Correlation Functions in the Multiple Ising Model Coupled to Gravity

The model of p Ising spins coupled to 2d gravity, in the form of a sum over planar phi-cubed graphs, is studied and in particular the two-point and spin-spin correlation functions are considered. We first solve a toy model in which only a partial summation over spin configurations is performed and, using a modified geodesic distance, various correlation functions are determined. The two-point function has a diverging length scale associated with it. The critical exponents are calculated and it is shown that all the standard scaling relations apply. Next the full model is studied, in which all spin configurations are included. Many of the considerations for the toy model apply for the full model, which also has a diverging geometric correlation length associated with the transition to a branched polymer phase. Using a transfer function we show that the two-point and spin-spin correlation functions decay exponentially with distance. Finally, by assuming various scaling relations, we make a prediction for the critical exponents at the transition between the magnetized and branched polymer phases in the full model.Comment: 29 pages, LaTeX, uses epsf macro, 5 figure

Reconnection of Colliding Cosmic Strings

For vortex strings in the Abelian Higgs model and D-strings in superstring theory, both of which can be regarded as cosmic strings, we give analytical study of reconnection (recombination, inter-commutation) when they collide, by using effective field theories on the strings. First, for the vortex strings, via a string sigma model, we verify analytically that the reconnection is classically inevitable for small collision velocity and small relative angle. Evolution of the shape of the reconnected strings provides an upper bound on the collision velocity in order for the reconnection to occur. These analytical results are in agreement with previous numerical results. On the other hand, reconnection of the D-strings is not classical but probabilistic. We show that a quantum calculation of the reconnection probability using a D-string action reproduces the nonperturbative nature of the worldsheet results by Jackson, Jones and Polchinski. The difference on the reconnection -- classically inevitable for the vortex strings while quantum mechanical for the D-strings -- is suggested to originate from the difference between the effective field theories on the strings.Comment: 29 pages, 14 eps figures, JHEP style; references added, typos correcte

COVAD survey 2 long-term outcomes: unmet need and protocol

Vaccine hesitancy is considered a major barrier to achieving herd immunity against COVID-19. While multiple alternative and synergistic approaches including heterologous vaccination, booster doses, and antiviral drugs have been developed, equitable vaccine uptake remains the foremost strategy to manage pandemic. Although none of the currently approved vaccines are live-attenuated, several reports of disease flares, waning protection, and acute-onset syndromes have emerged as short-term adverse events after vaccination. Hence, scientific literature falls short when discussing potential long-term effects in vulnerable cohorts. The COVAD-2 survey follows on from the baseline COVAD-1 survey with the aim to collect patient-reported data on the long-term safety and tolerability of COVID-19 vaccines in immune modulation. The e-survey has been extensively pilot-tested and validated with translations into multiple languages. Anticipated results will help improve vaccination efforts and reduce the imminent risks of COVID-19 infection, especially in understudied vulnerable groups

Study of doubly strange systems using stored antiprotons

Bound nuclear systems with two units of strangeness are still poorly known despite their importance for many strong interaction phenomena. Stored antiprotons beams in the GeV range represent an unparalleled factory for various hyperon-antihyperon pairs. Their outstanding large production probability in antiproton collisions will open the floodgates for a series of new studies of systems which contain two or even more units of strangeness at the P‾ANDA experiment at FAIR. For the first time, high resolution γ-spectroscopy of doubly strange ΛΛ-hypernuclei will be performed, thus complementing measurements of ground state decays of ΛΛ-hypernuclei at J-PARC or possible decays of particle unstable hypernuclei in heavy ion reactions. High resolution spectroscopy of multistrange Ξ−-atoms will be feasible and even the production of Ω−-atoms will be within reach. The latter might open the door to the |S|=3 world in strangeness nuclear physics, by the study of the hadronic Ω−-nucleus interaction. For the first time it will be possible to study the behavior of Ξ‾+ in nuclear systems under well controlled conditions

Does the impact of COVID-19 on patients with systemic sclerosis change over time?

ObjectiveThe outcome of patients with COVID-19 improved over the pandemic, including patients with systemic rheumatic diseases. However, data on patients with systemic sclerosis (SSc) are lacking. This study aimed to assess the outcome of patients with both SSc and COVID-19 over several waves.MethodsPatients with both SSc and COVID-19 who were registered in the European Scleroderma Trials and Research group (EUSTAR) were collected between April 2020 and April 2021. Patients were assigned to waves 1, 2, or 3 depending on the date of their COVID-19 diagnosis. Primary endpoints were death, intensive care unit stay, or ventilatory support (severe outcome). Subgroup analyses of patients who were hospitalized or died were conducted. General and SSc-specific characteristics and treatment were compared over the waves. Descriptive statistics and multivariate logistic regression were applied.ResultsA total of 333 patients were included; 57 patients (17%) had a severe outcome, and 30 patients (9%) died. Compared to wave 1, significantly fewer patients with SSc suffered from severe COVID-19 in waves 2 and 3 (28.2% vs 9.8% and 12.7%; P P P = 0.001), and fewer patients died (15.7% vs 5.0% and 7.5%; P = 0.011). Patients were significantly younger, more often men, had less frequent arterial hypertension, and less SSc cardiac involvement over waves 1 to 3. Patients received significantly less medium to high doses of corticosteroids as they did SSc treatment.ConclusionThe outcome of patients with both SSc and COVID-19 improved significantly over time because of intrinsic and extrinsic factors.Pathophysiology and treatment of rheumatic disease