Do circum-Antarctic species exist in peracarid Amphipoda? A case study in the genus Epimeria Costa, 1851 (Crustacea, Peracarida, Epimeriidae)

The amphipod genus Epimeria is species rich in the Southern Ocean and at present eight of its 19 species are reported with circum-Antarctic distributions. For the first time, specimens of epimeriid species from the Antarctic Peninsula, the Weddell Sea and the Ross Sea were analysed using partial COI genes sequences and morphological characters. In total 37 specimens of 14 species of Epimeria and two species of Epimeriella were analysed and the resulting molecular topology checked by critically reviewing taxonomic characters. The genus Epimeriella, genetically grouping within Epimeria is synonymised with the genus Epimeria. Sequences distances between populations of the nominal species Epimeria robusta from the Weddell and Ross Sea led to detailed morphological investigations, resulting in the description of Epimeria robustoides sp. n. from the Weddell Sea. Epimeria robusta Barnard, 1930 from the Ross Sea is redescribed. Sequences of a damaged Epimeria specimen of a species new to science from the lower continental shelf of the eastern Weddell Sea were included. Based on the current study, the hypothesis of circum-Antarctic species' distributions in brooding amphipods proved to be unlikely

Multiple breaking patterns in the Brout-Englert-Higgs effect beyond perturbation theory

In many BSM theories, especially GUTs, introducing a Brout-Englert-Higgs effect allows for multiple breaking patterns of the gauge symmetry. The possibility to select a particular pattern is usually decisive for the phenomenological viability of a theory. Beyond perturbation theory it is necessary to replace the Brout-Englert-Higgs effect by a manifestly gauge-invariant description. We study the simplest case with multiple breaking patterns, an $\textrm{SU}(3)$ Yang-Mills theory coupled to a single scalar `Higgs' field in the adjoint representation, on the lattice. We find that only one pattern remains at fixed parameters and gauge-fixing strategy, and that the associated quantum effective potential emerges from a non-trivial interplay of many aspects.Comment: 32 pages, 22 figures (with several subfigures), 1 tabl

Survival in Soviet Gulags: A Secondary Analysis

One of the most common book series on the subject of Soviet Gulags is Evgenia Ginzburg’s “Journey into the Whirlwind” and “Within the Whirlwind.” This paper will use secondary analysis from anthology works with stories similar to Ginzburg\u27s in combination with the works of several other authors like Anne Applebaum (2011) and Geith and Jolluck (2011). It shall also examine extensively Raphaël Lemkin’s definition of genocide and how it fits to what happened in the Gulags. It shall be argued why certain situations that occurred within the Gulags fit this definition. It will also explore the intimate details and lives of the Repressed. It will clarify vividly some of the social psychological and life experiences they faced in the Gulags and what coping mechanisms they used to survive them

Just checking it out? Motivations for and behavioral associations with visiting "Slutpages" in the United States and Australia

“Slutpages” are a pernicious form of online image-based evaluative voyeurism (OIBEV), whereby (sexualized) images of women are posted on webpages for (predominantly) male groups to rate and comment. Despite media and public concern, OIBEV sites have garnered limited empirical study. This paper presents the first analysis of OIBEV site visitation motivations across United States and Australian samples. Participants comprised a convenience sample of 1148 young adults aged 18 to 29 years (M = 22.54, SD = 2.50); 53.0% women, 47.0% men; 54% residing in the U.S. and 46% in Australia. Respondents completed an online questionnaire. Overall, 23% of United States and 16% of Australian respondents had visited OIBEV sites. OIBEV site visitation was uniquely associated with gender and country (with men and United States being more likely to visit OIBEV sites), requesting and disseminating sexts and having one’s own image shared. Cyberbullying perpetration was associated with reduced odds of OIBEV site visitation. Motivations differed by gender, with men (80%) being most likely to visit sites to “check them out” while women were equally likely to check it out (41%) or to see if they were depicted (36%). For men, unique predictors of OIBEV site visitation were having requested, disseminated and received disseminated sexts, lower levels of anxiety and reduced likelihood of cyberbullying perpetration. For women, OIBEV site visitation was uniquely associated with being a United States resident, sext dissemination victimization, receipt of disseminated sexts, higher levels of anxiety but reduced stress. Our findings confirm that OIBEV sites represent a highly gendered form of online image-based sexual abuse, and may have important mental health implications, given the associations with increased anxiety. Our results support the need for “slutpage” education for adolescents and young adults to address social and peer norms that encourage and support non-consensual use of intimate images

Institutionalizing Community-Based Learning and Research: The Case for External Networks

Conversations continue as to whether and how community-based learning and research (CBLR) can be most effectively integrated into the mission and practice of institutions of higher education (IHEs). In 2005, eight District of Columbia- (DC-) area universities affiliated with the Community Research and Learning (CoRAL) Network engaged in a planning and evaluation exercise, applying a “rapid assessment” method to gauge baseline levels of CBLR institutionalization on each campus, envisioning progress in key areas, and proposing ways in which the CoRAL Network could achieve institutionalization goals. Aggregate analysis of the assessment data suggests several areas of similarity across extremely diverse university settings. Principle among the areas of similarity is the clearly articulated need for a network structure, external to any given university, to play a strategic role in enabling CBLR institutionalization goals

The association between green space and cause-specific mortality in urban New Zealand: an ecological analysis of green space utility

<b>Background:</b> There is mounting international evidence that exposure to green environments is associated with health benefits, including lower mortality rates. Consequently, it has been suggested that the uneven distribution of such environments may contribute to health inequalities. Possible causative mechanisms behind the green space and health relationship include the provision of physical activity opportunities, facilitation of social contact and the restorative effects of nature. In the New Zealand context we investigated whether there was a socioeconomic gradient in green space exposure and whether green space exposure was associated with cause-specific mortality (cardiovascular disease and lung cancer). We subsequently asked what is the mechanism(s) by which green space availability may influence mortality outcomes, by contrasting health associations for different types of green space. <b>Methods:</b> This was an observational study on a population of 1,546,405 living in 1009 small urban areas in New Zealand. A neighbourhood-level classification was developed to distinguish between usable (i.e., visitable) and non-usable green space (i.e., visible but not visitable) in the urban areas. Negative binomial regression models were fitted to examine the association between quartiles of area-level green space availability and risk of mortality from cardiovascular disease (n = 9,484; 1996 - 2005) and from lung cancer (n = 2,603; 1996 - 2005), after control for age, sex, socio-economic deprivation, smoking, air pollution and population density. <b>Results:</b> Deprived neighbourhoods were relatively disadvantaged in total green space availability (11% less total green space for a one standard deviation increase in NZDep2001 deprivation score, p < 0.001), but had marginally more usable green space (2% more for a one standard deviation increase in deprivation score, p = 0.002). No significant associations between usable or total green space and mortality were observed after adjustment for confounders. <b>Conclusion</b> Contrary to expectations we found no evidence that green space influenced cardiovascular disease mortality in New Zealand, suggesting that green space and health relationships may vary according to national, societal or environmental context. Hence we were unable to infer the mechanism in the relationship. Our inability to adjust for individual-level factors with a significant influence on cardiovascular disease and lung cancer mortality risk (e.g., diet and alcohol consumption) will have limited the ability of the analyses to detect green space effects, if present. Additionally, green space variation may have lesser relevance for health in New Zealand because green space is generally more abundant and there is less social and spatial variation in its availability than found in other contexts

Life Stories Between the Former Soviet Union and the United States

This paper examines the change from the Soviet Period to Transition Period, as reported through the experiences of those who grew up there, as well as from American tourists who have traveled there. Five semi-structured interviews were been conducted. They were transcribed and analyzed inductively to understand (a) differences in life experiences across cultures, (b) how change in government effects a person\u27s life story and (c) the importance of social traditions. Findings focus on the transformation of economic conditions from the point before the transition to independent republics after the transition. Findings focus on technological expansion and traditions and customs surrounding alcohol consumption

Migratory zooplankton excreta and its influence on prokaryotic communities

© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Maas, A. E., Liu, S., Bolanos, L. M., Widner, B., Parsons, R., Kujawinski, E. B., Blanco-Bercial, L., & Carlson, C. A. Migratory zooplankton excreta and its influence on prokaryotic communities. Frontiers in Marine Science, 7, (2020): 573268, doi:10.3389/fmars.2020.573268.Particulate organic matter (POM) (fecal pellets) from zooplankton has been demonstrated to be an important nutrient source for the pelagic prokaryotic community. Significantly less is known about the chemical composition of the dissolved organic matter (DOM) produced by these eukaryotes and its influence on pelagic ecosystem structure. Zooplankton migrators, which daily transport surface-derived compounds to depth, may act as important vectors of limiting nutrients for mesopelagic microbial communities. In this role, zooplankton may increase the DOM remineralization rate by heterotrophic prokaryotes through the creation of nutrient rich “hot spots” that could potentially increase niche diversity. To explore these interactions, we collected the migratory copepod Pleuromamma xiphias from the northwestern Sargasso Sea and sampled its excreta after 12–16 h of incubation. We measured bulk dissolved organic carbon (DOC), dissolved free amino acids (DFAA) via high performance liquid chromatography and dissolved targeted metabolites via quantitative mass spectrometry (UPLC-ESI-MSMS) to quantify organic zooplankton excreta production and characterize its composition. We observed production of labile DOM, including amino acids, vitamins, and nucleosides. Additionally, we harvested a portion of the excreta and subsequently used it as the growth medium for mesopelagic (200 m) bacterioplankton dilution cultures. In zooplankton excreta treatments we observed a four-fold increase in bacterioplankton cell densities that reached stationary growth phase after five days of dark incubation. Analyses of 16S rRNA gene amplicons suggested a shift from oligotrophs typical of open ocean and mesopelagic prokaryotic communities to more copiotrophic bacterial lineages in the presence of zooplankton excreta. These results support the hypothesis that zooplankton and prokaryotes are engaged in complex and indirect ecological interactions, broadening our understanding of the microbial loop.Funding for this research was provided by Simons Foundation International as part of the BIOS-SCOPE project to AM, LB-B, CC, and EK

Prehospital Management of Traumatic Brain Injury across Europe: A CENTER-TBI Study.

BACKGROUND: Prehospital care for traumatic brain injury (TBI) is important to prevent secondary brain injury. We aim to compare prehospital care systems within Europe and investigate the association of system characteristics with the stability of patients at hospital arrival. METHODS: We studied TBI patients who were transported to CENTER-TBI centers, a pan-European, prospective TBI cohort study, by emergency medical services between 2014 and 2017. The association of demographic factors, injury severity, situational factors, and interventions associated with on-scene time was assessed using linear regression. We used mixed effects models to investigate the case mix adjusted variation between countries in prehospital times and interventions. The case mix adjusted impact of on-scene time and interventions on hypoxia (oxygen saturation <90%) and hypotension (systolic blood pressure <100mmHg) at hospital arrival was analyzed with logistic regression. RESULTS: Among 3878 patients, the greatest driver of longer on-scene time was intubation (+8.3 min, 95% CI: 5.6-11.1). Secondary referral was associated with shorter on-scene time (-5.0 min 95% CI: -6.2- -3.8). Between countries, there was a large variation in response (range: 12-25 min), on-scene (range: 16-36 min) and travel time (range: 15-32 min) and in prehospital interventions. These variations were not explained by patient factors such as conscious level or severity of injury (expected OR between countries: 1.8 for intubation, 1.8 for IV fluids, 2.0 for helicopter). On-scene time was not associated with the regional EMS policy (p= 0.58). Hypotension and/or hypoxia were seen in 180 (6%) and 97 (3%) patients in the overall cohort and in 13% and 7% of patients with severe TBI (GCS <8). The largest association with secondary insults at hospital arrival was with major extracranial injury: the OR was 3.6 (95% CI: 2.6-5.0) for hypotension and 4.4 (95% CI: 2.9-6.7) for hypoxia. DISCUSSION: Hypoxia and hypotension continue to occur in patients who suffer a TBI, and remain relatively common in severe TBI. Substantial variation in prehospital care exists for patients after TBI in Europe, which is only partially explained by patient factors

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.

Despite major progress in defining the genetic basis of Mendelian disorders, the molecular etiology of many cases remains unknown. Patients with these undiagnosed disorders often have complex presentations and require treatment by multiple health care specialists. Here, we describe an integrated clinical diagnostic and research program using whole-exome and whole-genome sequencing (WES/WGS) for Mendelian disease gene discovery. This program employs specific case ascertainment parameters, a WES/WGS computational analysis pipeline that is optimized for Mendelian disease gene discovery with variant callers tuned to specific inheritance modes, an interdisciplinary crowdsourcing strategy for genomic sequence analysis, matchmaking for additional cases, and integration of the findings regarding gene causality with the clinical management plan. The interdisciplinary gene discovery team includes clinical, computational, and experimental biomedical specialists who interact to identify the genetic etiology of the disease, and when so warranted, to devise improved or novel treatments for affected patients. This program effectively integrates the clinical and research missions of an academic medical center and affords both diagnostic and therapeutic options for patients suffering from genetic disease. It may therefore be germane to other academic medical institutions engaged in implementing genomic medicine programs