44,315 research outputs found
Quantum walks on two kinds of two-dimensional models
In this paper, we numerically study quantum walks on two kinds of
two-dimensional graphs: cylindrical strip and Mobius strip. The two kinds of
graphs are typical two-dimensional topological graph. We study the crossing
property of quantum walks on these two models. Also, we study its dependence on
the initial state, size of the model. At the same time, we compare the quantum
walk and classical walk on these two models to discuss the difference of
quantum walk and classical walk
Impact of Driving Cycles on Greenhouse Gas (GHG) Emissions, Global Warming Potential (GWP) and Fuel Economy for SI Car Real World Driving
The transport sector is one of the major contributors to greenhouse gas emissions. This study investigated three greenhouse gases emitted from road transport: CO2, N2O and CH4 emissions as a function of engine warm up and driving cycles. Five different urban driving cycles were developed and used including free flow driving and congested driving. An in-vehicle FTIR (Fourier Transform Inferred) emission measurement system was installed on a EURO2 emission compliant SI (Spark Ignition) car for emissions measurement at a rate of 0.5 HZ under real world urban driving conditions. This emission measurement system was calibrated on a standard CVS (Constant Volume Sampling) measurement system and showed excellent agreement on CO2 measurement with CVS results. The N2O and CH4 measurement was calibrated using calibration gas in lab. A MAX710 real time in-vehicle fuel consumption measurement system was installed in the test vehicle and real time fuel consumption was then obtained. The temperatures across the TWC (Three Way Catalyst) and engine out exhaust gas lambda were measured. The GHG (greenhouse gas) mass emissions and consequent GWP (Global Warming Potential) for different urban diving conditions were analyzed and presented. The results provided a better understanding of traffic related greenhouse gas emission profile in urban area and will contribute to the control of climate change
Generic Quantum Walks with Memory
Quantum walks with memory(QWM) are a type of modified quantum walks that
record the walker's latest path. As we know, only two kinds of QWM are
presented up to now. It is desired to design more QWM for research, so that we
can explore the potential of QWM. In this work, through presenting the
one-to-one correspondence between QWM on a regular graph and quantum walks
without memory(QWoM) on line digraph of the regular graph, we construct a
generic model of QWM on regular graphs. This construction gives a general
scheme for building all possible standard QWM on regular graphs and makes it
possible to study properties of different kinds of QWM. Here, by taking the
simplest example which is QWM with 1 memory on the line, we analyze some
properties of QWM, such as variance, occupancy rate and localization.Comment: 8 pages, 5 figure
Effect of therapeutic play on pre- and post-operative anxiety and emotional responses in Hong Kong Chinese children: a randomised controlled trial
published_or_final_versio
Aquaporin-4 and brain edema.
Aquaporin-4 (AQP4) is a water-channel protein expressed strongly in the brain, predominantly in astrocyte foot processes at the borders between the brain parenchyma and major fluid compartments, including cerebrospinal fluid (CSF) and blood. This distribution suggests that AQP4 controls water fluxes into and out of the brain parenchyma. Experiments using AQP4-null mice provide strong evidence for AQP4 involvement in cerebral water balance. AQP4-null mice are protected from cellular (cytotoxic) brain edema produced by water intoxication, brain ischemia, or meningitis. However, AQP4 deletion aggravates vasogenic (fluid leak) brain edema produced by tumor, cortical freeze, intraparenchymal fluid infusion, or brain abscess. In cytotoxic edema, AQP4 deletion slows the rate of water entry into brain, whereas in vasogenic edema, AQP4 deletion reduces the rate of water outflow from brain parenchyma. AQP4 deletion also worsens obstructive hydrocephalus. Recently, AQP4 was also found to play a major role in processes unrelated to brain edema, including astrocyte migration and neuronal excitability. These findings suggest that modulation of AQP4 expression or function may be beneficial in several cerebral disorders, including hyponatremic brain edema, hydrocephalus, stroke, tumor, infection, epilepsy, and traumatic brain injury
A second Cretaceous ornithuromorph bird from the Changma Basin, Gansu Province, Northwestern China
Finely-bedded lacustrine deposits of the Aptian (Lower Cretaceous) Xiagou Formation exposed in the Changma Basin of Gansu Province, northwestern China, have yielded numerous fossil vertebrate remains, including approximately 100 avian specimens. Though the majority of these birds appear referable to the ornithuromorph Gansus yumenensis, a number of enantiornithine fossils have also been recovered. Here we report on a specimen consisting of a complete, three-dimensionally preserved sternum, furcula, and sternal ribs that represents a second ornithuromorph taxon from the Xiagou Formation at Changma. The fossil exhibits morphologies that distinguish it from all previously-known Xiagou birds and demonstrate that it represents a derived non-ornithurine member of Ornithuromorpha. Though it is morphologically distinct from the equivalent elements of all other described ornithuromorphs, the material is too incomplete to justify the erection of a new taxon. Nonetheless, it increases the taxonomic diversity of the Xiagou avifauna, thereby expanding our knowledge of Early Cretaceous avian diversity and evolution
Validity and reliability of the Chinese critical thinking disposition inventory
2004-2005 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Mechanisms of enhanced heterogeneous nucleation during solidification in binary Al-Mg alloys
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 ElsevierThe mechanisms involved in the grain refinement of Al–Mg alloys through varying the Mg content and applying intensive melt shearing were investigated. It was found that the oxide formed in Al–Mg alloys under normal melting conditions is MgAl2O4, which displays an equiaxed and faceted morphology with {1 1 1} planes exposed as its natural surfaces. Depending on the Mg content, MgAl2O4 particles exist either as oxide films in dilute Al–Mg alloys (Mg 1 wt.%). Such MgAl2O4 particles can act as potent sites for nucleation of α-Al grains, which is evidenced by the well-defined cube-on-cube orientation relationship between MgAl2O4 and α-Al. Enhanced heterogeneous nucleation in Al–Mg alloys can be attributed to the high potency of MgAl2O4 particles with a lattice misfit of 1.4% and the increased number density of MgAl2O4 particles due to either natural dispersion by the increased Mg content or forced dispersion through intensive melt shearing. It was also found that intensive melt shearing leads to significant grain refinement of dilute Al–Mg alloys by effective dispersion of the MgAl2O4 particles entrapped in oxide films, but it has marginal effect on the grain refinement of concentrated Al–Mg alloys, where MgAl2O4 particles have been naturally dispersed into individual particles by the increased Mg content.This study is funded from the EPSRC Grant EP/H026177/1
Probing the formation of intermediate- to high-mass stars in protoclusters II. Comparison between millimeter interferometric observations of NGC 2264-C and SPH simulations of a collapsing clump
The earliest phases of massive star formation in clusters are still poorly
understood. Here, we test the hypothesis for high-mass star formation proposed
in our earlier paper (Peretto et al. 2006). In order to confirm the physical
validity of this hypothesis, we carried out IRAM Plateau de Bure interferometer
observations of NGC 2264-C and performed SPH numerical simulations of the
collapse of a Jeans-unstable, prolate dense clump. Our Plateau de Bure
observations reveal the presence of a new compact source (C-MM13) located only
\~ 10000 AU away, but separated by ~ 1.1 km/s in (projected) velocity, from the
most massive Class 0 object (C-MM3) lying at the very center of NGC 2264-C.
Detailed comparison with our numerical SPH simulations supports the view that
NGC 2264-C is an elongated cluster-forming clump in the process of collapsing
and fragmenting along its long axis, leading to a strong dynamical interaction
and possible protostar merger in the central region of the clump. The present
study also sets several quantitative constraints on the initial conditions of
large-scale collapse in NGC 2264-C. Our hydrodynamic simulations indicate that
the observed velocity pattern characterizes an early phase of protocluster
collapse which survives for an only short period of time (i.e., < 10^5 yr). To
provide a good match to the observations the simulations require an initial
ratio of turbulent to gravitational energy of only ~ 5 %, which strongly
suggests that the NGC 2264-C clump is structured primarily by gravity rather
than turbulence. The required "cold'' initial conditions may result from rapid
compression by an external trigger.Comment: 15 pages, 8 figures, accepted for publication in A&
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors.
The production of recombinant proteins such as the fibroblast growth factors (FGFs) is the key to establishing their function in cell communication. The production of recombinant FGFs in E. coli is limited, however, due to expression and solubility problems. HaloTag has been used as a fusion protein to introduce a genetically-encoded means for chemical conjugation of probes. We have expressed 11 FGF proteins with an N-terminal HaloTag, followed by a tobacco etch virus (TEV) protease cleavage site to allow release of the FGF protein. These were purified by heparin-affinity chromatography, and in some instances by further ion-exchange chromatography. It was found that HaloTag did not adversely affect the expression of FGF1 and FGF10, both of which expressed well as soluble proteins. The N-terminal HaloTag fusion was found to enhance the expression and yield of FGF2, FGF3 and FGF7. Moreover, whereas FGF6, FGF8, FGF16, FGF17, FGF20 and FGF22 were only expressed as insoluble proteins, their N-terminal HaloTag fusion counterparts (Halo-FGFs) were soluble, and could be successfully purified. However, cleavage of Halo-FGF6, -FGF8 and -FGF22 with TEV resulted in aggregation of the FGF protein. Measurement of phosphorylation of p42/44 mitogen-activated protein kinase and of cell growth demonstrated that the HaloTag fusion proteins were biologically active. Thus, HaloTag provides a means to enhance the expression of soluble recombinant proteins, in addition to providing a chemical genetics route for covalent tagging of proteins
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