299 research outputs found

    Impacto del ejercicio y depresión en estudiantes de nivel superior; caso Universidad Autónoma del estado de México

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    Se define ejercicio como “la actividad física planificada, estructurada y repetitiva que busca como fin mejorar la condición física de la persona y estar más saludable” (Instituto Universitario Amerike, 2019). En cuanto a la depresión, se refiere a un “conjunto de síntomas de predominio afectivo, y que en mayor o menor grado, también están presentes síntomas de tipo cognitivo, volitivo y somático, por lo que podría hablarse de una afectación global psíquica y física” (Gobierno de Aragón, 2019). “La depresión se caracteriza principalmente por la presencia de tristeza, pérdida de interés o placer, sentimientos de culpa o falta de autoestima, trastornos del sueño o del apetito, sensación de cansancio y falta de concentración” (OMS, 2018b). Las diversas interacciones complejas entre los factores sociales (Estrés), psicológicos (Trauma) y biológicos (Alteraciones en el sistema nervioso), pueden influir para que se desarrolle este trastorno mental. La depresión afecta en el mundo a 121 millones de personas, de los que menos del 25% tienen acceso a tratamientos efectivos y advierte que una de cada cinco personas llegará a desarrollar un cuadro depresivo en su vida, aumentando este número si concurren otros factores como enfermedades médicas o situaciones de estrés. Además, es previsible, que en el año 2020, la depresión pase a convertirse en la segunda causa más común de discapacidad, después de las enfermedades cardiovasculares. En cuanto al sedentarismo, es uno de los principales factores de riesgo de mortalidad a nivel mundial, reportándose que, uno de cada cuatro adultos no tiene un nivel suficiente de ejercicio (OMS, 2018a). La Encuesta Nacional de Salud y Nutrición (ENSANUT, 2012) determinó “una prevalencia del 16.5% sobre síntomas depresivos clínicamente significativos en adultos de 20 años o más”. Mientras que el Instituto Nacional de Estadística y Geografía (INEGI, 2017b), “documentó que 32.5 millones de personas se han sentido deprimidas”. Referente al ejercicio los resultados no son muy gratos, “menos de la mitad de la población de 18 años y más (41.7%) realiza deporte o ejercicio físico. El porcentaje de activos físicamente es mayor en hombres (48.4%) que mujeres (35.6%)” (INEGI, 2017a).La impresionante prevalencia que la depresión ha tenido en los últimos años y el poco o nulo ejercicio que realiza la población adulta, ha hecho sospechar una posible relación entre estas variables. Se elaboró un estudio cuantitativo no experimental, transversal, tipo descriptivo, correlacional y explicativo, aplicando instrumentos como Escala de Hamilton, Prueba del escalón de Harvard corta y un cuestionario con ítems: Sexo, edad y si realizaban o no ejercicio físico. La muestra fue de 22 estudiantes ambos sexos con el objetivo de Establecer el impacto del ejercicio físico en la depresión. Se determinó que 63.6% de los estudiantes no realizan ejercicio, 90.9% tienen una condición física pobre y un 68.2% presentan sintomatología depresiva

    Reconocimiento de las condiciones del mercado para el establecimiento de alianzas estratégicas de la Universidad de La Salle con empresas colombianas y mexicanas en la producción y comercialización del almidón nativo y resistente de Ñame, AR

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    Este trabajo busca reconocer las condiciones del mercado en Colombia y en otros países de la región, específicamente en México, para el establecimiento de alianzas de la Universidad de La Salle con el Gobierno Nacional, con el sector empresarial y académico así como con otras entidades públicas y privadas en la producción y comercialización del Almidón nativo y Resistente de Ñame (AR)

    Acuerdo Transatlántico para el Comercio y la Inversión entre la Unión Europea y los Estados Unidos

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    La Unión Europea y los Estados Unidos de Norteamérica se encuentran negociando un mega- acuerdo comercial denominado “Acuerdo Transatlántico para el Comercio y la Inversión (ATCI)”, cuyo objetivo es eliminar los aranceles y reducir barreras no arancelarias como las diferencias arbitrarias en las regulaciones y normas de la industria para productos, servicios e inversión exterior directa. Esta negociación se está llevando a cabo fuera de la órbita de la Organización Mundial del Comercio (OMC). El contenido de las negociaciones hace suponer que en el caso de firmarse dicho acuerdo el mismo generará un fuerte impacto en el comercio internacional.The European Union and the United States of America are negotiating a mega-trade agreement called the "Transatlantic Agreement for Trade and Investment" (TTIP), which aims to eliminate tariffs and reduce barriers, arbitrary differences in regulations and industry standards for products, services and direct foreign investment. This negotiation is taking place outside the orbit of the World Trade Organization (WTO). The content of the negotiations suggest that in the case of signing such an agreement, it will have a strong impact on international trade.Facultad de Ciencias Jurídicas y Sociale

    Association of burning mouth syndrome with xerostomia and medicines

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    Objetivo: Identificar factores de riesgo para el síndrome de boca ardiente (SBA) a través de estudio de casos y controles. Material y métodos: Se realizó análisis cuantitativo del flujo salival total en reposo y estimulado; se registraron la xerostomía subjetiva, el consumo de medicamentos y los estados psicológicos de ansiedad y depresión en 40 pacientes con SBA y 40 controles. Resultados: El análisis ANOVA mostró diferencias significativas en las medias del número de medicamentos/día, número de medicamentos xerostomizantes/día, xerostomía subjetiva, ansiedad y depresión, entre los grupos estudiados. No se observaron diferencias significativas en las tasas de flujo salival en reposo y estimulado. El análisis de asociación Odds ratio determinó asociación del SBA con xerostomía y con el consumo de hipotensores y diuréticos. Conclusiones: Según los resultados de este estudio, se puede afirmar que el consumo de hipotensores y diuréticos fue un factor de riesgo para el padecimiento del SBA. La función de las glándulas salivales en los pacientes con SBA no está deteriorada

    Insights on Microbial Communities Inhabiting Non-Volcanic Hot Springs

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    The dataset of the metagenome supporting the conclusions of this article is available in the MG-RAST repository: https://www.mg-rast.org/linkin.cgi?project=mgp84238 (accessed on 3 October 2022).[Abstract] The northwest of Spain has an abundance of non-volcanic hot springs that, until recently, had only been used for thermalism activities. One of such hot springs, Muiño da Veiga, has now been explored using metagenomics to study the microbial community that inhabits these high-temperature circumneutral continental waters. Sequencing of the metagenome allowed the characterization of its composition, diversity, metabolic connections and potential as a source for thermozymes, as well as its ability to assemble MAGs. A diverse microbial community dominated by Bacteria domain members was revealed, particularly from the early-branching Aquificales group. The most abundant genus was Sulfurihydrogenibium, known for its implication in sulfur cycling and for forming mats that enable novel niches. The variety of primary producers with autotrophic pathways (and specifically the sulfur oxidizing pathway) expands the range of available nutrients, and the increase in biomass forms thicker mats, resulting in more available niches and broader microbial diversity. Nonetheless, certain metabolic pathways were attributed to less abundant members of the microbial community, reinforcing the idea that the rare biosphere plays important roles in the network of interactions present in an ecosystem and acts as genetic reservoirs. In addition, three of the assembled MAGs represent novel microbial diversity found in this hot spring. Moreover, the presence of enzymes and microorganisms with possible biotechnological applications was confirmed, including proteases, lipases and cell-wall degrading enzymes, pointing to the potential for the hot spring as a source for thermozymes.This research was funded by XUNTA DE GALICIA “Consolidación GRC” co-financed by FEDER, Grant Number ED431C 2020/08, and MINISTERIO DE CIENCIA, INNOCACIÓN Y UNIVERSIDADES (MICINN), Grant Number RTI2018-099249-B-I00. J.-J.E.-R. received a predoctoral fellowship from UNIVERSIDADE DA CORUÑA/INDITEX “Axudas para estadías predoutorais INDITEX-UDC 2016”, budget identification 0400470001 422D 48700. J.-J.E.-R. received a predoctoral fellowship from CENTRO DE INVESTIGACIONES CIENTIFICAS AVANZADAS/INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE A CORUÑA. “Agrupación CICA-INIBIC: ayudas para estancias pre y postdoctorales 2016”, budget identification 6100240002 541A 6490211Xunta de Galicia; ED431C 2020/08https://www.mg-rast.org/linkin.cgi?project=mgp8423

    Early predictors of corticosteroid response in acute severe autoimmune hepatitis: a nationwide multicenter study

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    Early predictors; Corticosteroid; Autoimmune hepatitisPredictors primerencs; Corticosteroides; Hepatitis autoimmunePredictores tempranos; Corticosteroide; Hepatitis autoinmuneBackground and Aims To assess whether corticosteroids improve prognosis in patients with AS-AIH, and to identify factors at therapy initiation and during therapy predictive of the response to corticosteroids. Methods This was a retrospective cohort study including all patients with AS-AIH admitted to 13 tertiary centres from January 2002 to January 2019. The composite primary outcome was death or liver transplantation within 90 days of admission. Kaplan–Meier and Cox regression methods were used for data analysis. Results Of 242 consecutive patients enrolled (mean age [SD] 49.7 [16.8] years), 203 received corticosteroids. Overall 90-day transplant-free survival was 61.6% (95% confidence interval [CI] 55.4–67.7). Corticosteroids reduced the risk of a poor outcome (adjusted hazard ratio [HR] 0.25; 95% CI 0.2–0.4), but this treatment failed in 30.5%. An internally validated nomogram composed of older age, MELD, encephalopathy and ascites at the initiation of corticosteroids accurately predicted the response (C-index 0.82; [95% CI 0.8–0.9]). In responders, MELD significantly improved from days 3 to 14 but remained unchanged in non-responders. MELD on day 7 with a cut-off of 25 (sensitivity 62.5%[95% CI: 47.0–75.8]; specificity 95.2% [95% CI: 89.9–97.8]) was the best univariate predictor of the response. Prolonging corticosteroids did not increase the overall infection risk (adjusted HR 0.75; 95% CI 0.3–2.1). Conclusion Older patients with high MELD, encephalopathy or ascites at steroid therapy initiation and during treatment are unlikely to show a favourable response and so prolonged therapy in these patients, especially if they are transplantation candidates, should be avoided.This study was supported in part by grants from the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III, number PI20/01302, awarded to Agustín Albillos and number PI 21/01310, awarded to Luis Téllez. CIBEREHD is funded by the Instituto de Salud Carlos III using grants cofinanced by the European Development Regional Fund “A way to achieve Europe” (EDRF). María Carlota Londoño received support from the Plan Nacional de I+D+I co-funded by ISCIII-Subdirección General de Evaluación and Fondo Europeo de Desarrollo Regional (FEDER-"Una manera de Hacer Europa") (PI17/00955). Laura Patricia Llovet received the Resident Award “Clínic-La Pedrera” granted by the Hospital Clínic de Barcelona, Research, Innovation and Education Department

    The Personal Wellbeing among Community-Dwelling Older Adults in Spain and Associated Factors

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    Objective: The conceptual framework of Quality of Life (QoL) allows approaching the knowledge of the living conditions of people in order to help establishing policies for QoL improvement. This study is aimed at examining the assessment made by older adults on their personal wellbeing and the satisfaction with life and the associated factors. A summary of the psychometric properties of the measurement instrument was also presented. Method: The data came from the Ageing in Spain Longitudinal Study, Pilot Survey (ELES-PS), carried out in 2011 among people 50 years old or more living in family housing in Spain. The Personal Wellbeing Index (PWI), as a multidimensional measure of QoL, was used to evaluate the subjective wellbeing. Personal, social and residential characteristics were considered as independent variables. Descriptive statistical analysis, ANOVA, correlation, factor and regression analyses were applied. Results and conclusions: The PWI had good psychometric properties and showed the convergent validity with satisfaction with life as a whole (SWLW). Unidimensional structure of the scale was also demonstrated. PWI and SWLW total scores reached 74.5%SM and 77.1%SM, respectively. The best rated life domains were the satisfaction with relationships, safety and feeling part of the community. The SWLW observed significant differences in gender categories while PWI within age and social status. Both scales were associated with marital status, educational level, household size, current activity status and social status. The regression model of the PWI explained 34.2% of the variance through factors on socio-demographic and economic resources, psychosocial, health/functioning, family and social networks, leisure and residential environment. Based on these results, it would be desirable to deepen on this line from a longitudinal perspective to detect the influence of the changing conditions of the aged people in their personal well-being and life satisfaction.This research was funded by the Spanish Ministry of Science and Innovation (National R&D&I Plan: ref. CSO2009-08645-E/SOCI, CSO2009-06638-E/SOCI, CSO2009-06637-E/SOCI), by the Fundación Obra Social Cajamadrid and by the Basque Government, and supported by the Ageing Process Research Unit INGEMA-CSIC, for carrying out the ELES Project Pilot Survey. Another grant from the Spanish Ministry of Science and Innovation (National R&D&I Plan: ref. CSO2011-30210-C02-01) was endorsed for the analysis. Authors would like to thank the editor and the anonymous reviewer/s for their helpful comments during the development of this paper

    Tridimensional assessment of the dental follicle dimensions of impacted mandibular third molars using cone-beam CT

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    The present study was performed to compare follicle dimensions of impacted mandibular third molar (IMTM) with different impaction angulations using cone beam computed tomography (CBCT). Forty-nine individuals with IMTM (24 male, 25 female) were selected. Their age range was 25-55 years. The sample was divided into three IMTM groups either vertical (n=16), mesioangular (n=18) or horizontal (n=15) position based on Winter?s classification (the angle between the longitudinal axis of the second and third molars). Follicular spaces (FS) from available CBCT imaging were measured from the midpoint of the teeth?s crown in several dimensions (mesial, distal, occlusal, apical, vestibular and lingual) in axial, sagittal and coronal planes. An ANOVA, T-student, Kruskal?Wallis and Mann-Whitney U tests were used. A comparison of the mesial FS for all groups revealed significant differences (p<0.001). Significant difference was also found for vestibular FS between the vertical and mesioangular IMTM groups (p=0.04). Buccolingual FS for all groups revealed no significant differences (p=0.074), whereas significant difference was found for the vertical and horizontal IMTM groups (p=0.02). No significant statistical differences were found for occlusal (p=0.54), apical (p=0.06), and lingual (p=0.64) FS. In this sample IMTM follicles have different dimensions according to their degree of angulation. Mesioagulated and horizontally positioned IMTMs seems to consistently have some increased FS dimensions (mesial and vestibular aspects)

    Genetic diversity of meat quality related genes in Argentinean pigs

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    Genetic influence on pork quality exists between breeds and within a breed. The variation is caused by a large set of genes, and pork quality traits have a multifactorial background. Research into the genetics of meat quality found causative mutations associated with marked effects on pig meat value. This study aimed to investigate the segregation of meat quality-related SNPs and compare their diversity and genetics in commercial and Creole pigs from different farms in the North-West of Argentina. A screen for SNPs in RYR1, PRKAG3, CAST, and SOX6 candidate genes and the differentiation of their genotypes by PCR–RFLP was conducted. All genes were characterized by a high level of polymorphism and heterozygosity, and populations showed no differences in the genetic structure for the analyzed SNPs. These results highlighted the role of pig genotypes as a source of basic variability potentially affecting processed meat products and fresh meat.Fil: Rodríguez, Viviana Rita. Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación; ArgentinaFil: Maffioly, J. I.. Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación; ArgentinaFil: Zdanovicz, L. A.. Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación; ArgentinaFil: Fabre, Romina María. Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación; ArgentinaFil: Barrandeguy, Maria Eugenia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Departamento de Genética; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas; ArgentinaFil: García, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas | Universidad Nacional de Misiones. Instituto de Biología Subtropical. Instituto de Biología Subtropical - Nodo Posadas; Argentina. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Departamento de Genética; ArgentinaFil: Lagadari, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación; Argentin

    Differential neurophysiological correlates of retrieval of consolidated and reconsolidated memories in humans: An ERP and pupillometry study

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    Consolidated memories can return to a labile state if they are reactivated by unpredictable reminders. To persist, active memories must be re-stabilized through a process known as reconsolidation. Although there is consistent behavioral evidence about this process in humans, the retrieval process of reconsolidated memories remains poorly understood. In this context, one fundamental question is whether the same or different neurophysiological mechanisms are involved in retrieval of consolidated and reconsolidated memories. Because it has been demonstrated that the exposure to the reconsolidation process may restructure and strengthen memories, we hypothesized distinct neurophysiological patterns during retrieval of reconsolidated memories. In addition, we hypothesized that interfering with the reconsolidation process using a new learning can prevent these neurophysiological changes. To test it, consolidated, reconsolidated and declarative memories whose reconsolidation process was interfered (i.e., picture-word pairs) were evaluated in humans in an old/new associative recall task while the brain activity and the pupillary response were recorded using electroencephalography and eyetracking. Our results showed that retrieval of reconsolidated memories elicits specific patterns of brain activation, characterized by an earlier peak latency and a smaller magnitude of the left parietal ERP old/new effect compared to memories that were only consolidated or whose reconsolidation process was interfered by a new learning. Moreover, our results demonstrated that only retrieval of reconsolidated memories is associated with a late reversed mid-frontal effect in a 600–690 time window. Complementarily, memories that were reactivated showed an earlier peak latency of the pupil old/new effect compared to non-reactivated memories. These findings support the idea that reconsolidation has an important impact in how memories are retrieved in the future, showing that retrieval of reconsolidated memories is partially supported by specific brain mechanisms.Fil: Campos Arteaga, G.. Pontificia Universidad Católica de Chile; ChileFil: Forcato, Cecilia. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Wainstein, G.. Pontificia Universidad Católica de Chile; Chile. The University of Sydney,; AustraliaFil: Lagos, R.. Universidad de Chile; ChileFil: Palacios García, I.. Pontificia Universidad Católica de Chile; Chile. Universidad Diego Portales; ChileFil: Artigas, C.. Pontificia Universidad Católica de Chile; ChileFil: Morales, R.. Pontificia Universidad Católica de Chile; ChileFil: Pedreira, Maria Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Rodríguez, E.. Pontificia Universidad Católica de Chile; Chil
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