3,939 research outputs found
Time-course of vascular adaptations during 8 weeks of exercise training in subjects with type 2 diabetes and middle-aged controls
CONCLUSION: Training leads to rapid improvement in brachial artery vascular function in diabetes patients and controls. In contrast to previous observations in healthy young subjects, the increase in function was preserved after 8 weeks of training in middle-aged diabetes patients and controls, suggesting a different time-course in vascular adaptations in subjects with endothelial dysfunction
A simple approach to counterterms in N=8 supergravity
We present a simple systematic method to study candidate counterterms in N=8
supergravity. Complicated details of the counterterm operators are avoided
because we work with the on-shell matrix elements they produce. All n-point
matrix elements of an independent SUSY invariant operator of the form D^{2k}
R^n +... must be local and satisfy SUSY Ward identities. These are strong
constraints, and we test directly whether or not matrix elements with these
properties can be constructed. If not, then the operator does not have a
supersymmetrization, and it is excluded as a potential counterterm. For n>4, we
find that R^n, D^2 R^n, D^4 R^n, and D^6 R^n are excluded as counterterms of
MHV amplitudes, while only R^n and D^2 R^n are excluded at the NMHV level. As a
consequence, for loop order L<7, there are no independent D^{2k}R^n
counterterms with n>4. If an operator is not ruled out, our method constructs
an explicit superamplitude for its matrix elements. This is done for the 7-loop
D^4 R^6 operator at the NMHV level and in other cases. We also initiate the
study of counterterms without leading pure-graviton matrix elements, which can
occur beyond the MHV level. The landscape of excluded/allowed candidate
counterterms is summarized in a colorful chart.Comment: 25 pages, 1 figure, published versio
R^4 counterterm and E7(7) symmetry in maximal supergravity
The coefficient of a potential R^4 counterterm in N=8 supergravity has been
shown previously to vanish in an explicit three-loop calculation. The R^4 term
respects N=8 supersymmetry; hence this result poses the question of whether
another symmetry could be responsible for the cancellation of the three-loop
divergence. In this article we investigate possible restrictions from the coset
symmetry E7(7)/SU(8), exploring the limits as a single scalar becomes soft, as
well as a double-soft scalar limit relation derived recently by Arkani-Hamed et
al. We implement these relations for the matrix elements of the R^4 term that
occurs in the low-energy expansion of closed-string tree-level amplitudes. We
find that the matrix elements of R^4 that we investigated all obey the
double-soft scalar limit relation, including certain
non-maximally-helicity-violating six-point amplitudes. However, the single-soft
limit does not vanish for this latter set of amplitudes, which suggests that
the E7(7) symmetry is broken by the R^4 term.Comment: 33 pages, typos corrected, published versio
The views of older women towards mammographic screening: a qualitative and quantitative study
Purpose: Mammographic screening has improved breast cancer survival in the screened age group. This improved survival has not been seen in older women (>70 years) where screening uptake is low. This study explores the views, knowledge and attitudes of older women towards screening.
Methods: Women (>70) were interviewed about breast screening. Interview findings informed the development of a questionnaire which was sent to 1000 women (>70) to quantify their views regarding screening.
Results: Twenty-six women were interviewed and a questionnaire designed. The questionnaire response rate was 48.3% (479/992). Over half (52.9%, 241/456) of respondents were unaware they could request mammography by voluntary self-referral and were unaware of how to arrange this. Most (81.5% 383/470) had not attended breast screening since turning 70. Most (75.6%, 343/454) felt screening was beneficial and would attend if invited. Most, (90.1%, 412/457) felt screening should be offered to all women regardless of age or health.
Conclusions: There is a lack of knowledge about screening in older women. The majority felt that invitation to screening should be extended to the older age group regardless of age or health. The current under-utilised system of voluntary self referral is not supported by older women
Minor Physical Anomalies in Patients with Schizophrenia, Unaffected First-Degree Relatives, and Healthy Controls: A Meta-Analysis
Background: Minor physical anomalies (MPAs) have been found to be more prevalent in schizophrenia than control participants in numerous studies and may index a potential endophenotype for schizophrenia.</p
Riparian ecotones and spatial variation of fish assemblages in Portuguese lowland streams
The first results of a long-term study on the role of riparian ecotones on the population and community
dynamics of Iberian stream fish are presented and discussed . Riparian and macrophyte cover, bank
slope and depth were among the most important variables affecting fish distribution . In general small
fish favoured shallow areas with high macrophyte cover, whereas large fish dominated in deep areas with
a high riparian cover . Slight spatial changes in terrestrial prey use were found suggesting a minor role
for this resource during autumn . Finally, no significant spatial differences were found for linear growth,
although some differences were obtained for the condition facto
Supermembrane interaction with dynamical D=4 N=1 supergravity. Superfield Lagrangian description and spacetime equations of motion
We obtain the complete set of equations of motion for the interacting system
of supermembrane and dynamical D=4 N = 1 supergravity by varying its complete
superfield action and writing the resulting superfield equations in the special
gauge where the supermembrane Goldstone field is set to zero. We solve the
equations for auxiliary fields and discuss the effect of dynamical generation
of cosmological constant in the Einstein equation of interacting system and its
renormalization due to some regular contributions from supermembrane. These two
effects (discussed in late 70th and 80th, in the bosonic perspective and in the
supergravity literature) result in that, generically, the cosmological constant
has different values in the branches of the spacetime separated by the
supermembrane worldvolume.Comment: 23 pages, no figures. V2 two references added, 24 page
Trace-gas metabolic versatility of the facultative methanotroph Methylocella silvestris
The climate-active gas methane is generated both by biological processes and by thermogenic decomposition of fossil organic material, which forms methane and short-chain alkanes, principally ethane, propane and butane1, 2. In addition to natural sources, environments are exposed to anthropogenic inputs of all these gases from oil and gas extraction and distribution. The gases provide carbon and/or energy for a diverse range of microorganisms that can metabolize them in both anoxic3 and oxic zones. Aerobic methanotrophs, which can assimilate methane, have been considered to be entirely distinct from utilizers of short-chain alkanes, and studies of environments exposed to mixtures of methane and multi-carbon alkanes have assumed that disparate groups of microorganisms are responsible for the metabolism of these gases. Here we describe the mechanism by which a single bacterial strain, Methylocella silvestris, can use methane or propane as a carbon and energy source, documenting a methanotroph that can utilize a short-chain alkane as an alternative to methane. Furthermore, during growth on a mixture of these gases, efficient consumption of both gases occurred at the same time. Two soluble di-iron centre monooxygenase (SDIMO) gene clusters were identified and were found to be differentially expressed during bacterial growth on these gases, although both were required for efficient propane utilization. This report of a methanotroph expressing an additional SDIMO that seems to be uniquely involved in short-chain alkane metabolism suggests that such metabolic flexibility may be important in many environments where methane and short-chain alkanes co-occur
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