5 research outputs found
Improvement of Physico-mechanical Properties of Partially Amorphous Acetaminophen Developed from Hydroalcoholic Solution Using Spray Drying Technique
- Publication venue
- Mashhad University of Medical Sciences
- Publication date
- 01/10/2013
- Field of study
Objective(s): This study was performed aiming to investigate the effect of particle engineering via spray drying of hydroalcoholic solution on solid states and physico-mechanical properties of acetaminophen. Materials and Methods: Spray drying of hydroalcoholic solution (25% v/v ethanol/water) of acetaminophen (5% w/v) in the presence of small amounts of polyninylpyrrolidone K30 (PVP) (0, 1.25, 2.5 and 5% w/w based on acetaminophen weight) was carried out. The properties of spray dried particles namely morphology, surface characteristics, particle size, crystallinity, dissolution rate and compactibility were evaluated. Results: Spray drying process significantly changed the morphology of acetaminophen crystals from acicular (rod shape) to spherical microparticle. Differential scanning calorimetery (DSC) and x-ray powder diffraction (XRPD) studies ruled out any polymorphism in spray dried samples, however, a major reduction in crystallinity up to 65%, especially for those containing 5% w/w PVP was observed. Spray dried acetaminophen particles especially those obtained in the presence of PVP exhibited an obvious improvement of the dissolution and compaction properties. Tablets produced from spray dried samples exhibited excellent crushing strengths and no tendency to cap. Conclusions: The findings of this study revealed that spray drying of acetaminophen from hydroalcoholic solution in the presence of small amount of PVP produced partially amorphous particles with improved dissolution and excellent compaction properties
Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
A study of drop size distribution and mean drop size in a perforated rotating disc contactor (PRDC)
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Glaucoma: Biological Trabecular and Neuroretinal Pathology with Perspectives of Therapy Innovation and Preventive Diagnosis
- Author
- Adachi
- Aguayo
- Ahmad
- Arnhold
- Auricchio
- Baden
- Bao
- Bartsch
- Bazvand
- Becker
- Bennett
- Bilotta
- Bodor
- Boland
- Bosworth
- Brelén
- Bull
- Bull
- Böcker-Meffert
- Cairns
- Cardillo
- Caspi
- Cennamo
- Chacko
- Chai
- Chai
- Chamling
- Chen
- Chen
- Chen
- Chen
- Chen
- Cheng
- Cheung
- Cho
- Chowdhury
- Chrysostomou
- Chung
- Coleman
- Conlon
- Connick
- Coombs
- Cordeiro
- Cordeiro
- Coxon
- Crigler
- Cui
- De Campos
- de Kater
- de Lima
- Di Polo
- Dobelle
- Dong
- Dorin
- Du
- Duan
- Erickson
- Fang
- Federico Tridico
- Fire
- Fischer
- Fischer
- Fogagnolo
- Franca
- Fujikado
- Gabelt
- Gage
- Gao
- Gao
- Giannelli
- Gionfriddo
- Gnavi
- Gonzalez
- Gonzalez-Garcia
- Guo
- Guo
- Gupta
- Guzman-Aranguez
- Hambright
- Hare
- Harvey
- Hiratani
- Hirooka
- Honjo
- Hoyer
- Hu
- Humayun
- Humayun
- Husain
- Ikeda
- Inman
- Inoue
- Izzotti
- Janssen
- Jha
- Ji
- Jiang
- Johnson
- Johnson
- Ju
- Ju
- Ju
- Kato
- Kelley
- Kersey
- Kim
- Kim
- King
- Kitaoka
- Klassen
- Ko
- Ko
- Krupin
- Ku
- Kurimoto
- Kurozumi
- Lamba
- Lambiase
- Lavik
- Lavinsky
- Lawrence
- Lebherz
- Lebrun-Julien
- Lee
- Lee
- Lee
- Lee
- Lewis
- Li
- Li
- Li
- Liaw
- Lin
- Liton
- Liu
- Liu
- Liu
- Lodi
- Lorach
- Lorber
- Luna
- Ma
- MacLaren
- Macoul
- Maguire
- Maguire
- Mandell
- Mansoor
- Mansour-Robaey
- Mansouri
- Maulvi
- McDowell
- McGowan
- McKinnon
- Mead
- Mead
- Mead
- Medeiros
- Meyer
- Meyer
- Mimeault
- Monem
- Moreno-Montañés
- Muller
- Munemasa
- Na
- Nafissi
- Negishi
- Neufeld
- Neufeld
- Neufeld
- Ngoi
- Nuzzi
- Nuzzi
- Nuzzi
- Nuzzi
- Nuzzi
- Nuzzi
- Nuzzi
- O'Donovan
- Okabe
- Okka
- Pajic
- Parameswaran
- Pardridge
- Park
- Pascolini
- Pate
- Pearson
- Pease
- Pease
- Pellegrini
- Peppas
- Perez
- Peterson
- Petrs-Silva
- Pezaris
- Pirhan
- Piri
- Pollack
- Polo
- Qi
- Qin
- Quigley
- Rabinowitz
- Raffaele Nuzzi
- Ramdas
- Rasmussen
- Raviola
- Realini
- Rong
- Rong
- Rosch
- Rudzinski
- Ruz
- Saati
- Saettone
- Sanes
- Sasaki
- Schmeer
- Sehic
- Sena
- Shearer
- Shi
- Shi
- Shin
- Shum
- Sieving
- Signore
- Simonelli
- Siu
- Sivaprasad
- Smith
- Song
- Spaide
- Stadtfeld
- Staples
- Stewart
- Stewart
- Sun
- Takahashi
- Tanihara
- Tatton
- Teng
- Tezel
- Tezel
- Tezel
- Tezel
- Thompson
- Tokushige
- Torab
- Tropepe
- Tsang
- Tucker
- Urtti
- Van de Velde
- Van de Velde
- Vecino
- Vercelli
- Vizzeri
- Vogel
- Vohra
- Ward
- Weinreb
- Weinreb
- Weiskrantz
- Weiss
- Weiss
- Weleber
- Wen
- West
- Whitson
- Wiederholt
- Wiederholt
- Wilke
- Wilkins
- Williams
- Wilmsmeyer
- Woodward
- Wordinger
- Wu
- Xie
- Xu
- Yang
- Ye
- Ying
- Young
- Yu
- Yu
- Zhang
- Zhong
- Zhou
- Zwart
- Publication venue
- 'Frontiers Media SA'
- Publication date
- Field of study
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- ?tinas A
- Aalem HAA
- Ababneh H
- Abbas A
- Abbas A
- Abbas H
- Abbasi A
- Abbassi F
- Abbasy J
- Abbood AH
- Abboud K
- Abdallah A
- Abdalsalam SJA
- Abdelaal A
- Abdelalemm M
- Abdelhafez MHZ
- Abdelhalim K
- Abdeljalil M
- Abdelkarem M
- Abdelmageed A
- Abdelmageed A
- Abdelmaksoud M
- Abdelmawgoud S
- Abdelmawla M
- Abdelmawla MOMK
- Abdelmoneim N
- Abdelnoor A
- Abdelrahman F
- Abdelrazek HA
- Abdelrhman R
- Abdelzaher A
- Abdelzaher AT
- Abdou K
- Abdoun M
- Abdualqader M
- Abdualqader MYM
- Abdulhaq A
- Abduljawad H
- Abdullaev A
- Abdullah NAN
- Abdulmonem A
- Abdulwahed E
- Abebrese J
- Abiyere H
- Abobakr AM
- Aboelfath S
- Abosamak NE
- Abu Harb Z
- Abu Hilal M
- Abu Hilal M
- Abu Jayyab M
- Abu-Elfatth AM
- Abu-Ghazal S
- Abu-Ghazal SY
- Abuali ASAME
- Abuelazm M
- Abuelnaga Y
- Abuelnaga Y
- Abughazal SY
- Abuleil A
- Abusannuga M
- Abuzaina K
- Adam I
- Aday U
- Adeyeye A
- Adeyeye NA
- Adham M
- Adhikari KM
- Affary AA
- Afzal A
- Afzal I
- Aghdassi A
- Ahmadi BE
- Ahmed EA
- Ahmed MBE
- Ahmed R
- Ahmeed
- Ajayi P
- Akahoshi K
- Akbar A
- Akhtar N
- Al-Abdi R
- Al-Abed O
- Al-Ameri S
- Al-Ameri SAAS
- Al-Asadi MAMM
- Al-Dowsh NA
- Al-Eryani F
- Al-Faiq S
- Al-Haj A
- Al-Hyari A
- Al-Isawi A
- Al-juaifari MA
- Al-Khawlani Q
- Al-Kubati W
- Al-Maadani B
- Al-Mallah R
- Al-Markiz E
- Al-Mekhlafi A
- Al-Melhani W
- Al-Naggar H
- Al-Naggar H
- Al-Ogaili M
- Al-Qasrawi S
- Al-Saban R
- Al-saban RAM
- Al-Sader MA-J
- Al-Samawi A
- Al-Samawi H
- Al-Sarireh B
- Al-Shami K
- Al-shami M
- Al-sharabi EAE
- Al-Shehari M
- Al-Tekreeti S
- Alahmed F
- Alahmed H
- Alaimo L
- Alali MB
- Alannaz O
- Alansary MN
- Alatise O
- Alattas Z
- Alawna R
- Alazab E
- Albaba S
- Albakry R
- Albar A
- Albaraesi MN
- Albarouni S
- Albishti A
- Alboridy M
- Aldoescu S
- AlDowsh NA
- Aldressi W
- Aldumaini H
- Alegria CR
- Alfano MS
- Alfatah MA
- Alfonso C
- Alfurais S
- Alghazo H
- Alhaboob N
- Alharthi M
- Alhashemi M
- Alhmaidi R
- Alhouri A
- Alhouri AN
- Ali AYM
- Ali D
- Ali RAAY
- Ali RAY
- Ali SB
- Alissawi S
- Alissawi SZ
- Aliwy MA
- Aljaber A
- Aljamal S
- Aljiffry M
- Alkhadem MA
- Alkhaleel W
- Alkhateb H
- Allah MA
- Allam A
- Allam M
- Allam S
- Allisiardi F
- Alloush A
- Almarashi H
- Almarkiz E
- Almasri TA
- Almassaudi A
- Almekhlafi T
- Almiani S
- Almjersah A
- Alnammourah WM
- Alnammourah WM
- Alnimr A
- Aloulou M
- Alowjali F
- Alsabah M
- Alsabbagh F
- AlSaffaf M
- Alsanany GM
- Alsayadi R
- Alshaghel M
- Alsharabi E
- Alshareea E
- Alsharif D
- Alsharif DS
- Alsharif DS
- Alsharif DS
- Alshatshat A
- Alsori M
- Alsoudani A
- Altatari A
- Altatari AM
- Alwafy K
- Alwan HM
- Alyasin I
- Alzabadiah AHM
- Alzghoul MW
- Alzoubi M
- Amarin Z
- Amic F
- Amina H
- Ammar K
- Amrani L
- Amrani ME
- Amro S
- Amro S
- Anas O
- Anas O
- Anastasi A
- Anatolievna LN
- Andersson B
- Andersson R
- Andrade JCB
- Andreou A
- Andreuccetti J
- Andriola V
- Andujar RL
- Ang D
- Angelico R
- Anghinoni M
- Aniukstyte L
- Anthoni C
- Antic A
- Antonucci A
- Anyla M
- Apel R
- Apers T
- Apostolos K
- Apostolou C
- Apostolou C
- Appeltans B
- Appeltans B
- Appukuttan M
- Arabiyat H
- Arabiyat HAA
- Arbutina D
- Arbutina D
- Ardhanari R
- Ardito F
- Argüello P
- Arıkan T
- Arıkan TB
- Arkadopoulos N
- Armentano S
- Arnau ABM
- Aroori S
- Artigues E
- Asano T
- Asghar M
- Atanasov B
- Atici AE
- Atici SD
- Atstupens K
- Attalla A
- Augustinus S
- Ausania F
- Avgerinos K
- Awad AK
- Awad S
- Awad S
- Awadi S
- Awan AA
- Aya B
- Aydin H
- Aydoğan S
- Ayoub S
- Azab MA
- Azaman NSBB
- Azizeh O
- Azizian A
- Azman A
- Azri YA
- Azzam A
- Babor R
- Babu E
- Bacalbaşa N
- Badovinac D
- Badr H
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- Badran Y
- Bagmet N
- Bahaa M
- Bahroun S
- Bahroun SG
- Bahroun SG
- Baiocchi GL
- Bairamidis E
- Bajjah H
- Bajjah HM
- Bajjah HMAH
- Balalis D
- Balci D
- Baldi C
- Balduzzi A
- Ballarin R
- Baltagiannis E
- Balzan S
- Bansal V
- Banting S
- Banting S
- Barakat A
- Barakat ATM
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- Barberis A
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- Barbu ST
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- Bareig E
- Bari H
- Barros AV
- Barroso RR
- Bartella I
- Bartlett A
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- Bassi C
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- Belkhadir Z
- Belli A
- Belloni E
- Beltran-Miranda P
- Belyaev A
- Belyaev O
- Benamwor A
- Bencini L
- Benkabbou A
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- Besselink M
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- Beugniez C
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- boumzebra Y
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- Bowne W
- Bozhkov VM
- Boñar NL
- Bracke B
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- Brennfleck FW
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- Elfarag HA
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- Ellafi AAD
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- Elnabi MH
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- Galeb KSA
- Galketiya KB
- Galun D
- Galun D
- Gamal M
- Ganai S
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- Gananadha S
- Garcea G
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- Garcia FOB
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- Garcia-Herrera JS
- García BM
- García LS
- García-Domingot MI
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- Garhy ME
- Garritano S
- Garulli G
- Garzali IU
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- Gerwash A
- Gerwash AA
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- Ghallab AAA
- Ghalleb M
- Ghamarnejad O
- Ghani S
- Ghani S
- Ghannam A
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- Ghazal A
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- Ghorbani P
- Ghunaim M
- Ghushaim M
- Giaccardi S
- Giacometti M
- Giacometti M
- Giakoustidis D
- Giani A
- Giannakopoulos T
- Giannone F
- Gianotti L
- Gianpaolo M
- Giardino A
- Ginghina O
- Giordano M
- Giorgakis E
- Giorgakis E
- Giovanni T
- Giraudo G
- Giuffrida M
- Giuliani A
- Giuliante F
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- Glantzounis G
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- Goh BKP
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- Toutouzas K
- Triantafyllidis I
- Tripathi M
- Trizzino A
- Troci A
- Troisi RI
- Trotovšek B
- TrotovŠek B
- Truant S
- Tsakiris C
- Tsalis K
- Tsaramanidis S
- Tschuor C
- Tsiotos G
- Tsirlis T
- Tsoukalas N
- Tumas J
- Tuvin D
- Tyutyunnik P
- Tzimas G
- Tölgyes T
- Türkoğlu MA
- Tüzüner A
- Uemura K
- Uggeri F
- Ugrekhelidze K
- Uguz A
- Uhl W
- Ulgur HS
- Ullah S
- Unalp OV
- Urciuoli I
- Uzir SSBM
- Uzunoglu FG
- Vaia A
- Vailas M
- Vaishnav D
- Val AR-D
- Valaroutsos A
- Valcarcel AQ
- Valente R
- Valeriia S
- Valladares AM
- Valmorisco MA
- Valverde DP
- Van Dam JL
- Van den Bossche B
- van Eijck CH
- van Laarhoven S
- Vanagas T
- Varshney V
- Vasavada B
- Vaslamatzis M
- Vass D
- Vassiliu P
- Vazquez PG
- Velagala JR
- Velagala JR
- Velenciuc N
- Velázquez PS
- Veneroni L
- Venkatesh NR
- Vennarecci G
- Vera V
- Vereczkei A
- Vezakis A
- Vigia E
- Vilcu M
- Vilhav C
- Vincenti L
- Virk S
- Vishnoi JR
- Viswanathan K
- Vito D
- Vivarelli M
- Vladov N
- Vodyala C
- Vougas V
- Vouros D
- Vrakopoulou GZ
- Waechter FL
- Waffa Z
- Wagner K
- Wahib EM
- Wake R
- Wang H
- Wang J
- Waqar U
- Waqar U
- Wardeh S
- Wardeszkiewicz A
- Wassmer C-H
- Weber M
- Wei A
- Wei K
- Wei K
- Weitz J
- Wellner U
- Welsch T
- Welsh F
- Wen D
- Wennerblom JH
- Wenning AS
- Wicherts D
- Wierzchowski M
- Wikar T
- Williamsson C
- Windsor J
- Winslow E
- Wlazlak M
- Wolfgang C
- Wu CH
- Wu CH
- Wyroślak-Najs J
- Wüllenweber H-P
- Yadav K
- Yadev I
- Yadev I
- Yaghan R
- Yamamoto T
- Yang P-C
- Yassin LMA
- Yassin R
- Yegen C
- Yeo C
- Yesilyurt D
- Yip V
- Yoong B
- Yoong BK
- Younes E
- Younes E
- Young A
- Yousef A
- Youssef A
- Yu M-C
- Zacharakis E
- Zacharoulis D
- Zachiotis M
- Zagainov V
- Zaharie F
- Zahed M
- Zahed MSM
- Zakaria AD
- Zamri FMB
- Zanatta M
- Zanello M
- Zanini N
- Zanus G
- Zanus G
- Zaruba P
- Zawia A
- Zayed A
- Zdujic P
- Zedelj J
- Zeh HJ
- Zentar A
- Zerbi A
- Zidan T
- Zidan T
- Zironda A
- Zitawi A
- Zivanovic M
- Zogopoulos G
- Zonta S
- Zonta S
- Zorrilla CF
- Zozaya G
- Zreqat Q
- Zuhdi Z
- Zuhdy M
- Zygomalas A
- álvarez PM
- çelik M
- çetiindağ Ö
- Çiftci AB
- çoker A
- öfkeli Ö
- özet A
- Šileikis A
- Šlepavičius A
- Štironja I
- Publication venue
- Publication date
- 18/01/2024
- Field of study