Desenvolvimento de competências criativas: um estudo com alunos angolanos do ensino primário

Desenvolver a criatividade dos alunos e a relação desta com a aprendizagem é uma preocupação atual. Este trabalho pretendeu estudar o impacto do programa SuperCriativo (Oliveira, 2015) em competências criativas, no clima criativo em sala de aula e no sucesso académico (particularmente em dimensões de expressão oral e escrita). Os participantes foram 70 alunos da 4º classe em Angola, correspondendo 35 ao grupo experimental e 35 ao grupo controlo. Num pré e pós teste, a criatividade foi avaliada por um produto criativo (um texto), uma Escala (Morais, Viana, Dias, Fleith & Alencar, 2019), validada em Portugal. Foi ainda avaliado o clima criativo em sala de aula, assim como o sucesso escolar através da média global e das classificações a Português . Os resultados indicaram melhorias estatisticamente significativas no grupo experimental nas diferentes variáveis. Estes ganhos podem ser um estímulo à promoção da criatividade na sala de aula, não só em Angola, mas em outros países. Implicações futuras são discutidas.Developing the studentŽs creativity and researching the relationship between creativity and shoolar achievement are actual concerns. Ths study wanted to research the impact of the "Supercreative" Program (Oliveira, 2015) in creative skills, in the classroom creative climate and in the academic achievement (mainly in oral and written expression). Participants were 70 students of 4th year of Angola schooling, corresponding 35 to the experimental group and 35 to the control group. There were pre and post test moments, being evaluated, in both, creativity, through a creative product (a text), the creative climate in classroom, through a scale validated to Portugal (Morais, Viana, Dias, Fleith & Alencar, 2019) and the academic achievement through an average score and the Portuguese language score. Results showed improvements statistically significant in the experimental group in all the variables. These improvements can be a stimulus to the promotion of creativity in the classroom, not only in Angola but also in other countries. Future implications of results are discussed

Promotion of creative skills: a study with primary students of Angola

Desenvolver a criatividade dos alunos e a relação desta com a aprendizagem é uma preocupação atual. Este trabalho pretendeu estudar o impacto do programa SuperCriativo (Oliveira, 2015) em competências criativas, no clima criativo em sala de aula e no sucesso académico (particularmente em dimensões de expressão oral e escrita). Os participantes foram 70 alunos da 4º classe em Angola, correspondendo 35 ao grupo experimental e 35 ao grupo controlo. Num pré e pós teste, a criatividade foi avaliada por um produto criativo (um texto), uma Escala (Morais, Viana, Dias, Fleith & Alencar, 2019), validada em Portugal. Foi ainda avaliado o clima criativo em sala de aula, assim como o sucesso escolar através da média global e das classificações a Português . Os resultados indicaram melhorias estatisticamente significativas no grupo experimental nas diferentes variáveis. Estes ganhos podem ser um estímulo à promoção da criatividade na sala de aula, não só em Angola, mas em outros países. Implicações futuras são discutidasDeveloping the student´s creativity and researching the relationship between creativity and shoolar achievement are actual concerns. Ths study wanted to research the impact of the “Supercreative” Program (Oliveira, 2015) in creative skills, in the classroom creative climate and in the academic achievement (mainly in oral and written expression). Participants were 70 students of 4th year of Angola schooling, corresponding 35 to the experimental group and 35 to the control group. There were pre and post test moments, being evaluated, in both, creativity, through a creative product (a text), the creative climate in classroom, through a scale validated to Portugal (Morais, Viana, Dias, Fleith & Alencar, 2019) and the academic achievement through an average score and the Portuguese language score. Results showed improvements statistically significant in the experimental group in all the variables. These improvements can be a stimulus to the promotion of creativity in the classroom, not only in Angola but also in other countries. Future implications of results are discussed

West Nile Fever Virus Infection in Horses in São Paulo State, Brazil

Background: The West Nile virus (WNV) antibodies were reported in Brazil in the serum samples taken from horses and birds in the Midwest region and Paraíba state in 2008 and 2013, respectively. In 2014, the first human case was confirmed in a rural worker in the state of Piauí and, in 2018, the virus was isolated from the central nervous system of a horse with nervous symptoms in the state of Espírito Santo. The virus is a member of the Flaviviridae family of the genus Flavivirus (neurotropic), infecting several mammalian species, with humans and horses being the most susceptible. Approximately 35% of horses develop clinical signs, thus they are considered the best sentinels for this disease. The aim of this case report is to describe the first confirmed cases of West Nile Fever (WNF) in two horses in the state of São Paulo.Cases: Two horses with neurological symptoms were treated at the Veterinary Hospital of Cruzeiro do Sul University (São Paulo, SP), in 2019. Both horses came from neighboring regions that have a large Atlantic Forest preservation area and are also routes for migratory birds, known to be competent hosts for transmitting the West Nile Fever virus, such as the swallow, the falcon and the hawk. The first one had symptoms, such as weakness and sporadic seizures; however, after recovering, it was hospitalized a few days later due to kidney failure and laminitis. The second one showed incoordination, pelvic limb weakness, and was walking in circles, evolving to seizures. Both animals were euthanized, and their central nervous system samples and total blood samples were tested for rabies, herpes virus, and WNV; the first 2 tests showed negative results. Ribonucleic acids (RNA) were extracted from erythrocytes using the polymerase chain reaction (PCR) technique in-house. The WNV-specific reverse transcription-polymerase chain reaction amplification products were obtained using the nested PCR-multiplex PCR combination.Discussion: Since the 1940s, several WNF outbreaks have been reported around the world (Africa, Europe, Asia and Middle East). In the 2000s, the USA had the most amount of WNF cases reported; cases started being reported in Central and South America in the following years. The virus was identified for the first time in Brazil in 2014. Since then, our country is a route for migratory birds, with many states still having forests, several arboviruses are found such as WNF, which could become a public health problem. Both horses in the present study showed neurological signs and the horse that recovered had renal failure. Such signs are inconclusive, however, similar to those that occur in humans infected by the virus in its neurotropic form. The emergence of new diseases is an important aspect of public health. The literature is vast regarding the description of the pathogenesis, clinical signs, diagnosis, viral persistence and sequelae of WNF in humans, however, it is scarce regarding the viral persistence and sequelae of the disease in horses. Future studies are needed to understand the post-infection period in horses, as they are the most sensitive animals along with humans to this virus. Here, we report the first confirmed cases of WNF in the city of São Paulo to bring awareness about considering this disease while diagnosing horses with nervous system disorders.Keywords: encephalitis, horses, flavivirus, mosquito.Título: Infecção pelo vírus da Febre do Nilo Ocidental em equinos no Estado de São PauloDescritores: encefalite, equinos, flavivírus, mosquito

Systematization of nursing care to children and adolescents in psychological distress

Objective: to list the main diagnoses, nursing interventions and results described by NANDA International (NANDA-I), Nursing Outcomes Classification (NOC), Nursing Intervention Classification (NIC) for children and adolescents in psychological distress, based on the theory of mental health recovery - Mare de Baker Theory. Method: a descriptive exploratory study with qualitative approach carried out in CAPSi of the Executive Secretary of the Regional IV (SER IV), in Fortaleza-CE. For data analysis, the structure of the collected data and the diagnostic reasoning were used. Results: initially, 28 nursing diagnoses were pre-selected, prevailing only six. Conclusion: with the implementation of systematization of nursing care (SNC), nurses have a unique and different way, seeking to promote reintegration of these people with mental disorders in their own family and society

Astrocytic expression of GFAP and serum levels of IL-1β and TNF-α in rats treated with different pain relievers

Pro-inflammatory cytokines and glial cells, especially microglial cells, have been implicated in persistent pain sensitization. Less is known about the role of astrocytes in pain regulation. This study aimed to observe the expression of the astrocytic biomarker glial fibrillary acidic protein (GFAP) and the serum levels of interleukin 1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α) after short-term administration of central pain relievers in rats not submitted to noxious stimuli. Male Wistar rats were divided into five groups, receiving for nine days- (1) amitriptyline (Amt-10 mg/kg/day, by gavage); (2) gabapentin (Gb-60 mg/kg/day, by gavage; (3) methadone (Me-4.5 mg/kg/day, intraperitoneal route [IP]); (4) morphine (Mo-10 mg/kg/day, IP); or (5) 0.9% saline solution, IP. Brain samples were collected for immunohistochemical study of GFAP expression in the mesencephalon and nucleus accumbens (NAc). The area of GFAP-positive cells was calculated using MetaMorph software and serum levels of IL-1β and TNF-α were measured by enzyme-linked immunosorbent assay. Serum TNF-α levels were decreased in the groups treated with Mo, Me and Gb, but not in the Amt-treated group. IL-1β decreased only in rats treated with Me. The astrocytic expression of GFAP was decreased in the brainstem with all drugs, while it was increased in the NAc with Amt, Me and Mo

Reverse Engineering of an Aspirin-Responsive Transcriptional Regulator in Escherichia coli

Bacterial transcription factors (TFs) are key devices for the engineering of complex circuits in many biotechnological applications, yet there are few well-characterized inducer-responsive TFs that could be used in the context of an animal or human host. We have deciphered the inducer recognition mechanism of two AraC/XylS regulators from Pseudomonas putida (BenR and XylS) for creating a novel expression system responsive to acetyl salicylate (i.e., aspirin). Using protein homology modeling and molecular docking with the cognate inducer benzoate and a suite of chemical analogues, we identified the conserved binding pocket of BenR and XylS. By means of site-directed mutagenesis, we identified a single amino acid position required for efficient inducer recognition and transcriptional activation. Whereas this modification in BenR abolishes protein activity, in XylS, it increases the response to several inducers, including acetyl salicylic acid, to levels close to those achieved by the canonical inducer. Moreover, by constructing chimeric proteins with swapped N-terminal domains, we created novel regulators with mixed promoter and inducer recognition profiles. As a result, a collection of engineered TFs was generated with an enhanced response to benzoate, 3-methylbenzoate, 2-methylbenzoate, 4-methylbenzoate, salicylic acid, aspirin, and acetylsalicylic acid molecules for eliciting gene expression in E. coli.Fil: Monteiro, Lummy Maria Oliveira. Universidade de Sao Paulo; BrasilFil: Arruda, Leticia Magalhães. Universidade de Sao Paulo; BrasilFil: Sanches Medeiros, Ananda. Universidade de Sao Paulo; BrasilFil: Martins Santana, Leonardo. Universidade de Sao Paulo; BrasilFil: Alves, Luana de Fátima. Universidade de Sao Paulo; BrasilFil: Defelipe, Lucas Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Turjanski, Adrian Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Guazzaroni, Mara Eugenia. Universidade de Sao Paulo; BrasilFil: de Lorenzo, Victor. Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología; EspañaFil: Silva Rocha, Rafael. Universidade de Sao Paulo; Brasi

Indiscipline and the sense of justice in high school teenagers.

O objetivo foi de averiguar a noção de justiça retributiva, mais precisamente entre os alunos indisciplinados e disciplinados e observar a prevalência dos dois tipos de reações: expiatórias ou de reciprocidade. Verificar o conceito de disciplina e de indisciplina entre professores e alunos e a estes pedirpara atribuir um juízo de valor. Os resultados demonstraram que os professores partiram de várias categorias para definir disciplina e indisciplina e as priorizadas foram comportamento, aprendizagem e motivação. Para os alunos ocorreram diferenças na preferência de categorias. Quanto à atribuição de valor a grande maioria, 92,59%, considera que ser indisciplinado não é algo bom. Quanto à prevalência dos dois tipos de reações expiatórias ou de reciprocidade relativas à sanção, os alunos consideraram como mais severa e justa as sanções por reciprocidade e preferiram punir através da mesma. Porém, é grande o número de alunos que optou pelas sanções expiatórias.The aim was to analyze the sense of retributive justice, particularly, among the undisciplined and disciplined students, and to observe which type of reaction prevails: expiatory or reciprocity. The teachers and students were asked about their conceptions of discipline and indiscipline. They were also asked to attribute a value judgment. Results showed that the teachers based themselves on several categories to define discipline and indiscipline, and the main were behavior, learning and motivation. As for the students, the preference for the categories differed. In attributing a judgment value, the great majority of 92,59% considers indiscipline not good. Regarding the prevailing type of reaction, expiatory or reciprocity, students consider more severe and fair the reciprocity sanction and they would rather punishment to be in such way. It was also high, though, the number of students who preferred the expiatory sanctions

Systematization of nursing care to children and adolescents in psychological distress

Objetivo:Elencar os principais diagnósticos, intervenções e resultados de enfermagem descritos pela NANDA Internacional (NANDA-I), NursingOutcomes Classification (NOC), Nursing Intervention Classification (NIC), para crianças e adolescentes em sofrimento psíquico fundamento na teoria da recuperação em saúde mental-Teria da Mare de Baker. Método: Estudo descritivo exploratório com abordagem qualitaitiva, realizado CAPSi da Secretaria Executiva da Regional IV (SER IV), do município de Fortaleza – CE.  Para a análise dos dados utilizou-se a estruturação dos dados coletados e o raciocínio diagnóstico Resultados: Inicialmente, foram pré-selecionados 28 diagnósticos de enfermagem, prevalecendo seis. Conclusão: Com a aplicação da sistematização da assistência de enfermagem (SAE) os enfermeiros vêm de forma singular e diferenciada, buscando promover uma reintegração dessas pessoas com transtornos mentais na sua própria família e sociedade