390 research outputs found

    Accounting for biological and physical sources of acoustic backscatter improves estimates of zooplankton biomass

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    Author Posting. © NRC Canada, 2008. This is the author's version of the work. It is posted here by permission of NRC Canada for personal use, not for redistribution. The definitive version was published in Canadian Journal of Fisheries and Aquatic Sciences 65 (2008): 1321-1333, doi:10.1139/F08-047.In order to convert measurements of backscattered acoustic energy to estimates of abundance and taxonomic information about the zooplankton community, all of the scattering processes in the water column need to be identified and their scattering contributions quantified. Zooplankton populations in the eastern edge of Wilkinson Basin in the Gulf of Maine in the Northwest Atlantic were surveyed in October 1997. Net tow samples at different depths, temperature and salinity profiles, and multiple frequency acoustic backscatter measurements from the upper 200 meters of the water column were collected. Zooplankton samples were identified, enumerated, and measured. Temperature and salinity profiles were used to estimate the amount of turbulent microstructure in the water column. These data sets were used with theoretical acoustic scattering models to calculate the contributions of both biological and physical scatterers to the overall measured scattering level. The output of these predictions shows that the dominant source of acoustic backscatter varies with depth and acoustic frequency in this region. By quantifying the contributions from multiple scattering sources, acoustic backscatter becomes a better measure of net-collected zooplankton biomass.This work was supported by the Office of Naval 540 Research (Grants #N00014-00-1-0052 and N00014-01-1-0166)

    Feeding a city – Leicester as a case study of the importance of allotments for horticultural production in the UK

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    The process of urbanization has detached a large proportion of the global population from involvement with food production. However, there has been a resurgence in interest in urban agriculture and there is widespread recognition by policy-makers of its potential contribution to food security. Despite this, there is little data on urban agricultural production by non-commercial small-scale growers. We combine citizen science data for self-provisioning crop yields with field-mapping and GIS-based analysis of allotments in Leicester, UK, to provide an estimate of allotment fruit and vegetable production at a city-scale. In addition, we examine city-scale changes in allotment land provision on potential crop production over the past century. The average area of individual allotment plots used to grow crops was 52%. Per unit area yields for the majority of crops grown in allotments were similar to those of UK commercial horticulture. We estimate city-wide allotment production of >1200 t of fruit and vegetables and 200 t of potatoes per annum, equivalent to feeding >8500 people. If the 13% of plots that are completely uncultivated were used this could increase production to >1400 t per annum, feeding ~10,000 people, however this production may not be located in areas where there is greatest need for increased access to fresh fruits and vegetables. The citywide contribution of allotment cultivation peaked in the 1950s when 475 ha of land was allotments, compared to 97 ha currently. This suggests a decline from >45,000 to <10,000 of people fed per annum. We demonstrate that urban allotments make a small but important contribution to the fruit and vegetable diet of a UK city. However, further urban population expansion will exert increasing development pressure on allotment land. Policy-makers should both protect allotments within cities, and embed urban agricultural land within future developments to improve local food security

    The impact of technology on the changing practice of lung SBRT

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    Stereotactic body radiotherapy (SBRT) for lung tumours has been gaining wide acceptance in lung cancer. Here, we review the technological evolution of SBRT delivery in lung cancer, from the first treatments using the stereotactic body frame in the 1990's to modern developments in image guidance and motion management. Finally, we discuss the impact of current technological approaches on the requirements for quality assurance as well as future technological developments

    Assessing the direct resource requirements of urban horticulture in the United Kingdom : a citizen science approach

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    Interest in urban food production is growing; recent research has highlighted its potential to increase food security and reduce the environmental impact of food production. However, resource demands of urban horticulture are poorly understood. Here, we use allotment gardens in the United Kingdom to investigate resource demands of urban horticultural production across the country. We conducted a nationwide citizen science project using year-long allotment ‘diaries’ with allotment gardeners (n = 163). We analysed a variety of resources: transportation; time; water use; inputs of compost, manure and topsoil; and inputs of fertilisers, pest control and weed control. We found that, overall, an allotment demands 87 annual visits, travelling 139 km to and from the plot; 7 fertiliser additions; 4 pest control additions; and 2 weed control additions. On average, each kilogram of food produced used 0.4 hours’ labour, 16.9 L of water, 0.2 L of topsoil, 2.2 L of manure, and 1.9 L of compost. As interest in urban horticultural production grows, and policy makers build urban horticultural spaces into future sustainable cities, it is of key importance that this is carried out in a way that minimises resource requirements, and we demonstrate here that avenues exist for the diversion of municipal compostable waste and household-level city food waste for this purpose

    quasiharmonic equations of state for dynamically-stabilized soft-mode materials

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    We introduce a method for treating soft modes within the analytical framework of the quasiharmonic equation of state. The corresponding double-well energy-displacement relation is fitted to a functional form that is harmonic in both the low- and high-energy limits. Using density-functional calculations and statistical physics, we apply the quasiharmonic methodology to solid periclase. We predict the existence of a B1--B2 phase transition at high pressures and temperatures

    Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates

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    PURPOSE: P-glycoprotein (Pgp) is a transmembrane drug efflux pump that is expressed in multidrug-resistant cancer cells and in a variety of normal tissues, including brain capillary endothelial cells which comprise the blood-brain barrier. We studied the effects of the Pgp inhibitor, cyclosporin A (CsA), on the cerebrospinal fluid (CSF) penetration of the Pgp substrate, doxorubicin, in non-human primates. METHODS: The animals received doxorubicin alone (2.0 mg/kg i.v. over 60 min) or doxorubicin (1 mg/kg i.v. over 60 min) and CsA (loading dose 4.0 mg/kg i.v. over 2 h, followed by continuous infusion of 12 mg/kg per day over 48 h). Plasma and CSF were collected over 48 h and the doxorubicin concentration was measured by reverse-phase high-pressure liquid chromatography (HPLC) with fluorescence detection (detection limit 5 nM). A two-compartment model was fitted to the plasma concentration-time data. RESULTS: Pgp was demonstrated to be present in the epithelium of the choroid plexus by immunohistochemical methods, indicating that CSF drug penetration could be used as a surrogate for blood-brain barrier penetration. Steady state whole blood CsA concentrations, which were measured with a fluorescence-polarization immunoassay (TDX) that detects both CsA and its metabolites, ranged from 551-1315 microg/l at 24 h. The clearance of doxorubicin in four animals was reduced by 34%, 38%, 45% and 49% when given with CsA. The doxorubicin concentration in the CSF was <5 nM in all animals, both after doxorubicin alone and doxorubicin with CsA. CONCLUSIONS: The Pgp inhibitor, CsA, at a concentration that alters systemic clearance of doxorubicin, does not appear to significantly increase the CSF penetration of doxorubicin

    Etherscapes: Massless, Elastic, Technology and Control

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    This thesis is an exploration into the ether of the digital aesthetic. It attempts to capture a segment of the continually morphing space then deconstruct and analyse it through electronic and new media art. Herein you will find a questioning of technology and control within electronic and new media art as an investigation into better understanding the current media image and visual culture that so powerfully influences the modern social construct. By nature this argument has existed for some years but only now with advancements in technology and more affordable realisation of ideas by media artists, the topic of the digital aesethetic, technology and control has become relevant for popular debate. As war lingers in our minds, terrorism hits headlines, and experiements in cloning human DNA take place, the technology that society demands can only necessarily be seen as a major contributing factor to today's strange times. However, strange or not, the questions I wish to discuss; Does technology determine contemporary society or do we determine technology? Where does the control exist

    Intersection Graphs of L-Shapes and Segments in the Plane

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    An L-shape is the union of a horizontal and a vertical segment with a common endpoint. These come in four rotations: ⌊,⌈,⌋ and ⌉. A k-bend path is a simple path in the plane, whose direction changes k times from horizontal to vertical. If a graph admits an intersection representation in which every vertex is represented by an ⌊, an ⌊ or ⌈, a k-bend path, or a segment, then this graph is called an ⌊-graph, ⌊,⌈-graph, B k -VPG-graph or SEG-graph, respectively. Motivated by a theorem of Middendorf and Pfeiffer [Discrete Mathematics, 108(1):365–372, 1992], stating that every ⌊,⌈-graph is a SEG-graph, we investigate several known subclasses of SEG-graphs and show that they are ⌊-graphs, or B k -VPG-graphs for some small constant k. We show that all planar 3-trees, all line graphs of planar graphs, and all full subdivisions of planar graphs are ⌊-graphs. Furthermore we show that all complements of planar graphs are B 19-VPG-graphs and all complements of full subdivisions are B 2-VPG-graphs. Here a full subdivision is a graph in which each edge is subdivided at least once

    Bound Pairs: Direct Evidence for Long-range Attraction between Like-Charged Colloids

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    We report observations of stable bound pairs in very dilute deionized aqueous suspensions of highly charged polystyrene colloidal particles, with monovalent counterions, using a confocal laser scanning microscope. Through an analysis of several thousands of time series of confocal images recorded deep inside the bulk suspension, we find that the measured pair-potential, U(r) has a long-range attractive component with well depths larger than the thermal energy. These observations provide a direct and unequivocal evidence for the existence of long-range attraction in U(r) of like-charged colloidal particles.Comment: 8 pages, 4 figures, submitted to Phys. Rev. Let

    NGO Legitimacy: Four Models

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    The aim of this paper is to examine NGOs’ legitimacy in the context of global politics. In order to yield a better understanding of NGOs’ legitimacy at the international level it is important to examine how their legitimacy claims are evaluated. This paper proposes dividing the literature into four models based on the theoretical and analytical approaches to their legitimacy claims: the market model, social change model, new institutionalism model and the critical model. The legitimacy criteria generated by the models are significantly different in their analytical scope of how one is to assess the role of NGOs operating as political actors contributing to democracy. The paper argues that the models present incomplete, and sometimes conflicting, views of NGOs’ legitimacy and that this poses a legitimacy dilemma for those assessing the political agency of NGOs in world politics. The paper concludes that only by approaching their legitimacy holistically can the democratic role of NGOs be explored and analysed in the context of world politics
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