78 research outputs found

    Assessing competences in sustainability in teaching degrees and post-degrees: a proposal of a tool

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    Este estudio presenta una revisión de competencias genéricas en sostenibilidad (CS) en Educación Superior y proporciona una compilación de estas CS mediante una rúbrica que sirve como instrumento para evaluar el nivel de adquisición de las CS de los estudiantes universitarios en el campo de la educación. La rúbrica ha sido diseñada, analizada y contrastada por un grupo de investigadores de diferentes universidades vinculados al campo de la educación. Ha sido adaptada a los grados y posgrados de educación de ocho universidades y está estructurada en tres niveles de dominio en la adquisición de las competencias. Esta rúbrica puede ser un instrumento útil para la evaluación de la CS en los grados de educación del sistema universitario español.This study presents a review on the generic competences in sustainability (CS) at higher education and provides a compilation of these CS through a rubric that serves as a tool to assess the level of CS acquisition among university students of teacher training. The rubric has been designed, analysed and contrasted by a group of researchers from different universities linked to teacher training courses. It has been adapted to different undergraduate and postgraduate teaching programs at eight universities. It is structured in three levels of competency acquisition. This rubric can be a useful instrument for the assessment of CS in the degrees of education in the Spanish university system

    Liver injury in non-alcoholic fatty liver disease is associated with urea cycle enzyme dysregulation

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    The main aim was to evaluate changes in urea cycle enzymes in NAFLD patients and in two preclinical animal models mimicking this entity. Seventeen liver specimens from NAFLD patients were included for immunohistochemistry and gene expression analyses. Three-hundred-and-eighty-two biopsy-proven NAFLD patients were genotyped for rs1047891, a functional variant located in carbamoyl phosphate synthetase-1 (CPS1) gene. Two preclinical models were employed to analyse CPS1 by immunohistochemistry, a choline deficient high-fat diet model (CDA-HFD) and a high fat diet LDLr knockout model (LDLr −/−). A significant downregulation in mRNA was observed in CPS1 and ornithine transcarbamylase (OTC1) in simple steatosis and NASH-fibrosis patients versus controls. Further, age, obesity (BMI > 30 kg/m), diabetes mellitus and ALT werefound to be risk factors whereas A-allele from CPS1 was a protective factor from liver fibrosis. CPS1 hepatic expression was diminished in parallel with the increase of fibrosis, and its levels reverted up to normality after changing diet in CDA-HFD mice. In conclusion, liver fibrosis and steatosis were associated with a reduction in both gene and protein expression patterns of mitochondrial urea cycle enzymes. A-allele from a variant on CPS1 may protect from fibrosis development. CPS1 expression is restored in a preclinical model when the main trigger of the liver damage disappears.The research leading to these results has received funding from the Consejería de Salud de la Junta de Andalucía under grant agreement PC-0148-2016-0148 and PE-0451-2018 and Instituto de Salud Carlos III under grant agreements CD21/00095, PI16/01842, PI19/01404, PI19/00589, IFI18/00041, FI20/00201, CD18/00126 and EHD18PI04/2021. Rocío Gallego-Durán has received the Andrew K Burroughs Fellowship from European Association for the Study of the Liver (EASL), Aprendizaje de Nuevas Tecnologías fellowship from Asociación Española para el Estudio del Hígado (AEEH) and CIBERehd Grant to support researcher’s mobility

    Born Too Early and Too Small: Higher Order Cognitive Function and Brain at Risk at Ages 8-16

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    Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear. We conducted a longitudinal study to first identify clinical predictors of ultrasound brain abnormalities in 196 children born very preterm (VP; gestational age 32 weeks) and with very low birth weight (VLBW; birth weight 1500 g). At ages 8–16, the subset of VP-VLBW children without neurological findings (124) were invited for a neuropsychological assessment and an MRI scan (41 accepted). Of these, 29 met a rigorous criterion for MRI quality and an age, and gender-matched control group (n = 14) was included in this study. The key findings in the VP-VLBW neonates were: (a) 37% of the VP-VLBW neonates had ultrasound brain abnormalities; (b) gestational age and birth weight collectively with hospital course (i.e., days in hospital, neonatal intensive care, mechanical ventilation and with oxygen therapy, surgeries, and retinopathy of prematurity) predicted ultrasound brain abnormalities. At ages 8–16, VP-VLBW children showed: a) lower intelligent quotient (IQ) and executive function; b) decreased gray and white matter (WM) integrity; (c) IQ correlated negatively with cortical thickness in higher order processing cortical areas. In conclusion, our data indicate that facets of executive function and IQ are the most affected in VP-VLBW children likely due to altered higher order cortical areas and underlying W

    Issues Year 3. Number 6. Journal of the School of Social Sciences, Humanities and Arts

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    Las opiniones contenidas en los artículos de esta revista no vinculan a la institución sino que son de exclusiva responsabilidad de los autores, dentro de los principios democráticos de cátedra libre y libertad de expresión, consagrados en el artículo 3° del Estatuto General de la Corporación Universidad Autónoma de Bucaramanga. El material de esta publicación puede ser reproducido sin autorización, siempre que se mencione su procedencia y la escuela de Ciencias Sociales, Humanidades y Artes de la UNA. reciba un ejemplar de su publicación.Presentación. - 5 Educación y porpensión a aprender y a enseñar. - 13 La formación del profesorado universitario. - 29 Vigencia de los principios de Juan Amos Comenio en las prácticas pedagógicas actuales. - 37 Dámaso Zapata: "Héroe de la paz en las Américas". - 43 Clima social de los centros educativos y hostigamiento psicológico - Una lectura socioconstructiva desde los sistemas autoritarios- . -49 El aprendizaje: Dos perspectivas diferentes del mismo proceso. - 61 La experiencia del aprendizaje mediado: Una opción para el cambio de actitutd del maestro. - 71 El diseño de ambientes de aprendizaje desde una visión constructivista. - 79 Hacia la construcción de preescolares lúdico-científicos colombianos. - 89 Travesía por Nireneotor: Una experiencia de aprendizaje por medio de un ambiente virtual. - 97 Las competencias científicas en el proceso de formaicón de escolares. - 111The opinions contained in the articles of this journal do not bind the institution but are the exclusive responsibility of the authors, within the democratic principles of free teaching and freedom of expression, enshrined in article 3 of the General Statute of the University Corporation. Autonomous of Bucaramanga. The material in this publication may be reproduced without authorization, provided that its origin and the UNA School of Social Sciences, Humanities and Arts are mentioned. receive a copy of your publication

    Memoria del IV Coloquio Internacional sobre Diversidad Cultural y Estudios Regionales

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    Esta memoria del IV Coloquio Internacional sobre Diversidad Cultural y Estudios Regionales: Escenarios de la heterogeneidad, memorias y culturas, realizada por el Centro de Investigaciones sobre Diversidad Cultural y Estudios Regionales, CIDICER, en 2016, compila las ponencias presentadas, las cuales se organizan por ejes temáticos, en 7 apartados: Culturas, Identidades e Imaginarios, Literatura Cultura e Identidades, Estéticas de la Heterogeneidad, Pluriculturalidad y Grupos Minoritarios, Diversidad Cultural e Identidades, Literatura, Identidades y Género.UCR::Sedes Regionales::Sede de Occidente::Recinto San Ramón::Centro de Investigaciones sobre Diversidad Cultural y Estudios Regionales (CIDICER

    Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

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    The authors wish to make the following corrections to this paper [...]

    Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

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    (1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery
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