Editorial

La Revista Psicoespacios es una publicación de la Facultad de Ciencias Sociales de la Institución Universitaria de Envigado. Fue creada en el año 2005, y la cual a partir del presente año tendrá una edición semestral en su publicación, esto con el propósito de difundir los trabajos académicos, tanto de docentes como de estudiantes dedicados al campo de la psicología y discursos afines

El modelo instruccional ADDIE en el aprendizaje de la cinemática, institución educativa nivel secundario de EBR distrito Mariano Melgar, Arequipa 2021

El presente trabajo de investigación tiene como objetivo determinar la influencia del Modelo Instruccional ADDIE en el aprendizaje de la cinemática en el quinto grado de EBR nivel secundaria, en la Institución Educativa G.U.E Mariano Melgar Valdivieso del distrito de Mariano Melgar en el año 2021, el cual se realiza mediante el enfoque cuantitativo, de tipo experimental y de diseño pre- experimental, la muestra está conformada por 15 estudiantes de una población de 203 estudiantes, pertenecientes a la institución educativa GUE Mariano Melgar Valdivieso de Arequipa, es necesario mencionar que por conveniencia la muestra es no probabilística y que la variable “ aprendizaje de la cinemática” va a ser medida mediante un cuestionario en 2 momentos: Pre Test y Post Test. Los resultados son favorables, influyendo positivamente el Modelo ADDIE en el aprendizaje de la cinemática, existiendo una mejora en el rendimiento académico de los estudiantes, esto es corroborado mediante la prueba estadística no paramétrica llamada Wilcoxon

Efecto del ozono gaseoso sobre las características fisicoquímicas, microbiologicas y apariencia general de Punica Granatum L. wonderful fresca

Evaluate the effect of gaseous ozone on physicochemical characteristics, molds and yeasts count and overall appearance of granada. Wonderful variety fruits of granada was collected in a glass chamber where the gas is injected using ozone generator equipment with flow of 500 mg / h and a digital meter for measuring the ozone concentration. A central composite design rotable (CCDR) was used to analyze the effect of the concentration of ozone gas and storage time (p < 0.05) on weight loss, firmness, shell color, soluble solids, mold and yeasts count, total anthocyanins content and overall appearance. It was determined that the concentration of ozone gas had significant effect on the responses studied variables. The quadratic model provided the best fit of data. It was established that the concentration of ozone between 40 - 50 ppm, it allows for the lowest weight loss, low count of molds and yeasts; greater firmness, soluble solids, shell color, total anthocyanins content and overall appearance in Granada during 50 - 55 days of storage.El objetivo del presente estudio fue evaluar el efecto del ozono gaseoso sobre las características fisicoquímicas, recuento mohos y levaduras y apariencia general de granada. Se trabajó con frutos de granada variedad Wonderful acopiados en una cámara de vidrio donde se inyectó el gas utilizando un equipo generador de ozono con flujo de 500 mg / h, y un medidor digital para cuantificar la concentración de ozono. Se utilizó un diseño compuesto central rotable (DCCR) para analizar el efecto de la concentración de ozono gaseoso y tiempo de almacenamiento (p < 0,05) sobre la pérdida de peso, firmeza, color en cáscara, sólidos solubles, recuento mohos y levaduras, contenido de antocianinas totales y apariencia general. Se determinó que la concentración de ozono gaseoso tuvo efecto significativo en las variables respuestas estudiadas. El modelo cuadrático presentó el mejor ajuste de datos. Se estableció que la concentración de ozono entre 40 - 50 ppm permitió obtener la menor pérdida de peso, bajo recuento de mohos y levaduras; mayor firmeza, contenido de sólidos solubles, color en cáscara, contenido de antocianinas totales y apariencia general en granada durante 50 – 55 días de almacenamiento

An invertebrate smooth muscle with striated muscle myosin filaments

Muscle tissues are classically divided into two major types, depending on the presence or absence of striations. In striated muscles, the actin filaments are anchored at Z-lines and the myosin and actin filaments are in register, whereas in smooth muscles, the actin filaments are attached to dense bodies and the myosin and actin filaments are out of register. The structure of the filaments in smooth muscles is also different from that in striated muscles. Here we have studied the structure of myosin filaments from the smooth muscles of the human parasite Schistosoma mansoni. We find, surprisingly, that they are indistinguishable from those in an arthropod striated muscle. This structural similarity is supported by sequence comparison between the schistosome myosin II heavy chain and known striated muscle myosins. In contrast, the actin filaments of schistosomes are similar to those of smooth muscles, lacking troponin-dependent regulation. We conclude that schistosome muscles are hybrids, containing striated muscle-like myosin filaments and smooth muscle-like actin filaments in a smooth muscle architecture. This surprising finding has broad significance for understanding how muscles are built and how they evolved, and challenges the paradigm that smooth and striated muscles always have distinctly different components

Asignación multicanal usando K-Means en redes de radio cognitiva

Context: The developed scheme allows carrying out the assignment of several frequency channels (both contiguous and not contiguous) available to the secondary users that require a higher bandwidth, under an environment of equality.Objective: The following paper develops a multichannel assignment which allows taking in a more efficient way the spectral opportunities in cognitive radio networks.Method: The developed assignment model is composed by the K-Means algorithm, which is in charged of carrying out the grouping of channels through clusters for the best parameters, and another algorithm in charge of establishing an equal criteria for all the secondary users that wish to transmit. The reached results were evaluated with experimental spectral occupancy data taken from the GSM frequency band. The developed model was compared with the MFA-CRN algorithm.Results: The obtained measurements correspond to the average bandwidth, the average delay, and the fairness calculation in the assignment of several channels. The developed assignment model shows an improvement in the assignment of a higher transmission average bandwidth for each secondary user while maintaining the fairness criteria in the channel assignments.Conclusion: Despite the increasing in the number of handoffs, it is also observed that metrics such as average bandwidth, average throughput and average delay are never negatively impacted by this increase in handoffs.Contexto: El esquema desarrollado permite realizar la asignación de varios canales de frecuencia tanto contiguos como no contiguos que se encuentren disponibles a usuarios secundarios que requieran un mayor ancho de banda, bajo un ambiente de equidad.Objetivo: El presente trabajo desarrolla un modelo de asignación múltiple de canales que permite aprovechar de forma más eficiente las oportunidades espectrales en redes de radio cognitiva.Método: El modelo de asignación desarrollado está compuesto por el algoritmo K-Means, encargado de realizar el agrupamiento de canales mediante clústeres para los mejores parámetros y otro encargado de establecer un criterio de equidad para todos los usuarios secundarios que deseen transmitir. Los resultados alcanzados se evaluaron con datos experimentales de ocupación espectral, capturados en la banda de frecuencia GSM. El modelo desarrollado fue comparado con el algoritmo MFA-CRN.Resultados: Las mediciones realizadas corresponden al ancho de banda promedio, el retardo promedio y el cálculo de fairness en la asignación de varios canales. El modelo desarrollado evidencia una mejora en la asignación de un mayor ancho de banda promedio de trasmisión para cada usuario secundario, manteniendo el criterio de equidad en la asignación de los canales.Conclusión: A pesar del aumento en el número de handoffs, se observa que métricas como ancho de banda promedio, throughput promedio y retardo promedio no se ven en ningún momento impactadas de manera negativa frente a este aumento de handoffs

The molecular and phenotypic spectrum of CLCN4-related epilepsy

Objective This study was undertaken to expand the phenotypic and genetic spectrum of CLCN4-related epilepsy and to investigate genotype–phenotype correlations. Methods We systematically reviewed the phenotypic and genetic spectrum of newly diagnosed and previously reported patients with CLCN4-related epilepsy. Three novel variants identified in four patients reported in this study were evaluated through in silico prediction and functional analysis by Western blot, immunofluorescence, and electrophysiological measurements. Results Epilepsy was diagnosed in 54.55% (24/44) of individuals with CLCN4-related disorders and was drug-resistant in most cases. Of 24 patients, 15 had epileptic encephalopathy and four died at an early age; 69.57% of patients had seizure onset within the first year of life. Myoclonic seizures are the most common seizure type, and 56.25% of patients presented multiple seizure types. Notably, seizure outcome was favorable in individuals with only one seizure type. All patients showed intellectual disability, which was severe in 65.22% of patients. Additional common features included language delay, behavioral disorders, and dysmorphic features. Five patients benefitted from treatment with lamotrigine. Most variants, which were mainly missense (79.17%), were inherited (70.83%). Whereas frameshift, intragenic deletion, or inherited variants were associated with milder phenotypes, missense or de novo variants led to more severe phenotypes. All evaluated CLCN4 variants resulted in loss of function with reduced ClC-4 currents. Nonetheless, genotype–phenotype relationships for CLCN4-related epilepsy are not straightforward, as phenotypic variability was observed in recurrent variants and within single families. Significance Pathogenic CLCN4 variants contribute significantly to the genetic etiology of epilepsy. The phenotypic spectrum of CLCN4-related epilepsy includes drug-resistant seizures, cognitive and language impairment, behavioral disorders, and congenital anomalies. Notably, the mutation type and the number of seizure types correlate with the severity of the phenotype, suggesting its use for clinical prognosis. Lamotrigine can be considered a therapeutic option

TRACKING LEAD (Pb) IN THE ENVIRONMENT OF JAKARA, KANO STATE, NIGERIA

Lead is considered a toxic substance that is already available in environment and has health impacts. The objective of the present study is to track the availability of lead in the environment of Jakara, Kano State, Nigeria. Lead was tracked in water, soil, and vegetables including lettuce, spinach, and onion. Study methodology involved taking random samples from water, soil, and vegetables at Jakara. Samples were prepared and assayed by atomic absorption spectrometry. Study findings showed that the mean concentration of lead in water was 0.115±0.023 mg/l, while it was in soil 2.46 ±0.95 μg/g. The mean concentration of lead in both lettuce and spinach was the same (22.95+ 3.28 mg/kg), and in onion was 19.67 ±3.28 mg/kg . Conclusions: the present study showed that there is a lead contamination of Jakara region by heavy metal (lead). This contamination is evident in water, soil, and vegetables