya d'excavacions de 2015 realitzada a la ciutat romana de Lesera, que fou finançada per la Mancomunitat Comarcal dels Ports en el marc del Pla Formatiu d'auxiliars en Arqueologia del Taller d'Ocupació, i es desenvolupà de manera discontínua entre els dies 16 de març i 22 de juliol. Les excavacions es feren en el marc de les pràctiques dels alumnes d'aquest taller1. L'actuació consistí en la continuació dels treballs començats en els anys 2008-2009 als sondeigs 6 i 8 (Arasa 2009a), situats al sector N de la plataforma inferior del jaciment. Les conclusions que exposem tenen un caràcter provisional, atés que encara no ha finalitzat l'estudi dels materials recuperats

Gastos Médicos en España: Estimaciones del Sistema de Demanda Casi Ideal y del Modelo de Rotterdam

En este estudio analizamos los Gastos Médicos en España desde una perspectiva micro-econométrica. Observamos que el modelo microeconómico que mejor se asemeja con las preferencias de los consumidores españoles para los años 1980 a 2015 es el modelo Rotterdam dinámico y obtenemos una serie de valores para describir cómo se comporta el consumidor en la realidad.Las distintas categorías de Gastos Médicos presentan elasticidades totalmente diferentes. Vemos que gracias a la inversión pública, los productos médicos han pasado a comportarse como bienes de primera necesidad, mientras que la elasticidad de servicios y hospital ha aumentado. Sobre el análisis de las elasticidades precio, las elasticidades Marshallianas nos permiten constatar bienes complementarios brutos, mientras que las elasticidades precio Hicksianas nos confirman que los Gastos Médicos son sustitutivos netos

Gastos Médicos en España: Estimaciones del Sistema de Demanda Casi Ideal y del Modelo de Rotterdam

En este estudio analizamos los Gastos Médicos en España desde una perspectiva micro-econométrica. Observamos que el modelo microeconómico que mejor se asemeja con las preferencias de los consumidores españoles para los años 1980 a 2015 es el modelo Rotterdam dinámico y obtenemos una serie de valores para describir cómo se comporta el consumidor en la realidad.Las distintas categorías de Gastos Médicos presentan elasticidades totalmente diferentes. Vemos que gracias a la inversión pública, los productos médicos han pasado a comportarse como bienes de primera necesidad, mientras que la elasticidad de servicios y hospital ha aumentado. Sobre el análisis de las elasticidades precio, las elasticidades Marshallianas nos permiten constatar bienes complementarios brutos, mientras que las elasticidades precio Hicksianas nos confirman que los Gastos Médicos son sustitutivos netos

Bent-core liquid crystalline cyanostilbenes : fluorescence switching and thermochromism

The authors from ICMA greatly appreciate financial support from the Spanish Government (MINECO-FEDER project MAT2012-38538-C03-01), the Aragon's Government and FSE (project E04) and the Jae PreDoc-CSIC (M. M.-A.) fellowship program.Fluorescent bent-core molecules, bearing one or two cyanostilbene units in the lateral structure and different positions of the cyano group (α- or β-isomers), are described with the aim of modulating the molecular packing and fluorescence properties. These compounds give rise to a variety of crystal polymorphs and bent-core liquid crystalline phases (SmCP, Colr and B6), offering the unique chance to study the fluorescence properties of the cyanostilbene structure in different phases. Experimental and computational studies elucidate geometrical and electronic properties of these bent-core structures but especially the fluorescence properties (spectral positions, quantum yields and decay curves), in a detailed comparison between diluted solutions, in dichloromethane (DCM) or poly(methylmethacrylate) (PMMA), and condensed phases. Quantum yields as high as 70% have been obtained in some diluted solutions (PMMA) and condensed phases. Remarkably, the quantum yield values depend on the position of the cyano group, being higher for β- than for the α-isomers due to the higher radiative rates and lower non-radiative rates of the former. The photophysical characterization in the condensed phase focuses on RT studies with solid samples and different processing, and show that, upon aggregation, interactions between the cyanostilbene groups result in changes of the emission spectra and dynamics compared to the diluted systems in DCM and PMMA, giving rise to H-aggregations of varying strength. Furthermore, the compounds exhibit thermochromism, showing a green-yellow fluorescence in the pristine crystalline phase that changes to blue on heating to the liquid crystal phase. This journal isPostprintPeer reviewe

Fatty Acid Signatures in Different Tissues of Mediterranean Yellowtail, Seriola dumerili (Risso, 1810), Fed Diets Containing Different Levels of Vegetable and Fish Oils

[EN] The study aimed to evaluate how replacing different proportions of fish oil (FO) with vegetable oils (VO) in the diet of Mediterranean yellowtail, Seriola dumerili (Risso, 1810), affects the fatty acids (FA) signature, i.e.; overall FA profile, in different tissues. A total of 225 Mediterranean yellowtail juveniles (initial live weight: 176 ± 3.62 g) were fed for 109 days with one of three diets: A control diet (FO 100), with FO as the only lipid source, or diets with 75% and 100% of FO replaced with a VO mixture. At the end of the feeding trial, the brains, muscles, livers, and visceral fat were sampled in four fish per tank (12 per treatment), and their fat were extracted and used for FA analysis. The FA signatures of red and white muscle, liver, and visceral fat tissues changed when the dietary FA source changed, whereas FA signatures in the brain were rather robust to such dietary changes. These new insights might help evaluate whether key physiological functions are preserved when fish are fed diets with low FO levels, as well as define the dietary FA requirements of Mediterranean yellowtail to improve the sustainability of the production and welfare of the fish.The Ph.D. grant held by Francesco Bordignon is funded by the ECCEAQUA project (MIUR; CUP: C26C18000030004).Bordignon, F.; Tomas-Vidal, A.; Trocino, A.; Milián-Sorribes, MC.; Jover Cerda, M.; Martínez-Llorens, S. (2020). Fatty Acid Signatures in Different Tissues of Mediterranean Yellowtail, Seriola dumerili (Risso, 1810), Fed Diets Containing Different Levels of Vegetable and Fish Oils. Animals. 10(2):1-16. https://doi.org/10.3390/ani10020198S116102Matsunari, H., Hashimoto, H., Oda, K., Masuda, Y., Imaizumi, H., Teruya, K., … Mushiake, K. (2012). Effects of docosahexaenoic acid on growth, survival and swim bladder inflation of larval amberjack (Seriola dumerili, Risso). Aquaculture Research, n/a-n/a. doi:10.1111/j.1365-2109.2012.03174.xGrau, A., Riera, F., & Carbonell, E. (1999). Aquaculture International, 7(5), 307-317. doi:10.1023/a:1009212520021Sicuro, B., & Luzzana, U. (2016). The State ofSeriola spp.Other Than Yellowtail (S. quinqueradiata) Farming in the World. Reviews in Fisheries Science & Aquaculture, 24(4), 314-325. doi:10.1080/23308249.2016.1187583Mazzola, A., Favaloro, E., & Sarà, G. (2000). Cultivation of the Mediterranean amberjack, Seriola dumerili (Risso, 1810), in submerged cages in the Western Mediterranean Sea. Aquaculture, 181(3-4), 257-268. doi:10.1016/s0044-8486(99)00243-4Jover, M., Garcı́a-Gómez, A., Tomás, A., De la Gándara, F., & Pérez, L. (1999). Growth of mediterranean yellowtail (Seriola dumerilii) fed extruded diets containing different levels of protein and lipid. Aquaculture, 179(1-4), 25-33. doi:10.1016/s0044-8486(99)00149-0Takakuwa, F., Fukada, H., Hosokawa, H., & Masumoto, T. (2006). Optimum digestible protein and energy levels and ratio for greater amberjack Seriola dumerili (Risso) fingerling. Aquaculture Research, 37(15), 1532-1539. doi:10.1111/j.1365-2109.2006.01590.xVidal, A. T., De la Gándara García, F., Gómez, A. G., & Cerdá, M. J. (2008). Effect of the protein/energy ratio on the growth of Mediterranean yellowtail (Seriola dumerili). Aquaculture Research, 39(11), 1141-1148. doi:10.1111/j.1365-2109.2008.01975.xPapadakis, I. E., Chatzifotis, S., Divanach, P., & Kentouri, M. (2007). Weaning of greater amberjack (Seriola dumerilii Risso 1810) juveniles from moist to dry pellet. Aquaculture International, 16(1), 13-25. doi:10.1007/s10499-007-9118-xHaouas, W. G., Zayene, N., Guerbej, H., Hammami, M., & Achour, L. (2010). Fatty acids distribution in different tissues of wild and reared Seriola dumerili. International Journal of Food Science & Technology, 45(7), 1478-1485. doi:10.1111/j.1365-2621.2010.02292.xMonge-Ortiz, R., Tomás-Vidal, A., Rodriguez-Barreto, D., Martínez-Llorens, S., Pérez, J. A., Jover-Cerdá, M., & Lorenzo, A. (2017). Replacement of fish oil with vegetable oil blends in feeds for greater amberjack (Seriola dumerili) juveniles: Effect on growth performance, feed efficiency, tissue fatty acid composition and flesh nutritional value. Aquaculture Nutrition, 24(1), 605-615. doi:10.1111/anu.12595Mourente, G., Tocher, D. R., & Sargent, J. R. (1991). Specific accumulation of docosahexaenoic acid (22∶6n−3) in brain lipids during development of juvenile turbotScophthalmus maximus L. Lipids, 26(11), 871-877. doi:10.1007/bf02535970Sargent, J., Bell, G., McEvoy, L., Tocher, D., & Estevez, A. (1999). Recent developments in the essential fatty acid nutrition of fish. Aquaculture, 177(1-4), 191-199. doi:10.1016/s0044-8486(99)00083-6Tocher, D. R., & Harvie, D. G. (1988). Fatty acid compositions of the major phosphoglycerides from fish neural tissues; (n−3) and (n−6) polyunsaturated fatty acids in rainbow trout (Salmo gairdneri) and cod (Gadus morhua) brains and retinas. Fish Physiology and Biochemistry, 5(4), 229-239. doi:10.1007/bf01874800Bell, J. G., Castell, J. D., Tocher, D. R., MacDonald, F. M., & Sargent, J. R. (1995). Effects of different dietary arachidonic acid : docosahexaenoic acid ratios on phospholipid fatty acid compositions and prostaglandin production in juvenile turbot (Scophthalmus maximus). Fish Physiology and Biochemistry, 14(2), 139-151. doi:10.1007/bf00002457Sargent, J. R., McEvoy, L. A., & Bell, J. G. (1997). Requirements, presentation and sources of polyunsaturated fatty acids in marine fish larval feeds. Aquaculture, 155(1-4), 117-127. doi:10.1016/s0044-8486(97)00122-1Tocher, D. R., & Ghioni, C. (1999). Fatty acid metabolism in marine fish: Low activity of fatty acyl Δ5 desaturation in gilthead sea bream (Sparus aurata) cells. Lipids, 34(5), 433-440. doi:10.1007/s11745-999-0382-8Turchini, G. M., Torstensen, B. E., & Ng, W.-K. (2009). Fish oil replacement in finfish nutrition. Reviews in Aquaculture, 1(1), 10-57. doi:10.1111/j.1753-5131.2008.01001.xIverson, S. J., Field, C., Don Bowen, W., & Blanchard, W. (2004). QUANTITATIVE FATTY ACID SIGNATURE ANALYSIS: A NEW METHOD OF ESTIMATING PREDATOR DIETS. Ecological Monographs, 74(2), 211-235. doi:10.1890/02-4105James Henderson, R., & Tocher, D. R. (1987). The lipid composition and biochemistry of freshwater fish. Progress in Lipid Research, 26(4), 281-347. doi:10.1016/0163-7827(87)90002-6Furuita, H., Takeuchi, T., & Uematsu, K. (1998). Effects of eicosapentaenoic and docosahexaenoic acids on growth, survival and brain development of larval Japanese flounder (Paralichthys olivaceus). Aquaculture, 161(1-4), 269-279. doi:10.1016/s0044-8486(97)00275-5Anderson, G. J., Connor, W. E., & Corliss, J. D. (1990). Docosahexaenoic Acid Is the Preferred Dietary n-3 Fatty Acid for the Development of the Brain and Retina. Pediatric Research, 27(1), 89-97. doi:10.1203/00006450-199001000-00023Bianconi, S., Santillán, M. E., Solís, M. del R., Martini, A. C., Ponzio, M. F., Vincenti, L. M., … Stutz, G. (2018). Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model. The Journal of Nutritional Biochemistry, 61, 82-90. doi:10.1016/j.jnutbio.2018.07.007Thiemann, G. W. (2008). Using fatty acid signatures to study bear foraging: Technical considerations and future applications. Ursus, 19(1), 59-72. doi:10.2192/08per001r.1Kaushik, S. J., Corraze, G., Radunz-Neto, J., Larroquet, L., & Dumas, J. (2006). Fatty acid profiles of wild brown trout and Atlantic salmon juveniles in the Nivelle basin. Journal of Fish Biology, 68(5), 1376-1387. doi:10.1111/j.0022-1112.2006.01005.xStowasser, G., McAllen, R., Pierce, G. J., Collins, M. A., Moffat, C. F., Priede, I. G., & Pond, D. W. (2009). Trophic position of deep-sea fish—Assessment through fatty acid and stable isotope analyses. Deep Sea Research Part I: Oceanographic Research Papers, 56(5), 812-826. doi:10.1016/j.dsr.2008.12.016Budge, S. M., Penney, S. N., & Lall, S. P. (2012). Estimating diets of Atlantic salmon (Salmo salar) using fatty acid signature analyses; validation with controlled feeding studies. Canadian Journal of Fisheries and Aquatic Sciences, 69(6), 1033-1046. doi:10.1139/f2012-039Magnone, L., Bessonart, M., Rocamora, M., Gadea, J., & Salhi, M. (2015). Diet estimation of Paralichthys orbignyanus in a coastal lagoon via quantitative fatty acid signature analysis. Journal of Experimental Marine Biology and Ecology, 462, 36-49. doi:10.1016/j.jembe.2014.10.008Happel, A., Stratton, L., Pattridge, R., Rinchard, J., & Czesny, S. (2016). Fatty‐acid profiles of juvenile lake trout reflect experimental diets consisting of natural prey. Freshwater Biology, 61(9), 1466-1476. doi:10.1111/fwb.12786Benedito-Palos, L., Navarro, J. C., Kaushik, S., & Pérez-Sánchez, J. (2010). Tissue-specific robustness of fatty acid signatures in cultured gilthead sea bream (Sparus aurata L.) fed practical diets with a combined high replacement of fish meal and fish oil1. Journal of Animal Science, 88(5), 1759-1770. doi:10.2527/jas.2009-2564O’Fallon, J. V., Busboom, J. R., Nelson, M. L., & Gaskins, C. T. (2007). A direct method for fatty acid methyl ester synthesis: Application to wet meat tissues, oils, and feedstuffs. Journal of Animal Science, 85(6), 1511-1521. doi:10.2527/jas.2006-491Tocher, D. R. (2010). Fatty acid requirements in ontogeny of marine and freshwater fish. Aquaculture Research, 41(5), 717-732. doi:10.1111/j.1365-2109.2008.02150.xIshizaki, Y., Masuda, R., Uematsu, K., Shimizu, K., Arimoto, M., & Takeuchi, T. (2001). The effect of dietary docosahexaenoic acid on schooling behaviour and brain development in larval yellowtail. Journal of Fish Biology, 58(6), 1691-1703. doi:10.1111/j.1095-8649.2001.tb02323.xFuruita, H., Takeuchi, T., Watanabe, T., Fujimoto, H., Sekiya, S., & Imaizumi, K. (1996). Requirements of Larval Yellowtail for Eicosapentaenoic Acid, Docosahexaenoic Acid, and n-3 Highly Unsaturated Fatty Acid. Fisheries science, 62(3), 372-379. doi:10.2331/fishsci.62.372Masuda, R., Takeuchi, T., Tsukamoto, K., Sato, H., Shimizu, K., & Imaizumi, K. (1999). Incorporation of Dietary Docosahexaenoic Acid into the Central Nervous System of the Yellowtail Seriola quinqueradiata. Brain, Behavior and Evolution, 53(4), 173-179. doi:10.1159/000006592Masuda, R., Takeuchi, T., Tsukamoto, K., Ishizaki, Y., Kanematsu, M., & Imaizum, K. (1998). Critical involvement of dietary docosahexaenoic acid in the ontogeny of schooling behaviour in the yellowtail. Journal of Fish Biology, 53(3), 471-484. doi:10.1111/j.1095-8649.1998.tb00996.xMasuda, R., & Tsukamoto, K. (1999). Environmental Biology of Fishes, 56(1/2), 243-252. doi:10.1023/a:1007565508398Mesa-Rodriguez, A., Hernández-Cruz, C. M., Betancor, M. B., Fernández-Palacios, H., Izquierdo, M. S., & Roo, J. (2017). Effect of increasing docosahexaenoic acid content in weaning diets on survival, growth and skeletal anomalies of longfin yellowtail (Seriola rivoliana,Valenciennes 1833). Aquaculture Research, 49(3), 1200-1209. doi:10.1111/are.13573Nasopoulou, C., & Zabetakis, I. (2012). Benefits of fish oil replacement by plant originated oils in compounded fish feeds. A review. LWT, 47(2), 217-224. doi:10.1016/j.lwt.2012.01.018Bowyer, J. N., Qin, J. G., Smullen, R. P., & Stone, D. A. J. (2012). Replacement of fish oil by poultry oil and canola oil in yellowtail kingfish (Seriola lalandi) at optimal and suboptimal temperatures. Aquaculture, 356-357, 211-222. doi:10.1016/j.aquaculture.2012.05.014Bell, J. G., Strachan, F., Good, J. E., & Tocher, D. R. (2006). Effect of dietary echium oil on growth, fatty acid composition and metabolism, gill prostaglandin production and macrophage activity in Atlantic cod (Gadus morhua L.). Aquaculture Research, 37(6), 606-617. doi:10.1111/j.1365-2109.2006.01470.xStoknes, I. S., Økland, H. M. W., Falch, E., & Synnes, M. (2004). Fatty acid and lipid class composition in eyes and brain from teleosts and elasmobranchs. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 138(2), 183-191. doi:10.1016/j.cbpc.2004.03.009Rodríguez-Barreto, D., Jerez, S., Cejas, J. R., Martin, M. V., Acosta, N. G., Bolaños, A., & Lorenzo, A. (2012). Comparative study of lipid and fatty acid composition in different tissues of wild and cultured female broodstock of greater amberjack (Seriola dumerili). Aquaculture, 360-361, 1-9. doi:10.1016/j.aquaculture.2012.07.013Benedito-Palos, L., Navarro, J. C., Sitjà-Bobadilla, A., Gordon Bell, J., Kaushik, S., & Pérez-Sánchez, J. (2008). High levels of vegetable oils in plant protein-rich diets fed to gilthead sea bream (Sparus aurata L.): growth performance, muscle fatty acid profiles and histological alterations of target tissues. British Journal of Nutrition, 100(5), 992-1003. doi:10.1017/s0007114508966071Piedecausa, M. A., Mazón, M. J., García García, B., & Hernández, M. D. (2007). Effects of total replacement of fish oil by vegetable oils in the diets of sharpsnout seabream (Diplodus puntazzo). Aquaculture, 263(1-4), 211-219. doi:10.1016/j.aquaculture.2006.09.039Richard, N., Mourente, G., Kaushik, S., & Corraze, G. (2006). Replacement of a large portion of fish oil by vegetable oils does not affect lipogenesis, lipid transport and tissue lipid uptake in European seabass (Dicentrarchus labrax L.). Aquaculture, 261(3), 1077-1087. doi:10.1016/j.aquaculture.2006.07.021BOURAOUI, L., SÁNCHEZ-GURMACHES, J., CRUZ-GARCIA, L., GUTIÉRREZ, J., BENEDITO-PALOS, L., PÉREZ-SÁNCHEZ, J., & NAVARRO, I. (2010). Effect of dietary fish meal and fish oil replacement on lipogenic and lipoprotein lipase activities and plasma insulin in gilthead sea bream (Sparus aurata). Aquaculture Nutrition, 17(1), 54-63. doi:10.1111/j.1365-2095.2009.00706.xRegost, C., Arzel, J., Robin, J., Rosenlund, G., & Kaushik, S. . (2003). Total replacement of fish oil by soybean or linseed oil with a return to fish oil in turbot (Psetta maxima). Aquaculture, 217(1-4), 465-482. doi:10.1016/s0044-8486(02)00259-4Bell, J. G., McEvoy, J., Tocher, D. R., McGhee, F., Campbell, P. J., & Sargent, J. R. (2001). Replacement of Fish Oil with Rapeseed Oil in Diets of Atlantic Salmon (Salmo salar) Affects Tissue Lipid Compositions and Hepatocyte Fatty Acid Metabolism. The Journal of Nutrition, 131(5), 1535-1543. doi:10.1093/jn/131.5.1535Bell, J. G., & Sargent, J. R. (2003). Arachidonic acid in aquaculture feeds: current status and future opportunities. Aquaculture, 218(1-4), 491-499. doi:10.1016/s0044-8486(02)00370-8Torstensen, B. E., Froyland, L., & Lie, O. (2004). Replacing dietary fish oil with increasing levels of rapeseed oil and olive oil - effects on Atlantic salmon (Salmo salar L.) tissue and lipoprotein lipid composition and lipogenic enzyme activities. Aquaculture Nutrition, 10(3), 175-192. doi:10.1111/j.1365-2095.2004.00289.xSaito, H. (2012). Lipid characteristics of two subtropical Seriola fishes, Seriola dumerili and Seriola rivoliana, with differences between cultured and wild varieties. Food Chemistry, 135(3), 1718-1729. doi:10.1016/j.foodchem.2012.05.122Rodríguez-Barreto, D., Jerez, S., Cejas, J. R., Martin, M. V., Acosta, N. G., Bolaños, A., & Lorenzo, A. (2015). Effect of different rearing conditions on body lipid composition of greater amberjack broodstock (Seriola dumerili ). Aquaculture Research, 48(2), 505-520. doi:10.1111/are.12898Rodríguez-Barreto, D., Jerez, S., Cejas, J. R., Martin, M. V., Acosta, N. G., Bolaños, A., & Lorenzo, A. (2014). Ovary and egg fatty acid composition of greater amberjack broodstock (Seriola dumerili) fed different dietary fatty acids profiles. European Journal of Lipid Science and Technology, 116(5), 584-595. doi:10.1002/ejlt.201300462O’Neill, B., Le Roux, A., & Hoffman, L. C. (2015). Comparative study of the nutritional composition of wild versus farmed yellowtail (Seriola lalandi). Aquaculture, 448, 169-175. doi:10.1016/j.aquaculture.2015.05.034Rombenso, A. N., Trushenski, J. T., & Drawbridge, M. (2018). Saturated lipids are more effective than others in juvenile California yellowtail feeds—Understanding and harnessing LC-PUFA sparing for fish oil replacement. Aquaculture, 493, 192-203. doi:10.1016/j.aquaculture.2018.04.040SENO-O, A., TAKAKUWA, F., HASHIGUCHI, T., MORIOKA, K., MASUMOTO, T., & FUKADA, H. (2008). Replacement of dietary fish oil with olive oil in young yellowtailSeriola quinqueradiata: effects on growth, muscular fatty acid composition and prevention of dark muscle discoloration during refrigerated storage. Fisheries Science, 74(6), 1297-1306. doi:10.1111/j.1444-2906.2008.01655.xFukada, H., Taniguchi, E., Morioka, K., & Masumoto, T. (2017). Effects of replacing fish oil with canola oil on the growth performance, fatty acid composition and metabolic enzyme activity of juvenile yellowtail Seriola quinqueradiata (Temminck & Schlegel, 1845). Aquaculture Research, 48(12), 5928-5939. doi:10.1111/are.13416Bergman, A. M., Trushenski, J. T., & Drawbridge, M. (2018). Replacing Fish Oil with Hydrogenated Soybean Oils in Feeds for Yellowtail. North American Journal of Aquaculture, 80(2), 141-152. doi:10.1002/naaq.10015Stuart, K., Johnson, R., Armbruster, L., & Drawbridge, M. (2018). Arachidonic Acid in the Diet of Captive Yellowtail and Its Effects on Egg Quality. North American Journal of Aquaculture, 80(1), 97-106. doi:10.1002/naaq.10003Bell, J. G., McGhee, F., Campbell, P. J., & Sargent, J. R. (2003). Rapeseed oil as an alternative to marine fish oil in diets of post-smolt Atlantic salmon (Salmo salar): changes in flesh fatty acid composition and effectiveness of subsequent fish oil «wash out». Aquaculture, 218(1-4), 515-528. doi:10.1016/s0044-8486(02)00462-3STUBHAUG, I., LIE, Ø., & TORSTENSEN, B. E. (2007). Fatty acid productive value and ?-oxidation capacity in Atlantic salmon (Salmo salar L.) fed on different lipid sources along the whole growth period. Aquaculture Nutrition, 13(2), 145-155. doi:10.1111/j.1365-2095.2007.00462.xIkemoto, A., Nitta, A., Furukawa, S., Ohishi, M., Nakamura, A., Fujii, Y., & Okuyama, H. (2000). Dietary n-3 fatty acid deficiency decreases nerve growth factor content in rat hippocampus. Neuroscience Letters, 285(2), 99-102. doi:10.1016/s0304-3940(00)01035-1Kitajka, K., Puskas, L. G., Zvara, A., Hackler, L., Barcelo-Coblijn, G., Yeo, Y. K., & Farkas, T. (2002). The role of n-3 polyunsaturated fatty acids in brain: Modulation of rat brain gene expression by dietary n-3 fatty acids. Proceedings of the National Academy of Sciences, 99(5), 2619-2624. doi:10.1073/pnas.042698699Kreps, E. ., Chebotarëva, M. ., & Akulin, V. . (1969). Fatty acid composition of brain and body phospholipids of the anadromous salmon, Oncorhynchus nerka, From fresh-water and marine habitat. Comparative Biochemistry and Physiology, 31(3), 419-430. doi:10.1016/0010-406x(69)90023-1Caballero, M. ., Obach, A., Rosenlund, G., Montero, D., Gisvold, M., & Izquierdo, M. . (2002). Impact of different dietary lipid sources on growth, lipid digestibility, tissue fatty acid composition and histology of rainbow trout, Oncorhynchus mykiss. Aquaculture, 214(1-4), 253-271. doi:10.1016/s0044-8486(01)00852-3Campos, I., Matos, E., Maia, M. R. G., Marques, A., & Valente, L. M. P. (2019). Partial and total replacement of fish oil by poultry fat in diets for European seabass (Dicentrarchus labrax) juveniles: Effects on nutrient utilization, growth performance, tissue composition and lipid metabolism. Aquaculture, 502, 107-120. doi:10.1016/j.aquaculture.2018.12.004Pagliarani, A., Pirini, M., Trigari, G., & Ventrella, V. (1986). Effect of diets containing different oils on brain fatty acid composition in sea bass (Dicentrarchus labrax L.). Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 83(2), 277-282. doi:10.1016/0305-0491(86)90366-4Skalli, A., Robin, J. H., Le Bayon, N., Le Delliou, H., & Person-Le Ruyet, J. (2006). Impact of essential fatty acid deficiency and temperature on tissues’ fatty acid composition of European sea bass (Dicentrarchus labrax). Aquaculture, 255(1-4), 223-232. doi:10.1016/j.aquaculture.2005.12.00

Production of a Symbiotic Biopreparation (Mixture of Agave fourcroydes Lem. Pulp and PROBIOLACTIL®) for Use in Calves

Context: Artificial calf breeding may lead to gastric disorders in animals, which are produced due to inappropriate nutritional practices. Objective: Production of a Symbiotic Biopreparate (Mixture of Agave fourcroydes Lem. Pulp and PROBIOLACTIL®) in Calves. Methods: The design and optimization of this biopreparation was based on the response surface method, with a rotating central composite experimental design 22, and two replications. Henequen pulp was used with the addition of molasses and yeast hydrolyzate, as sources of sugar and nitrogen, respectively, and PROBIOLACTIL® for supplementation of Lactobacillus salivarius. The experiment lasted 28 days, with a completely randomized design, to evaluate the effect of this additive on the productive and health indicators of Mambi de Cuba calves, at weaning and breeding. Results: Optimum values were achieved for the components of the biopreparation, which increased the production of Lactobacillus. The application of the additive improved live weight, mean daily gain, and weight gain, from the 21st day on, and its influence on health was seen through a reduction in the occurrence of diarrhea. Conclusions: The biopreparation was designed from a probiotic culture of agroindustrial residues, then enriched with highly available national components. This symbiotic biopreparation may be used as a nutritional additive in weaned calves

Hemophagocytic syndrome. Case report and review of the disease

El síndrome hemofagocítico fue descrito por primera vez, en 1939, como una condición febril acompañada de adenomegalias, citopenias y proliferación histiocítica en la médula ósea; su incidencia es baja, se estima en uno o dos casos/millón de individuos/año, pero muy probablemente, ha sido subestimada, pues en muchas ocasiones es un diagnóstico que no se sospecha. En este artículo se presenta una paciente con un síndrome hemofagocítico reactivo idiopático diagnosticado en la Sala de Medicina D, del Servicio de Medicina Interna del Hospital “Arnaldo Milián Castro”, en la que no se demostró asociación con inmunodepresión, drogas u otro proceso infeccioso, autoinmune o neoplásico. El objetivo de este trabajo, además de comunicar este caso, es resaltar la importancia del diagnóstico precoz de este padecimiento y de las graves alteraciones que le acompañan, responsables de una alta mortalidad, además de realizar una revisión de las manifestaciones clínicas, la patología y el diagnóstico y el tratamiento de estos pacientes.The hemophagocytic syndrome was described for the first time, in 1939, as a febrile condition accompanied by adenomegaly, cytopenias and histiocytic proliferation in the bone marrow; Its incidence is low, it is estimated in one or two cases/million of individuals/year, but most probably, it has been underestimated, on many occasions it is a diagnosis that is not suspected. In this article, it is presented a female patient with an idiopathic reactive hemophagocytic syndrome diagnosed in the Medicine Room D of the Internal Medicine Service of “Arnaldo Milián Castro” Hospital, in which there was no association with immunosuppression, drugs or other infectious process, autoimmune or neoplastic. The aim of this study, besides communicate this case, is to emphasize the importance of the early diagnosis of this disease and the serious alterations that accompany it, responsible for a high mortality rate, as well as a review of the clinical manifestations, pathology and diagnosis and treatment of these patients