Marginal Bone Loss and Pink Esthetic Evaluation of Narrow-Diameter Dental Implants for Single Crowns: 1-Year Prospective Clinical Study

Purpose: The aims of this study were: (1) to quantify the marginal bone loss (MBL) of 3.3-mm narrow-diameter, bone-level, titanium-zirconia (Ti-Zr) implants with two different surfaces in single restorations after a 1-year follow-up; (2) to analyze the combinations of different variables that may influence MBL; and (3) to record the Pink Esthetic Score (PES) value and its correlation with MBL. Materials and Methods: This is a prospective longitudinal clinical study with a 1-year follow-up after crown placement. Two different implant surfaces (sandblasted acid-etched and modified sandblasted acid-etched) were used. All bone-level and bone level-tapered implants had a diameter of 3.3 mm. Different healing and prosthetic abutments were used. Clinical, radiographic, and photographic records were taken 6 months and 1 year after placement of the restorations, and the survival rate, MBL, PES, clinical parameters, and biologic and/or mechanical complications were assessed. The correlations between the variables and MBL were verified. Results: A total of 30 narrow-diameter implants were placed in 30 patients; 18 implants had a sandblasted acid-etched surface, and 12 implants had a modified sandblasted acid-etched surface. The measured MBL at 1 year after implant function had a mean value of-0.36 mm, ranging from 0 mm to-1.77 mm. There was no implant loss. A statistically significant relationship was observed between implant shape (design and length), implant placement level, healing abutment, prosthetic abutment size, gingival thickness, and MBL. The mean PES values recorded at the beginning and end of the study were 7.58 and 11.37, respectively. Conclusion: Narrow-diameter implants showed reduced MBL values, with the surrounding tissues remaining stable after 1 year of follow-up. The MBL did not show different values on two implant surfaces. MBL does not seem to influence esthetic outcome. Int.Oral Maxillofaciallmplants2022;37::515-524. doi: 10.11607/jomi.905

Asymmetric core combustion in neutron stars and a potential mechanism for gamma ray bursts

We study the transition of nuclear matter to strange quark matter (SQM) inside neutron stars (NSs). It is shown that the influence of the magnetic field expected to be present in NS interiors has a dramatic effect on the propagation of a laminar deflagration (widely studied so far), generating a strong acceleration of the flame in the polar direction. This results in a strong asymmetry in the geometry of the just formed core of hot SQM which resembles a cylinder orientated in the direction of the magnetic poles of the NS. This geometrical asymmetry gives rise to a bipolar emission of the thermal neutrino-antineutrino pairs produced in the process of SQM formation. The neutrino-antineutrino pairs annihilate into electron-positron pairs just above the polar caps of the NS giving rise to a relativistic fireball, thus providing a suitable form of energy transport and conversion to gamma emission that may be associated to short gamma ray bursts (GRBs).Comment: 2 figure

Comparison of Nasopharyngeal Samples for SARS‐CoV ‐2 Detection in a Paediatric Cohort

Aim: The diagnosis of coronavirus disease 2019 (COVID-19) depends on accurate and rapid testing. Choosing an appropriate sample may impact diagnosis. Naso-oropharyngeal swabs (NOS) are most frequently used, despite several limitations. Since studies suggest nasopharyngeal aspirate (NPA) as a superior alternative in children, we hypothesised collecting both nasopharyngeal swab and aspirate would improve our diagnostic accuracy. Methods: Observational, longitudinal, prospective study from 7 March to 7 May in a tertiary paediatric hospital in Lisbon. The objective was to compare the rate of detection of SARS-CoV-2 between NOS and NPA samples collected simultaneously. Results: A total of 438 samples collected from 85 patients with confirmed COVID-19. There were 47.7% overall positive specimens - 32% (70/219) positive NOS and 63.5% (139/219) positive NPA. The tests were 67.6% concordant (k = 0.45). 50.3% had positive NPA with negative NOS, while 1.3% had positive NOS with negative NPA. NPA proved to be more sensitive (98.6% with 95% confidence interval 91.2-99.9% vs. 49.6% with 95% confidence interval 41.1-58.2%, P < 0.001). Additionally, the difference between NPA and NOS positive samples was statistically significant across all population groups (age, health condition, clinical presentation, contact with COVID-19 patients or need for hospitalisation), meaning NPA is more sensitive overall. Conclusions: Nasopharyngeal aspirates had greater sensitivity than naso-oropharyngeal swabs in detecting SARS-CoV-2. Our results suggest paediatric patients would benefit from collecting nasopharyngeal aspirates in hospital settings, whenever feasible, to improve diagnosis of COVID-19.info:eu-repo/semantics/publishedVersio

A educação ambiental por meio do uso das metodologias ativas: um estudo de caso na cidade de Cabo frio (RJ)

oferta escassa nos serviços de saneamento básico, bem como a eliminação inadequada dos resíduos sólidos urbanos (RSU) são, historicamente, impasses que o Brasil enfrenta. O objetivo deste estudo é analisar e avaliar o processo ensino e aprendizagem de educando, em relação à abordagem das condições de oferta de saneamento básico e eliminação, de forma imprópria, dos RSU. O público-alvo é composto por 36 discentes: 21 mulheres e 14 homens matriculados no Curso Técnico de Hospedagem integrado ao Ensino Médio (CTHIEM) do Instituto Federal Fluminense, campus de Cabo Frio (IFF-CF). Utilizou-se como estratégia de ensino, o uso das metodologias ativas (MA), a fim de sensibilizar os participantes sobre os agravos ambientais. Investiu-se em uma abordagem pedagógica baseada em situações-problema, além de aplicar um questionário elaborado com 5 questões objetivas, formulado pelo aplicativo Quizizz, onde os participantes, após a experenciação obtiveram uma média de 93,33% de respostas corretas (DP: ±6,97; EP: ±2,95).info:eu-repo/semantics/publishedVersio

Proposta de um jogo digital para educação ambiental: saneamento básico para todos

O presente relatório apresenta um das atividades desenvolvidas pela primeira autora, no seu projeto de Doutoramento em Ciências da Informação, Especialidade em Sistemas, Tecnologias e Gestão da Informação, sob a orientação dos professores Doutor Luís Borges Gouveia e Doutora Maria Alzira Dinis, com título provisório: “As metodologias ativas como proposta de intervenção pedagógica em educação ambiental: um estudo de caso na cidade de Cabo Frio, RJ, Brasil”. O objetivo é identificar as perceções que os estudantes tiveram sobre os prejuízos causados ao meio ambiente e a saúde humana, bem como a importância dos serviços de saneamento básico por meio dos conteúdos apresentados no jogo digital: "Saneamento Básico para todos." Preliminarmente, foi feita uma avaliação do jogo por 10 estudantes, escolhidos de forma aleatória, que após jogarem sugeriram uma série de ajustes que foram efetuados junto ao desenvolvedor. Após essa fase, foi solicitado que os estudantes do Curso de Hospedagem Integrado ao Ensino Médio (CHIEM), do Instituto Federal Fluminense de Cabo Frio (IFF/CF), baixassem o jogo e após jogarem, deveriam responder a um questionário previamente elaborado, composto por 13 perguntas objetivas, aplicando a Escala Likert, e 3 perguntas subjetivas. Em termos de considerações finais, de acordo com as respostas dos educandos foi possível perceber que o jogo alerta sobre a importância da instalação da rede de saneamento básico para a cidade, portanto, 97,1% dos participantes responderam concordar com essa temática.info:eu-repo/semantics/publishedVersio

Jogos digitais educacionais como uma proposta de trabalho em educação ambiental

Pereira, R.; Gouveia, L. e Dinis, A. (2021). Jogos digitais educacionais como uma proposta de trabalho em Educação Ambiental. Seminário Doutoramento em Ciência da Informação, especialidade Sistemas, Tecnologias e Gestão da Informação (SITEGI). 16 de Julho. Universidade Fernando Pessoa. Porto.info:eu-repo/semantics/publishedVersio

Characterization of phenolic compounds in Helichrysum melaleucumby high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection

Helicrysum melaleucum is a medicinal plant traditionally used in the islands of the Macaronesia region for the treatment of respiratory diseases. In this work, the phenolic compounds of Helicrysum melaleucum plants collected in different geographical locations of Madeira Island and their morphological parts (total aerial parts, leaves, flowers and stems) were extracted and analyzed separately by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-DAD/ESI-MS(n)). A total of 68 compounds were characterized based mainly on their UV and mass spectra. These included derivatives of O-glycosylated flavonoids (flavonol and flavones type), quinic acid, caffeic acid, lignans and polyphenols. The flowers were found to be the morphological part with higher variety of phenolic compounds. The large differences in the phenolic composition of plants collected from different geographical locations allowed the identification of a few components, such as pinoresinol and methoxylated flavone derivatives, likely to be useful as geographical markers. Also, these results promote further comparison of the bioactivities of the different samples analyzed. This paper marks the first report on the chemical analysis of Helichrysum melaleucum species.info:eu-repo/semantics/publishedVersio

Influence of antimicrobial photodynamic therapy as an adjunctive to scaling and root planing on alveolar bone loss: A systematic review and meta-analysis of animal studies.

BACKGROUND: The study aimed to evaluate the effect of antimicrobial photodynamic therapy (aPDT) as adjunctive therapy to scaling and root planing in experimental periodontitis in rats, with or without systemic involvement, by means of histometric analysis of the furcation region. METHODS: Systematic search was done using PubMed/MEDLINE, SCOPUS, EMBASE and ProQuest databases. Quantitative analysis of alveolar bone loss, with subcategories for the experimental periods studied, was performed. The analysis was performed through the mean difference (MD), with 95% confidence intervals (CIs) and according to SYRCLE guidelines. RESULTS: Nine studies were considered eligible. A statistically favorable difference was observed for the use of aPDT in all periods studied in systemically healthy animals at 7 (P < 0.00001; MD: -0.71; 95% CI: [-0.85, -0.58]; I2: 90%), 15 (P < 0.00001; MD: -0.49; 95% CI: [-0.62, -0.37]; I2: 88%), and 30 (P < 0.00001; MD: -0.53; 95% CI: [-0.65, -0.41]; I2: 80%) days postoperatively. The difference was also observed for modified animals at 7 (P < 0.00001; MD: -1.03; 95% CI: [-1.43, -0.62]; I2: 97%), 15 (P < 0.00001; MD: -1.04; 95% CI: [-1.62, -0.46]; I2: 99%), and 30 (P < 0.00001; MD: -0.88; 95% CI: [-1.37, -0.39]; I2: 97%) days postoperatively. CONCLUSION: The adjunctive use of aPDT favored the reduction of alveolar bone loss in experimental periodontitis in rats, and this result was more evident in systemically compromised rats

Doença de Kawasaki: casuística do Hospital Fernando da Fonseca

Introdução: A doença de Kawasaki (DK) é a doença cardíaca adquirida mais importante da infância, em países desenvolvidos. Vinte por cento das crianças não tratadas desenvolvem doença das coronárias, sendo as complicações a nível cardiovascular que determinam a morbilidade e mortalidade da doença. Objectivo: Avaliar a epidemiologia, clínica e alterações laboratoriais e ecocardiográficas dos casos de DK diagnosticados no H. Fernando Fonseca e identificar os eventuais factores que possam influenciar o prognóstico da doença. População e Métodos: Estudo retrospectivo, Junho 1996 a Dezembro de 2003, das crianças internadas no Hospital Fernando Fonseca com Doença Kawasaki. O diagnóstico baseou-se na presença de febre associada a 4 dos 5 critérios clássicos ou 3 deles em associação com aneurismas coronários. Analisaram-se parâmetros demográficos, clínica, exames complementares, terapêutica e evolução. A análise estatística foi realizada em SPSS, utilizando os testes de Mann-whitney e Teste Exacto de Fisher. Resultados: Registaram-se 23 crianças com DK. A incidência foi de 8,2 por 100 000 crianças < 5 anos. A idade variou entre os 6 meses e os 5 anos (mediana - 20 meses) Vinte e uma (91 %) tinham < 5 anos, dos quais 13 tinham < 2 anos. Houve um predomínio do sexo masculino (74 %) e da raça caucasiana (83 %). Nove casos residiam na mesma área geográfica. Foi documentada patologia infecciosa concomitante em 10 (43%)crianças (Parvovirus, Chlamydia pneumoniae, Vírus sincicial respiratório, Enterovirus e Herpes vírus 6). Vinte crianças preenchiam os critérios de DK clássica. Em 22 crianças foi administrada terapêutica combinada com aspirina e imunoglobulina endovenosa, em média foi administrada ao 7.º dia de doença. Sete (30 %) crianças apresentaram envolvimento das artérias coronárias. A idade inferior a 2 anos foi significativa para a lesão coronária. O tempo médio de seguimento foi de 16 meses. Não se registou mortalidade e actualmente apenas uma criança mantém aneurisma. Conclusões: O risco de lesões cardíacas associou-se à idade inferior a 2 anos, como descrito em outras séries. A origem geográfica em comum e a presença de diversos agentes infecciosos, pode indiciar, a importância da causa infecciosa como desencadeadora do processo

Microalgae production in fresh market wastewater and its utilization as a protein substitute in formulated fish feed for oreochromis spp.

Rapid growing of human population has led to increasing demand of aquaculture production. Oreochromis niloticus or known as tilapia is one of the most globally cultured freshwater fish due to its great adaptation towards extreme environment. Besides, farming of tilapia not only involves small scales farming for local consumption but also larger scales for international market which contributes to a foreign currency earning. Extensive use of fishmeal as feed for fish and for other animals indirectly caused an increasing depletion of the natural resource and may consequently cause economic and environmental unstable. Microalgae biomass seems to be a promising feedstock in aquaculture industry. It can be used for many purposes such as live food for fish larvae and dried microalgae to substitute protein material in fish feed. The microalgae replacement in fish feed formulation as protein alternative seem potentially beneficial for long term aqua-business sustainability. The present chapter discussed the potential of microalgae as an alternative nutrition in fish feed formulations, specifically Tilapia