Las transformaciones de la cultura áulica: la corte de la Monarquía Católica como corte del Barroco

La Corte no fue solamente el “lugar” donde estaba el rey, sino una organización política-social, emanada del feudalismo, que englobaba todo el Reino. Esta organización política tenía sus fundamentos en los principios de la filosofía práctica clásica (Aristóteles) y creó su propia cultura (cultura cortesana). Ahora bien, los valores en los que se basaba, cambiaron paulatinamente a lo largo del tiempo: del cortesano humanista del siglo XVI se pasó al cortesano discreto del siglo XVII. La Monarquía hispana también experimentó una profunda transformación entre ambos siglos, lo que permitió que el cortesano del barroco se transformara en el modelo católico.The court was not only the “place” where the king was, but a social-political organisation, which emanated from feudalism and encompassed the whole kingdom. This political organisation was based on the principles of classical practical philosophy (Aristotle) and created its own culture (court culture). However, the values on which it was based changed gradually over time: from the humanist courtier of the 16th century to the discreet courtier of the 17th century. The Hispanic Monarchy also underwent a profound transformation between the two centuries, which allowed the baroque courtier to be transformed into the Catholic model

Nuevos copolímeros a base de indol

Referencia OEPM: 9300155.-- Fecha de solicitud: 28/01/1993.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).Nuevos copolímeros a base de indol (ver figura en archivo de texto adjunto). La presente invención se refiere a un nuevo tipo de copolímeros de base indol de fórmula general (I), en la que R puede ser los heterociclos tiofeno y pirrol, DP son restos del agente oxidante que actúa como agente dopante. Para la obtención de los copolímeros se hace reaccionar indol con los heterociclos tiofeno o pirrol preferentemente a temperatura entre 25-30ºC en presencia de agente oxidante tal como el cloruro férrico, disueltos en cloroformo. En ambos casos se utilizan distintas relaciones molares de oxidante/monómero entre 1.5 y 5 y de comonómero/indol entre 1.5 y 9. Al final de la reacción se precipita el copolímero con una mezcla metanol/agua (1:1 en peso). Estos polímeros se caracterizan por presentar una marcada conductividad eléctrica y ser fácilmente solubles, lo que les hace ser aptos para diversas aplicaciones como conductores.Peer reviewe

Materialities, Space, Mind: Archaeology of Visual Cognition

A perceptual study of different styles of prehistoric Galician ceramics (from 6000 to 2000 BP) conducted by eye-tracking, underpins the material engagement of mind by showing that the visual world fosters the entanglement between doing, seeing, and designing through history. This text examines how materializations of human practices relate to cognition and to socio-cultural contexts. By combining evidence on the relationship between material culture and perceptual reactions, our text aims to understand the entanglement between the mind, objects and the world. We apply measurable and numeric techniques, providing an archaeometric approach to cognitive topics by combining neurosciences with interpretive and reflective research. This research provides new insights into the material culture, contributes to the understanding of the relationship between mind and the material world, and accounts for the transitive engagement between the way of thinking, seeing and making things. Thus, the text contributes to an understanding of the material forces driving perception and thought

Extending Graph (Discrete) Derivative Descriptors to N-Tuple Atom-Relations

In the present manuscript, an extension of the previously defined Graph Derivative Indices (GDIs) is discussed. To achieve this objective, the concept of a hypermatrix, conceived from the calculation of the frequencies of triple and quadruple atom relations in a set of connected sub-graphs, is introduced. This set of subgraphs is generated following a predefined criterion, known as the event (S), being in this particular case the connectivity among atoms. The triple and quadruple relations frequency matrices serve as a basis for the computation of triple and quadruple discrete derivative indices, respectively. The GDIs are implemented in a computational program denominated DIVATI (acronym for DIscrete DeriVAtive Type Indices), a module of TOMOCOMD-CARDD program. Shannon‟s entropy-based variability analysis demonstrates that the GDIs show major variability than others indices used in QSAR/QSPR researches. In addition, it can be appreciated when the indices are extended over n-elements from the graph, its quality increases, principally when they are used in a combined way. QSPR modeling of the physicochemical properties Log P and Log K of the 2-furylethylenes derivatives reveals that the GDIs obtained using the tripleand quadruple matrix approaches yield superior performance to the duplex matrix approach. Moreover, the statistical parameters for models obtained with the GDI method are superior to those reported in the literature by using other methods. It can therefore be suggested that the GDI method, seem to be a promissory tool to reckon on in QSAR/QSPR studies, virtual screening of compound datasets and similarity/dissimilarity evaluations

Identificación inicial de genes en Babesia bigemina mediante análisis de Etiquetas de Secuencia Expresadas en el estadio intraeritrocítico del parásito

In this study, Expressed Sequence Tags (EST) were obtained and analyzed from 2208 randomly selected clones containing plasmids with cDNA inserts derived from a Babesia bigemina library. The obtained sequences were extracted and subject to Blast homology search in the Genbank databases. Sequence homology analysis resulted in the identification of 470 clones (grouped in 267 distinct clusters) which contained EST with no significant sequence identity with Babesia sp genes or other Apicomplexan parasites. Presumably, these EST would correspond either to new, unreported B. bigemina transcribed genes present in the erythrocyte stages of the parasite, or to non-translated sequences of the putative genes. 21 clones were identified which contained EST corresponding to 6 genes coding for B. bigemina antigens already reported in the literature; 1285 clones (grouped in 159 clusters of distinct sequences) had significant sequence identity with genes coding for hypothetical proteins previously identified in the Babesia bovis genome. Moreover, 32 clones had EST corresponding to 16 different Theileria sp. genes; 51 clones (26 distinct sequences) showed EST with sequence similarity to genes of Plasmodium sp., 25 EST had low identity with 13 different Toxoplasma gondii genes; and 4 clones with EST for 4 different Cryptosporidium sp genes. The results obtained, in addition to EST analysis of a larger number of B. bigemina cDNA clones, will allow the characterization and, eventually, the manipulation of gene coding regions, essential for the establishment of improved control strategies for cattle babesiosis caused by B. bigemina.En este estudio se realizó el análisis de Etiquetas de Secuencias Expresadas (EST) obtenidas a partir de 2208 clonas de Escherichia coli, con plásmidos recombinantes conteniendo insertos de cDNA de Babesia bigemina. Las secuencias se analizaron mediante búsqueda de homología en las bases de datos de genes. El análisis de homología en secuencia permitió identificar 470 clonas (agrupadas en 267 clusters) conteniendo EST con similitud de secuencia estadísticamente no significativa con algún gen de Babesia spp o de otro organismo Apicomplexa, sugiriendo la presencia de genes nuevos de B. bigemina; Se identificaron 21 clonas con EST correspondientes a 6 secuencias de genes previamente reportados para B. bigemina; además de 1285 clonas (conformando 159 clusters de genes distintos) de identidad significativa con proteínas hipotéticas o correspondientes a genes ya reportados en el genoma secuenciado de Babesia bovis; 32 clonas con EST homólogas a 16 genes distintos de Theileria spp; 51 clonas (26 genes distintos) con similitud en secuencia a genes de Plasmodium spp; 25 clonas con EST de moderada similitud con 13 genes distintos genes de Toxoplasma gondii; y 4 clonas con EST de mayor identidad con 4 genes diferentes de Cryptosporidium spp. Los resultados obtenidos permiten elaborar una base de datos sobre EST del estadio intraeritrocítico de Babesia bigemina, información básica esencial para la caracterización molecular del parásito, que permite llevar a cabo la identificación y regulación de nuevas regiones génicas codificadoras y, eventualmente el establecimiento de nuevas estrategias de control de la babesiosis bovina causada por B. bigemina

Development of FEM/BEM and SEA models from experimental results for structural elements with attached equipment

This work focuses on the analysis of a structural element of MetOP-A satellite. Given the special interest in the influence of equipment installed on structural elements, the paper studies one of the lateral faces on which the Advanced SCATterometer (ASCAT) is installed. The work is oriented towards the modal characterization of the specimen, describing the experimental set-up and the application of results to the development of a Finite Element Method (FEM) model to study the vibro-acoustic response. For the high frequency range, characterized by a high modal density, a Statistical Energy Analysis (SEA) model is considered, and the FEM model is used when modal density is low. The methodology for developing the SEA model and a compound FEM and Boundary Element Method (BEM) model to provide continuity in the medium frequency range is presented, as well as the necessary updating, characterization and coupling between models required to achieve numerical models that match experimental results

Reduced membrane-bound alkaline phosphatase does not affect binding of Vip3Aa in a Heliothis virescens resistant colony

The Vip3Aa insecticidal protein from Bacillus thuringiensis (Bt) is produced by specific transgenic corn and cotton varieties for efficient control of target lepidopteran pests. The main threat to this technology is the evolution of resistance in targeted insect pests and understanding the mechanistic basis of resistance is crucial to deploy the most appropriate strategies for resistance management. In this work, we tested whether alteration of membrane receptors in the insect midgut might explain the >2000-fold Vip3Aa resistance phenotype in a laboratory-selected colony of Heliothis virescens (Vip-Sel). Binding of 125I-labeled Vip3Aa to brush border membrane vesicles (BBMV) from 3rd instar larvae from Vip-Sel was not significantly different from binding in the reference susceptible colony. Interestingly, BBMV from Vip-Sel larvae showed dramatically reduced levels of membrane-bound alkaline phosphatase (mALP) activity, which was further confirmed by a strong downregulation of the membrane-bound alkaline phosphatase 1 (HvmALP1) gene. However, the involvement of HvmALP1 as a receptor for the Vip3Aa protein was not supported by results from ligand blotting and viability assays with insect cells expressing HvmALP1

Determinación espectrofluorométrica en frutas de Ca(II) al estado de Ca-Calceína

Se ha propuesto un método espectrofluorométrico para la determinación de Ca(II) en frutas previa formación del quelato Ca-Calceina. Los resultados obtenidos son reproducibles y el método es más selectivo que otros métodos espectrofotométricos. La determinación de Ca(II) es posible directamente y en tiempo menor que el empleado con otros métodos espectrofotométricos.A spectrofluorometric method is proposed for determination of Ca (ID in fruits based on the Ca-Caloceine chelate. The resultats obtained are perfectly reproducible and the method becomes more selective than other spectrofotometl'ic methods. The determination of Ca (ID is directly possible in less time than other spectrofotometric methods

Materialidades, espacio, pensamiento: arqueología de la cognición visual

This article presents a perceptual study of different styles of prehistoric Galician ceramics (from 6000 to 2000 BP) using the technique of eye-tracking. This analysis demonstrates the material engagement of mind by showing that the visual world fosters the entanglement of doing, seeing, and designing over the course of history. We examine how materializations of human practices relate to cognition and to socio-cultural contexts. The interrelations between material culture and perceptual reactions indicate a clear connection between the mind, objects and the world. We apply measurable and numeric techniques, providing an archaeometric approach to cognitive topics by combining neurosciences with interpretive and reflective research. This research provides new insights into the material culture, contributes to the understanding of the relationship between mind and the material world, and accounts for the transitive engagement between ways of thinking, seeing and making things. Thus the text contributes to understand the material forces driving perception and thought.En el presente artículo se realiza un estudio perceptual de diferentes estilos de cerámica prehistórica de Galicia (con cronología entre el 6000 y el 2000 BP) mediante la técnica de seguimiento de movimientos oculares. Este análisis permite comprobar la relación de la mente con la materialidad y sugiere la existencia de una estrecha imbricación entre el diseñar, el ver y el hacer a lo largo de la historia. El trabajo examina cómo las materializaciones de las prácticas humanas se correlacionan con la cognición y con el contexto socio-cultural. Las interrelaciones de la cultura material y el comportamiento perceptual, apuntan a una clara conexión entre la mente, los objetos y el mundo. El trabajo aplica técnicas medibles y numéricas, que permiten hacer una aproximación arqueométrica a temas cognitivos mediante la combinación de las neurociencias con investigación interpretativa y reflexiva. Esta investigación ofrece nuevas perspectivas sobre la cultura material y contribuye a comprender la interrelación entre la mente y el mundo material, así como la existencia de un vínculo transitivo entre formas de pensar, de mirar y de hacer cosas. De este modo, el texto hace algunos aportes para entender las fuerzas materiales que guían la percepción y el pensamiento