Structural Achitecture of the Madrid Basin from 3D Gravity Inversion

The Madrid Basin is an intraplate Cenozoic basin located in the central area of the Iberian Peninsula. Basement is characterized by a wide range of lithologies, from meta-sediments to granites. Sedimentary section is associated with a carbonatic platform in Cretaceous time and with continental environments during Tertiary. During the second half of the last century 2D seismic data was acquired and some wells were drilled by several oil & gas companies. Due to the lack of refraction seismic, the geometry of the Moho is not very well-known in the area. This study presents the results of the 3D gravity inversion performed mainly to determine the configuration of the Moho. Also, the geometry of basement has been refined after the inversion. The initial model was constrained by surface geology, 2D seismic and well data. The final 3D model shows significant density variations within the basement and the presence of an intra-basement structure in the Central Iberian System

New Insights on Peniche Basin (West Iberian Margin) Crustal Structure Based on Gravity Data Interpretation

A gravimetric study has been carried out over a sector of the West Iberian Margin (WIM), constrained by well and seismic data. The analytic development was made through three main stages: the processing of different gravity datasets, the production of gravity anomaly maps and 2,5D models using the processed data, and the geophysical interpretation of maps and models. The final results of the interpretation achieved, allowed the determination of crustal structure and its variation/complexity along the WIM. The main obtained results concern the pre-saline infilling and the deep structure of the margin, which vary related to the location of first-order oblique fractures

El factor humano en la prevención de riesgos laborales en los nuevos entornos de trabajo en la construcción 4.0

A pesar de los grandes avances alcanzados en prevención de riesgos laborales, hoy en día cuatro personas mueren por minuto a causa de enfermedades profesionales y accidentes de trabajo, muchos de ellos atribuidos a los comportamientos peligrosos de los trabajadores o a sus características individuales. Para minimizarlos, los campos de aplicación de la prevención de riesgos laborales se han centrado en los últimos años sobre el factor humano, siendo actualmente una de las líneas de estudio e investigación prioritarias de la IV Revolución Industrial. La industria 4.0 requiere operadores cualificados para el control y la gestión del conjunto de procesos digitalizados, este salto tecnológico debe ser asumido por los trabajadores, no como una barrera o un limitante de sus capacidades, sino como herramienta de apoyo. Al aprovechar de forma eficiente los sistemas tecnológicos de la cuarta revolución industrial optimizan tiempo, recursos y fomentan un entorno laboral con menos riesgos. En este contexto el presente trabajo analiza las oportunidades existentes del desarrollo de nuevos modelos de prevención y control de los riesgos en los contextos ocupacionales de la Construcción 4.0 desde la ergonomía cognitiva y el error humano.Despite the great advances made in the prevention of occupational risks, four people die per minute today due to occupational diseases and work accidents, many of them attributed to the dangerous behavior of workers or their individual characteristics. To minimize them, the fields of application of the prevention of occupational risks have focused in the last years on the human factor, being currently one of the priority study and research lines of the IV Industrial Revolution. Industry 4.0 requires qualified operators to control and manage the set of digitized processes, this technological leap must be assumed by the workers, not as a barrier or a limitation of their capabilities, but as a support tool. By efficiently leveraging the technological systems of the fourth industrial revolution, they optimize time, resources and foster a work environment with fewer risks. In this context, the present work analyzes the existing opportunities for the development of new models for the prevention and control of risks in the occupational contexts of Construction 4.0 from cognitive ergonomics and human error.Plan Propio de la Universidad de Sevilla Proyecto: 2017/0000096

Resección guiada por fluorescencia en pacientes con cáncer de lengua

ResumenIntroducciónLa fluorescencia ha sido utilizada exitosamente como pesquisa del cáncer oral, adicional al examen oral convencional, identifica áreas con cambios histológicos que son desapercibidas con luz blanca.ObjetivoSaber si la resección guiada por fluorescencia se asocia a márgenes quirúrgicos negativos en pacientes con cáncer de lengua.Material y métodosSe incluyó a pacientes con carcinoma invasivo de lengua candidatos a resección. Se evaluaron con examen oral convencional y con fluorescencia determinándose si el límite de la lesión coincidía en ambos exámenes, se marcaron los límites quirúrgicos analizándose histológicamente.ResultadosFueron 30 pacientes con carcinoma epidermoide invasivo; 10 T1, 15 T2 y 5 T3; 18 mujeres y 12 hombres. El borde de la lesión neoplásica evaluado con el examen oral convencional coincidió con la evaluación con fluorescencia en 17 (56%) y en 13 (44%) la lesión fue mayor. Los márgenes de quirúrgicos fueron negativos en 27 (90%) y positivos en 3 (10%), los positivos lo fueron en el espesor lingual, todos fueron cT3.ConclusionesLa fluorescencia identifica lesiones mayores a las diagnosticadas con el examen oral convencional en el 44% de los pacientes, favorece resección quirúrgica con márgenes negativos en el 90%, la infiltración submucosa y muscular no puede ser detectada por este método.AbstractBackgroundFluorescence has been successfully used as screening method of oral cavity cancer. In addition to the conventional oral examination, it identifies areas with histological changes that are not identified with conventional white light.ObjectiveTo determine whether fluorescence facilitates resection with negative margins in patients diagnosed with squamous cell carcinoma of the tongue.Material and methodsPatients diagnosed with invasive tongue squamous cell carcinoma were evaluated with a conventional oral examination and fluorescence. To determine whether the threshold of injury coincided in both tests, the limits of section were identified and histologically evaluated.ResultsThe study included 30 patients, 18 women and 12 men; 10 T1, 15 T2, and 5 patients with T3. The neoplastic margin evaluated with conventional light coincided with fluorescence in 17 patients (56%), and in 13 (44%) fluorescence identified a larger tumour. Surgical margins were negative in 27 (90%), and 3 (10%) positives that were all in the tongue thickness and with bulky tumours (T3).ConclusionsFluorescence identifies larger tumours than those identified with conventional oral examination in 44% of patients, and ensures a longer surgical resection with free surgical margins in 90% of cases. Submucosal and muscular invasion is not detected by this method

Seguimiento de las guías españolas para el manejo del asma por el médico de atención primaria: un estudio observacional ambispectivo

Objetivo Evaluar el grado de seguimiento de las recomendaciones de las versiones de la Guía española para el manejo del asma (GEMA 2009 y 2015) y su repercusión en el control de la enfermedad. Material y métodos Estudio observacional y ambispectivo realizado entre septiembre del 2015 y abril del 2016, en el que participaron 314 médicos de atención primaria y 2.864 pacientes. Resultados Utilizando datos retrospectivos, 81 de los 314 médicos (25, 8% [IC del 95%, 21, 3 a 30, 9]) comunicaron seguir las recomendaciones de la GEMA 2009. Al inicio del estudio, 88 de los 314 médicos (28, 0% [IC del 95%, 23, 4 a 33, 2]) seguían las recomendaciones de la GEMA 2015. El tener un asma mal controlada (OR 0, 19, IC del 95%, 0, 13 a 0, 28) y presentar un asma persistente grave al inicio del estudio (OR 0, 20, IC del 95%, 0, 12 a 0, 34) se asociaron negativamente con tener un asma bien controlada al final del seguimiento. Por el contrario, el seguimiento de las recomendaciones de la GEMA 2015 se asoció de manera positiva con una mayor posibilidad de que el paciente tuviera un asma bien controlada al final del periodo de seguimiento (OR 1, 70, IC del 95%, 1, 40 a 2, 06). Conclusiones El escaso seguimiento de las guías clínicas para el manejo del asma constituye un problema común entre los médicos de atención primaria. Un seguimiento de estas guías se asocia con un control mejor del asma. Existe la necesidad de actuaciones que puedan mejorar el seguimiento por parte de los médicos de atención primaria de las guías para el manejo del asma. Objective: To assess the degree of compliance with the recommendations of the 2009 and 2015 versions of the Spanish guidelines for managing asthma (Guía Española para el Manejo del Asma [GEMA]) and the effect of this compliance on controlling the disease. Material and methods: We conducted an observational ambispective study between September 2015 and April 2016 in which 314 primary care physicians and 2864 patients participated. Results: Using retrospective data, we found that 81 of the 314 physicians (25.8%; 95% CI 21.3–30.9) stated that they complied with the GEMA2009 recommendations. At the start of the study, 88 of the 314 physicians (28.0%; 95% CI 23.4–33.2) complied with the GEMA2015 recommendations. Poorly controlled asthma (OR, 0.19; 95% CI 0.13–0.28) and persistent severe asthma at the start of the study (OR, 0.20; 95% CI 0.12–0.34) were negatively associated with having well-controlled asthma by the end of the follow-up. In contrast, compliance with the GEMA2015 recommendations was positively associated with a greater likelihood that the patient would have well-controlled asthma by the end of the follow-up (OR, 1.70; 95% CI 1.40–2.06). Conclusions: Low compliance with the clinical guidelines for managing asthma is a common problem among primary care physicians. Compliance with these guidelines is associated with better asthma control. Actions need to be taken to improve primary care physician compliance with the asthma management guidelines

Análisis de la sensibilidad de las estimaciones de la profundidad del basamento en la cuenca de Madrid (España Central)

The Madrid basin, over 20.000 km2 , located in Central Spain. Its evolution is conditioned by basement uplifts (Central System and Toledo Mountains) during the Alpine orogeny. The Madrid basin is connected with the Loranca basin at its NE corner and with La Mancha basin to the south. Sediment thickness accumulated from Late Cretaceous to the Late Miocene, is about 3.000 m at Pradillo well, but from seismic interpretation, a depocenter associated to Central System South Thrust is inferred. For this study four different methodologies were used(“Euler Deconvolution”, “Source Parameter Imaging”, “Analytic Signal” and “Tilt Depth”), in order to obtain depth to basement estimations from aermagnetic data. These methods work for simplified source geometries, estimating depths as a good starting point for a structural interpretation. In Madrid Basin, this knowledge is important due to the geothermal and hydrological potential of the basin, as well as for CO2 storage. [RESUMEN]La cuenca de Madrid, con un área aproximada de 20.000 km2, se extiende en la zona central de la Península Ibérica. Su evolución está condicionada por el levantamiento del Sistema Central y de los Montes de Toledo durante la orogenia Alpina. La cuenca de Madrid está conectada con las cuencas de Loranca, en su límite NE, y de La Mancha por el sur. El espesor de sedimentos, con registro continuo desde el Cretácico Superior hasta el Mioceno Superior, alcanza los 3000 m en el pozo Pradillo, aunque de la interpretación sísmica se obtiene un depocentro, de mayor profundidad, adosado al cabalgamiento del Borde Sur del Sistema Central . En este trabajo se han seguido distintas metodologías para estimar la profundidad del basamento, a partir de datos aeromagnéticos. Los distintos métodos (“Deconvolucion de Euler”, “Source Parameter Imaging”, “Analytic Signal” y “Tilt Depth”) tienen en común que asumen geometrías sencillas, pero los resultados obtenidos resultan de gran interés para la interpretación estructural del basamento. En el caso de la cuenca de Madrid, este conocimiento es muy importante dado su potencial geotérmico e hidrogeológico, así como un posible uso como almacenamiento geológico

Concordancia interobservador de hallazgos cardiopulmonares en la radiografía de tórax entre radiólogos y médicos generales de un servicio de urgencias

Objetivo: estimar la concordancia inter-observador de hallazgos cardiopulmonares en la radiografía de tórax de adultos entre dos grupos independientes de radiólogos y médicos generales. Materiales y métodos: dos grupos de evaluadores, uno de radiólogos (n=2) y uno de médicos generales (n=5) valoraron 100 radiografías de tórax. Los ítems de evaluación fueron la calidad técnica radiológica, la normalidad de la radiografía y 27hallazgos radiológicos comunes en la consulta de urgencias. Los evaluadores calificaron la posibilidad de encontrar los hallazgos específicos en la radiografía (cinco por cada placa) en un formato similar a un script de concordancia, con escala de respuesta tipo Likert. El cálculo de concordancia se realizó con el estadístico kappa por grupos de Vanbelle (κ2g). Resultados: los grados de concordancia entre radiólogos y médicos generales fueron débiles para la identificación de hallazgos cardiopulmonares (κ2g 0,46; IC 95 % 0,43 – 0,51), calidad de la imagen (κ2g 0,44; IC 95 % 0,35 –0,53) y determinación de normalidad (κ2g 0,58; 0,44 – 0,72). Los índices de prevalencia fueron elevados (mín. – max.: 0,59 - 0,85) en la valoración de normalidad de las placas. Conclusiones: El grado de acuerdo en la determinaciónde normalidad puede estar subestimado por un alto índice deprevalencia. El poco tiempo de formación en radiología y de experiencia en el campo de los médicos generales podrían estar asociados al bajo grado de acuerdo entre los grupos

Subsidence and thermal history of an inverted Late Jurassic-Early Cretaceous extensional basin (Cameros, North-central Spain) affected by very low- to low-grade metamorphism

The Cameros Basin (North Spain) is a Late Jurassic‐Early Cretaceous extensional basin, which was inverted during the Cenozoic. It underwent a remarkable thermal evolution, as indicated by the record of anomalous high temperatures in its deposits. In this study, the subsidence and thermal history of the basin is reconstructed, using subsidence analysis and 2D thermal modelling. Tectonic subsidence curves provide evidence of the occurrence of two rapid subsidence phases during the syn‐extensional stage. In the first phase (Tithonian‐Early Berriasian), the largest accommodation space was formed in the central sector of the basin, whereas in the second (Early Barremian‐Early Albian), it was formed in the northern sector. These rapid subsidence phases could correspond to relevant tectonic events affecting the Iberian Plate at that time. By distinguishing between the initial and thermal subsidence and defining their relative magnitudes, Royden's (1986) method was used to estimate the heat flow at the end of the extensional stage. A maximum heat flow of 60–65 mW/m2 is estimated, implying only a minor thermal disturbance associated with extension. In contrast with these data, very high vitrinite reflectance, anomalously distributed in some case with respect to the typical depth‐vitrinite reflectance relation, was measured in the central‐northern sector of the basin. Burial and thermal data are used to construct a 2D thermal basin model, to elucidate the role of the processes involved in sediment heating. Calibration of the thermal model with the vitrinite reflectance (%Ro) and fluid inclusion (FI) data indicates that in the central and northern sectors of the basin, an extra heat source, other than a typical rift, is required to explain the observed thermal anomalies. The distribution of the %Ro and FI values in these sectors suggests that the high temperatures and their distribution are related to the circulation of hot fluids. Hot fluids were attributed to the hydrothermal metamorphic events affecting the area during the early post‐extensional and inversion stages of the basin.Funding for this research was provided by Spanish Government Projects CGL2008‐ 01648/BTE, CGL2008‐04916/BTE, CGL2011‐22709 and the Consolider‐Ingenio 2010 programme, under CSD 2006‐0004 “Topo‐Iberia”, by the UCM‐CM (Universidad Complutense Madrid Community) and by the INCAR‐CSIC – Oviedo.Peer reviewe

Petroleum systems modelling in a fold-and-thrust belt setting: the inverted Cameros basin, north-central Spain

The Mesozoic Cameros Basin, northern Spain, was inverted during the Cenozoic Alpine orogeny when the Tithonian – Upper Cretaceous sedimentary fill was uplifted and partially eroded. Tar sandstones outcropping in the southern part of the basin and pyrobitumen particles trapped in potential source rocks suggest that hydrocarbons have been generated in the basin and subsequently migrated. However, no economic accumulations of oil or gas have yet been found. This study reconstructs the evolution of possible petroleum systems in the basin from initial extension through to the inversion phase, and is based on structural, stratigraphic and sedimentological data integrated with petrographic and geochemical observations. Petroleum systems modelling was used to investigate the timing of source rock maturation and hydrocarbon generation, and to reconstruct possible hydrocarbon migration pathways and accumulations. In the northern part of the basin, modelling results indicate that the generation of hydrocarbons began in the Early Berriasian and reached a peak in the Late Barremian – Early Albian. The absence of traps during peak generation prevented the formation of significant hydrocarbon accumulations. Some accumulations formed after the deposition of post‐extensional units (Late Cretaceous in age) which acted as seals. However, during subsequent inversion, these reservoir units were uplifted and eroded. In the southern sector of the basin, hydrocarbon generation did not begin until the Late Cretaceous due to the lower rates of subsidence and burial, and migration and accumulation may have taken place until the initial phases of inversion. Sandstones impregnated with bitumen (tar sandstones) observed at the present day in the crests of surface anticlines in the south of the basin are interpreted to represent the relics of these palaeo‐accumulations. Despite a number of uncertainties which are inherent to modelling the petroleum systems evolution of an inverted and overmature basin, this study demonstrates the importance of integrating multidisciplinary and multi‐scale data to the resource assessment of a complex fold‐and‐thrust belt