103 research outputs found
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Direct iminization of PEEK
Semi-crystalline poly(ether ketone)s are important high-temperature engineering thermoplastics, but are difficult to characterize at the molecular level because of their insolubility in conventional organic solvents. Here we report that polymers of this type, including PEEK, react cleanly at high temperatures with low-volatility aralkyl amines to afford stable, noncrystalline poly(ether-imine)s, which are readily soluble in solvents such as chloroform, THF and DMF and so characterizable by conventional size-exclusion chromatography
Multi-objective optimization of confidence-based localization in large-scale underwater robotic swarms.
Localization in large-scale underwater swarm robotic systems has increasingly attracted research and industry communities’ attention. An optimized confidence-based localization algorithm is proposed for improving localization coverage and accuracy by promoting robots with high confidence of location estimates to references for their neighboring robots. Confidence update rules based on Bayes filters are proposed based on localization methods’ error characteristics where expected localization error is generated based on measurements such as operational depth and traveled distance. Parameters of the proposed algorithm are then optimized using the Evolutionary Multi-objective Optimization algorithm NSGA-II for localization error and trilateration utilization minimization while maximizing localization confidence and Ultra-Short Base Line utilization. Simulation studies show that a wide localization coverage can be achieved using a single Ultra-Short Base Line system and localization mean error can be reduced by over 45% when algorithm’s parameters are optimized in an underwater swarm of 100 robots
Corpuscular model of two-beam interference and double-slit experiments with single photons
We introduce an event-based corpuscular simulation model that reproduces the
wave mechanical results of single-photon double slit and two-beam interference
experiments and (of a one-to-one copy of an experimental realization) of a
single-photon interference experiment with a Fresnel biprism. The simulation
comprises models that capture the essential features of the apparatuses used in
the experiment, including the single-photon detectors recording individual
detector clicks. We demonstrate that incorporating in the detector model,
simple and minimalistic processes mimicking the memory and threshold behavior
of single-photon detectors is sufficient to produce multipath interference
patterns. These multipath interference patterns are built up by individual
particles taking one single path to the detector where they arrive one-by-one.
The particles in our model are not corpuscular in the standard, classical
physics sense in that they are information carriers that exchange information
with the apparatuses of the experimental set-up. The interference pattern is
the final, collective outcome of the information exchanges of many particles
with these apparatuses. The interference patterns are produced without making
reference to the solution of a wave equation and without introducing signalling
or non-local interactions between the particles or between different detection
points on the detector screen.Comment: Accepted for publication in J. Phys. Soc. Jpn
Target Detection Performance Bounds in Compressive Imaging
This paper describes computationally efficient approaches and associated
theoretical performance guarantees for the detection of known targets and
anomalies from few projection measurements of the underlying signals. The
proposed approaches accommodate signals of different strengths contaminated by
a colored Gaussian background, and perform detection without reconstructing the
underlying signals from the observations. The theoretical performance bounds of
the target detector highlight fundamental tradeoffs among the number of
measurements collected, amount of background signal present, signal-to-noise
ratio, and similarity among potential targets coming from a known dictionary.
The anomaly detector is designed to control the number of false discoveries.
The proposed approach does not depend on a known sparse representation of
targets; rather, the theoretical performance bounds exploit the structure of a
known dictionary of targets and the distance preservation property of the
measurement matrix. Simulation experiments illustrate the practicality and
effectiveness of the proposed approaches.Comment: Submitted to the EURASIP Journal on Advances in Signal Processin
An approach to emotion recognition in single-channel EEG signals: a mother child interaction
In this work, we perform a first approach to emotion recognition from EEG single channel signals extracted in four (4) mother-child dyads experiment in developmental psychology -- Single channel EEG signals are analyzed and processed using several window sizes by performing a statistical analysis over features in the time and frequency domains -- Finally, a neural network obtained an average accuracy rate of 99% of classification in two emotional states such as happiness and sadness20th Argentinean Bioengineering Society Congress, SABI 2015 (XX Congreso Argentino de BioingenierÃa y IX Jornadas de IngenierÃa ClÃnica)28–30 October 2015, San Nicolás de los Arroyos, Argentin
Coding Efficiency of Fly Motion Processing Is Set by Firing Rate, Not Firing Precision
To comprehend the principles underlying sensory information processing, it is important to understand how the nervous system deals with various sources of perturbation. Here, we analyze how the representation of motion information in the fly's nervous system changes with temperature and luminance. Although these two environmental variables have a considerable impact on the fly's nervous system, they do not impede the fly to behave suitably over a wide range of conditions. We recorded responses from a motion-sensitive neuron, the H1-cell, to a time-varying stimulus at many different combinations of temperature and luminance. We found that the mean firing rate, but not firing precision, changes with temperature, while both were affected by mean luminance. Because we also found that information rate and coding efficiency are mainly set by the mean firing rate, our results suggest that, in the face of environmental perturbations, the coding efficiency is improved by an increase in the mean firing rate, rather than by an increased firing precision
Positioning pharmacists’ roles in primary health care: a discourse analysis of the compensation plan in Alberta, Canada
Abstract Background A comprehensive Compensation Plan for pharmacy services delivered by community pharmacists was implemented in Alberta, Canada in July 2012. Services covered by the Compensation Plan include care planning services, prescribing services such as adapting prescriptions, and administering a drug or publicly-funded vaccine by injection. Understanding how the Compensation Plan was framed and communicated provides insight into the roles of pharmacists and the potential influence of language on the implementation of services covered by the Compensation Plan by Albertan pharmacists. The objective of this study is to examine the positioning of pharmacists’ roles in documents used to communicate the Compensation Plan to Albertan pharmacists and other audiences. Methods Publicly available documents related to the Compensation Plan, such as news releases or reports, published between January 2012 and December 2015 were obtained from websites such as the Government of Alberta, Alberta Blue Cross, the Alberta College of Pharmacists, the Alberta Pharmacists’ Association, and the Blueprint for Pharmacy. Searches of the Canadian Newsstand database and Google identified additional documents. Discourse analysis was performed using social positioning theory to explore how pharmacists’ roles were constructed in communications about the Compensation Plan. Results In total, 65 publicly available documents were included in the analysis. The Compensation Plan was put forward as a framework for payment for professional services and formal legitimization of pharmacists’ changing professional roles. The discourse associated with the Compensation Plan positioned pharmacists’ roles as: (1) expanding to include services such as medication management for chronic diseases, (2) contributing to primary health care by providing access to services such as prescription renewals and immunizations, and (3) collaborating with other health care team members. Pharmacists’ changing roles were positioned in alignment with the aims of primary health care. Conclusions Social positioning theory provides a useful lens to examine the dynamic and evolving roles of pharmacists. This study provides insight into how communications regarding the Compensation Plan in Alberta, Canada positioned pharmacists’ changing roles in the broader context of changes to primary health care delivery. Our findings may be useful for other jurisdictions considering implementation of remunerated clinical services provided by pharmacists
Gut mucosal DAMPs in IBD: From mechanisms to therapeutic implications
Endogenous damage-associated molecular patterns (DAMPs) are released during tissue damage and have increasingly recognized roles in the etiology of many human diseases. The inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), are immune-mediated conditions where high levels of DAMPs are observed. DAMPs such as calprotectin (S100A8/9) have an established clinical role as a biomarker in IBD. In this review, we use IBD as an archetypal common chronic inflammatory disease to focus on the conceptual and evidential importance of DAMPs in pathogenesis and why DAMPs represent an entirely new class of targets for clinical translation. </p
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