Professional coaching: an alternative to continuing education

O presente estudo tem como objetivo principal analisar e compreender a perceção de diferentes gestores de Pequenas e Médias empresas (PME) sobre o processo de coaching. Para o efeito, investigou-se sobre as organizações positivas, clima e cultura organizacionais, formação profissional e coaching, tema central do estudo. Procurou-se enquadrar o processo de coaching no âmbito das organizações positivas, caracterizadas por uma cultura organizacional adaptativa e estimulante, e com práticas formativas convergentes com o desenvolvimento profissional. A metodologia de investigação subjacente ao estudo é de cariz qualitativa, tendo-se utilizado como técnica de recolha de dados a entrevista semiestruturada. Para o efeito, foram realizadas cinco entrevistas a diferentes gestores de empresas. Pela análise dos discursos dos entrevistados, pode afirmar-se que os planos de formação profissional das empresas, incidem em áreas técnicas e de desenvolvimento pessoal, verificando-se que apenas uma empresa utiliza o coaching como método de desenvolvimento profissional. As restantes empresas utilizam outros métodos de formação e desenvolvimento de competências, verificando-se, no discurso dos entrevistados uma valorização das soft skills e não apenas de competências técnicas. Os gestores entrevistados consideram o processo de feedback importante para o desenvolvimento profissional dos trabalhadores e admitem que um aspeto a melhorar na relação chefia-trabalhador é o processo de comunicação. A partir da pesquisa realizada é possível perceber que o coaching é uma prática conhecida, mas pouco praticada pelos gestores de PME entrevistados, sendo que para a maioria, esse conhecimento resulta apenas de “ouvir falar”The main objective of this study is to analyze and understand the perception of different managers of Small and Medium Enterprises (SME) about the coaching process in a business context. For this purpose, research was conducted on positive organizations, organizational climate, and culture, vocational training, and coaching, the central theme of the study. The coaching process was framed in the context of positive organizations, with an adaptive and stimulating organizational culture, and with training practices convergent with professional development. The research method underlying the study is qualitative in nature, and a semi-structured interview was used as a data collection technique. For this purpose, five interviews were conducted with different managers from SME. Through the analysis of the interviewees discourse it can be said that the training plans of the company’s focus on technical areas and personal development and that only one company uses coaching as a method of professional development. The remaining companies use other methods of training and development of skills, and in the managers’ discourse an appreciation of soft skills and not only technical skills can be perceived. The interviewed managers consider the feedback process important for the professional development of employees and admit that one aspect to be improved in the manager-employee relationship is the communication process. From the survey, it is possible to conclude that coaching is a known practice, but hardly enforced by the interviewed SME managers, and in some cases, this knowledge results only from hearsayinfo:eu-repo/semantics/publishedVersio

Comparative photodynamic inactivation of bioluminescent E. coli by pyridinium and inverted pyridinium chlorins

Photodynamic inactivation (PDI) is a therapeutic approach in study due to the ability to reduce or completely eliminate the bacterial strains without the development of resistance mechanisms. In this therapeutic methodology the cationic chlorins (Chls) with pyridinium or inverted pyridinium moieties are one of the photosensitizers exploited in our biological approaches. In this context, we synthesized and characterized new free-base and zinc(II) complexes of pyridinium or inverted pyridinium Chl derivatives (1b, 2, 2a and 2b, respectively) for the inactivation of Escherichia coli (E. coli). The PDI assay was performed with white light irradiation delivered at a fluence rate of 25 mW cm−2. The obtained results of this study demonstrate high PDI efficiency of the zinc(II) metallated Chl 1b, reaching the detection limit of the bioluminescent method (5.2 log reduction) in 45 min of irradiation.publishe

Influence of the meso-substituents of zinc porphyrins in dye-sensitized solar cell efficiency with improved performance under short periods of white light illumination

The sensitization activity of four zinc metalloporphyrin dyes: meso-tetrakis(4-pyridyl)porphyrinato Zn(II) (a), meso-triphenyl-(4-carboxyphenyl)porphyrinato Zn(II) (b), meso-tetrakis(4-carboxyphenyl)porphyrinato Zn(II) (c) and meso-tripyridyl(4-carboxyphenyl)porphyrinato Zn(II) (d) is reported here, in terms of current-potential curve, open-circuit potential, fill factor, and overall solar energy conversion efficiency which have been evaluated under 100 mW/cm2 light intensity and their performances compared to the benchmark N719 (di-tetrabutylammonium cis-bis(isothiocyanato)bis(2,2′-bipyridyl-4,4′-dicarboxylato) ruthenium(II)). This work focus the structural aspects of dyes with anchoring groups using TiO2-based Dye Sensitized Solar Cells (DSSCs), which includes pyridyl and carboxyphenyl acid groups and argue how the combination of both anchoring groups, in the same structure, may allow relevant optimization of DSSCs performance in the near future. Also, a noticeable improvement in the photovoltaic performance of all dyes, reaching a maximum increase from 25% to 69% in the overall DSSC efficiency under short periods of white light illumination is discussed.publishe

Characterizing the Aqueous Geochemical History at Tyrrhena Terra, Mars

Tyrrhena Terra is an intriguing region of Mars extending from the southern part of Isidis Basin at the Libya Montes southward to Hellas Basin. Noachian and Hesperian basement rocks are covered by Syrtis lavas, especially in the northwestern part of Tyrrhena Terra and the surface is carved by craters and fluvial features. The central region is marked by the craters Jarry-Desloges, Owen, and Briault, and contains abundant Fe/Mg-rich phyllosilicates and olivine-bearing outcrops in Noachian-Hesperian terrain [1,2]. Many of the phyllosilicates in this region are located in crater ejecta and in central crater mounds, consistent with uplift of ancient materials, but some are present in dissected terrains. We are investigating the mineralogy and geology of this region through a coordinated study using TES, THEMIS, CRISM multispectral strips, CTX and HRSC imagery, and HRSC digital elevation models at a regional scale, as well as CRISM targeted images and HiRISE views of the surface at a closer scale. The phyllosilicate spectra across the central Tyrrhena Terra region (see attached figure) are most consistent with chlorite, Fe/Mg-smectite, and mixed smectite-chlorite. A few hydrated silica and zeolite outcrops are also present. This mineralogy is consistent with higher temperature processes than the primarily Fe/Mg-smectite and carbonate spectra observed in the Libya Montes region [3,4]. A few sites towards the east of our study site contain more Fe/Mg-smectite than chlorite and additional hydrated phases including sulfates, which likely represent a different formation environment. Ongoing investigations of the targeted CRISM images at the eastern part of this area are characterizing the stratigraphy of these aqueous units and their association with higher temperature units towards the west and smectite-carbonate units towards the north

[Avian cytogenetics goes functional] Third report on chicken genes and chromosomes 2015

High-density gridded libraries of large-insert clones using bacterial artificial chromosome (BAC) and other vectors are essential tools for genetic and genomic research in chicken and other avian species... Taken together, these studies demonstrate that applications of large-insert clones and BAC libraries derived from birds are, and will continue to be, effective tools to aid high-throughput and state-of-the-art genomic efforts and the important biological insight that arises from them

Inhibitors of trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.

Chagas disease remains one of the most neglected diseases in the world despite being the most important parasitic disease in Latin America. The characteristic chronic manifestation of chagasic cardiomyopathy is the region's leading cause of heart-related illness, causing significant mortality and morbidity. Due to the limited available therapeutic options, new drugs are urgently needed to control the disease. Sirtuins, also called Silent information regulator 2 (Sir2) proteins have long been suggested as interesting targets to treat different diseases, including parasitic infections. Recent studies on Trypanosoma cruzi sirtuins have hinted at the possibility to exploit these enzymes as a possible drug targets. In the present work, the T. cruzi Sir2 related protein 1 (TcSir2rp1) is genetically validated as a drug target and biochemically characterized for its NAD+-dependent deacetylase activity and its inhibition by the classic sirtuin inhibitor nicotinamide, as well as by bisnaphthalimidopropyl (BNIP) derivatives, a class of parasite sirtuin inhibitors. BNIPs ability to inhibit TcSir2rp1, and anti-parasitic activity against T. cruzi amastigotes in vitro were investigated. The compound BNIP Spermidine (BNIPSpd) (9), was found to be the most potent inhibitor of TcSir2rp1. Moreover, this compound showed altered trypanocidal activity against TcSir2rp1 overexpressing epimastigotes and anti-parasitic activity similar to the reference drug benznidazole against the medically important amastigotes, while having the highest selectivity index amongst the compounds tested. Unfortunately, BNIPSpd failed to treat a mouse model of Chagas disease, possibly due to its pharmacokinetic profile. Medicinal chemistry modifications of the compound, as well as alternative formulations may improve activity and pharmacokinetics in the future. Additionally, an initial TcSIR2rp1 model in complex with p53 peptide substrate was obtained from low resolution X-ray data (3.5 Å) to gain insight into the potential specificity of the interaction with the BNIP compounds. In conclusion, the search for TcSir2rp1 specific inhibitors may represent a valuable strategy for drug discovery against T. cruzi

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19

National identity predicts public health support during a global pandemic

Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = −0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics.publishedVersio

Wearable Biomonitoring Platform for the Assessment of Stress and its Impact on Cognitive Performance of Firefighters: An Experimental Study

Background: Stress is a complex process with an impact on health and performance. The use of wearable sensor-based monitoring systems offers interesting opportunities for advanced health care solutions for stress analysis. Considering the stressful nature of firefighting and its importance for the community’s safety, this study was conducted for firefighters. Objectives: A biomonitoring platform was designed, integrating different biomedical systems to enable the acquisition of real time Electrocardiogram (ECG), computation of linear Heart Rate Variability (HRV) features and collection of perceived stress levels. This platform was tested using an experimental protocol, designed to understand the effect of stress on firefighter’s cognitive performance, and whether this effect is related to the autonomic response to stress. Method: The Trier Social Stress Test (TSST) was used as a testing platform along with a 2-Choice Reaction Time Task. Linear HRV features from the participants were acquired using an wearable ECG. Self-reports were used to assess perceived stress levels. Results: The TSST produced significant changes in some HRV parameters (AVNN, SDNN and LF/HF) and subjective measures of stress, which recovered after the stress task. Although these short-term changes in HRV showed a tendency to normalize, an impairment on cognitive performance was found after performing the stress event. Conclusion: Current findings suggested that stress compromised cognitive performance and caused a measurable change in autonomic balance. Our wearable biomonitoring platform proved to be a useful tool for stress assessment and quantification. Future studies will implement this biomonitoring platform for the analysis of stress in ecological settings