Semigroups with fixed multiplicity and embedding dimension

Given m is an element of N, a numerical semigroup with multiplicity m is called a packed numerical semigroup if its minimal generating set is included in {m, m + 1 , ..., 2m - 1}. In this work, packed numerical semigroups are used to build the set of numerical semigroups with a given multiplicity and embedding dimension, and to create a partition of this set. Wilf's conjecture is verified in the tree associated to some packed numerical semigroups. Furthermore, given two positive integers m and e, some algorithms for computing the minimal Frobenius number and minimal genus of the set of numerical semigroups with multiplicity m and embedding dimension e are provided. We also compute the semigroups where these minimal values are achieved

Cysteine and cysteine-related signaling pathways in arabidopsis thaliana

Cysteine occupies a central position in plant metabolism because it is a reduced sulfur donor molecule involved in the synthesis of essential biomolecules and defense compounds. Moreover, cysteine per se and its derivative molecules play roles in the redox signaling of processes occurring in various cellular compartments. Cysteine is synthesized during the sulfate assimilation pathway via the incorporation of sulfide to O-acetylserine, catalyzed by O-acetylserine(thiol)lyase (OASTL). Plant cells contain OASTLs in the mitochondria, chloroplasts, and cytosol, resulting in a complex array of isoforms and subcellular cysteine pools. In recent years, significant progress has been made in Arabidopsis, in determining the specific roles of the OASTLs and the metabolites produced by them. Thus, the discovery of novel enzymatic activities of the less-abundant, like DES1 with L-cysteine desulfhydrase activity and SCS with S-sulfocysteine synthase activity, has provided new perspectives on their roles, besides their metabolic functions. Thereby, the research has been demonstrated that cytosolic sulfide and chloroplastic S-sulfocysteine act as signaling molecules regulating autophagy and protecting the photosystems, respectively. In the cytosol, cysteine plays an essential role in plant immunity; in the mitochondria, this molecule plays a central role in the detoxification of cyanide, which is essential for root hair development and plant responses to pathogens.Ministerio de Economía y Competitividad BIO2010-15201Junta de Andalucía CVI-719

Signaling in the plant cytosol: cysteine or sulfide?

Cysteine (Cys) is the first organic compound containing reduced sulfur that is synthesized in the last stage of plant photosynthetic assimilation of sulfate. It is a very important metabolite not only because it is crucial for the structure, function and regulation of proteins but also because it is the precursor molecule of an enormous number of sulfur-containing metabolites essential for plant health and development. The biosynthesis of Cys is accomplished by the sequential reaction of serine acetyltransferase (SAT) and O-acetylserine(thiol)synthase (OASTL). In Arabidopsis thaliana, the analysis of specific mutants of members of the SAT and OASTL families has demonstrated that the cytosol is the compartment where the bulk of Cys synthesis takes place and that the cytosolic OASTL enzyme OAS-A1 is the responsible enzyme. Another member of the OASTL family is DES1, a novel L-cysteine desulfhydrase that catalyzes the desulfuration of Cys to produce sulfide, thus acting in a manner opposite to that of OAS-A1. Detailed studies of the oas-a1 and des1 null mutants have revealed the involvement of the DES1 and OAS-A1 proteins in coordinate regulation of Cys homeostasis and the generation of sulfide in the cytosol for signaling purposes. Thus, the levels of Cys in the cytosol strongly affect plant responses to both abiotic and biotic stress conditions, while sulfide specifically generated from the degradation of Cys negatively regulates autophagy induced in different situations. In conclusion, modulation of the levels of Cys and sulfide is likely critical for plant performance

A mechanistic study on the potential of quinolinium salts as photocatalysts for the abatement of chlorinated pollutants

[EN] Photocatalytic degradation of three highly chlorinated contaminants, namely 2,4,6-trichlorophenol (TCP), 2,4,6-trichloroanisole (TCA) and 5-chloro-2-(2,4-dichlorophenoxy)phenol (triclosan, TCS) has been investigated in the presence of N-methylquinolinium tetrafluoroborate (NMQ(+)), a photocatalyst able to act via Type I or Type II mechanism. Photodegradation of contaminants under aerobic conditions was achieved within hours; and it was accompanied by mineralization, as demonstrated by trapping of the evolved carbon dioxide as barium carbonate. Moreover, a high degree of detoxification, based on % inmobilization of daphnids (Daphnia magna bioassay), was reached after 70 h of irradiation. Quenching of the NMQ(+) fluorescence by the pollutants was evidenced by a decrease in the emission intensity and lifetime. Detection of the reduced NMQ. by laser flash photolysis in the presence of the pollutants provided an unambigous evidence of the electron transfer process. Quenching of singlet oxygen by the contaminants showed the typical singlet oxygen quenching constants (10(5)-10(6) M-1 s(-1)). Evaluation of the relative contribution of both pathways (Type I vs Type II) point to the photodegradation occurring via a Type I mechanism, being the contribution of Type II mechanism negligible at any concentration range.Financial support from Spanish Government (Grant SEV-2016.0683 and CTQ2015-69832-C4) and generous contribution from Generalitat Valenciana (Prometeo Program) are gratefully acknowledged. We also thank support from VLC/Campus. R Martinez-Haya thanks financial support from Spanish Government (Grant SEV-2012-0267).Martínez-Haya, R.; Sabater Marco, C.; Castillo López, M.; Miranda Alonso, MÁ.; Marín García, ML. (2018). A mechanistic study on the potential of quinolinium salts as photocatalysts for the abatement of chlorinated pollutants. Journal of Hazardous Materials. 351:277-284. https://doi.org/10.1016/j.jhazmat.2018.03.010S27728435

Energías renovables y cambios de usos del suelo en el sur de la Península Ibérica: una lectura territorial de la política energética

La lucha contra el cambio climático necesita de una transformación del modelo energético que está siendo fuertemente apoyado desde las políticas de la Unión Europea y de los estados miembros. La materialización espacial de la política energética de fomento de las energías renovables es un elemento crucial que ha de concretarse sobre los usos de suelo pre-existentes, lo que a su vez provoca cambios sobre los ecosistemas y los paisajes. Este artículo investiga la implantación territorial de las plantas eólicas y solares en la Península Ibérica para evaluar qué tipos de usos del suelo están siendo más afectados. A partir de la evolución de la política energética en España y Portugal se analizan de forma comparada los desarrollos de plantas eólicas y solares y los usos del suelo utilizando la cartografía temática publicada tanto en España como en Portugal entre 2005 y 2020. Los resultados de la investigación constatan la exclusividad de estos desarrollos en ámbitos rurales, destacando la sustitución de cultivos herbáceos junto con cubiertas de matorral y pastizal, provocando una alteración significativa de las economías y los paisajes rurales.info:eu-repo/semantics/publishedVersio

Diferenciales de bonos soberanos y primas de CDS en la zona euro: un análisis de causalidad

This article presents an analysis of the possible relationship between the spreads of sovereign bonds and the premia of credit default swaps (CDS) to determine whether they are useful tools for the measurement of the sovereign risk either separately or by taking into account the joint evolution of their values. The data refer to ten countries in the Eurozone along 2008¿2016. By applying the causality Granger test for these variables, after six different ways of proxy, CDS premia are found to be the cause of the risk spreads in certain cases, although a bidirectional relationship is predominant in many other cases. So the CDS market contains clear and highly useful information on the sovereign riskEste artículo presenta un análisis de la posible relación existente entre los diferenciales de los bonos soberanos y las primas de las permutas financieras de riesgo de impago (CDS, Credit Default Swap), con el objeto de determinar si son herramientas útiles para la medida del riesgo soberano de forma separada o teniendo en cuenta ambas variables. Se toman datos de 10 países de la Eurozona para el periodo 2008-2016. Aplicando el test de causalidad de Granger para esas variables, después de utilizar seis formas distintas de comparación de diferenciales, se concluye que la prima del CDS causa el diferencial de riesgo de crédito en suficientes ocasiones, aunque predomina una relación bidireccional. Así que el mercado de CDS contiene información clara y útil para la evolución del riesgo soberano.Universidad Pablo de Olavid

Energías renovables y cambios de usos del suelo en el sur de la Península Ibérica: una lectura territorial de la política energética

La lucha contra el cambio climático necesita de una transformación del modelo energético que está siendo fuertemente apoyado desde las políticas de la Unión Europea y de los estados miembros. La materialización espacial de la política energética de fomento de las energías renovables es un elemento crucial que ha de concretarse sobre los usos de suelo pre-existentes, lo que a su vez provoca cambios sobre los ecosistemas y los paisajes. Este artículo investiga la implantación territorial de las plantas eólicas y solares en la Península Ibérica para evaluar qué tipos de usos del suelo están siendo más afectados. A partir de la evolución de la política energética en España y Portugal se analizan de forma comparada los desarrollos de plantas eólicas y solares y los usos del suelo utilizando la cartografía temática publicada tanto en España como en Portugal entre 2005 y 2020. Los resultados de la investigación constatan la exclusividad de estos desarrollos en ámbitos rurales, destacando la sustitución de cultivos herbáceos junto con cubiertas de matorral y pastizal, provocando una alteración significativa de las economías y los paisajes rurales

MAP17 and SGLT1 Protein Expression Levels as Prognostic Markers for Cervical Tumor Patient Survival

MAP17 is a membrane-associated protein that is overexpressed in human tumors. Because the expression of MAP17 increases reactive oxygen species (ROS) generation through SGLT1 in cancer cells, in the present work, we investigated whether MAP17 and/or SGLT1 might be markers for the activity of treatments involving oxidative stress, such as cisplatin or radiotherapy. First, we confirmed transcriptional alterations in genes involved in the oxidative stress induced by MAP17 expression in HeLa cervical tumor cells and found that Hela cells expressing MAP17 were more sensitive to therapies that induce ROS than were parental cells. Furthermore, MAP17 increased glucose uptake through SGLT receptors. We then analyzed MAP17 and SGLT1 expression levels in cervical tumors treated with cisplatin plus radiotherapy and correlated the expression levels with patient survival. MAP17 and SGLT1 were expressed in approximately 70% and 50% of cervical tumors of different types, respectively, but they were not expressed in adenoma tumors. Furthermore, there was a significant correlation between MAP17 and SGLT1 expression levels. High levels of either MAP17 or SGLT1 correlated with improved patient survival after treatment. However, the patients with high levels of both MAP17 and SGLT1 survived through the end of this study. Therefore, the combination of high MAP17 and SGLT1 levels is a marker for good prognosis in patients with cervical tumors after cisplatin plus radiotherapy treatment. These results also suggest that the use of MAP17 and SGLT1 markers may identify patients who are likely to exhibit a better response to treatments that boost oxidative stress in other cancer types. © 2013 Perez et al.This work was supported by grants from the Spanish Ministry of Science and Innovation and FEDER funds (SAF2009-08605), Consejeria de Ciencia e Innovacion and Consejeria de Salud of the Junta de Andalucia (CTS-6844 and PI-0142) and FIS (PI12/00137). AC’s laboratory is also funded by a fellowship from the Fundacion Oncologica FERO, supported by Fundació Josep Botet.Peer Reviewe

Factores psicológicos y dolor en pacientes reumáticos

Este trabajo estudia 40 pacientes reumáticos del Hospital del S.V.S. de Alicante distribuidos en 4 grupos (Lupus, Artritis Reumatoide, Espondilitis Anquilosante y Síndrome Fibromiálgico Primario). Hemos analizado las posibles relaciones entre la ansiedad como rasgo de personalidad, el neuroticismo, el estrés atribuido a la enfermedad, características sociodemográficas y variables relativas al dolor (intensidad, frecuencia, limitación y actividad diaria). Los resultados muestran una relación positiva, pero débil, entre la ansiedad y el neuroticismo con algunas variables de dolor. Las características sociodemográficas son las que presentan las relaciones más fuertes y frecuentes con las variables de dolor.This work studies 40 rheumatic out-patients (Lupus, Rheumatoid Arthritis, Ankylosing Spondylitis and Primary Fibromyalgia Syndrome) from the Alicante General Hospital. We analyzed the relationships between trait-anxiety, neuroticism, stress appraisal, sociodemographic characteristics and pain variables (intensity, frequency, limitation and daily activity). Results show a positive, but weak, relationships of the trait-anxiety and neuroticism to pain variables. The strongest and the most frequent relationships with pain variables were showed for the sociodemographic characteristics.Este trabajo ha sido realizado con la ayuda de investigación PA85-0336 de la Comisión Asesora de investigación Científica y Técnica (CAICYT), Ministerio de Educación

Promotion of a sustainable gastronomy: the program El Setrill of Radio UA

Fundamentos: La pérdida de los referentes alimentarios, culinarios y gastronómicos propios de la dieta mediterránea, se traduce en un deterioro del estado nutricional y en una mayor incidencia de sobrepeso, obesidad y problemas de salud asociados, entre otras consecuencias. Frente al alejamiento de los parámetros de la cultura alimentaria mediterránea parece oportuno desarrollar estrategias que ayuden a su recuperación. Hacerlo de la mano de la nutrición y la gastronomía puede resultar clave. Los objetivos son analizar la experiencia del programa El Setrill emitido en Radio UA y abordar la utilidad de la divulgación radiofónica como estrategia didáctica y como instrumento para la promoción de una gastronomía sostenible. Métodos: Bajo el título de El Setrill, con el valenciano y el castellano como lenguas vehiculares, durante el curso académico 2017-2018 se inició en Radio UA la emisión de un programa radiofónico de 30 minutos sobre gastronomía, tradiciones culinarias y salud. Lo lleva a cabo un equipo su multidisciplinar conformado por dos periodistas, dos dietistas-nutricionistas, un cocinero con formación en enfermería y antropología, y un historiador de la ciencia con formación médica. Resultados: Se han realizado 21 programas en 3 temporadas, con temáticas que han abordado desde el aceite de oliva a la cocina de cuaresma, pasando por distintos arroces, la compra de proximidad, o los productos de temporada, entre otros. Con más de 15000 visualizaciones y reproducciones y una media de 732 por programa. Conclusiones: La experiencia ha mostrado la utilidad y las posibilidades del medio radiofónico como instrumento de divulgación científica, complemento formativo y promotor de una gastronomía saludable y sostenible basada en las tradiciones culinarias.Background: The loss of food, culinary and gastronomic references typical of the Mediterranean diet results in a deterioration of the nutritional status and a higher incidence of overweight, obesity and associated health problems, among other consequences. In this context, it seems appropriate to develop strategies that will help to recover the parameters of the Mediterranean food culture. Doing so hand in hand with nutrition and gastronomy can be the key. The objectives are to analyse the experience of the programme El Setrill broadcast on Radio UA and to tackle the usefulness of radio broadcasting as an educational strategy and as an instrument for the promotion of sustainable gastronomy. Methods: Under the title of El Setrill, with Valencian and Spanish as the vehicular languages, during the 2017-2018 academic year, a 30-minute radio programme on gastronomy, culinary traditions and health was started on Radio UA. It is carried out by a multidisciplinary team made up of two journalists, two dieticians, a cook with studies in nursing and anthropology, and a science historian with medical degrees. Results: 21 programs have been carried out in 3 seasons, with themes that have covered everything from olive oil to Lenten cooking, including different rice dishes, local shopping and seasonal products, among others. With more than 15,000 views and reproductions and an average of 732 per programme. Conclusions: Revista Española de Nutrición Comunitaria Revista Española de Nutrición Comunitaria Revista Española de The experience has shown the utility and the possibilities of radio as a tool for popularizing science, a formative complement and a promoter of healthy and sustainable gastronomy based on culinary traditions