De aquí para allá, sin o con caballo : Patagonia, 13.000 años de historia

A lo largo de 13.000 años Patagonia estuvo ocupada por poblaciones cazadorasrecolectoras sumamente móviles, con diversificada movilidad territorial, residencial y logística. Las complejas y extensas redes sociales que constituyeron permitieron la circulación de bienes, personas e ideas, condicionando los procesos de etnogénesis y los mecanismos de fisión y fusión social. A fines del Holoceno, la naturaleza de los desplazamientos nómadas y nuevas formas de interacción social y contacto provocaron importantes transformaciones sociales y económicas que desembocaron en una mayor jerarquización social y territorialidad.All along its 13.000 years, Patagonia was occupied by hunter-gatherer populations highly mobile, with diversified territorial, residential and logistic mobility. The complex and extensive social networks formed allowed the movement of goods, people and ideas, conditioning ethnogenesis processes, and mechanisms of social fission and fusion. In the late Holocene, the nature of nomadic movements and new forms of social interaction and contact caused major social and economic transformations that led to greater social hierarchy and territoriality

Reference priors based on composite likelihoods

In this paper we propose reference priors obtained by maximizing the average adivergence from the posterior distribution, when the latter is computed using a composite likelihood. Composite posterior distributions have already been considered in [7] and [8], when a full likelihood for the data is too complex or even not available. The use of a curvature corrected composite posterior distribution, as in [8], allows to apply the method in [6] for maximizing the asymptotic Bayes risk associated to an adivergence. The result is a Jeffreys type prior that is proportional to the square root of the determinant of the Godambe information matrix

Designing Magnetic NanoMOFs for Biomedicine: Current Trends and Applications

Metal–organic frameworks (MOFs) have shown a great potential in biomedicine due to their promising applications in different fields, including drug delivery, thermometry, theranostics etc. In this context, the development of magnetic sub-micrometric or nanometric MOFs through miniaturization approaches of magnetic MOFs up to the nanoscale still represents a crucial step to fabricate biomedical probes, especially in the field of theranostic nanomedicine. Miniaturization processes have to be properly designed to tailor the size and shape of particles and to retain magnetic properties and high porosity in the same material, fundamental prerequisites to develop smart nanocarriers integrating simultaneously therapeutic and contrast agents for targeted chemotherapy or other specific clinical use. An overview of current trends on the design of magnetic nanoMOFs in the field of biomedicine, with particular emphasis on theranostics and bioimaging, is herein envisioned

Ethnicity in patagonian hunter-gather: approaches from computational simulation

El objetivo de este trabajo es presentar una simulación computacional de las dinámicas de etnicidad en sociedades cazadoras recolectoras patagónicas. Entendiendo a la etnicidad como una categoría de relación social, consideramos que la revisión de este marco conceptual nos permitirá comprender su aplicación dentro del campo de la experimentación arqueológica

Etnicidad en cazadores-recolectores patagónicos:enfoques desde la simulación computacional

El objetivo de este trabajo es presentar una simulación computacional de las dinámicas de etnicidad en sociedades cazadoras recolectoras patagónicas. Entendiendo a la etnicidad como una categoría de relación social, consideramos que la revisión de este marco conceptual nos permitirá comprender su aplicación dentro del campo de la experimentación arqueológica.  &nbsp

The association between a body shape index and cardiovascular risk in overweight and obese children and adolescents

A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2±18 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass%detected by bioelectrical impedance analysis) and obesity- related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity

Evidence for preferences of Italian patients for physician attire

BACKGROUND: The relationship between patient and physician is a complex interaction that includes multiple factors. The objective of this study was to explore Italian patients' preferences regarding physician appearance. METHODS: A questionnaire was developed to survey patients in different medical and surgical settings; each subject was asked to choose one picture of either a male or female physician from a selection of different attires (professional, casual, surgical scrubs, trendy, and careless). Patients were also surveyed about issues such as the presence of a name tag, hair length, trousers on women, amount of makeup, presence of tattoos, and body piercing. Statistical analysis was performed using a Chi-square test. RESULTS: A total of 765 questionnaires (534 completed from patients waiting for an internal medicine visit and 231 for other subspecialties) were completed. The majority (45%) of patients preferred the gastroenterologist to wear a surgical scrub with a white coat. For the other specialists, patients accepted either scrubs or formal dress under a white coat (P ≤ 0.05), with a name tag. Trendy attire was preferred by nine patients (1.1%). The entire sample judged it inappropriate for clinicians to have long hair, visible tattoos, body piercing, and, for women, to wear trousers and use excessive makeup. CONCLUSION: This is the first study conducted in Italy regarding physician attire. As in other Western countries, Italian patients favor physicians in professional attire with a white coat. Wearing professional dress is part of "etiquette based medicine" and may favorably influence clinician-patient relationships and patient compliance.</br

Análisis etnoarqueológico del valor social del producto en sociedades cazadoras-recolectoras

This work was formulated as a consequence of considering the necessity of a value theory (that is, an economical theory), in archaeology. From our materialist perspective, that would allow us to set the basis for an objective analysis of past societies, understanding that only through the knowledge of their material life conditions and their social organization we would be able to know their historical becoming. We were reaching a common index that would make possible to compare different occupations and sites in Tierra del Fuego. This index would be used to make inferences about the amount of work invested in every occupation, amount of work that could be understood as the duration of the occupation or as the amount of people in that camp-site. On the other hand, on the basis of the Main Contradiciton formulation, we could establi sh a mechanism to quantify different participation in the production cycle and the existing differences in the access to the consumption of what has been produced. This will drive us to the formulation of a method to identify social explotation.Este trabajo surgió como consecuencia de varias preocupaciones. En primer lugar, considerábamos, desde hacía ya tiempo, la necesidad de una teoría del valor (económica, por tanto), en Arqueología; preocupación compartida con otros investigadores/as. Desde nuestra perspectiva materialista, ello nos había de permitir sentar las bases para un análisis objetivo de las sociedades prehistóricas, entendiendo que tan sólo a través delconocimiento de Las condiciones materiales de vida, y de la estructuración u organización de las relaciones sociales, podremos llegar a conocer el devenir histórico de las mismas. Buscábamos un índice, un común denominador, que nos permitiera poder comparar diferentes ocupaciones y yacimientos actualmente (y desde hace ya más de una década) en estudio en Tierra del Fuego (Argentina). Este índice debería permitirnos, por un lado realizar inferencias sobre la cantidad de trabajo invertida en cada ocupación de los diferentes asentamientos Yámana. Lo cual podría ser interpretado en clave de ti empo de ocupación o de cantidad de personas ocupando el sitio. Y por otro lado, y sobre la base de la formulación de la Contradicción Principal, podría establecer un mecanismo que nos permitiera cuantificar la participación diferencial en la producción y las disimetrías en el acceso al consumo de lo producido, estableciendo un «cálculo» para la identificación de la explotación. Este último interés tiene mucho que ver con el aceptado concepto de «sociedades igualitarias » aplicado a las sociedades cazadoras recolectoras, concepto cuestionable en tanto que surge de una aproximación androcéntrica. Este trabajo ha sido posible, en el caso de la sociedad Yámana, gracias a la exhaustiva y variada información etnográfica confrontada a una completa información arqueológica. El objetivo final es conseguir generar propuesta metodológica contrastada que nos permita este tipo de acercamientos a sociedades cazadoras-recolectoras prehistóricas

The association between a body shape index and cardiovascular risk in overweight and obese children and adolescents

A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2\u201318 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass % detected by bioelectrical impedance analysis) and obesity-related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity

Effects of a multidisciplinary weight loss intervention in overweight and obese children and adolescents: 11 years of experience

Aims To evaluate the effects of an outpatient multidisciplinary weight loss intervention in reducing body mass index (BMI) in children and adolescents suffering overweight and obesity, changes in A Body Shape Index (ABSI, waist circumference normalized to height and weight) and Hip Index (HI, normalized hip circumference) during treatment and correlation between the ABSI and HI with change in BMI z score. Methods We analyze anthropometric data from pediatric patients affected by overweight and obesity aged 2 to 18 years old who entered our multidisciplinary weight loss intervention, which included medical, psychological and nutritional sessions, from January 1st 2006 to December 31st 2016. Lifestyle modification counselling was delivered. Follow-up visits were planned every month for 3 months and subsequently every 2±4 months. BMI, ABSI, and HI were converted to z scores using age and sex specific population normals. Results 864 patients entered our intervention. 453 patients (208 males), mean age 11.2 ±3.1 years, 392 with obesity (86%, z-BMI 2.90 ±0.80 SD) and 61 patients with overweight (z-BMI 1.73±0.21 SD) attended at least 1 follow-up visit. The mean number of visits was 3.5 (± 1.8 SD) in overweight subjects and 3.9 (±2.2 SD) in ones with obesity. At the last attended follow- up visit (at 16 ± 12 months SD) we observed a reduction in mean z-BMI in patients with obesity (to 2.52 ±0.71 SD) and patients with overweight (to 1.46 ±0.5 SD). Most patients (80.8%) reduced their BMI z scores. Mean ABSI and HI z scores showed no significant change. 78/392 patients (19.8%) recovered from obese to overweight, 5/392 (1.2%) from obese to normal weight. The recovery rate from overweight to normal weight was 13.1%. Ina multivariate model, initial BMI z score and number of follow-up visits were significant predictors of weight change, while age, sex, ABSI, and HI were not significant predictors. Conclusions Patients affected by overweight and obesity involved in a multidisciplinary weight loss intervention reduced their mean BMI z score, while ABSI and HI were stable. Weight loss was not predicted by initial ABSI or HI. More visits predict more weight loss, but dropout rates are high. The great majority of patients leave the weight management program before having normalized their BMI