245 research outputs found
Optoelectronic Reservoir Computing
Reservoir computing is a recently introduced, highly efficient bio-inspired
approach for processing time dependent data. The basic scheme of reservoir
computing consists of a non linear recurrent dynamical system coupled to a
single input layer and a single output layer. Within these constraints many
implementations are possible. Here we report an opto-electronic implementation
of reservoir computing based on a recently proposed architecture consisting of
a single non linear node and a delay line. Our implementation is sufficiently
fast for real time information processing. We illustrate its performance on
tasks of practical importance such as nonlinear channel equalization and speech
recognition, and obtain results comparable to state of the art digital
implementations.Comment: Contains main paper and two Supplementary Material
Random walks and random numbers from supercontinuum generation
We report a numerical study showing how the random intensity and phase fluctuations across the bandwidth of a broadband optical supercontinuum can be interpreted in terms of the random processes of random walks and LĂ©vy flights. We also describe how the intensity fluctuations can be applied to physical random number generation. We conclude that the optical supercontinuum provides a highly versatile means of studying and generating a wide class of random processes at optical wavelengths
095 PHARMACOLOGY OF THE STR/ORT MOUSE AS A MODEL FOR OSTEOARTHRITIS: RESPONSIVENESS TO EP4 ANTAGONISTS AND AGGRECANASE INHIBITORS
Absence of increased genomic variants in the cyanobacterium Chroococcidiopsis exposed to Marsâlike conditions outside the space station
Despite the increasing interest in using microbialâbased technologies to support human space exploration, many unknowns remain not only on bioprocesses but also on microbial survivability and genetic stability under nonâEarth conditions. Here the desert cyanobacterium Chroococcidiopsis sp. CCMEE 029 was investigated for robustness of the repair capability of DNA lesions accumulated under Marsâlike conditions (UV radiation and atmosphere) simulated in low Earth orbit using the EXPOSEâR2 facility installed outside the International Space Station. Genomic alterations were determined in
a spaceâderivate of Chroococcidiopsis sp. CCMEE 029 obtained upon reactivation on Earth of the spaceâexposed cells. Comparative analysis of wholeâgenome sequences showed no increased variant numbers in the spaceâderivate compared to triplicates of the reference strain maintained on the ground. This result advanced cyanobacteriaâbased technologies to support human space exploration
Breeding strategy shapes the composition of bacterial communities in female Nile tilapia reared in a recirculating aquaculture system
publishedVersio
Real time noise and wavelength correlations in octave-spanning supercontinuum generation
We use dispersive Fourier transformation to measure shot-to-shot spectral
instabilities in femtosecond supercontinuum generation. We study both the onset
phase of supercontinuum generation with distinct dispersive wave generation, as
well as a highly-unstable supercontinuum regime spanning an octave in
bandwidth. Wavelength correlation maps allow interactions between separated
spectral components to be identified, even when such interactions are not
apparent in shot-to-shot or average measurements. Experimental results are
interpreted using numerical simulations. Our results show the clear advantages
of dispersive Fourier transformation for studying spectral noise during
supercontinuum generation.Comment: 14 pages, 5 figure
Real-time full bandwidth measurement of spectral noise in supercontinuum generation
The ability to measure real-time fluctuations of ultrashort pulses
propagating in optical fiber has provided significant insights into fundamental
dynamical effects such as modulation instability and the formation of
frequency-shifting rogue wave solitons. We report here a detailed study of
real-time fluctuations across the full bandwidth of a fiber supercontinuum
which directly reveals the significant variation in measured noise statistics
across the spectrum, and which allows us to study correlations between widely
separated spectral components. For two different propagation distances
corresponding to the onset phase of spectral broadening and the fully-developed
supercontinuum, we measure real time noise across the supercontinuum bandwidth,
and we quantify the supercontinuum noise using statistical higher-order moments
and a frequency-dependent intensity correlation map. We identify correlated
spectral regions within the supercontinuum associated with simultaneous
sideband generation, as well as signatures of pump depletion and soliton-like
pump dynamics. Experimental results are in excellent agreement with
simulations
Elevated soluble Flt1 mediates an anti-angiogenic state in patients with ANCA-associated vasculitis
International audiencen.
Two-omics data revealed commonalities and differences between Rpv12- and Rpv3-mediated resistance in grapevine
Plasmopara viticola is the causal agent of grapevine downy mildew (DM). DM resistant varieties deploy effector-triggered immunity (ETI) to inhibit pathogen growth, which is activated by major resistance loci, the most common of which are Rpv3 and Rpv12. We previously showed that a quick metabolome response lies behind the ETI conferred by Rpv3 TIR-NB-LRR genes. Here we used a grape variety operating Rpv12-mediated ETI, which is conferred by an independent locus containing CC-NB-LRR genes, to investigate the defence response using GC/MS, UPLC, UHPLC and RNA-Seq analyses. Eighty-eight metabolites showed significantly different concentration and 432 genes showed differential expression between inoculated resistant leaves and controls. Most metabolite changes in sugars, fatty acids and phenols were similar in timing and direction to those observed in Rpv3-mediated ETI but some of them were stronger or more persistent. Activators, elicitors and signal transducers for the formation of reactive oxygen species were early observed in samples undergoing Rpv12-mediated ETI and were paralleled and followed by the upregulation of genes belonging to ontology categories associated with salicylic acid signalling, signal transduction, WRKY transcription factors and synthesis of PR-1, PR-2, PR-5 pathogenesis-related proteins
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