7,455 research outputs found

    Flavour Changing Neutral Currents, Weak-Scale Scalars and Rare Top Decays

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    We examine the decays tcγt\rightarrow c\gamma and cZ0c Z^0 in the Standard Model with an extra scalar doublet and no discrete symmetry preventing tree-level flavour changing neutral currents. The Yukawa couplings of the new scalars are assumed to be proportional to fermion masses, evading bounds on FCNC's from the light quark sector. These rare top decays may be visible at the SSC.Comment: (some wording changed, and several references added) 13 pages, 2 figures included, uses harvmac.tex and epsf.tex, UCSD/PTH 93-0

    Use of electrical resistance tomography (ERT) for the detection of biofilm disruption mediated by biosurfactants

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    © 2018 Institution of Chemical Engineers Inline measurement of biofilms could provide a valuable technology for water, food and bioprocessing industries to improve quality control and avoid contamination. This study presents the first use of electrical resistance tomography (ERT) to detect the removal of biofilms in a pipe. It also tests the effectiveness of sophorolipids and rhamnolipids for the disruption of Bacillus subtilis BBK006 biofilms in an industrial setting. Biofilms were grown on the inner side of a section of 1.5″ test pipe for 5 days using nutrient broth as the culture medium. After the medium was removed the test pipe was incorporated into a cleaning test circuit for the biofilm disruption experiment, where water, sophorolipids (0.4 g L−1) or rhamnolipids (0.4 g L−1) solutions were pumped through respectively for 30 min. ERT was used as an indirect evaluation of the film disruption progression. A cleaning parameter was identified based on zonal boundary averages which successfully measured the extent of biofilm removal

    Diffusive Release of Photosensitizing Agents (PS) from Novel PVA-Borate Semi-Solid Drug Carriers Through In Vitro Oral Streptococcus mutans Biofilm

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    Background: Streptococcus mutans, one of the agent of human dental caries, is particularly effective at forming biofilms on the hard tissues of the human oral cavity; the purpose of this study was to investigate and quantify the diffusional release of photosentising agents (PS): methylene blue (MB), toludine blue (TB), rose bengal (RB) and methyl orange (MO) from Polyvinyl alcohol (PVA)-borate semi-solid gels in the presence of in vitro oral Streptococcus mutans biofilm. Methods: S. mutans biofilm growths were ascertained to ensure proper dental plaque formation and were characterized using confocal microscopy. Release profiles for MB, TB, RB and MO-loaded PVA-borate semi-solids in the absence of biofilms were directly compared to their counterparts in the presence of S. mutans biofilms. In addition, their diffusion coefficients and resistances were determined. Results: The confocal imaging results showed that biofilms grown over a 5-day period had a generally uninterrupted film of colonies occupying the entire surface area of growth surface of a nylon mesh support with approximately 60 µm biofilm size. The overall diffusion resistance of all PVA-borate semi-solids in the presence of S. mutans biofilms was about 1.2 times lower than the diffusion resistance for PVAborate semi-solids in the absence of biofilms. The diffusion resistances for all studied PS, indicate that electrostatic forces and molecular size play an important part in controlled and sustained drug release from PVA-borate semi-solids. Conclusions: PVA-borate semi-solids as novel PSs carriers might offer an innovative delivery system in the treatment against Streptococcus mutans

    Supersymmetric Model of Muon Anomalous Magnetic Moment and Neutrino Masses

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    We propose the novel lepton-number relationship Lτ=Le+LμL_\tau = L_e + L_\mu, which is uniquely realized by the interaction (ν^eμ^e^ν^μ)τ^c(\hat \nu_e \hat \mu - \hat e \hat \nu_\mu) \hat \tau^c in supersymmetry and may account for a possibly large muon anomalous magnetic moment. Neutrino masses (with bimaximal mixing) may be generated from the spontaneous and soft breaking of this lepton symmetry.Comment: 10 pages, including 2 figure

    Influence of microbial adherence on corrosion of UNS 1008 carbon steel and hybrid nano-structured coatings

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    Microbiologically induced corrosion (MIC) causes the degradation of coatings and it can be attributed to either direct or indirect microbial metabolic activity. In this study, we report the ability of sulphate reducing microorganisms (SRM) and marine strain bacteria to attach onto UNS1008 carbon steel, and zinc rich epoxy coatings with a content of carbon nanotubes (CNTs) respectively. In aerobic conditions the outer layer presents a micro-crack appearance and many semisphere products, attributed to spore formation. In anaerobic conditions, evidence of iron sulphide surrounded by a mixture of sulphur-containing extracellular polymer substance was observed by SEM images and EDS analysis. The presence of hybrid coatings (Zn rich epoxy with CNT content) affected the level of microbial adherence and the concentration of corrosion products (Fe2O3, Fe(OH)2, FeS); the cell attachment was lower when the steel surface was coated with Zn/CNTs

    Influence of microbial adherence on corrosion of UNS 1008 carbon steel and hybrid nano-structured coatings

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    Microbiologically induced corrosion (MIC) causes the degradation of coatings and it can be attributed to either direct or indirect microbial metabolic activity. In this study, we report the ability of sulphate reducing microorganisms (SRM) and marine strain bacteria to attach onto UNS1008 carbon steel, and zinc rich epoxy coatings with a content of carbon nanotubes (CNTs) respectively. In aerobic conditions the outer layer presents a micro-crack appearance and many semisphere products, attributed to spore formation. In anaerobic conditions, evidence of iron sulphide surrounded by a mixture of sulphur-containing extracellular polymer substance was observed by SEM images and EDS analysis. The presence of hybrid coatings (Zn rich epoxy with CNT content) affected the level of microbial adherence and the concentration of corrosion products (Fe2O3, Fe(OH)2, FeS); the cell attachment was lower when the steel surface was coated with Zn/CNTs

    Relaxing b\to s\gamma Constraints on the Supersymmetric Particle Mass Spectrum

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    We consider the radiative decay b \to s \gamma in a supersymmetric extension of the standard model of particle interactions, where the bb-quark mass is entirely radiative in origin. This is accomplished by the presence of nonholomorphic soft supersymmetry breaking terms in the Lagrangian. As a result, the contributions to the b \to s \gamma amplitude from the charged Higgs boson and the charginos/neutralinos are suppressed by 1/\tan^2\beta and {\cal O}(\alpha/\alpha_s) respectively, allowing these particles to be lighter than in the usual supersymmetric model. Their radiatively generated couplings differ from the usual tree-level ones and change the collider phenomenology drastically. We also study how this scenario may be embedded into a larger framework, such as supersymmetric SU(5) grand unification.Comment: references added, version to be published in PL

    Enhancement of Radiatively Induced Magnetic Moment Form-Factors of Muon: an Effective Lagrangian Approach

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    Using an effective lagrangian approach, we identify a class of models in which the loop-induced magnetic moment form-factors of muon are enhanced by possibly large factors (\Lambda^2_F/\Lambda^2)(m_\tau/m_\mu)\ln(m_\tau^2/\Lambda^2) or (\Lambda^2_F/\Lambda^2)\ln(m_\mu^2/\Lambda^2), where \Lambda is the scale of new physics and \Lambda_F is the Fermi scale. These follow from left- and right-chirality mixing dimension-8 operators which for relatively small \Lambda, as required to explain the new (g_\mu-2) measurement, dominate over dimension-6 operators. Thus significant enhancement of new physics contributions to (g_\mu-2) and, in the presence of intergenerational couplings, also to the \mu\to e\gamma decay rate is possible. We discuss the compatibility of the (g_\mu-2) and \mu\to e\gamma experimental data in this case and comment on the enhancement of the electron anomalous magnetic moment. An explicit model is presented to illustrate the general results.Comment: Discussion on the enhancement of electron anomalous magnetic moment included. New references adde

    Radiative corrections to e+eH+He^+ e^- \to H^+ H^-: THDM versus MSSM

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    One loop radiative corrections to e+eH+He^+e^-\to H^+ H^- are considered at future linear collider energies, in the general type II Two Higgs Doublet Model (THDM) and in the Minimal Supersymmetric Standard Model-like (MSSM) Higgs sector. To make the comparison between THDM and MSSM tractable, we have introduced a quasi-SUSY parameterization which preserves all the tree-level Higgs mass-sum-rules of the MSSM, and involves just 3 free parameters in the Higgs sector (instead of 7 in the general THDM) and comprises the MSSM as a particular case. The model-independent soft photon contribution is isolated and shown to be substantial. Important effects come also from the contribution of the model dependent h0H+Hh^0 H^+ H^- and H0H+HH^0 H^+ H^- vertices to the final state. In the MSSM, the contribution of the Higgs sector is moderate (a few percent) while in the THDM and both for small and large tanβ\tan \beta important effects (+30\sim +30%) can be found.Comment: 46 pages, LaTeX, 9 figures, shortened and revised version, to be published in Nuclear Physics

    Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease

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    BACKGROUND/AIMS: Accelerated atherosclerosis in chronic kidney disease (CKD) is preceded by endothelial dysfunction (ED), which exhibits a proinflammatory and prothrombotic phenotype and enhanced oxidative stress. In this study, the effect of several compounds with anti-inflammatory and/or antioxidant properties on uremia-induced endothelial dysfunction has been evaluated in an in vitro model. METHODS: Endothelial cells (ECs) were exposed to sera from uremic patients in the absence and presence of the flavonoids apigenin, genistein and quercetin, the antioxidant enzyme mimetics (AEM) ebselen (glutathione peroxidase mimetic), EUK-134 and EUK-118 (both superoxide dismutase mimetics), and the pharmacological drug N-acetylcysteine (NAC). We explored changes in the expression of adhesion receptors on the cell surface, by immunofluorescence, the production of radical oxygen species (ROS), by fluorescence detection, and the activation of signaling proteins related to inflammation, by both a phosphospecific antibody cell-based ELISA and immunoblotting techniques. RESULTS: Uremic media induced a significantly increased expression of ICAM-1, overproduction of radical oxygen species (ROS) and activation of p38 mitogen activated protein kinase (p38MAPK) and Nuclear Factor kB (NFkB) in ECs. Quercetin, the AEM and NAC showed a significant inhibitory effect on both ICAM-1 expression and ROS generation (p<0.05). All the compounds reduced p38MAPK activation, but only the AEM, especially ebselen, and NAC, both potentiating the glutathione peroxidase pathway, also inhibited NFkB activation. These two compounds were capable of increasing endothelial glutathione levels, especially in response to uremia. CONCLUSION: Our results indicate that the potentiation of the antioxidant pathways can be an effective strategy to improve endothelial dysfunction in uremia and a potential target to reduce the cardiovascular risk in this population
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